Unilateral Psoriasis on the Left Leg and Poliomyelitis of the Right Leg: A Case Report and Review of the Etiology

김종욱,배경남,손진화,신기혁,Hoon Soo Kim,고현창,Moon Bum Kim,Byung Soo Kim 대한피부과학회 2023 Annals of Dermatology Vol.35 No.-

Psoriasis is a common immune-mediated, inf lammatory skin disease. However, unilateral psoriasis is rare and few cases have been reported. A 59-year-old male with a polio-affected right leg presented with exfoliative skin on the left leg for three months. He had been treated under the diagnosis of contact dermatitis with secondary infection. After the exfoliative skin lesions improved, psoriatic papules were noted, which was ultimately diagnosed as pso- riasis and successfully treated with topical steroid and vitamin D agents. We propose that the Koebner phenomenon has acted as the triggering and aggravating factor of unilateral psoriasis in this patient.

RF 파워에 따라 스퍼터된 Al doped ZnO 박막의 구조적, 광학적, 전기적 특성

김종욱,김덕규,김홍배,Kim, Jong-Wook,Kim, Deok-Kyu,Kim, Hong-Bae 한국전기전자재료학회 2011 전기전자재료학회논문지 Vol.24 No.3

We have studied structural, optical, and electrical properties of the Al-doped ZnO (AZO) thin films being usable in transparent conducting oxides. The AZO thin films were deposited on the corning 1737 glass plate by the RF magnetron sputtering system. To find optimal properties of AZO for transparent conducting oxides, the RF power in sputtering process was varied as 40 W, 60 W, and 80 W, respectively. As RF power increased, the crystallinity of AZO thin film was decreased, the optical bandgap of AZO thin film increased. The transmittance of the film was over 80% in the visible light range regardless of the changes in RF power. The measurement of Hall effect characterizes the whole thin film as n-type, and the electrical property was improved with increasing RF power. The structural, optical, and electrical properties of the AZO thin films were affected by Al dopant content in AZO thin film.

인공 유방 확대술을 받은 환자의 유방암 치료 시 크기에 따른 반대 측 유방의 피폭 선량 및 차폐 효율 평가

김종욱,우헌,정현학,김경아,김찬용,유숙현,Kim, Jong Wook,Woo, Heon,Jeong, Hyeon Hak,Kim, Kyeong Ah,Kim, Chan Yong,Yoo, Suk Hyun 대한방사선치료학회 2014 대한방사선치료학회지 Vol.26 No.2

목 적 : 인공 유방 확대술을 받은 환자가 유방암 방사선치료를 받을 경우 유방의 크기별로 치료 조사야와의 거리에 따른 치료반대 측 유방조직에 피폭되는 선량 및 차폐의 효율성을 평가해 보고자 한다. 대상 및 방법 : 인체팬텀(Rando-phantom)을 이용하여 유방 모형의 크기별 (200 cc ~ 500 cc) CT영상을 획득한 후 크기 별로 일 선량 180 cGy의 왼쪽 유방암 방사선 치료계획을 세웠다. 유방 모형이 커질수록 치료 반대 측 유방모형의 표면과 X선의 진행지점 사이에 발생하는 거리가 가까워지게 설정하였고, 체표에 입사하는 선속중심축을 기준으로 3 cm, 6 cm 떨어진 점에서 반대측 유방 표면에 수직으로 내린 거리를 각 A point, B point로 설정하였다. 그리고 유두지점에서 외측으로 2 cm 되는 점을 C point, 체표중앙에서 외측으로 6 cm 되는 점을 D point로 설정하였다. 유방 모형의 크기별로 각 측정지점에 MOSFET을 부착하여 6 MV, 10 MV, 15 MV의 X선 에너지로 조사하여 측정하였다. 이와 동일한 조건으로 납 2 mm의 두께로 차폐한 후의 선량 값과 납 2 mm 아래에 bolus 3 mm를 부착하여 차폐한 후의 선량 값을 얻었다. 결 과 : 유방 모형이 200 cc에서 500 cc로 커짐에 따라 유방 모형의 표면과 X선의 진행지점과의 거리가 A point에서는 2.14 cm에서 최대 1.23 cm으로 근접하였고 B point에서는 2.55 cm에서 1.31 cm으로 근접하였다. 유방 모형의 크기에 따라 180 cGy 기준으로 200 cc 대비 500 cc의 산란선 측정값이 A point에서 3.22 ~ 4.17%, B point에서 4.06 ~ 6.22%, C point는 0.4~0.5% 증가하였고, D point에서는 크기별로 측정값의 차이가 0.4% 미만이었다. X선 에너지가 커짐에 따라 6 MV 대비 15 MV X선에서 180cGy 기준으로 산란선이 A point에서는 4.06~5%, B point에서는 2.85~4.94%, C point에서는 0.74~1.65% 증가하였고, D point에서는 측정값 차이가 0.4% 미만이었다. 차폐체로 납 2 mm를 사용하였을 경우 A와 B point에서 평균 9.74%, C point에서 2.8%, D point에서 1% 미만의 산란선 감소효과가 있었고, 납과 bolus를 함께 차폐하였을 경우 A와 B point에서 평균 9.76%, C point에서 2.2%, D point에서 1% 미만의 산란선 감소효과가 있었다. 결 론 : 일반적으로 인공 유방 확대술을 받은 환자의 경우 유방의 크기에 따라 치료 반대편 유방 표면과 치료조사야의 거리가 가까울수록 유방 표면이 받는 산란선이 증가하였다. 동일한 크기의 유방 모형에서는 사용 X선 에너지가 커질수록 산란선에 의한 피폭이 증가하는 경향을 보였고, 이는 사용 X선의 에너지 선택에 있어 유방암의 방사선 치료계획에서 허용되는 한도에서는 낮은 X선 에너지의 사용이 반대측 유방의 선량 감소에 유리할 것으로 여겨진다. Purpose : To evaluate the dose on a contralateral breast and the usefulness of shielding according to the distance between the contralateral breast and the side of the beam by breast size when patients who got breast implant receive radiation therapy. Materials and Methods : We equipped 200 cc, 300 cc, 400 cc, and 500 cc breast model on the human phantom (Rando-phantom), acquired CT images (philips 16channel, Netherlands) and established the radiation treatment plan, 180 cGy per day on the left breast (EclipseTM ver10.0.42, Varian Medical Systems, USA) by size. We set up each points, A, B, C, and D on the right(contralateral) breast model for measurement by size and by the distance from the beam and attached MOSFET at each points. The 6 MV, 10 MV and 15 MV X-ray were irradiated to the left(target) breast model and we measured exposure dose of contralateral breast model using MOSFET. Also, at the same condition, we acquired the dose value after shielding using only Pb 2 mm and bolus 3 mm under the Pb 2 mm together. Results : As the breast model is bigger from 200 cc to 500 cc, The surface of the contralateral breast is closer to the beam. As a result, from 200 cc to 500 cc, on 180 cGy basis, the measurement value of the scattered ray inclined by 3.22 ~ 4.17% at A point, 4.06 ~ 6.22% at B point, 0.4~0.5% at C point, and was under 0.4% at D point. As the X-ray energy is higher, from 6 MV to 15 MV, on 180 cGy basis, the measurement value of the scattered ray inclined by 4.06~5% at A point, 2.85~4.94% at B point, 0.74~1.65% at C point, and was under 0.4% at D point. As using Pb 2 mm for shield, scattered ray declined by average 9.74% at A and B point, 2.8% at C point, and is under 1% at D point. As using Pb 2 mm and bolus together for shield, scattered ray declined by average 9.76% at A and B point, 2.2% at C point, and is under 1% at D point. Conclusion : Commonly, in case of patients who got breast implant, there is a distance difference by breast size between the contralateral breast and the side of beam. As the distance is closer to the beam, the scattered ray inclined. At the same size of the breast, as the X-ray energy is higher, the exposure dose by scattered ray tends to incline. As a result, as low as possible energy wihtin the plan dose is good for reducing the exposure dose.

밍크정자의 성숙에 따른 전자현미경적 형태변화

김종욱,M . S . 아흐마드,W . D . 킷츠 ( J . W . Kim,M . S . Ahmad,W . D . Kitts ) 한국축산학회 1978 한국축산학회지 Vol.20 No.5

The maturation changes in viability and morphology were studied in the present investigation with spermatozoa collected from the testis, three successive parts of the epididymis and from ejaculated semen in the mink. The motility of spermatozoa was found to be significantly increased (p $lt; 0.05) during the spermatozoan passage through successive parts of the reproductive system. Ejaculated spermatozoa collected from females after mating was less active compared to that of cauda spermatozoa. While testicular spermatozoa was nor-motile, a comparatively high per cent of motility was acquired by spermatozoa during their transit in the epididymis. Although the total head length of spermatozoa changed very little, the anterior acrosomal length was significantly decreased (p$lt; 0.001) while the postacrosomal length increased significantly (p$lt; 0.05) during transit from the testis to the epididymis. The equatorial length of testicular spermatozoa was smaller than that of epididymal spermatozoa. Even though the apical length significantly decreased (p $lt; 0.001) when spermatozoa moved from the testis and caput epididymis to the corpus and cauda epididymis, the nuclear length maintained almost similar vaaues during passage through the reproductive tract The acrosomal thickness of spermatozoa significantly decreased Ip $lt; 0.001) from the testis to the epididymis. The head length of ejaculated spematozoa were smaller than those of spermatozoa obtained from the reproductive tract. Many abnormal spermatozoa were found in the testis and caput epididymis. There was an increase of separation of the cell memlbrane from the acrosome (p $lt; 0.05) as spermatozoa passed down the reproductive tract. Such cell membrane separation from the acrosome was more pronounced in ejaculated spermatozoa. There was no statistical difference between spermatozoa removed from different parts of the reproductive tract in the damage of the acrosomal membrane. The occurrence of the postacrosomal swelling significantly increased (p$lt; 0.01) from testicular and caput spermatozoa to corpus and cauda spermatozoa. Almost all ejaculated spermatozoa had swellings. The incidence of the cytoplasmic droplet significantly (p$lt; 0.001) diminished from testicular spermatozoa to epididymal spermatozoa. A few ejaculated spermatozoa had the droplet.

자원 공유 플레이스 추이적 행렬을 이용한 효율적인 교착상태 확인 정책

김종욱,이종근,Kim, Jong-Woog,Lee, Jong-Kun 한국시뮬레이션학회 2008 한국시뮬레이션학회 논문지 Vol.17 No.3

여러 개의 작업이 동시에 작동 할 때 서로 다른 작업에서 공유자원을 사용하기 위하여 상대방의 작업이 끝나기를 기다리는 상태를 교착상태라 하며 이는 시스템의 효율성과 경제성 제고에 가장 중요한 문제 중 하나이다. 지금까지 이러한 교착상태 확인은 도달성(reachability)기법이나 서브 넷(Subnet)으로 분리하여 분석하는 기법 등이 가장 많이 사용되었으나, 분석에 필요한 시간과 노력, 복잡성과 효율성에 있어서 효과적이지 못한 단점을 가지고 있다. 본 연구는 패트리 넷(Petri Net)에서 모든 플레이스(Place) 간의 관계를 나타내는 추이적(Transitive)행렬을 이용하여 교착상태가 나타날 가능성이 있는 자원공유 플레이스를 분석하여 교착상태를 검증하는 정책을 제시한다. 이를 위하여 교착상태를 확인할 수 있는 자원공유 플레이스의 관계를 정의하고, 유연생산시스템 모델을 이용하여 제안한 알고리즘의 성과를 검증한다. A deadlock is a condition in which the excessive demand for the resources being used by others causes activities to stop and it is one of the important problems in process control system to detect and prevent deadlocks. While the reachability analyze methods or divide subnets for analyzing methods are well used, it requires a lot of times and effects to analyze the detection of the deadlock status. Furthermore, it could not be effective if the model is complex or huge. Therefore, it is necessary to develop a new and more efficient deadlock detection algorithm. In this paper, a deadlock detection conditions after analyzed the Petri Net using the transitive matrix has been proposed to solve these problems. For presenting the results, the suggested deadlock detection algorithm was also adapted to an illustrated FMS (Flexible Manufacturing System) model.

백두옹탕(白頭翁湯)의 대장암 세포주 HCT-116 항암효과와 세포자멸사에 관한 연구

김종욱,문구,박찬희,이정한,지혜민,Kim, Jong-Uk,Moon, Goo,Park, Chan-Ny,Lee, Jeong-Han,Ji, Hye-Min 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.2

Objectives : To investigate the anti-cancer effect of Baekduong-tang(BDOT) against cancer cells, the signaling pathway of apoptosis was explored in human colon cancer cells. Materials and Methods : Human colon cancer cell lines, including HT-29 and HCT-116 cells, were used. Cell viability was measured by MTT assay. Apoptosis was determined by DAPI nuclei staining and flow cytometry in HCT-116 cells treated with 0.25 mg/$m{\ell}$ Baekduong-tang for 48 hrs. Results : Baekduong-tang induced the apoptosis of p53 positive HCT-116 cells with G2/M phase arrest. Treatment with Baekduong-tang led to increased expression and phosphorylation of p53 and decreased expression of CDK2 and CDK6 in HCT-116 cells. It also activated caspase-3 through caspase-10 and caspase-9 activation. Finally, Baekduong-tang induced production $H_2O_2$, superoxide anion ($O_2^-$) and NO and modulated proteins expression including SOD, NOS, Bax and Bcl-2. Conclusions : These results indicate Baekduong-tang induces apoptotic death of HCT-116 cells through G2/M phase arrest and disturbance of intracellular redox status in a p53-dependent manner.

정사각틀 초음파 모터의 변위 특성

김종욱,박충효,임정훈,정성수,김명호,박태곤,Kim, Jong-Wook,Park, Choong-Hyo,Lim, Jung-Hoon,Jeong, Seong-Su,Kim, Myong-Ho,Park, Tae-Gone 한국전기전자재료학회 2011 전기전자재료학회논문지 Vol.24 No.9

A novel design of a simple square-frame USM (ultrasonic motor) was proposed. The stator of the motor consists of a square-frame shape elastic body and four rectangular plate ceramics. The four ceramics were attached to inner surfaces of the square frame elastic body. The same phase voltages were applied to the ceramics on horizontal surfaces, and 90 degree phase difference voltage were applied to the ceramics on vertical surfaces. To find a model that generates elliptical motion at outside of the stator, the finite element analysis program ATILA was used. The analyzed results were compared to the experimental results. As result, the model EL10EH3ET0.5CL4 which generates the maximum elliptical displacement was chosen by analyzing the resonance mode according to changes in frequency.

Thin-Type 초음파모터의 설계 및 제작

김종욱,박충효,정현호,정성수,박태곤,Kim, Jong-Wook,Park, Choong-Hyo,Chong, Hyon-Ho,Jeong, Seong-Su,Park, Tae-Gone 한국전기전자재료학회 2010 전기전자재료학회논문지 Vol.23 No.7

In this paper, the characteristics of a thin-type ultrasonic motor generating elliptical displacements analyzed by FEM are presented, and then fabrication of the motor is then described. The structure of the motor consists of sixteen ceramic pieces attached to the upper and bottom surfaces of an elastic body. The principle of the motor is to apply alternating voltages which have a 90 phase difference to the attached ceramics, and then elliptical displacements are generated at four edges of the elastic body. Then the rotor is moved by the elliptical displacements. In the case of a ceramic thickness of 1.5, the highest speed was obtained at 79 kHz. In the case of a ceramic thickness of 2 mm, the highest speed was obtained at 77.5 kHz. Consequently, the speed and torque of the ultrasonic motor (USM) increased linearly with increasing applied voltage.

Survey on the Perception of Urogenital Complications in Diabetic Patients

김종욱,Ji Yun Chae,Jinwook Kim,CheolYongYoon,Mi Mi Oh,김제종,문두건 대한남성과학회 2012 The World Journal of Men's Health Vol.30 No.3

Purpose: Retinopathy, neuropathy, and nephropathy are well-known complications of diabetes; they are often expected to occur and, therefore, are usually tested for. However, urogenital complications, such as sexual and voiding dysfunctions, are less well known, and consequently, many patients are not treated appropriately despite their symptoms. Thus, we surveyed diabetic patients with regard to their perception of urogenital complications. Materials and Methods: We designed a survey for patients in our hospital who were being treated for diabetes mellitus (DM). The questionnaire included items on age, sex, treatment duration, treatment options for and the level of perception of urogenital symptoms, the presence of urogenital symptoms, and whether treatment was intended or had been initiated. Results: In total, 275 patients participated in the survey. The perception questions on DM-associated urogenital complications showed that 89 patients (32.4%) had no knowledge, 84 patients (30.5%) had some knowledge, and 102 patients (37.1%) had detailed knowledge about these complications. A total of 124 patients (45.1%) reported urogenital symptoms: 93 patients (75.0%) reported voiding dysfunction and 61 patients (49.2%) reported sexual dysfunction. Common symptoms of voiding dysfunction were urinary frequency, nocturia, sense of residual urine, weak stream, and urinary incontinence. Common symptoms of sexual dysfunction were reduced libido, and erectile and ejaculatory dysfunction. Conclusions: The survey showed that the subjective prevalence rate of urogenital symptoms in diabetic patients was 45.1%. However, only a small percentage (37.1%) of the patients cognized that these symptoms were associated with DM. Therefore, it is necessary to properly inform and educate diabetic patients on possible urogenital complications that may occur.

서태평양 지판소멸대의 해저열수분출구에서 관찰되는 황동위원소 조성변화: 열수 생성의 다양성과 마그마의 역할

김종욱,문재운,이경용,이인성,Kim, Jong-Uk,Moon, Jai-Woon,Lee, Kyeong-Yong,Lee, In-Sung 대한자원환경지질학회 2012 자원환경지질 Vol.45 No.2

해저열수시스템은 중앙해령이나 후열도확장대와 같은 해저화산대를 따라 생성된다. 해저열수시스템은 지각-맨틀과 해양의 에너지와 물질이 교환되는 장으로 이를 통해 지각과 해수의 조성이 변화하며, 해저면에 열수분출구를 침전시켜 열수생태계를 형성하고 금속광상이 만들어진다. 상대적으로 단순한 중앙해령과 달리 지판소멸지역의 해저열수시스템은 섭입되는 물질의 재순환과정에서 다양한 특성이 나타난다. 황동위원소 조성은 이러한 열수시스템의 다양성을 평가하는데 유용하다. 이 논문에서는 서태평양의 지판소멸대에서 발견된 열수분출 지역에서 채취된 열수분출구 시료의 황동위원소 조성변화를 살펴보고 이들 환경에서 열수생성의 다양성을 일으키는 요인을 고찰하였다. 지판소멸대의 열수분출구는 황화광물과 황산염광물 모두 낮은 황동위원소 조성을 갖는 것이 특징이며, 이는 마그마로부터 공급된 $SO_2$ 기체의 유입으로 해석된다. 황동위원소 조성 변화를 포함한 열수시스템의 다양성은 열수시스템 생성과정에서 마그마의 적극적인 역할을 지시한다. Seafloor hydrothermal system occurs along the volcanic mid-ocean ridge, back-arc spreading center, and other submarine volcanic regions. The hydrothermal system is one of the fundamental processes controlling the transfer of energy and matter between crust/mantle and ocean; it forms hydrothermal vents where various deepsea biological communities are inhabited and precipitates metal sulfide deposits. Hydrothermal systems at convergence plate boundaries show diverse geochemical properties due to recycle of subducted material compared to simple systems at mid-ocean ridges. Sulfur isotopes can be used to evaluate such diversity in generation and evolution of hydrothermal system. In this paper, we review the sulfur isotope composition and geochemistry of hydrothermal precipitates sampled from several hydrothermal vents in the divergent plate boundaries in the western Pacific region. Both sulfide and sulfate minerals of the hydrothermal vents in the arc and backarc tectonic settings commonly show low sulfur isotope compositions, which can be attributed to input of magmatic $SO_2$ gas. Diversity in geochemistry of hydrothermal system suggests an active role of magma in the formation of seafloor hydrothermal system.