충북대학교 / 김다운

김다운 대한검도학회 2018 대학검도보 Vol.- No.34

Characterization of Nivalenol-Producing Fusarium culmorum Isolates Obtained from the Air at a Rice Paddy Field in Korea

김다운,김기용,김희경,김주은,전순정,이철원,이향범,윤성환 한국식물병리학회 2016 Plant Pathology Journal Vol.32 No.3

Together with the Fusarium graminearum species complex, F. culmorum is a major member of the caus-al agents of Fusarium head blight on cereals such as wheat, barley and corn. It causes significantyield and quality losses and results in the contamination of grain with mycotoxins that are harmful to humans and animals. In Korea, F. culmorum is listed as a quaran-tine fungal species since it has yet to be found in the country. In this paper, we report that two isolates (J1 and J2) of F. culmorum were collected from the air at a rice paddy field in Korea. Species identification was confirmed by phylogenetic analysis using multi-locus sequence data derived from fivegenes encoding translation elongation factor, histone H3, phosphate permease, a reductase, and an ammonia ligase and by morphological comparison with reference strains. Both diagnostic PCR and chemical analysis confirmedthat these F. culmorum isolates had the capacity to produce nivalenol, the trichothecene mycotoxin, in rice substrate. In addition, both isolates were patho-genic on wheat heads and corn stalks. This is the firstreport on the occurrence of F. culmorum in Korea.

추정 사구체여과율의 해석

김다운,이하린 대한내과학회 2023 대한내과학회지 Vol.98 No.1

Glomerular filtration rate (GFR) plays an important role in the clinical evaluation of renal function, classification, prognosis prediction, and drug dosing in patients with acute or chronic kidney disease . Estimated GFR (eGFR) is calculated based on endogenous filtration markers, such as creatinine and cystatin C. These are useful markers, but it is necessary to understand the clinical settings in which eGFR, calculated using creatinine or cystatin C, may be less accurate. Several equations, including the Cockcroft and Gault, modification of diet in renal disease, and chronic kidney disease-epidemiology collaboration (CKD-EPI) equations, are used to calculate eGFR. The latter is most common because it has high accuracy and can predict prognosis. Recently, a new race-omitting CKD-EPI equation has been developed but further studies are required to determine whether it can be applied in clinical practice and research. Furthermore, careful use of eGFR is needed in acute kidney injury, kidney transplantation, and dialysis patients. Drug dosing must be guided by accurate GFR assessment. In addition to medical care, GFR assessment is also important for public health and research. Therefore, further studies are needed to reevaluate and develop the equations for accurate eGFR calculations.

산개성단 IC4665 내에 있는 변광성 빈도

김다운,백관혁,유성제,이혜인,선기영,박항,한수민,김희수 한국과학영재교육학회 2012 과학영재교육 Vol.4 No.2

The aim of this study was to investigate the variable star frequency in open cluster IC4665. For this, We observed the cluster using 4inch refrator telescope and CCD camera. After that, we searched variable star candidates. If the magnitude change of a star is larger than three times of standard deviation, we identified the star as a variable. we found that the varible star frequency of open cluster IC4665 is about 20%. 본 연구의 목적은 산개성단 IC4665를 CCD 관측을 수행하여 변광성을 찾는 것이다. 이를 위해 4인치 굴절망원경에 CCD 카메라를 연결하여 IC4665를 관측한 다음, 이 성단 내에 포함된 변광성을 찾았다. 성단내 구성원들의 변광성을 찾는 방법은 별의 밝기 변화가 관측의 허용오차보다 3배 이상 벗어난 별들을 변광성으로 판정하였다. 그 결과 측광한 93개의 성단 구성원 별들 중, 19개인 약 20%의 별이 변광성임을 알 수 있었다.

QuEChERS 잔류농약 다성분 동시분석법을 이용한 국내산 해조류의 잔류농약 모니터링

김다운,홍준호,이미진,임윤진,이슬아,김춘성 한국식품영양과학회 2022 한국식품영양과학회 학술대회발표집 Vol.2022 No.10

다중 커널을 이용한 파킨슨 환자로부터 보행 동결 진행까지의 페널티 콕스 회귀 분석

김다운,이주영 한국보건정보통계학회 2023 보건정보통계학회지 Vol.48 No.1

Objectives: The objective of this study was to investigate complex non-linear associations of multiple genetic and brain imaging factors and the interac- tions of the two factors with the risk of gait freezing for patients with Parkinson’s disease (PD). Methods: We employed a penalized kernel machine Cox proportional hazard regression model. Multiple kernels were created to account for multiple genetic factors and their interactions with brain imaging factors, and we identified significant elements using the group lasso penalty. We applied the proposed method to Parkinson’s Progression Markers Initia- tive (PPMI) data. Results: We identified LRRK2 genes and the volume of six regions of interest in brain interacting with COMT, GBA, LRRK2, and SNCA genes that are associated with the occurrence of freezing of gait for PD patients. Conclusions: It was found that there is evidence of gene-brain interac- tions in freezing of gait. The proposed penalized Cox model using the kernel machine method enables us to identify the nonlinear relationship between genetic and neuroimaging factors and the occurrence of neurodegenerative diseases. .

Bio-inspired configurable multiscale extracellular matrix-like structures for functional alignment and guided orientation of cells

김다운,김장호 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.0

Inspired by the hierarchically organized protein fibers in extracellular matrix (ECM) as well as the physiological importance of multiscale topography, we developed a simple method for the design and manipulation of precisely controllable multiscale hierarchical structures. In this study, we approached a conceptual platform that can mimic the hierarchically multi-scale topographical and orientation cues of the ECM for controlling cell structure and function. Using our platforms, the structures and orientations of fibroblast cells were greatly influenced by the nanotopography, rather than the micro-topography. We also proposed a new approach that enables the generation of native ECM having nanofibers in specific three-dimensional configurations by culturing fibroblast cells on the multi-scale substrata. We suggest that our methodology could be used as efficient strategies for the design and manipulation of various functional platforms for advanced regenerative medicine applications.

단청 문양을 활용한 아트 메이크업 작품 제작

김다운 한국메이크업디자인학회 2018 한국메이크업디자인학회지 Vol.14 No.2

The aim of this study is to add visual value to dancheong after analyzing its images and colors and applying them to art makeup to show that this colorful Korean-style decorative pattern is useful in art makeup. The results found that dancheong provides a motif for new art makeup styling, and that it is applicable to diverse makeup styles. However, it is hard to represent exact traditional colors because colors are matched by using a brush. Furthermore, it is difficult to vividly express the realism of dancheong along the line of the 3-dimensional curve of a human body. As makeup emerges as a genre of formative art, it is a time to explore a new design realm. Under these circumstances, dancheong-based art makeup can be a valuable inspiration and stimulate attempts at diverse styles. In order for dancheong to move more deeply and fully into art makeup, it would be necessary to accept the positive aspects and correct and improve the less usable areas.

An Empirical Study on the Relationship between Happiness and Fertility: A Country-level Analysis

김다운,김종섭 한국사회과학협의회 2023 Korean Social Science Journal Vol.50 No.2

Numerous studies have extensively examined the correlation between parenthood and individual happiness. However, the reciprocal relationship, wherein happiness influences a country’s fertility, has received little attention. This paper empirically tests whether countries with higher happiness levels exhibit correspondingly higher fertility rates in over 130 countries from 2005 to 2019 while controlling for the potential mediating factors such as income, education, etc. Through empirical analysis, this paper concludes that happiness is positively associated with fertility rates. Interestingly, when countries are stratified based on income levels, the relationship is not statistically significant for low-income and lower-middle-income countries but significant and positive for upper-income and high-income countries.

Rules for Scoring Respiratory Events in Sleep (2012 개정판)

김다운 대한임상병리사협회 2014 임상생리검사학회 발표자료집 Vol.2014 No.-

배경(Background) : 수면무호흡 또는 저호흡이 뇌혈관 질환, 심혈관 질환, 고혈압, 당뇨 등에 대한 위험성이 있다는 것은 이미 알려진 사실이다. 2012년 이전의 Respiration Rule은 대표적으로 Chicago Rule과 2007년 AASM Guide line에 의한 Rule이 있는데, 수면무호흡과 저호흡이 앞서 언급한 질환들의 위험성에 대하여 졸 더 유의한 지표로 활용될 수 있도록 많은 연구결과와 수면 전문가들에 의한 합의를 통해 좀더 명확하고 간결한 Rule로 개정되었다. 방법(Methods): 권고되는 측정장치는 oronasal thermal sensor. nasal air pressure transducer. pulse oximetry. Thoracoabdominal Belt. PAP device Flow 이다. 결과(Results) : Apnea Rule 은 다음 두 가지를 동시에 만족해야 한다; (1) There is a drop in the peak thermal sensor excursion by ≥90% of baseline. (2) The duration of the event lasts at least 10 seconds. 그리고 Hypopnea Rule은 다음 세 가지를 동시에 만족해야 한다; (1) The peak signal excursions drop by ≥30% of pre-event baseline using nasal pressure. (2) The duration of the ≥ 30% drop in signal excursion is ≥ 10 seconds. (3)There is a ≥ 3% oxygen desaturation from pre event baseline or the event Is associated with an arousal. 고찰(Discussion): 수면다원검사는 전 세계적으로 미국의 AASM Guide Line을 따르고 있다. 우리나라의 수면다윈검사실도 2012년에 개정된 Scoring Rule 을 알고 이해하는 것에 대한 필요성이 있겠다.