국내 Holstein종에서 milk β-hydroxybutyrate acid, milk acetone, 에너지 보정유량 및 산유량의 유전모수 추정

이석현,최성운,당창권,Alam Mahboob,도창희 한국데이터정보과학회 2017 한국데이터정보과학회지 Vol.28 No.6

This study was conducted to estimate the genetic parameters for common ketosis indicators (β-hydroxybutyrate acid, BHBA; milk acetone), feed intake efficiency indicator (energy-corrected milk, ECM), and milk yield (MY) in Korean Holstein. A total of 75,072 monthly test-day records from 14,397 first parity cows were collected, between 2012 and 2016, from Korea animal improvement association enrolled farms. Variance components were estimated using a multiple trait random regression model. The heritability of BHBA and acetone levels ranged from 0.06 to 0.15 at different DIMs. The phenotypic and genetic correlations between BHBA and acetone were between 0.73 and 0.90, and between 0.93 and 0.98, respectively. The phenotypic correlation between BHBA and MY, between acetone and MY, between BHBA and ECM, and between acetone and ECM ranged from -0.18 to -0.05, -0.23 to -0.05, 0 to 0.10, and -0.09 to 0.01, respectively. Genetic correlation estimates between BHBA and MY, between acetone and MY, between BHBA and ECM, and between acetone and ECM also ranged from -0.55 to 0.05, -0.62 to -0.04, -0.10 to 0.11, and -0.20 to 0.00, respectively. We hope that these results would greatly assist in the improvement of ketosis disease in the local Holsteins. 케토시스 질병의 지표 형질인 milk β-hydroxybutyrate acid (BHBA), milk acetone, 그리고 사 료효율의 지표형질 에너지보정유량 및 젖소의 주요 경제 형질인 산유량에 대한 유전력과 이들 간의 유전적 관계를 통하여 젖소의 케토시스 저항성 증진 가능성을 확인하기 위하여 본 연구를 수행하였다. 국내 젖소 14,397두에서 수집된 산유능력 검정자료 75,072건의 기록과 혈통기록 44,954두의 기록을 다형질 임의회귀 검정일 선형 모형을 이동하여 분석하였다. 케토시스 지표형질들의 유전력은 범위 0.06 - 0.15, 평균 0.08 (± 0.03)로 추정되었으며, 케토시스 지표형질들 간에 표현형 상관은 범위 0.73 - 0.90, 평균 0.78 (±0.04), 유전 상관은 0.93 - 0.98 평균은 0.97 (±0.01), milk BHBA, milk acetone과 산유량의 표현형 상관은 범위 -0.18 - -0.05 평균 -0.08 (±0.027), 범위 -0.05 - -0.23, 평 균 -0.1 (±0.041), 유전상관은 -0.55 - 0.05, 평균 -0.16 (±0.18), -0.62 - -0.04, 평균 -0.24 (±0.17)로 각각 주정이 되었다. milk BHBA, milk acetone과 ECM의 표현형 상관관계는 0.056 (±0.023), -0.04 (±0.029), 유전적 관계는 평균 0.023 (±0.08), 0.09 (±0.067)로 각각 추정되었다. 따라서 산유 능력 검정자료 수집 시 부가적으로 수집되는 케톤체를 이용하면 케토시스 저항성 증진을 할 수 있을 것으로 사료된다.

아세톤 누출사고 예방을 위한 아세톤 가스 조기감지 기술개발에 관한 연구

전승진,최영보 한국안전학회 2023 한국안전학회지 Vol.38 No.2

Acetone is a widely used Volatile Organic Compound (VOC) in industries and laboratories. However, acetone affects human health adversely and causes fires and explosions. Early acetone detection and improved personnel training in safety and emergency management are necessary to prevent acetone-related accidents. The multi-VOC acetone detectors used currently have a sensitivity and selectivity limit. In this study, we discovered that Pt-loaded iron oxide (a metal oxide semiconductor) conversely, has high detection and selectivity for very low-levels of acetone gas. The loaded Pt catalyzes the reaction between the sensing materials’ surface and the oxygen molecules in the air; this optimizes acetone detection and can decrease acetone-related illnesses, fires and explosions.

폴리쉬 리무버 반복시술에 따른 손톱의 물리적 성상과 형태학적 변화

이나리 ( Na Ri Lee ),송원길 ( Won Kil Song ),최은미 ( Un Mi Choi ),이현숙 ( Huyn Sook Lee ),김기영 ( Ki Young Kim ) 한국미용학회 2010 한국미용학회지 Vol.16 No.4

Nail products such as polish, polish remover and acrylates are widely used. And nail products have problems and risks of not only nail damage but also neurological abnormality, irritation of skin and mucous, reproductive disorder. So that, the aim of this study is to observe change of physical property and morphology on nail by treatment with nail removers. 5 women`s nails were collected and divided into 3 groups (non-treated, acetone remover treated, acetone free remover treated) and treated with two polish removers in one time, 3-times and 5-times. The thickness of transverse and roughness of surface were measured and observed after polish and polish remover treatment by hair diagnostic apparatus, SEM and AFM. The findings showed that the nails in the acetone-content polish remover group were significantly thin from 5.2±0.1 μm to 4.7±0.3 μm after 3-times of treatment and to 4.3±0.2 μm after 5-times of treatment (p<0.05), while those treated with acetone-free removers became also significantly thin from 5.1±0.1 μm to 4.9±0.1 μm after 3-times and to 4.6±0.1 μm after 5-times of treatment (p<0.05) in compared to non treated group. Observation with SEM from the morphological viewpoint, transverse and surface of the nails in the non-treated group featured relatively solid and high adhesion in the intermediate layer of keratine. After 3- and 5-times of treatment in repeatedly treated group. The aceton plish remover group with some scratches were found to be lysated and clotted and cuticles came off heavily from the transverse. In case of acetone-free remover group, however, a slight crack, clotting and crumbs appeared between layers after 3- and 5-time treatment and peeling off process of cuticles were slower compared to the case of acetone-content polish remover group by observation of SEM. The nails in acetone-content polish remover group was significantly increased in the roughness from 0.56±0.06 μm to 0.66±0.03 μm after 3-times treatment and to 0.78±0.02 μm after 5-times treatment (p<0.05), while the surface treated with acetone-free remover treated group was observed to have slightly increase of roughness from 0.56±0.06 μm to 0.58±0.11 μm after 3 times of treatment and to 0.61±0.02 μm after 5 times by AFM (p<0.05). These data suggested that acetone-free remover may be damaged to nails weaker than acetone-content remover.

Synthesis of Ce-doped In2O3 nanoparticles via a microwave-assisted hydrothermal pathway and their application as an ultrafast breath acetone sensor

유병훈,윤성도,나찬웅,윤지욱 한국표면공학회 2023 한국표면공학회지 Vol.56 No.6

Acetone, a metabolite detected from the exhaled breath of people doing a diet, can be used for non-invasive monitoring of diet efficiency. Thus, gas sensors with rapid response and recovery characteristics to acetone need to be developed. Herein, we report ultrafast acetone sensors using Ce-doped In2O3 nanoparticles prepared by the one-pot microwave-assisted hydrothermal method. The pure In2O3 sensor shows a high response and fast response time (τres = 6 s) upon exposure to 2 ppm acetone at 300 ℃, while exhibiting a relatively sluggish recovery speed (τrecov = 1129 s). When 20 wt% Ce is doped, the τrecov of the sensor significantly decreased to 45 s withholding the fast-responding characteristic (τres = 6 s). In addition, the acetone response (resistance ratio, S) of the sensor is as high as 5.8, sufficiently high to detect breath acetone. Moreover, the sensor shows similar acetone sensing characteristics even under a highly humid condition (relative humidity of 60%) in terms of τres (6 s), τrecov (47 s), and S (4.7), demonstrating its high potential in real applications. The excellent acetone sensing characteristics of Ce-doped In2O3 nanoparticles are discussed in terms of their size, composition, phase, and oxygen adsorption on the sensing surface.

FTIR Characterization of Acetone Fractionation of Industrial Softwood and Hardwood Kraft Lignin

( Ega Cyntia Watumlawar ),( Eko Setio Wibowo ),( Byung Dae Park ) 한국목재공학회 2022 한국목재공학회 학술발표논문집 Vol.2022 No.1

Lignin as the largest reservoir of aromatic polymer is being discarded as waste or burnt to recover heat and electricity even though it has a great potential as a feedstock of new bio-based wood adhesives. The structural complexity and heterogeneity of lignin is known as a limitation to convert it into value-added products. Hence, in this study, we prepared the homogeneous or reduced polydispersity Kraft lignin by one-step fractionation with acetone. The objective of this study is to investigate chemical characteristics of acetone-soluble and acetone-insoluble Kraft lignin from hardwood and softwood, using Fourier transform infrared (FTIR) spectroscopy. The results showed that 65% portion of hardwood Kraft lignin is dissolved in acetone while 35% remained insoluble. By contrast, 55% of softwood Kraft lignin is dissolved in acetone, whereas 45% is insoluble in acetone. Furthermore, FTIR results revealed the presence of aromatic skeletal vibrations of both hardwood and softwood Kraft lignin. As expected, syringil and guaiacyl bands were detected in hardwood Kraft lignin, whereas guaiacyl band was present only in softwood Kraft lignin. However, acetone-soluble and acetone-insoluble of Kraft lignin showed considerable different peaks.

저온, GA3, KNO3 및 Acetone 처리가 활나물 종자발아에 미치는 영향

강진호,김유진,전병삼 한국약용작물학회 2001 한국약용작물학회지 Vol.9 No.2

생약재로 이용되고 있는 활나물은 항암효과가 밝혀져 그 이용이 기대되나 종자발아가 불량하여 재배가 어려운 식물이다. 따라서 GA3, 저온, KNO3, acetone처리가 활나물의 종자발아에 미치는 영향을 구명하여 앞으로의 재배연구의 기초자료를 얻고자 본 연구를 실시하였던 바 그 결과를 다음과 같다. 1. 활나물 종자의 발아율은 GA3 처리시에는 0.1 mM에 12시간 암상태에서, 저온처리시에는 3℃에서 1주간 처리하는것에서 가장 높았다. 2. 발아율은 KNO3 처리시에는 400 mM에 6시간, acetone 처리시에는 200 mM에 6시간 처리하는 것에서 가장 높았으며, 이들 처리결과가 GA3 또는 저온처리의 최적결과보다 양호하였다. 3. 포장출현율은 200 mM의 acetone 용액에 6시간 처리하는 것보다 400 mM의 KNO3에 6시간 처리하는 것에서 높은 것으로 조사되어 활나물 종자처리는 KNO3를 이용하여 암상태에서 처리하는 것이 바람직한 처리방법으로 평가되었다. Crotalaria sessiflora is one of a few medicinal herbs among the legumes used as antitumor herb medicine but has lower seed germination and afterward seedling emergence. This study was carried out to elucidate the effects of cold stratification as presown treatment as well as GA3, KNO3 and acetone on its seed germination and seedling emergence. Cold stratification, GA3, KNO3 and acetone treatments were performed with different concentrations and period levels. Cold treatment was done under 14 hour red light illumination a day or darkness and the two others under darkness. On the basis of the best germination rate of each treatment, GA3 and cold stratification treatments showed the highest germination rates at 0.1 mM but 12 hours and 2 week periods under darkness, respectively. KNO3 and acetone treatments came out at 400 mM and 200 mM lasted for, respectively. The best germination rates from KNO3 and acetone were comparatively higher than those from the former GA3 and cold treatments. In evaluation of seedling emergence using the last two treatments, KNO3 treated seeds were better performed than acetone treated seeds showed somewhat higher germination rate, implying that presown seed treatments must be evaluated by the combination with indoor and field tests.

아세톤이 마우스 피부 조직의 ROS에 미치는 영향

최혜정(Hye-Jung Choi),이상희(Sang-Hee Lee) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.2

Acetone is one of the organic solvents that causes skin barrier disruption such as eczema and dermatitis, ichthyosis and xerosis, and ROS (reactive oxygen species) paly a role of skin toxicity. This study is focused on investigating the effect of ROS of applied acetone. Acetone was applied to mice skin (0.25ml/㎠) four times (6h, 12h, 18h, 24h) every day for two or four days. Increased activity of acid phosphatase (ACP) and increased content of lipid peroxide (LPO) in acetone was determined in the applied group for four days(4ACE) compared with the acetone applied group for two days (2ACE). As for the ROS generating enzymes, one of them, xanthine oxidase (XO) showed no differences between control and 2ACE despite the significantly different 4ACE. There were some differences between 2ACE and 4ACE on the activities of cytochrome P450 dependent aniline hydroxylase (CYPdAH), which seemed to be the increased rates of acetone metabolites. There were more decreased rates of the activities of ROS scavenging enzymes, glutathione peroxidase (GPx), catalase (CAT), superoxide dismutae (SOD), glutathione S-transferase (GST), and glutathione (GSH) contents in 4ACE compared with 2ACE. The results indicate that the damaged skin tissue could cause unbalance of the ROS generating system and scavenging system by the frequent exposure of acetone application.

폴리이서설폰 중공사막의 제조 및 O2/N2 투과특성

박성률,장봉준,안효성,김동권,김정훈 한국막학회 2011 멤브레인 Vol.21 No.1

공기 중 산소의 분압이 높아지면 불연성인 질소의 감소로 높은 열효율을 낼 수 있으며, 고농도의 질소는 LNG선의 방폭기체 및 청과류의 신선도를 유지하는데 이용되므로 효율적인 공기 중의 산소/질소 분리 공정은 매우 중요하다. 분리막은 적은 에너지 소모로 산소와 질소를 동시에 분리 농축시킬 수 있다. 본 연구에서는 막 재료로 폴리이서설폰을, 방사용매로 NMP를 그리고 첨가제로는 비용매이면서 PES를 잘 팽윤시키는 Acetone을 사용하였다. 방사용액을 아세톤의 첨가량의 변화에 따라 0, 6.5, 15, 25, 31.5% (wt%)로 조절하여 제조하였고, 각 방사용액을 0~10 cm의 방사높이 변화에 따라 방사하였다. 제조된 중공사막은 실리콘을 코팅하여 산소 및 질소의 선택도 및 투과도를 코팅전후와 비교하여 조사하였다. Acetone의 함량 변화에 크게 관계없이 방사높이가 증가할수록 투과도는 감소하고 선택도는 증가하였다. 연신방법을 이용하여 방사한 결과 자유낙하(free fall)로 방사한 중공사막에 비해 선택도는 약간 감소하였지만 투과도는 증가하는 것으로 나타났다. 최적의 중공사막은 폴리이서설폰 37 wt%, Acetone 6.5 wt% NMP 56.5 wt%의 용액을 사용하였고, 실리콘 코팅 후에 외경 320mum 7.3의 O2/N2 선택도 및 산소투과도 4.3 GPU의 우수한 성능을 나타내었다. Highly enriched oxygen is used in energy-efficient combustion due to decreased non-flammable nitrogen, while high purity nitrogen is used for explosion proof in the LNG ships and keeping the freshness of green stuffs. Membrane technology can be used in these O2 and N2 generation with low energy consumption. In this study, PES was used as a membrane material and 1-methyl-2-pyrollidone (NMP) and acetone were employed as a good solvent and nonsolvent addictive (swelling agent to PES), respectively. Dope solutions were prepared by changing the content of acetone (0, 6.5, 15, 25, 31.5 wt%) in 37 wt% PES solutions. Hollow fiber spinning was performed at 0~10 cm of air-gap distances for each dope solution. O2/N2 selectivity and permeability were investigated by comparing of hollow fibers coated or not by silicons. O2/N2 selectivity increased and permeance of O2 and N2 decreased with increasing air-gap height independently of acetone addictions. Optimized PES hollow fibers were obtained with 37/6.5/56.5 wt% PES/acetone/NMP dope solution and 10 cm air-gap, which showed 7.3 of O2/N2 selectivity and 4.3 GPU of O2 permeability after silicon coating.

Development of an Acetone/water Fractional Precipitation Process for Purification of Paclitaxel from Plant Cell Cultures

김태완,김진현 한국생물공학회 2016 Biotechnology and Bioprocess Engineering Vol.21 No.6

This study investigated the efficiency of acetone/water fractional precipitation for the purification of paclitaxel from plant cell cultures. Adding distilled water at room temperature into an acetone solution of dissolved crude extract until the acetone/water ratio became 40:60, 30:70, 20:80, and 10:90 (v/v) and stirring the mixture for 10 min at room temperature resulted in paclitaxel yields of 54.3, 89.1, 95.5, and 97.6%, respectively. With an acetone/ water ratio of 40:60, v/v, a high yield of paclitaxel (84.8 ~ 86.0%) was produced by an additional 2 h storage at a low temperature (4oC) without additional mixing, or at room temperature with additional mixing. In contrast, preparing the 40:60 (v/v) acetone/water mixture at a low temperature (4oC) and mixing for 10 min at a low temperature, a similar high yield (~ 87.9%) of paclitaxel was obtained immediately. Thus, increasing the proportion of distilled water, or decreasing the temperature of the added water were confirmed as important for obtaining high yields of paclitaxel by acetone/water fractional precipitation.

Comparison of Breakthrough Characteristics for Binary Vapors Composed of Acetone and Toluene Based on Adsorption Intensity in Activated Carbon Fixed-bed Reactor

이민규,이송우,감상규 한국공업화학회 2007 Journal of Industrial and Engineering Chemistry Vol.13 No.6

This study was carried out to investigate the adsorption intensity between adsorbates and activated carbon in the binary vapor system of acetone-toluene mixed vapor. Breakthrough curves were compared according to adsorption intensity by breakthrough experiments. The breakthrough curve of toluene vapor in the binary vapor system was similar type to that of single vapor, but the breakthrough curve of acetone vapor was quite different from that of single vapor because of difference of adsorption intensity between adsorbates and surface of activated carbon. In these binary vapor systems, the roll-up phenomenon was observed. When acetone concentration was increased to twice in the binary vapor system, the breakthrough curve of toluene was similar to before but the height of roll-up of acetone was increased to 1.5 times than before. When toluene concentration was increased to twice, the breakthrough curve of toluene was different from before and the height of roll-up of acetone was acetone increased to 1.65 times than before. As increasing linear velocity, the slopes of breakthrough curves were increased and the height of roll-up of acetone increased to 2.3 times than inlet concentration.