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      • MMPI의 긍정왜곡 반응에 관한 연구

        김연,정숙회 인제대학교 1994 仁濟醫學 Vol.15 No.2

        본 연구는 정상인 집단과 정신분열증 환자집단의 MMPI 반응에서 긍정왜곡에 관한 차이를 알아보기 위한 것으로 329명의 정상군과 110명의 정신분열증 환자군의 MMPI의 결과를 비교하였다. 정상군과 정신분열증 환자군의 긍정왜곡 반응은 통계적으로 유의한 차이를 보이지 않았다. The present study attempted to detect the difference between the normal group and schizophrenic patient group, in faking-good attitude in MMPI responses. Four hundred thirty none subjects were selected and administered the MMPI. The results of 329 normal group were compared to 110 schizophrenic patients. The result reveals the normal group did more faking-good than the schizophrenic group but not significant statistically. On the other hand when L equals or excells 9, K equals or excells 17 and F-K is less than -11, the two groups showed a great difference among the clinical scales, that is, the scale of psychopathic deviates at the significant level P<.05, the scales of psychasthenia, schizophrenia and social introversion at the significant level P<.001. It is recommended that the clinical scales should be used in diagnosing neuropsychiatric diseases.

      • 초음파 주파수와 음향밀도에 따른 하수슬러지 전처리 특성

        김대용,정연화,김한석,정진희,성낙창 東亞大學校 建設技術硏究所 2008 硏究論文集 Vol.31 No.2

        The objective of this study was to investigated the pretreatment characteristics of sewage sludge by ultrasonic process. Excess sewage sludge was sampled from N sewage treatment plant (STP) in B city. The ultrasonic processor was designed to operate with 28 kHz and 40 kHz,independently. During sonication experiment, sludge samples were stirred by agitator. The acoustic densities were changed 33 to 139 W/L by control of current strength. The sonication time was in the range of 10 min and 40 min. The total chemical oxygen demand (TCOD) and soluble chemical oxygen demand (SCOD) of sludge were analyzed with K2Cr207 Closed Reflux Method. The results showed that sonication with 28 kHz of acoustic frequency is better than sonication of 40 kHz in incensement of SCOD/TCOD ratio. Also, the sludge solubilization rates increased as the sonication time and acoustic density increased. The application of dual frequency sonication for sludge pretreatment can be interest for sewage treatment plants having problems in sludge treatment and disposal.

      • 국내 가사노동 연구의 동향 분석 (I) : 생활시간, 태도 및 만족도, 가사분담 연구를 중심으로 with focus on the literatures of the time studies, the attiudes toward and satisfaction with household tasks, and the division of household tasks

        김대년,이연숙 카톨릭 대학교 생활과학 연구소 1990 생활과학연구논집 Vol.10 No.1

        The purposes of this study are to analyze the trends of household task studies and to identify the common variables affecting each topic. The results of review of the literature were as follows: ①The variables affecting the attitudes toward, value perception about and satisfaction with the household tasks were the education level and age of wife, income, employment status of wife, and length of marriage. The psychological factors were found to be the variables affecting the level of satisfaction with household tasks. ②The age of children, employment status of wife, income, and the presense of house keeper were found to be as factors affecting the amount of time spenton household tasks. ③Compared with other studies, the variables affecting the aspects of household task division were found not to differ among studies. The impacting variables were the employment status of wife, the age of wife, socio-economic status of the family, structure of house, and income.

      • KCI등재후보

        일 대학 병원 마취 · 회복실 간호사의 간호활동 분석

        강윤경,김경미,김연이,박혜옥,서광희,송숙녀,이현숙,조의영 대한간호행정학회 2006 간호행정학회지 Vol.12 No.1

        Purpose: This study was aimed to specify roles of nurses from the anesthesia and recovery room by analyzing nursing activities as well as anesthesia nursing during surgery. Method: The objects were 12 RNs working in the recovery room of a university hospital located in Incheon. Self-report was performed by measuring stop-watch for five days from May 17th to May 21st in 2004. Research method was designed to record the time and frequency of the nursing activity from anesthesia and recovery room based on nurses' statement and other references for five days. The data were analyzed with descriptive statistics, ANOVA, and t-test via SPSS Win 10.0 program. Result: Nursing activities in anesthesia recovery room were classified into two different characteristics such as direct and indirect nursing activity. The activities consisted of 11 direct nursing areas and 39 nursing activities in anesthesia preparation room. The indirect nursing was classified into 8 nursing areas and 32 nursing activities. The direct nursing was classified into 12 nursing areas and 55 nursing activity. Also, the indirect nursing was classified into 7 nursing areas and 21 nursing activities in recovery room. In terms of prevalence of nursing activities in the anesthesia preparation room, observation and cooperation of anesthesia was the most prevalent activity, drug and eqipment management the second prevalent, and drug administration the third. On the other hand, in the recovery room, the most prevalent activity was vital sign checking and observation, the second most prevalent activity informative activity, and the third body temperature control. Nursing activity time was recorded according to the nursing characteristics. In the anesthesia preparation room, the direct nursing spent for 8092.20 minutes was larger than the indirect nursing spent for 7198.50 minutes. Also, in the recovery room, the direct nursing spent for 2361.16 minutes was larger than the indirect nursing spent for 1134.13 minutes. 4. Nursing activity time was compared to duty shifts. In the anesthesia preparation room, the direct nursing was more prevalent on day shift and the indirect nursing was prevalent on evening shift. However, in the recovery room, both direct and indirect nursing activities were prevalent on day shift. Conclusion: The role of anesthesia and recovery room nurses was analysed according to the time, frequency, and its characteristics.

      • Carboxymethyl chitosan의 항균성과 항곰팡이성

        선우양일,박현숙,탁연수,최윤정,김광 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.1

        Chitin was converted to chitosan by deacetylation, and then carboxymethyl chitosan(CM-chitosan)was obtained by carboxymethlation of chitosan. The antibacterial activity was estimated using the miminum inhibitory concentration (MICwt%) assay. MICwt% of Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, candida albican and Staphylococcus aureus were 0.5, 0.5, 0.25, 0.25, 0.75 respectively. CM-chitosan was tested for antifungal antivity which is measured the inhibition of hyphal extension of the fungi. MIC_(50)wt% of CM-chitosan was shown half growth of the experimental over control group. MIC_(50)wt% of Penicillium citrinum, Myrothecium verrucaria and Verticillium albo-atrum were 0.5, and Gliocladium virens was 0.75, respectively. These results showed that CM-chitosan had the high inhibitory effect on the growth of the bacteria and fungi.

      • 수술적으로 치료한 통증을 동반한 흉추부의 후외상성 Schmorl씨 결절 : 2례 보고 Report of Two Cases

        신병준,이재철,송화용,정석봉,권계원,조영일,김연일 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Study Design : Two patients who had painful Schmorl's node at thoracic level from acute trauma were adopted and taken operation for its treatment Objectives : To document the effect of operation for the treatment of painful Schmorl's node at thoracic level summary of background data : Schrmorl's nodes are common spinal lesion generally believed to be asymptomatic, but in some cases there were painful symptom by Schmorl's node. This case report is to explain the effect of operative treatment for the painful Schmorl's node. Methods : Two patients were adopted who had traumatic painful Schmorl's node at thoracic level for our case report. They were treated conservative methods at first but it's effect were poor, so they were taken anterior decompression and fusion, and checked back pain symptom. Result : In all two patients, the symptom of back pain by Schmorl's nodes at thoracic level was almost subsided. conclusion : For the treatment of traumatic painful Schmorl's node, most of surgeon says that conservative treatments were treatment of choice, but operative treatments are also benefit to subsidence of back pain by Schmorl's node.

      • Taxol-Induced Apoptosis and Nuclear Translocation of Mitogen-Activated Protein (MAP) Kinase in HeLa Cells

        Kim, Sung-Su,Kim, Yoon-Suk,Jung, Yon-Woo,Choi, Hyun-Il,Shim, Moon-Jeong,Kim, Tae-Ue Korean Society for Biochemistry and Molecular Biol 1999 Journal of biochemistry and molecular biology Vol.32 No.4

        Taxol, a natural product with significant anti-tumor activity, stabilizes microtubules and arrests cells in the G2/M phase of the cell cycle. It has been reported that taxol has additional effects on the cell such as an increase in tyrosine phosphorylation of proteins and activation of mitogen-activated protein (MAP) kinase. This phosphorylated kinase translocates into the nucleus and phosphorylates its substrate c-jun, c-fos, ATF2, and ATF3. The MAP kinase family is comprised of key regulatory proteins that control the cellular response to both proliferation and stress signals. First examination was cytotoxicity and apoptosis-induced concentration with paclitaxel in HeLa cell. A half-maximal inhibition of cell proliferation ($IC_{50}$) occurred at 13 nM paclitaxel. When DNA fragmentation was analyzed by agarose gel electrophoresis, a nucleosomal ladder became evident 24 h after a taxol (50 nM) addition to the cells. In addition, an apoptotic body was detected by electron microscopy. Taxol-treated cells were arrested at the S phase at 10 nM. Treatment of 50 nM taxol activated the extracellular signal-regulated protein kinase (ERK1), and a fraction of the activated MAP kinases entered the nucleus. It was also discovered that nucleus substrates c-jun was phosphorylated and activated in the cell. The activated ERK1 could subsequently translocate into the nucleus and phosphorylate its substrate c-jun as well. This study suggests that taxol-induced apoptosis might be related with signal transduction via MAP kinases.

      • SCIESCOPUSKCI등재

        n-butanol Fraction of Uncaria rhynchophylla Induces Apoptosis in Human Hepatoma Cancer Cells through Activation of PARP

        Kim, Yon-Suk,Hwang, Jin-Woo,Kwon, Hyuck-Ju,Lee, Won-Young,Song, Hyuk,Jeong, Jae-Hyun,Sung, Si-Heung,Moon, Sang-Ho,Jeon, Byong-Tae,Park, Pyo-Jam 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.3

        The ability of water and ethanolic extracts isolated of Uncaria rhynchophylla (UR) to function as an anticancer agents was studied using HepG2 cells. The ethanolic UR extract was further fractionatedwith hexane, chloroform (CHCl3), ethyl acetate (EtOAc), n-butanol (n-BuOH), and water, and these fractions were subsequently investigated for anticancer activity. Among the fractions, the n-BuOH fraction induced apoptosis in a dose- and time-dependent manner, when determined by cell cycle analysis, Annexin V-FITC/PI double staining, and Hoechst 33342 staining. Moreover, the n-BuOH fraction induced apoptotic cell death by modulating the expression of caspase-7, caspase-8, and poly ADP ribose polymerase (PARP). These results indicated that the n-BuOH fraction from UR has strong anticancer activity in HepG2 cells and causes an upregulation of apoptotic proteins through the activation of PARP.

      • KCI등재후보

        민물에서의 가익사후 발생한 급성 신부전 1예

        김성래,김석영,이영재,김태연,문건웅,윤성노,이종민,안석주,방병기,서광선 대한내과학회 1997 대한내과학회지 Vol.53 No.3S

        저자들은 민물에 빠진후 4일간의 오심, 구토를 동반한 복통을 주소로 내원한 22세 남자 환자에서 조직 검사상 허혈성 급성 신부전으로 증명된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A number of complications may arise in patients who survive episodes of near-drowing. After aspiration of fresh water, extensive hemolysis, anoxia and hypotension occur, and may predispose a patient to the development of acute tubular necrosis, which is a recognized complication of near drowning in fresh water. A 22-year-old man was admitted to hospital with abdominal pain for 4 days following an episode in which near drowning while swiming in the river. We determined that he was in acute renal failure. The renal biopsy revealed acute tubular necrosis (ATN) and we suspected that the cause of ATN was hypoxemia. To our knowledge, this is first report of ATN by near drowning in Korea. We report the case and the review of the literature.

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