백혈병환자에서 Liposomal Amphotericin B로 치료된 파종성 Fusarium 감염 1예

이지연,김성범,박대원,신성희,김용현,윤소영,엄중식,최철원,정희진,김우주,김준석,김장수,이갑노 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

Fusarium spp.는 사람에서 드물게 각막염, 조갑진균증, 상처나 화상부위감염 등을 유발하는 것으로 알려져 있으나 최근에는 면역저하자에서 기회감염의 원인균으로 증가하고 있는 추세이다. 면역저하자에서 파종성 감염이 있는 경우에 예후는 치명적이나, 증례가 많지 않고 진단방법이 제한되어 있어 조기 진단과 신속한 치료가 쉽지 않다. 그러나 특징적으로 피부병변의 동반이 흔하여 면역저하자에서는 피부 병변의 면밀한 관찰과 함께 Fusarium 감염을 조기에 의심하여 피부생검이나 배양을 하는 것이 진단에 도움이 되리라 생각된다. 파종성 Fusarium 감염의 치료로는 감염 부위의 국소적 외과적 절제와 전신적 항진균제의 사용이 필요하고 현재까지는 amphotericin B가 비교적 효율적인 항진균제로 알려져 있으나 면역저하자에서 이에 반응을 하지 않는 경우가 많다. 저자들은 급성골수성백혈병 환자에서 관해유도화학요법 시행 후 호중구감소상태에서 피부병변과 폐침윤이 발견되었고 피부의 중심부 궤양을 동반한 구진성 병변에서 배양검사를 통해 파종성 Fusarium 감염을 진단하였으며 liposomal amphotericin B (AmBisome )를 사용하여 성공적으로 치료한 예를 경험하여 보고하는 바이다. Fusarium spp., basically a superficial pathogen, is a newly emerging fungal pathogen of opportunistic infections in immunocompromised patients. At present, although Fusarium spp. are relatively resistant to amphotericin B, the combination of amphotericin B and surgical debridement appear to be optimal treatment for disseminated infection. Recently we experienced a 32-year-old neutropenic patient after induction chemotherapy for acute myelocytic leukemia presented with skin lesions and infiltrations in both lungs. We diagnosed with disseminated fusariosis by skin culture and successfully treated the patient with liposomal amphotericin B. We emphasize a high index of suspicion for skin lesions especially in immunocopromised patients.

직접강도법에 의한 축대칭 원추형 쉘의 단순화 해석

김우중,권중현,이관희 진주산업대학교 1997 論文集 Vol.36 No.-

The stress analysis concerned with axisymmetrically loaded axisymmetrical structures, such as pressure vessels, rockets, cooling towers, roof domes and storage tanks, has been researched with a lot of difficulties. The elements of revolution using the finite element method enable these problems to be analyzed with a high degree of confidence. This research focuses on the efficient conduct of the thin axisymmetric shells subject to axisymmetrical load which was idealized by a series of conical frustum-shaped elements that was suggested by Grafton and Strome and later extended by Percy. In this study, this research mentioned above is extended to the conical shell whose end is fixed to simplify the methodology of the analysis of any kinds of axisymmetrically loaded axisymmetrical shell structures. To demonstrate the validity and simplicity, the results of the proposed method were compared with the numerical solution SAP90 and got agreeable results.

역순사전의 효용성

金祐重 대구효성가톨릭대학교 외국어문학연구소 1990 語文學硏究 Vol.3 No.-

건축법 개정의 변천에 관한 연구 : 규모, 형태 및 도시경관의 규정을 중심으로 in Case of the Control of Shape, Bulk and Landscape

김영창,이응희,이중우 대한건축학회 2003 대한건축학회논문집 Vol.19 No.3

The purpose of this study is to analyze the amending contents of the existing Building Codes(BC) from 1962 to 1999, on the basis of forming and its variation of building space, and then finds their relations and characters. This study consists of three parts : shape control, bulk control and landscape. As Korean indigenous social development has led the BC where it stands now, the shape of BC cannot be understood independently from the citizens attitudes level towards law and quality of life. Nation's cultural background do not seems to play key roles in the making and implementation of the BC. Especially Yin Yang Non do not manage to prevail in the course of implementation. The amendments of BC is perfected only on the current problem, not interrelation of current and ideal fact.

콘크리트 온도변화 특성에 관한 실험적 연구

김우중,이원홍,이관희 진주산업대학교 1999 산업과학기술연구소보 Vol.- No.6

Generally, concrete temperature is risen by hydration at mixture right after, after that falling gradually until the atmospheric temperature. For this temperature falling concrete is contracted. If contraction is restricted externally of internally tensile stress is occurred at concrete. If this tensile stress exceeds tensile strength of concrete tensile crack is occurred at concrete. The rahmen bridge among many bridge type is typical type that is occurred tensile crack at slab. In this paper, the authors investigate how temperature of a rahmen concrete bridge is changed by slab position and the number of days. The experimental results will be applied important crack control data by hydration at concrete.

Fly Ash를 사용한 수중 불분리 콘크리트의 배합 방법에 따른 콘크리트의 성질에 관한 연구

김우중,권중현 진주산업대학교 1997 論文集 Vol.36 No.-

This study investigates the effect of mixing method on the antiwashout underwater concrete containing Fly Ash. On the experimental condition, the unit weight of used materials was fixed and a new the mixing method different from the traditional method in its prolonged mixing time and the order of material inputs was used. In this experiment, the mixing time was prolonged to 10 minutes, and the order of material input was changed to make the admixture homogeneous. That method of mixing improved the fluidty, the unit weight and compressive strength of fresh concrete.

고리해역에서의 해수유동에 관한 연구

김재중,현우성 東亞大學校 海洋資源硏究所 2002 硏究論文集 Vol.14 No.1

The flow patterns in the Gori area was studied to find the characteristics of warm water diffusion and the radioactive materials dispersion. Fiend measurements were carried out for one year(1998.11-1999.8) and current velocity and direction, water temperature, salinity data were achieve in this field measurements. The numerical simulations were also carried out by using depth-averaged 2-D flow model.The calculated data were compared with measured data and the results show farely good agreement.

유니사이클 로봇에 대한 인간적 추론 제어 메카니즘

김중완,안찬우,전태옥,전언찬,정희균 동아대학교 공과대학부설 생산기술연구소 1996 生産技術硏究所硏究論文集 Vol.1 No.2

Our unicycle has simple mechanical structure.But unicycle's dynamical system is a very sensitive unstable nonlinear system. equations of motion for a simple unicycle robot were derived using Lagrage's method. In this paper, a human fuzzy influence control mechanism was established throught an inquiry into human riding a unicycle, and we developed a hybrid controller to control our unicycle robot. This proposed hybrid controller is consisted with a pure PD and two fuzzy gain scheduled controllers and a direct fuzzy logic controller. Computer simulation results show that our hybrid controller has robust control performnance to unstable nnonlinear unicycle robot system.

한국 대학의 국제화 교육 방안 : 사례 연구 및 국제화 전략 모형 Case Study and Internationalizing Modeling

金祐重 대구효성가톨릭대학교 외국어문학연구소 1993 語文學硏究 Vol.6 No.-

자원봉사자들의 탈북자 지원 경험 분석 : 설문결과를 중심으로

강성록,김형중,윤덕룡,전우택,민성길 연세대학교 통일연구원 2001 통일연구 Vol.5 No.1

Objectives: Since 1994, the number of North Korean defectors, escaping North Korea and entering South Korea, has in creased rapidly.The Government has provided most of te support for the defectors' adaptation to their new society.But as the number of defectors has increased, and the support needs have become more various, the support of volunteers from non-governmental organization(NGO) has become very important.To raise the level of the success and effectiveness of the support from the volunteers, their experiences were surveyed and analyzed. Methods: This study surveyed 83 volunteers of 7 NGOs involved in helping North Korean defectors' adaptation to South Korean society-48 men and 34 women. Results: In their relationships with defectors, women volunteers have more difficulties in their first 3 months.However volunteers in their 50s and 60s tend to have more stable and better relationships with defectors than younger volunteers.Many volunteers statedexperiences of human difficulties with defectors, for example, mistrust and anxiety in human relationship (n=34, 41.0%), psychological maladjustment(n=19, 22.9%), different ways of thinking and culture(n=17, 20.5%), economic difficulties(n=10, 12.0%), and lack of independence spirit(n=6, 7.2%).The volunteers said they have feelings of goddwill toward defectors when defectors showed warm heart(n=30, 36.1%), politeness(n=30, 36.1%), positive and active character (n=24, 28.9%), strong will(n=17, 20.5%), and plainness (n=14, 16.0%).The volunteers stated an absence of goodwill feelings to defectors when defectors showed uncompromising and aggressive attitudes (n=29, 34.9%), lack of independent will (n=28, 33.7%), selfishness (n=18, 21.7%), and avoidance of making human relationship (n=16, 19.3%).as for adequate training before commencing activity, 5 volunteers(6.0%) said they had received enough education before their activity, 31(37.3%) relatively enough, 38 (45.8%) relatively not enough, and 9 (10.8%) absolutely not enough education.If they were the owners of al company, 27 volunteers (51.9%) sanid they would want to thire defectors even if the defectors did not have the required ability. Conclusion: These results showed that NGO's volunteers have a friendlier attitude to defectors than policemen n charge and public officials, which is their strong point.Women volunteers experience more difficulties in their early relationships with defectors, suggesting the need for a specific pre-education program for women volunteers.Furthermore, NGOs would benefit from an increase in the number of volunteers in their 50's and 60's.Both volunteers and defectors need to understand each othe to a deeprer extent and the characteristics to which South Korean volunteers feel goodwill need to be used n their education.