[뉴스 부문 제112회 이달의 방송기자상] 다스는 누구 겁니까?

김준석 (사)방송기자연합회 2018 방송기자 Vol.41 No.-

암반사면 붕괴조사를 통한 사면기울기 결정사례연구

김준석 한국재난정보학회 2022 한국재난정보학회 학술대회 Vol.2022 No.10

조혈모세포이식시 발생한 급성 비감염성 합병증

김준석,김병수,서재홍,김열홍,신상원,최철원 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.1

연구배경 : 조혈모세포이식시 발생하는 급성 비감염성 합병증이라 함은 고용량의 항암화학요법으로 인한 독성과 채집된 조혈모세포가 포함된 혈액을 중심정맥을 통하여 주사할 때 발생하는 부작용 및 이식된 조혈모세포가 골수에 생착하여 조혈기능이 정상화되기까지의 시기에 발생하는 감염을 제외한 모든 합병증을 말한다. 저자 등은 고려대 의료원 혈액종양내과에 내원하여 조혈모세포이식을 시행받은 환자들에서 발생한 급성 비감염성 합병증의 양상을 보고하고자 한다. 방법 : 1995년 1월부터 1997년 12월까지 고려대 의료원 혈액종양내과에 입원하여 조혈모세포이식을 시행받은 45명(구로병원; 36명, 안암병원; 9명)을 대상으로 하였다. 이 중 동종 골수이식은 17명 , 자가 조혈모세포이식은 28명이 시행받았다, 저자 등은 조혈모세포이식을 시행받은 환자들의 급성 합병증으로 항암요법과 관련된 비혈액학적 독성(WHO기준), 조혈모세포가 포함된 혈액의 주사와 관련된 부작용, 골수생착시기에 발생한 비감염성 합병증으로 나누어 분석하였다. 결과 : 1) 고용량 항암요법과 관련된 비혈액학적 독성 ; 자각증상으로는 오심 및 구토가 전례에서 발생하였으며 46.7%(21/45)에서는 gradeⅢ이상으로 심하였으며 이학적 소견으로는 점막염이 89%(40/45)로 가장 흔히 발견되었다. 기타, 간독성이 11.1%(5/45), 신독성이 6.7%(3/45)에서 관찰되었다. 고용량 항암요법과 관련된 치명적인 비혈액학적 독성(간의 정맥폐쇄증후군, cytoxan에 의한 심근독성)으로 4.4%(2/45)에서 사망하였다. 2) 조혈모세포가 포함된 혈액의 주사와 관련된 부작용 : 동종 골수 이식시 환자의 중심정맥을 통하여 이식된 조혈모세포가 포함된 혈액의 주사와 관련된 부작용은 매우 경미하였다. 자가 조혈모 세포이식시 말초혈에서 혈액성분 분리기를 통하여 채집한 후 냉동보호제인 DMSO와 10%의 농도로 혼합하여 냉동보존(-80∼-180℃)한 조혈모세포가 포함된 혈액을 40℃수조에서 해동한 후 환자의 중심정맥을 통하여 이식하였다. 그 결과 평균 용적이 커서 DMSO가 보다 많이 포함된 조혈모세포가 포함된 혈액을 이식받는 환자들에서 오심, 열감 및 오한, 구토, 혈뇨 등의 합병증이 호발하였다는 사실을 알 수 있었다. 3) 골수 생착시기에 발생한 비감염성 합병증 : 동종 솔수이식 환자에서 골수생착시기에 해당하는 무균실 입원기간 중에 발생한 비감염성 합병증으로 급성 이식편대 숙주반응이 25%에서 발생하였으며 생착실패가 6.7%에서 관찰되었다. 급성 이식편대 숙주반응은 모두 grade Ⅰ,Ⅱ로 경미하였으며 생착실패를 보인 환자는 이식70일 만에 기존 백혈병이 재발되어 사망하였다. 자가 조혈모세포이식 환자에서는 3예에서 자연생착이 관찰되었다. 결론 : 조혈모세포이식시 비감염성 급성 합병증으로 발생하는 항암요법과 관련된 독성, 조혈모세포가 포함된 혈액의 주사와 관련된 합병증, 골수생착기에 발생한 비감염성 합병증들은 빈도가 낮고 경하지만 치명적인 경우도 있었다. Background : The purpose of this study was to evaluate the acute non-infectious complications of hematopoietic stem cell transplantation, at the patients admitted to hemato-oncology department, Korea University Medical Center, from January, 1995 to September 1997. Methods : Forty-five patients (17 allogeneic bone marrow transplantation, 28 autologous hematopoietic stem cell transplantation) were evaluated for the incidence and severity of the acute non-infectious complications associated with hematopoietic stem cell transplantation, such as regimen related toxicities, transfusion reactions of blood containing hematopoietic stem cells, complications associated whit engraftment. Results : 1)Regimen-related toxicities : The patients complained the symptoms of nausea, vomiting, anorexia, diarrhea, fatigue, myalgia, arthralgia, sore throat, and febrile sensation. Mucositis was most frequently observed regimen related toxicity with the incidence of 89%(40/45). The other regimen related toxicities were liver toxicity (11.1%, 5/45) and renal toxicity (6.7%, 3/45). The fatal regimen related toxicities such as veno-occlussive disease and cardiomyopathy, were observed at two patients. 2) Transfusion reactions of blood containing hematopoietic stem cells : At allogeneic bone marrow transplantation, the transfusion of RBC depleted bone marrow blood were tolerable at all patients with minimal side reactions. At autologous hematopoietic stem cell transplantation, the side reactions such as nausea and vomiting (85.7%) febrile sensation(78.6%), abdominal pain(28.6%), hematuria (28.6%), dyspnea (14.3%), seizure (7.1%), and sudden death(3.6%), were observed during the transfusion of thawed blood containing hematopoietic stem cells mixed with DMSO for cryopreservation. The incidence and severity of side reactions were assocaited with the transfusion volume and DMSO amount. 3) Complications associated with engraftment : Graft failure associated with leukemia relapse was observed at 1 case of allogeneic bone marrow transplantation, and three patients, transplanted with autologous hematopoietic stem cells, experienced delayed engraftments. The incidence of acute GVHD in allogeneic bone marrow transplantation was 25%(grade Ⅰ,Ⅱ). All patients with acute GVHD were successfully treated by cyclosporin A, methotrexate, steroid therapy. Conclusion : The acute non-infectious complications of hematopoietic stem cell transplantation occured infrequently, and the severity was mild. But, fatal outcomes associated with acute non-infections complications of hematopoietic stem cell transplantation were observed rarely.

규범 권력

김준석 한국국제정치학회 2006 한국국제정치학회소식 Vol.119 No.-

農藥(Pesticide)과 殺鼠劑(Rodenticide)의 中毒時 症狀 및 治療法

金俊錫,趙松子 한국병원약사회 1985 병원약사회지 Vol.2 No.2

조선시기의 주자학과 양반정치

金駿錫 역사실학회 2000 역사와실학 Vol.17·18 No.-

血栓性疾患과 高 Cholesterol 血症에 있어서의 血小板凝塊力 및 Aspirin과 Dipyridamole의 效果에 關한 硏究

金俊錫,徐舜圭 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.3

Although platelet have been implicated in the pathogenesis of the thrombotic disease, the platelet aggregability was not well studied in Korea. Author measured platelet aggregability in 103 clinical cases including 30 healthy volunteers to evaluate the platelet function and the effect of Aspirin and Dipyridamole on aggregability In Korean. 24 patients with cerebral thrombosis, 24 Patients with ischemic heart disease and 25 patients with hypercholesterolemia were included for this study. Aggregation tests were performed at three final concentrations of epinephrine (10uM/L) and ADP (4 uM/L, 10 uM/L) with platelet aggregometer which was made by Chrono-Log Corp. in all cases. Platelet aggregations were measured in patients who were treated with Aspirin, Dipyridamole and combined treatment of Aspirin and Dipyridamole respectively. The following results were obtained. 1 The mean maximal platelet aggregability in the normal subjects induced by 10 uM/L epinephrine was 59.3±24.25%, 66.6±14.00% in Bm and 62.5±19.30% in B5 in induction by 4 uM/L ADP, and 77.2±8.99% in Bm ad 76.6±9.83% in B5 in induction by 10 uM/L ADP. 2. The mean maximal platelet aggregability in patients with cerebral thrombosis induced by 10 uM/L epinephrine was 89.2±7.33%, 78.8±9.41% in Bm and 78.5±9.93% in B5 in induction by 4uM/L ADP, and 86.4±7.69% in Bm and B5 in induction by 10 uM/L ADP. The results showed significantly elevated platelet aggregability than that of normal subjects.(p<0.01) 3. The mean maximal platelet aggregability in patients with ischemic heart disease induced by 10 uM/L epinephrine was 88.1±11.99%, 78.2±12.50% in Bm and 76.3±15.66% in B5 in induction by 4 uM/L ADP, and 86.4±8.63% in Bm and B5 in induced by 10 uM/L ADP. The results showed significantly elevated aggregability than that of normal subjects.(p<0.01) 4. The mean maximal platelet aggregability in patients with hypercholesterolemia induced by 10 uM/L epinephrine was 86.8±15.99%, 82.7±11.19% in Bm and 82.0±12.87% in B5 in induction by 4 uM/LADP, and 88.5±11.47% in Bm and B5 in induction by 10 uM/L ADP. The results showed significantly elevated platelet aggregability than that of normal subject. (p<0.01) 5. The mean maximal platelet aggregability in patients with thrombotic disease was studied by Dipyridamole administration. The platelet aggregability induced by epinephrine before administration was 90.9±8.52% and after administration it was 78.9±15.68%, and the results showed that Dipyridamole lowered aggregability significantly. The platelet aggregability induced by 4 uM/L ADP before administration was 84.0±11.90% in Bm and B5 and after administration it was 78.0±11.44% in Bm and B5, and the results showed that Dipyridamole lowered aggregability but not significant. The platelet aggregability induced by 10 uM/L ADP before administration was 89.2±10.39% in Bm and B5 and after administration it was 80.5±8.44% in Bm and B5, and the results showed that Dipyridamole lowered aggregability significantly. 6. The mean maximal platelet aggregability in patients with thrombotic disease was studied by Aspirin administration. The platelet aggregability induced by epinephrine before administration was 91.0±4.79% and after administration it was 47.6±17.72%. The Platelet aggregability induced by 4 uM/L ADP before administration was 84.6± 10.37% in Bm and B5 and after administration it was 72.6± 11.85% in Bm and 65.3±15.97% in B5. The Platelet aggregability induced by 10 uM/L ADP before administration was 84.9±6.30% in Bm and B5 and after administration it was 77.7±8.60% in Bm and 75.0±8.89%. The results showed that Aspirin lowered aggregability markedly. 7. The mean maximal platelet aggregability in patients with thrombotic disease was studied by combined administration of Aspirin and Dipyridamole. The platelet aggregability induced by epinephrine before administration was 86.7±13.77% and after administration it was 36.7± 14.01%. The Platelet aggregability induced by 4 uM/L ADP before administration was 81.5±12.93% in Bm and 80.6±14.15% in B5 and after administration it was 54.7±17.27% in Bm and 44.6±21.17% in B5. The Platelet aggregability induced by 10 uM/L ADP before administration was 87.3±10. ll% in Bm and B5 and after administration it was 65.7±13.59% in Bm and 62.0±16.42% in B5. The results showed that combined administration of Aspirin and Dipyridamole lowered aggregability significantly and the results were lower than that of normal subjects. 8. The effects of combined treatment of Aspirin and Dipyridamole showed marked reduction of platelet aggregability than that of single treatment of Aspirin or Dipyridamole in thrombotic disease.

규범권력과 유럽연합: 새로운 국제정치 행위자의 등장?

김준석 서울대학교 국제학연구소 2007 국제지역연구 Vol.16 No.2

The following paper proposes to pay attention to the concept of normative power as a conceptual tool to understand the ways in which the European Union has emerged as a significant actor in world politics since the 1990s. While considerable progress has been made with regard to foreign and security policy coordination among the member states, it still remains very difficult to predict the overall shape of the EU as international actor. The concept of normative power can help highlight the fact that the EU, apart from engaging in conventional power politics, has been showing interest in propagating norms and values like democracy and human rights to other countries and regions. The following paper also points to the need for a theoretical framework with the help of which the concept can be made more persuasive, suggesting that the theory of communicative action by Jürgen Habermas might play such a role. 다음의 논문에서는 1990년대 이후 현저하게 강화되고 있는 국제정치행위자로서 유럽연합의 역할과 위상을 이해하기 위한 유력한 접근법으로서 규범권력(normative power) 개념에 주목할 것을 제안한다. 외교-안보 분야에서 협력의 진전에도 불구하고 유럽연합이 국제정치의 場에서 장차 어떤 모습을 취할지에 대해서는 정확한 예측이 어려운 상황이다. 최근 들어 유럽연합 연구자들 사이에서 활발하게 논의되고 있는 규범권력 개념에 따르면 유럽연합은 군사력과 경제력을 수단으로 하는 통상적인 권력 추구와는 별개의 차원에서 민주주의, 인권 등의 규범을 확산하고 전파하는데 관심을 지니는 존재로 이해될 수 있다. 다음의 논문에서는 유럽연합의 국제정치적 정체성의 기반으로서 규범권력 개념을 비판적으로 검토한다. 이와 함께 규범권력 개념에 보다 일반적 차원에서 타당성을 부여할 수 있는 이론적 기초가 결여되어 있음을 지적하고, 이와 관련하여 위르겐 하버마스의 의사소통행위이론이 유력한 분석틀로 기능할 수 있음을 제안한다.

유럽 정체성의 규범적 기초: 하버마스의 헌정적 애국주의를 중심으로

김준석 서울대학교 국제학연구소 2009 국제지역연구 Vol.18 No.4

This study aims at systematically highlighting the concept of constitutional patriotism proposed by Jürgen Habermas. The European Union is in need of drawing voluntary cooperation not only of member states but also of European citizens. This is especially the case as the integration is no longer solely about the promotion of economic cooperation but now includes politically sensitive issues which has been considered essential to the maintenance of sovereignty of member states. It is against such a backdrop that many scholars and commentators are proposing ways of forging a sense of common belonging among citizens with diverse political, national and cultural backgrounds. In contrast to more traditional type of identity which, based on common history, culture or language, emphasizes emotional attachment to one's own community, constitutional patriotism avoids becoming exclusive and aggressive by putting greater stress on universal and rational principles and institutions like human rights, freedom, democracy as the object of identification. Such an attempt to build a new identity, however, has its own difficulties, for constitutional patriotism as rational and universal identity raises a dilemma that defies an easy resolution. In particular, two questions arise here. First, is constitutional patriotism realistic enough? Second, is constitutional patriotism normatively valid? If so, on what grounds? How can we explain and justify the normative basis of constitutional patriotism? On the first question, Habermas offers a persuasive answer, drawing upon his general social theory. He claims it is fairly possible to bring constitutional patriotism into existence thanks to the overall increase in citizens' reflexive and critical ability in modern society. On the second question, on the other hand, his answer remains inconclusive, giving rise to confusion over the interpretation of the concept. To be more exact, the dilemma can be formulated as follows. Constitutional patriotism takes universal impartiality as its normative ideal. It is, however, also an attitude of loyalty and commitment to one's own community and its members. How, then, can we reconcile these conflicting claims of constitutional patriotism? To provide an proper answer to such a question, we need to go beyond Habermas's own account and to discuss and assess the normative validity of constitutional patriotism in the context of cosmopolitanism-communitarianism debate. That way, we can understand how it is possible for a citizen to remain loyal to his or her own community without having to give up cosmopolitan impartiality. We can also expect to have an opportunity to think not only about the question of European identity but also about the problem of “ethics of identity” in general. 본 논문은유럽정체성에관한최근의다양한논의들중특히위르겐하버마스등이제안한헌정적 애국주의(constitutional patriotism) 개념을 체계적으로 조명한다. 오늘날 유럽연합은 회원국 정부들뿐만 아니라 각 회원국 시민들, 즉 유럽시민들의자발적인 협력을 이끌어내야 할 필요성에 직 면하고있으며, 이에따라서로다른정치적, 민족적, 문화적배경을가진시민들에게일정한소속감 을 불러일으킬 방안이 다양하게 제시되고 있다. 이러한논의들 중 헌정적 애국주의는 공통의 역사와 문화, 언어 등을 중심으로 정서적인 친밀감을 형성하는것을 목표로 하는 전통적인정체성과는 달리 인권, 자유, 민주주의 등 보편적이고 합리적인 원칙과 제도를 정체성의 대상으로 삼음으로써 민족정 체성, 국가정체성의 배타적인 속성을 극복하려 한다. 하버마스는 현대사회에서 반성적, 비판적 능력 의 향상으로 인해이러한 새로운 정체성의 실현이 충분히 가능하다고 주장한다. 본논문에서는 특히 보다 일반적이고 추상적인 차원에서 헌정적 애국주의의 규범적 정당성을 이해할 것을 제안한다. 이 를 위해 본 논문에서는 세계시민주의와 공동체주의 간 논쟁의 틀 속에서 헌정적 애국주의를 평가할 것을제안한다. 이러한시도를 통해 세계시민주의의 불편부당성을 옹호하는 헌정적 애국주의가 특정 국가나공동체에대한충성과헌신을어떻게정당화할수있는지보다잘이해할수있다. 또한유럽 정체성의 문제를 보다 잘 이해할 뿐만 아니라 “정체성의 윤리학” 일반에 대해 체계적으로 생각해볼 수있는기회를얻을수있을것이다. 이를위해본논문에서는유럽정체성에관한기존논의를간략 하게 개관한 후 헌정적 애국주의라는 새로운 정체성의 현실적 가능성에 관한 하버마스의 주장에 주 목한다. 또한 헌정적 애국주의의 규범적 기초를 국제규범이론의 틀에서 살펴는 가운데 특히 규범적 정당성의 측면에서헌정적 애국주의의세계시민주의적인 측면과애국주의적인측면의화해가어떻게 가능한지의 질문에 대한 답변을 모색한다.

청소년의 학교스포츠클럽 참여시 재미요인과 운동정서 및 인성발달과의 관계

김준석 한국스포츠학회 2022 한국스포츠학회지 Vol.20 No.2

The purpose of this study is to investigate the relationship between enjoyment factors, exercise emotions, and personality development when adolescents participate in school sports clubs. To this end, 100 copies were distributed to 3 schools located in A Metropolitan City and 3 schools located in B and C, which are conducting school sports clubs and a total of 583 copies were analyzed, excluding 17 unfaithful copies. For data processing, frequency analysis, validity and reliability verification, exploratory factor analysis, and correlation analysis were performed using SPSS 24.0. In addition, in order to verify the research hypothesis, the following conclusions were drawn by conducting confirmatory factor analysis and structural equation model analysis using the AMOS 22 program. First, it was found that Enjoyment factors when adolescents participate in school sports clubs have a positive effect on exercise emotions. Second, it was found that Enjoyment factors when adolescents participate in school sports clubs have a positive effect on personality development. Third, it was found that exercise emotions had a positive effect on personality development when adolescents participated in school sports clubs. 본 연구의 목적은 청소년들의 학교스포츠클럽 참여시 재미요인과 운동정서 및 인성발달의 관계를 알아보고자 한다. 이를 위하여 학교스포츠클럽을 실시하고 있는 A광역시에 소재한 3곳과 B시, C시에 위치한 3곳 총 6개 중학교에 각각 100부씩 배부 하였으며, 불성실한 17부를 제외한 총 583부를 분석하였다. 자료처리는 SPSS 24.0을 이용하여 빈도분석, 신뢰도 분석과 탐색적 요인분석, 상관분석을 실시하였으며, 연구가설을 검증하기 위하여 AMOS 22를 이용하여 확인적 요인분석 및 구조방정식 모형분석을 실시하여 다음과 같은 결과를 얻었다. 첫째, 청소년의 학교스포츠클럽 참여시 재미요인은 운동정서에 정적인 영향을 주는 것으로 나타났다. 둘째, 청소년의 학교스포츠클럽 참여시 재미요인은 인성발달에 정적인 영향을 주는 것으로 나타났다. 셋째, 청소년의 학교스포츠클럽 참여 시 운동정서는 인성발달에 정적인 영향을 주는 것으로 나타났다.