고양이 위 평활근에서 KCI에 의한 근수축에 대한 Protein Kinase의 조절

심상수,김승록,심혜선,이덕주,한상준,윤신희,조양혁,김명석 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.3

신생아 외과질환의 임상적 고찰

김인구,박상록 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.2

Neonatal surgery is a more specialized field in pediatric surgery and to a large extent the surgery of congenital malformations. Authors reviewed the neonatal surgical diseases and tried to find problems in the management of these patients at the department of general surgery, Chungnam National University Hospital from Aug. 1983 to Oct. 1984. 12 nonatal surgical disease were collected among 129 pediatric surgical patients which were 3 jejunal atresias, 2 gastroschisis, 2 ompholocele, 1 Hirschsprung's disease, 1 anorectal anomaly and 3 congenital hypertrophic pyloric stenosis. Mortality developed in 3 patients all of whom needed a long term parenteral hyperalimentatiion Two of 3 fatal cases were premature neonates.

竝流흐름 氣泡塔內에서 가스 홀드업에 관한 硏究 : Specially on aqueous of inorganic salts 無機鹽 水溶液을 中心으로

李相錄,金相烈 東亞大學校 大學院 1983 大學院論文集 Vol.7 No.-

Gas hold-up was studies according to the changes of Gas and liquid velocity, physical properties, geometrical type of distributor, and temperature for aqueous solution of inorganic salts in a cocurrent flow bubble column. The results were as follows: 1. σf decreases according to the concentration increases. especially this phenomenon was remarkably appeared in aqueous solution of potassium nitrate. 2. The effect of temperature on the gas hold-up was not found when the gas velocity is less than 3.65 cm/sec, but gas hold-up with temperature increase of solution rises up beyond gas velocity of 3.65 cm/sec. 3. The effect of solution velocity to the gas hold-up was not found when the solution velocity is less than 1.76 cm/sec, but gas hold-up with solution velocity increase lay down beyond solution velocity of 1.76 cm/sec. 4. The nondimensional equation by experimental data was represented in equation(7),(8).

응급의학과 의사가 시행한 상복부 초음파의 정확성

하영록,김훈,유승,정성필,김승환,유인술 대한응급의학회 2002 대한응급의학회지 Vol.13 No.4

Purpose: The purpose of this study is to determine for upper abdominal pain, the accuracy of emergency abdominal ultrasonography (EAU) performed by emergency physicians with limited training. Methods: Two PGY-3 emergency physicians, who had received 2 hours of hands-on training, including the normal anatomy of a biliary system, liver, kindney, spleen, and pancreas, and who had studied the pathologic findings for another month were the subjects of this study. They used a Sonosite 180? to perform EAU on patients with upper abdominal pain within 2 months after training. We determined the agreement between the radiologist’s abdominal ultrasonography(RAU) and EAU by using Kappa statistics. Results: A total of 59 patients were enrolled. The agreement between the EAU and the RAU findings was 0.97, 0.88, 0.79, 0.73, 0.62, and 0.57 for gall bladder (GB) distension, cholelithiasis, GB wall thickening, duct dilatation, choledocholithiasis, and pericholecystic fluid, respectively (p<0.05). Conclusion: The results of EAU, performed by emergency physician with limited training on patients suffering from upper abdominal pain had a significant agreement with the RAU. However, more educations and cautions are warranted for diagnosing pericholecystic fluid and choledocholithiasis.

응급실에서의 확산강조 자기공명 영상

정성필,이석우,양영모,하영록,김승환,유인술 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: This study was designed to review the cases of patients who had undergone diffusion-weighted magnetic resonance imaging(DWI) in the emergency department(ED), and to investigate its clinical usefulness and current indications. Methods: We analyzed the cases of 152 consecutive patients who underwent DWI in the ED from Jan to Mar 2001. DWI was obtained with the use of a multislice, single-shot, spin-echo plana imaging technique(GE SignaR). Imaging time was less than one minute. The medical records, the DWI films and the computed topography results were reviewed. We investigated the chief complaint, initial findings of physical examination, final diagnosis, decision-making department, interval from admission to imaging, and DWI findings. Results: DWI showed positive findings of high signal intensity in 84 patients(55.3%). Among the 68 patients who yielded a negative result, false negative occurred with 12 patients(17.6%): 10 lacunar infarctions, a pons infarction, and a brainstem infarction. Eleven patients were determined as having a cerebral hemorrhage, all of whom showed the abnormal finding of a mixed signal in DWI. The sensitivity and the specificity of DWI to rule out stroke were 85.5% and 98%, respectively. Current indications for DWI in our ED are age older than 60, alert mental status, and one of the symptoms or signs among lateralyzing sign, language disturbance, and dizziness/vertigo. Conclusion: DWI was highly specific to rule out stroke, so emergency care professionals should be familiar with this new technology. Further prospective study is required to determine the proper indications and clinical usefulness of DWI in the ED.

노인 외상 환자의 중증도 분류 시 Triage-revised Trauma Score의 의의

양영모,하영록,정성필,김승환,유인술 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Backgrouds: The mortality of geriatric trauma patients is higher than that of other age groups. However, little research has been done the methods or criteria of triage for geriatric trauma patients. This study evaluated a clinical significance of the triage-revised trauma score(t-RTS) for triage of geriatric trauma patients. Methods: We retrospectively analyzed clinical data on 528 trauma patients over 65 years of age who were treated from Jan 1999 to Dec 2000. The t-RTS was calculated utilizing the RR(respiratory rate), SBP(systolic BP), and GCS scores and the ISS was abstracted from the final diagnosis. The obtained t-RTS and ISS were evaluated using the measures of sensitivity, specificity, accuracy, and AUC curve. Results: The overall mortality rate was 9%, and there was no significant differences between the survival group and the mortality group according to age and sex. The mean scores of SBP, RR and GCS of the survival group were significantly higher than those of mortality group(p=0.001). The mean of t-RTS and RTS of the survival group were also significantly higher(p=0.001), but the ISS was significantly higher in the mortality group(p=0.001). The t-RTS, RTS, and ISS showed good prediction rates on the ROC curve(p=0.001), and the AUC value was higher in the ISS than in the t-RTS and the RTS. The sensitivity and the accuracy were high in the t-RTS and the RTS, and the specificity was high in the ISS. The t-RTS is less than 10 for a survival probability of 50% or less Conclusions: Implementation of the t-RTS in the triage of geriatric trauma patients in the field and in emergency room would be very useful. The probability of death in geriatric trauma patients is high when the t-RTS is less than 10.

朝鮮朝 書院敎育의 實際와 社會的 役割에 關한 硏究

張德三,李鐘祿,辛堯永,金俊基,李相基 圓光大學校 敎育問題硏究所 1989 敎育硏究 Vol.- No.8

The brief contents about the background of the appearance of Seo-won in Yi-Dynasty, the actual state of its education and its social role are as follows : 1. Our nation’s Seo-won was not settled as a Confucian educational institute until Sun Confucianism (性理學) was introduced in the middle of Yi-Dynasty. 2. The ultimate purpose of the Seo-won education was to establish the permanent aim of the following saints (法聖賢) and to cultivate sages by laying emphases on the ethical and moral education and the state examination education. 3. So-hak (小學) and Ka-lye (家禮) were introductory courses and Sa-se (四書) and Oh-kyeong (五經) were fundamental ones in the contents of education. 4. It took the educational method of Joo Ja (朱子) in Song-Dynasty and emphasized practical moral education by autere training syatem. 5. They administered it by the income of real estate which they secured, while they expanded its paddy fields with surplus income. 6. The educational system and equipment of Seo-won was similar to that of China which had a director and Yoo Sa (有司) system although there was some difference according to the class of Seo-won. 7. Seo-won did its duty as the distribution of information, the promotion of Confucianism, the enlightment of their countries, the inheritance of their traditional culture, the foundation of science and the publication or custody of publications.

전자선치료시 유효 선원 피부간 거리 결정에 관한 연구

이병구,이상록,정덕양,권영호,김유현 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.2

Under the various clinical circumstances, there is a condition to change source to skin distance(SSD). It is possible to correct photon beam by well-known inverse square law. On the other hand, the electron beam is not exact location of source, that's why it is difficult to apply as it is. In case of electron beam, we should correct the difference of SSD by measure effective SSD . There are many ways to measure effective SSD. In this study, Faiz Khan's method was used. The measurement energy is 6,9,12,16,20 MeV and field size is set standard applicator 6×6, 10×10, 15×15, 20×20, 25x25㎠. From the bottom of the standard applicator to skin distance is set to 5㎝. So we measured dose at the gap to 0∼20㎝. According to a production company of linear accelerator, or even though same production company, the qualities of electron beam can be different. So, effective SSD can be different every several accelerator. Therefore, it is desirable to use the effective SSD measured at every electron beam energy and field size actually.

견인방법에 의한 PEG 제거 후에 발생한 대량 출혈 1예

김재권,김영관,이영록,박상모,조성구,구소영,이연수,최지용,김현승,김영호 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Redox regulation of the tumor suppressor PTEN by glutathione

Kim, Yujeong,Song, Yong Bhum,Kim, Tae-Youl,Kim, Inyoung,Han, Seong-Jeong,Ahn, Younghee,Cho, Seung-Hyun,Choi, Cheol Yong,Chay, Kee-Oh,Yang, Sung Yeul,Ahn, Bong Whan,Huh, Won-Ki,Lee, Seung-Rock Elsevier 2010 FEBS letters Vol.584 No.16

<P><B>Abstract</B></P><P>Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) expressed in <I>Saccharomyces cerevisiae</I> was reversibly oxidized by hydrogen peroxide and reduced by cellular reductants. Reduction of hPTEN was delayed in each of <I>S. cerevisiae</I> gsh1Δ and gsh2Δ mutants. Expression of γ-glutamylcysteine synthetase Gsh1 in the gsh1Δ mutant rescued regeneration rate of hPTEN. Oxidized hPTEN was reduced by glutathione in a concentration- and time-dependent manner. Glutathionylated PTEN was detected. Incubation of 293T cells with BSO and knockdown expression of GCLc in HeLa cells by siRNA resulted in the delay of reduction of oxidized PTEN. Also, in HeLa cells transfected with GCLc siRNA, stimulation with epidermal growth factor resulted in the increase of oxidized PTEN and phosphorylation of Akt. These results suggest that the reduction of oxidized hPTEN is mediated by glutathione.</P>