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Short Communication: HIV-1 Transmission Networks Across South Korea
Ahn, Mi Young,Wertheim, Joel O.,Kim, Woo Joo,Kim, Shin-Woo,Lee, Jin Soo,Ann, Hea Won,Jeon, Yongduk,Ahn, Jin Young,Song, Je Eun,Oh, Dong Hyun,Kim, Yong Chan,Kim, Eun Jin,Jung, In Young,Kim, Moo Hyun,Je Mary Ann Liebert 2017 AIDS RESEARCH AND HUMAN RETROVIRUSES Vol.33 No.8
Ann Ji-Young,Sa Soo-Jin,Cao Yang,Lee Sang-Young,Cheon Hee-Tae,Yang Boo-Keun,Park Choon-Keun The Korean Society of Animal Reproduction 2006 Reproductive & developmental biology Vol.30 No.2
The present study was conducted to investigate the effects of cumulus cells and porcine follicular fluid (pFF) on plasminogen activator (PA) activity and oocytes maturation in vitro in the pig. The cumulus-oocyte complexes (COCs) and denuded oocytes (DOs) were incubated in NCSU-23 medium with or without 10% pFF for 0, 24, or 48 hr. In the presence of cumulus cells, the proportions of oocytes matured to metaphase-II stage were significantly (P<0.05) higher in medium with pFF than without pFF (69.8 vs. 37.7%, respectively). When COCs and DOs were cultured in the presence of pFF, tissue-type PA (tPA), urokinase-type PA (uPA), and tPA-PA inhibitor (tPA-PAI) were observed in COCs, and PA activities were higher at 48 hr than 24 hr. When COCs and DOs were cultured in the absence of pFF, tPA and tPA-PAI were observed in COCs, and PA activities were increased as duration of culture increased. No PA activities were detected in DOs regardless of pFF supplementation. When porcine oocytes were cultured in the presence of pFF for 24 and 48 hrs, the activities of tPA-PAI, tPA, and uPA were observed in both COCs and DOs. In medium of absence of pFF, PA activities were observed in oocytes with cumulus cells only. On the other hand, three plasminogen-dependent lytic bands (tPA-PAI, tPA, and uPA) were observed in pFF cultures. Particularly uPA activity was higher than the other kinds of PA activity. When oocytes and cumulus cells were separated from porcine COCs at 0 hr of culture, tPA-PAI, tPA, and uPA were detected in cumulus cells at 48 hr of culture, but no PA activities were in DOs. The presence of pFF and cumulus cells in maturation medium stimulated not only nuclear and cytoplasmic maturation in porcine COCs, but also PA production by cumulus cells and COCs. It is possible that PAs produced by cumulus cells migrated through the gap junction between oocyte and cumulus cells. These results suggest that porcine oocytes have no ability to produce PA themselves.
A Public Perception Study on the new word "Corona Blue":Focusing on Social Media Big Data Analysis
Ann, Myung Suk The International Promotion Agency of Culture Tech 2020 International Journal of Advanced Culture Technolo Vol.8 No.3
The purpose of this study is to contribute to the provision of basic data for psychological quarantine policy and counseling by examining the public perception of the "corona blue" phenomenon through analysis of social media big data. To do this, key words related to the word 'Corona Blue' were derived and analyzed using the big data analysis program 'Textom'. As a result of the analysis, words such as 'Corona 19', 'depression', 'problem' and 'overcome' were derived as key words. For the analysis results,"pride and awarenes as the public perception of Corona 19", "depression and anxiety as a group trauma as the corona blue phenomenon", "spreading a psychological quarantine culture and demanding social healing as the perception of overcoming corona Blue," and "hope for return to daily life and changes in daily life as the perception of post corona" were discussed. In conclusion, we have identified the need for active psychological support from the community By revealing that Corona Blue is a depression as a group trauma. At this time, it is confirmed that it is necessary to prioritize social healing and psychological quarantine for the main risk groups such as youth or the vulnerable, who are the socially weak.
김운기,Jin-Soo Park,Ok-Ju Sul,Jae-Hee Seo,최범규,Hee-Young Park,Anne M. Latour,Beverly H. Koller,권병세,Choon-Soo Jeong 한국분자세포생물학회 2011 Molecules and cells Vol.31 No.2
Previous work has suggested that the LIGHT-TR2 costimulatory pathway plays a role in the acute and chronic stages of dextran sulfate sodium (DSS)-induced colitis [Steinberg et al. (2008); Wang et al. (2005)]. To clarify the role of TNFR-related 2 (TR2) signaling in the maintenance of intestinal homeostasis, we generated a TR2 knock-out (KO) mouse. Using DSS to induce colitis, we compared the colitic symptoms and pathological changes in wild type (WT) and TR2 KO mice, and the production of cytokines by the diseased colons. We also studied the role of TR2 in suppressing innate and adaptive immunity in the DSS model. TR2 deficient mice were characterized by reduced symptoms of intestinal inflammation compared with wildtype mice, and reduced production of cytokines. We therefore generated a monoclonal antibody against mouse TR2 which was specific to TR2 and capable of blocking TR2 signals. With this antibody, we demonstrated that antagonizing TR2 during the development of DSS-induced colitis reduced the symptoms of inflammation. Our findings suggest that TR2 is an important mediator in colitis, and may serve as a therapeutic target in inflammatory bowel disease.
박 진,이경운,김춘호,김성중,조남수,안태훈 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3
A case of quadriplegia resulted from cervical penetrating wound was admitted to chosun university hospital intensive care unit, and undergone steroid therapy and antibiotics therapy. On the 6th hospital day, the septic complication was developed and it proved to be bacterial meningitis by CSF examination. Broad spectrum antibiotics was administered immediately after and the diagnosis and the patient was monitored carefully. The bacterial meningitis was improved and no other serious complication was developed. The patient was discharged with permanent neurologic deficit, quadriplegia.