Selenium 공급방법이 수경재배 토마토의 생장과 Se 흡수에 미치는 영향

이철규(Cheol-Kyu Lee),조경철(Kyung-Cheol Cho),이정현(Jeong-Hyun Lee),조자용(Ja-Yong Cho),서범석(Beom-Seok Seo),양원모(Won-Mo Yang) (사)한국생물환경조절학회 2005 생물환경조절학회지 Vol.14 No.4

토마토 ‘모모타로’를 공시하여 셀레늄 10㎎ㆍL?¹의 관주 및 엽면시비 등의 단용 및 혼용처리가 수경재배 토마토의 생육 및 과실 내 셀레늄 축적 함량에 미치는 영향을 구명하였다. 토마토 종자를 50공 트레이에 파종하여 70일 동안 육묘한 후 유묘를 코코피트 슬라이브를 이용한 수경재배 시스템에 정식하였다. 양액은 일본원예시험장 배양액 표준처방으로 조성하였으며, pH 5.8~6.2와 EC 2.3 ㎎ㆍL?¹ 등으로 조절하여 공급하였다. 셀레늄은 무기태 SeO₂와 sugar fatty acid ester에 킬레이트화 한 유기태 셀레늄을 10 ㎎ㆍL?¹으로 조성하여 관주, 엽면시비, 관주와 엽면시비를 병행하여 처리하였다. 초장, 엽수, 엽면적 및 엽록소 등의 토마토 생장반응은 셀레늄의 엽면시비, 그리고 엽면시비와 관주를 병행한 처리구에서 현저히 증가하였다. 과실 내 셀레늄 축적 함량은 킬레이트화 한 유기태 셀레늄을 엽면시비와 관주를 병행하여 처리한 경우에 0.302 ㎎ㆍL?¹으로 가장 높았다. 무기태와 유기태 셀레늄의 엽면시비와 관주 등의 단용 처리 보다는 혼용 처리가 전반적인 과실 생장과 체내 셀레늄 축적에 효과적이었다. 무기태 설레늄(SeO₂) 보다는 sugar fatty acid ester에 킬레이트화한 유기태 셀레늄 처리가 셀레늄을 함유한 기능성 토마토의 수경재배에 더 효과적이었다. This study was conducted to clarify the effects of supplying methods of selenium on the growth and Se uptake of hydroponically grown tomato plants. Tomato seeds (Lycopersicum esculentum Mill. cv. Momotaro T-93, Daki Seed Co.) were sown in plug tray with fifty holes, and raised for sixty days. Tomato seedlings transplanted to coco fiber slabs were supplied with the nutrient solutions adjusted to EC 2.3 dSㆍm?¹ and pH 5.8~6.2 recommended by the Japanese Horticultural Experiment Station. Selenium forms used were inorganic SeO₂ (here in after referred to Se) and organic selenium chelated with sugar fatty acid ester (here in after referred to chelated-Se). 10 ppm selenium solutions were treated to tomato plants with foliar applications, drenching, and foliar application plus drenching. Growth characteristics in terms of plant height, number of leaves, leaf area and chlorophyll content were significantly increased in the plot of foliar application of Se, and in the plot of foliar application plus drenching of chelated-Se than other plots, respectively. Transported contents of selenium into the tomato fruits were highest as 0.302 ppm in the plot of foliar application plus drenching of chelated-Se. Also, it had tended to be higher in the plot of foliar application plus drenching than in the plots of foliar application or drenching in both of Se and chelated-Se. Foliar application and drenching of organic chelated-Se were effective to produce the functional tomato fruits.

EEA 자동 봉합기를 이용한 저위전방절제술에서 콘돔(Condors)을 이용한 문합부 보호술의 효과

윤서구,황덕원,최경우,우제홍 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.4

라돈 자핵종의 알파 측정용 여과지 매질의 평가

서경원,Knutson, Earl O 대한방사선 방어학회 1992 방사선방어학회지 Vol.17 No.1

라돈 자핵종의 알파 측정용 여과지 매질에 대한 평가를 위한 연구는 물리적 특성조사로 여과지의 정전하 충전과 역학적 강도가 조사된후, 시료채취 전과 후 여과지에 부가되는 압력차로 여과지의 성질을 시험하였으며, 알파 스펙트럼분석으로 여과지내 부착된 라돈 자핵종의 에너지스펙트럼을 분석하여 성능지수를 계산한 후 여과지의 특성을 비교 평가하였다. 평가의 결과 새로운 여과지 매질은 과거의 표준인 Millipore AA보다 크게 유리한 점은 없었으나, 정전하가 문제되는 곳에서는 Metricel DM-800을 권고하였다. 또한 평가방법은 새로 개발될 여과지들의 물리적 특성과 매질의 수집효율을 고려하여 라돈 자핵종의 알파 측정용 여과지 매질 평가를 위해 유용하게 사용될 수 있을 것이다. A study for the evaluation of selected filter media that need further characterization particularly in the context of alpha measurements of radon progeny has been carried out by investigating physical characteristics and using the alpha sepectros-copy. Physical characteristics was investigated by electrostatic charging and mechanical strength of filters, and then pressure drop before and after sampling was tested. Alpha spectroscopy was used to analyze the energy spectra from the deposition of radon progeny into filters. The results of the assessment showed that the newer filter types do not have a great advantage over the "old standard", Millipore type AA. But Metricel DM-800 is recommended for those situations where electrostatic charging is a problem. Also this method will be sued more effective for the evaluation of new developing filters in future.

위암환자에서 수술 전 내시경생검 조직검사와 수술 후 조직검사의 변동

서경원,이상호 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Background : This study was carried out in order to investigate the discrepancy between the histology obtained through the preoperative endoscopic biopsy and post operative resection. Methods :To analyse the factors affecting the discrepancy 280 cases, in 270 gastric adenocarcinoma patients who underwent surgical operation in this hospital since 1st August, 2004, to 31st July 2005, were subjected to present study. Histologic types were categorized into well-differentiated tubular(WD-T), moderately-differentiated tubular(MD-T), poor-differentiated tubular(PD-T), signet ring cell carcinoma, and papillary adenocarcinoma(Pap). The data is gender, tumor marker, concordance of pathologist, tumor location, T and N factor, and stage in this study Results : From the cases exhibiting WD-T, MD-T, PD-T, and SRC in endoscopic biopsy,52.9%, 60.4%,38.9% and 65.6%, respectively, showed the same pathology in resected specimen. The sensitivity was analysed as 70.3%, 52.9%, 26.9%, 80% respectively. For the statistically significant factors affecting the pathologic discrepancy, male patient showed higher discrepancy. In this cases, the discrepancy rate of gender is 49% in male, 34% in female patients with elevated CEA level had higher discrepancy. And that is statistically significant factors affecting the pathologic discrepancy. However, Patients with elevated CA19-9 levels also showed higher discrepancy, but no significance. Also, There is no difference about discrepancy according to concordance of pathologists who reported histologic biopsy, in the preoperation and postoperation. When discrepancy was presented, 44.9% was reported in accord case, 44.2% was reported in discord case with respect to pathologist. As for the discrepancy following the location of tu or, data showed less discrepancy, in cases where tumor was located at the lower 1/3, but this showed no significance. In the change of pathologic results based on T,N factor, It showed no significance.but, it is noticeable in mucosal, submucosal cancer that was reported 32.2% and 57.4% present rate of discrepancy, patients with elevated stage had higher discrepancy, but this showed no significance. Conclusions : The statistically significantly factors that affected the pathologic discrepancy were gender, and rise in CEA level. Mucosal and submucosal cancer showed discrepancy in 32.5% and 57.4% respectively, and further study is thought to be necessary. Also, further retrospective study with more cases is thought be needed for early gastric adenocarcinoma

응급실 내원 환자의 만족도 평가 및 관련 요인에 대한 연구

서강석,감신,박정배,이정헌,김종근,윤영국,곽경숙,이원기,우석정 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: To examine the influencing factors on patients' satisfaction in the emergency department(ED) for quality assurance. Methods: Patients who visited to the ED were prospectively investigated from November 1 to December 31, 1997. Authors developed questionnaire to investigate influencing factors on patients' satisfaction. A Chi-square test and LISREL 7.0 were applied for statistical analysis. Results: Patients' satisfaction was significantly related to physical environment variables, accessibility variables, kindness of hospital personnel variables, and patient's trust for doctors variables. In path analysis, willingness for revisit was influenced by patients' satisfation, accessibility, physical environment, patients' trust for doctors in order, and willingness for recommendation was influenced by accessibility, patients' satisfaction, and kindness of hospital personnel in order. Conclusions: The influencing factors on patients' satisfaction are physical environment, accessibility, kindness of hospital personnel, and patient's trust for doctors. Willingness for revisit and willingness for recommendation are influenced by patients' satisfation. In spite of some limitations, the results of this study can be used as a baseline information for exploring the influencing factors on patients' satisfaction. Further comprehensive research efforts should be made on the study of patients' satisfactoin in the ED.

퇴행성 슬관절염 환자의 증상 중증도 지표와 DITI의 상관성 연구

서병관,류성룡,강중원,안경애,이재동,최도영,김건식,이두익,이윤호,이상훈 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : To investigate the applicability of thermography as severity measurement in the patients with osteoarthritis (OA) of the knee. Methods : Data were obtained from 80 patiens with OA of the knee. They were asked to answer two disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index, Lequesne's Functional Index (LFI)), one generic instrument (Korean Health Assessment Questionnaire (KHAQ)), VAS in order to assess the severity of disease, quality of life, degree of pain and taken thermography in standardized environment. Results : The thermal difference between ipsilateral side and contralaterla side of lateral aspect of knee was correlated with that of medial aspect of knee, and the thermal difference of anterior thigh was correlated with that of lateral, medial aspect of knee and patella region. Age, duration of disease, duration of morning stiffness, sex, crepitus, and painful side of knee were not correlated with the thermal differences of each region. LFI, WOMAC, WOMAC pain subscale, WOMAC stiffness subscale, WOMAC physical function, KHAQ,, VAS were not correlated with the thermal differences of each region. Conclusion : Further study on the thermography on OA of the knee in population with appropriate severity grade and the standardization of analysis of thermographic data were recommended.

혈중 아연농도와 위암환자의 임상 병리학적 상관성

서경원,윤기영 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

Objective: Until it was recently overtaken by stomach cancer was the most common cancer in the world. It is still a major cause of death in many countries. Previous most presentation is a discussion of the possible role of micronutrients in the etiology of common human cancers. The aim of this study is to explore the relationship between the Zinc trace elements and clinicopathologic nature in gastric carcinoma. Methods: Trace element Zn were measured in primary gastric carcinoma from 189 patients. It was compared with age, cancer stage, cancer location and pathological types with the contents of Zn. Results: There were no significant differences in the contents of Zn among primary gastric tumors, age (P=0.207 post hoc test), and no significant differences in the contents of Zn between gastric cancer stage (P=0.688 post hoc test). There were no significant differences in the contents of Zn among primary gastric tumors, location (P=0.99 post hoc test), and no significant differences in the contents of Zn between gastric cancer WHO pathological type (P=0.553 post hoc test). Conclusions: There were no significant differences in the contents of Zn among primary gastric tumors, age, cancer stage, cancer location and WHO pathological type.

라돈을 제어하는 환경에서 라돈 자핵종의 농도 결정

서경원,이병기 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.1

본 연구에서는 환기장치로 제어하는 환경인 라돈 표준실 및 라돈 발생기로부터 이론적으로는 Jacobi 모델 이론을 사용하여 라돈 자핵종의 농도를 계산하였으며, 실험적으로는 두 발생 조건으로부터 채취된 시료를 알파스펙트럼 분석법에 의해 측정 분석하여 그 농도를 결정하였다. 이론적인 계산치와 실험적인 측정결과를 비교해 본 결과 매우 잘 일치되는 좋은 결과를 얻게 되었다. 따라서 이러한 연구는 실내 라돈환경에서 라돈 자핵종의 알파방출체에 의한 내부피폭선량을 보다 정확히 평가하고, 라돈 자핵종의 개별 농도를 신속히 결정하는 데 크게 기여할 것이라 사료된다. A standard radon chamber and a radon generator adjusted by ventilation system which had used in this research were assumed to calculate theoretically the concentration of radon progeny using Jacobi model theory. On the one hand, the filter sampled from the radon standard chamber and the radon generator was measured and analysed by the alpha spectrometry method. It is clear that measured result shows a good agreement contribution to more accurate internal dose assessment by alpha emission of radon progeny in indoor radon environment, and fast individual measurement and determination of concentration for radon progeny.

한국형 우울장애 약물치료 알고리듬 2006 (Ⅰ)

서정석,민경준,김원,석정호,박원명,송해철,이상열,전덕인,전현태,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

Objectives : Since the publication of Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management for depressive disorder. We revised KMAP-MD to Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. This paper is one of the following 4 papers consisting of Korean pharmacological algorithm for depressive disorder. Methods : The questionnaire consisted of 4 parts ; initial treatment of 1) non-psychotic depressive disorder, 2) psychotic depressive disorder, 3) treatment strategy for clinical subtypes and drug choice considering adverse effects, and 4) treatment for depressive disorder in women. It was composed of 22 questions, and each question had 54 sub-items. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. We classified the expert opinion to 3 categories (the first-line, the second-line, or the third-line). Results : For non-psychotic major depression, regardless ofthe severity of an episode, the antidepressant (AD) monotherapy was the optimal first-line treatment. SSRI, venlafaxine, and mirtazapine were the 1st-line AD. In case of a partial or no response to initial strategy, adding another AD was recommended. For psychotic major depression, combination of an AD and an atypical antipsychotic (AAP) was the treatment of choice. Among AAPs, quetiapine, rispendone, olanzapine were preferred. For non-responder to initial strategy, the next step was adding or changing AD before changing AAP. For women with premenstrual dysphoric syndrome or postpartum depression without psychotic features, AD monotherapty was a preferred strategy while for psychotic postpartum depression, combination of AD and AAP was recommended. Experts recommended various ADs according to adverse effect. Conclusion : These results suggest that the medication strategies for depressive disorder are rapidly changing and reflect the recent studies and clinical experiences.

비만을 동반한 위암 환자에서 두 병을 같이 수술 치료한 경험(증례)

최경현,윤기영,문형환,신연명,서경원,안수미,송윤미,석정희,정경연,이은하 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.3

Obesity is growing problem in Korea. We had a case of bariatric surgery during gastric cancer operation. Patient was 29 year old Korean lady with early gastric cancer located in the lesser curvature side of the middle 1/3 of the stomach. Her body weight was 89 kg, height 163 cm, and thus body mass index was 33.5 kg/m2. Preoperative blood pressure was 130/90 mmHg, hemoglobin 12.9 g/dL, total lymphocyte count 3,280/mL, serum albumin 4.3 g/dL, CEA 1.1 ng/mL, CA 19-9 9.1 ng/mL, and alpha fetoprotein 2 ng/mL. Another associated disease was right thyroid follicular neoplasm. The chest X-ray was normal. After IM injection of 2,500 units of heparin 30 minutes before the induction of general anesthesia, she received curative subtotal gastrectomy and Roux en Y gastrojejunostomy when a malabsorption loop of 120 cm jejunum was incorporated between the Treitz ligament and the end to side jejuno-jejunostmy site at May 29th 2006. Her postoperative course was uneventful except a minor wound seroma and the elevations of serum amylase(up to 4 folds) and lipase(up to 2 folds). She lost her body weight 9 kg in 5th, 21 kg in 7th, and 27 kg in 10th postoperative months to became 61.5 kg. On follow up exams in July 2008, she gained 4 kg to overcome her weakness and fatigue. From the above result, the incorporation of a malabsorption loop during reconstruction phase of gastric cancer operation was a good option for obese gastric cancer patients especially in cases of early gastric cancer.