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40X40 픽셀 어레이 CMOS 실리콘 망막칩의 설계 및 제조
김종문,김호운,신장규,히로오 요네즈 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
In this research, we have designed and fabricated a 40X40 pixel array retina chip which performs edge extraction by using CMOS standard process. The functions of photoreceptors, horizontal cells and bipolar cells have been implemented with semiconductor devices and circuits. In previous retina chips, spatial smoothing of input image has been implemented by resistive networks, which occupy a large chip area with a reduced area for effective photosensing due to a large number of required metal wires for interconnection. In this research, we have fabricated a retina chip which simplifies the wiring between pixels by using distributed-MOSFETs.
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Lee, Nam-Hun,Seo, Chang-Seob,Lee, Ho-young,Jung, Da-Young,Lee, Jun-Kyung,Lee, Jin-Ah,Song, Kye Yong,Shin, Hyeun-kyoo,Lee, Mee-Young,Seo, Young Bae,Kim, Hokyoung,Ha, Hyekyung Hindawi Publishing Corporation 2012 Evidence-based Complementary and Alternative Medic Vol.2012 No.-
<P>The fruit of <I>Cornus officinalis </I>Sieb. et Zucc. is commonly prescribed in Asian countries as a tonic formula. In this study, the hepatoprotective effect of ethanolic extracts of the fruit of <I>C. officinalis</I> (ECO) was investigated in a mouse model of acetaminophen- (APAP-) induced liver injury. Pretreatment of mice with ECO (100, 250, and 500 mg/kg for 7 days) significantly prevented the APAP (200 mg/kg) induced hepatic damage as indicated by the serum marker enzymes (AST, ALT, and LDH). Parallel to these changes, ECO treatment also prevented APAP-induced oxidative stress in the mice liver by inhibiting lipid peroxidation (MDA) and restoring the levels of antioxidant enzymes (SOD, CAT, and HO-1) and glutathione. Liver injury and collagen accumulation were assessed using histological studies by hematoxylin and eosin staining. Our results indicate that ECO can prevent hepatic injuries associated with APAP-induced hepatotoxicity by preventing or alleviating oxidative stress.</P>
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한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고
양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1
The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.
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S-36 Optimal fasting period after gastric ESD
( Kyoo Ho Choi ),( Sang Jin Lee ),( Jae Hyuck Jun ),( Sa Young Shin ),( Yoon Kyoo Park ),( Yerim Park ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1
Background/Aims:?There are currently no standardized guidelines for adequate determination of fasting period following gastric ESD. The aim of this study was to determine the appropriate length of fasting period. Materials and Methods:?Enrolled patients were randomized into a short fasting group and a long fasting group. In the short fasting group, patients had been fasting until the next day after ESD. In the long fasting group, patients had been fasting until two days after ESD. A second-look endoscopy was performed immediately prior to starting diet. The primary end point was a measurement of discomfort related ESD after diet such as epigastric pain, heart burn, regurgitation, nausea and vomiting. Secondary end points included bleeding rate after diet, hospital stay, patient satisfaction and hemostasis upon second-look endoscopy. Results:?We analyzed data from 101 of 110 randomized patients. Both groups demonstrated similar baseline characteristics. There were no significant differences in reports of epigastric pain, heartburn, regurgitation, nausea, and vomiting after diet. Both group demonstrated similar hemostasis rates upon second-look endoscopy (26% vs. 31.4%, p=0.551) and bleeding rate (4% vs. 0%, p=0.149). The duration of hospital stay was significantly shorter in the short fasting group (4.12 days vs. 5.11 days, p<0.001), and patient satisfaction was greater (p=0.003) compared to the long fasting group. Conclusions:?The short fasting period does not cause discomfort related to ESD nor does it influence post ESD bleeding. Moreover, the short fasting protocol results in shorter hospital stays and greater patient satisfaction.
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Shin, Dong-Ho,Park, Kyung Woo,Koo, Bon-Kwon,Oh, Il-Young,Seo, Jae-Bin,Gwon, Hyeon-Cheol,Jeong, Myung-Ho,Seong, In-Whan,Rha, Seung Woon,Yang, Ju-Young,Park, Seung-Jung,Yoon, Jung Han,Han, Kyoo-Rok,Park The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.8
<P>This study compared two-stent strategies for treatment of bifurcation lesions by stenting order, 'main across side first (A-family)' vs 'side branch first (S-family). The study population was patients from 16 centers in Korea who underwent drug eluting stent implantation with two-stent strategy (A-family:109, S-family:140 patients). The endpoints were cardiac death, myocardial infarction (MI), stent thrombosis (ST), and target lesion revascularization (TLR) during 3 years. During 440.8 person-years (median 20.2 months), there was 1 cardiac death, 4 MIs (including 2 STs), and 12 TLRs. Cumulative incidence of cardiac death, MI and ST was lower in A-family (0% in A-family vs 4.9% in S-family, <I>P</I> = 0.045). However, TLR rates were not different between the two groups (7.1% vs 6.2%, <I>P</I> = 0.682). Final kissing inflation (FKI) was a predictor of the hard-endpoint (hazard ratio 0.061; 95% CI 0.007-0.547, <I>P</I> = 0.013), but was not a predictor of TLR. The incidence of hard-endpoint of S-family with FKI was comparable to A-family, whereas S-family without FKI showed the poorest prognosis (1.1% vs 15.9%, retrospectively; <I>P</I> = 0.011). In conclusion, 'A-family' seems preferable to 'S-family' if both approaches are feasible. When two-stent strategy is used, every effort should be made to perform FKI, especially in 'S-family'.</P>
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Dong-Ho Shin,Hyun-Jae Kang,Jae-Sik Jang,Keon-Woong Moon,Young Bin Song,Duk-Woo Park,Jang-Whan Bae,Juhan Kim,Seung-Ho Hur,Byung Ok Kim,Dong Woon Jeon,Donghoon Choi,Kyoo-Rok Han 대한심장학회 2019 Korean Circulation Journal Vol.49 No.12
Background and objectives: In this second report from Korean percutaneous coronary intervention (K-PCI) registry, we sought to describe the updated information of PCI practices and Korean practice pattern of PCI (KP3). Methods: In addition to K-PCI registry of 2014, new cohort of 2016 from 92 participating centers was appended. Demographic and procedural information, as well as in-hospital outcomes, of PCI was collected using a web-based reporting system. KP3 class C was defined as any strategy with less evidence from randomized trials and more aggressive for PCI than medical therapy or bypass-surgery. Results: In 2016, total 48,823 PCI procedures were performed at 92 participating centers. Mean age of the patients was 65.7±11.6 years, and 71.7% were males. Overall patient characteristics and PCI practices in 2016 were similar to those in 2014. The biggest change was the decrease in the in-hospital occurrence of myocardial infarction (MI;1.6%→0.7%, p<0.001). Many associations between PCI volumes and demographic/procedural characteristics observed in 2014 have disappeared. The median of door-to-balloon time was 62 minutes, and 83.3% of ST-elevation MI patients received primary PCI within 90 minutes, while the median of total ischemic time was 168 minutes and patients who had total ischemic time within 120 and 180 minutes were 29.1% and 54.1%, respectively. The proportion of KP3 class C cases in non-acute coronary syndrome patients decreased from 13.5% in 2014 to 12.1% in 2016 (p<0.001). Conclusions: In this second report from K-PCI registry, we described the current practices of PCI and changes from 2014 to 2016 in Korea.
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