긴촌충(廣節裂頭條蟲) 感柒의 一例

李駿商,林漢鍾,鄭啓憲 순천향대학교 1980 논문집 Vol.3 No.3

韓國에서의 긴촌충(廣節裂頭條史) 感染例는 日制時 慶南地方 住民들의 大便檢査 증에 史卵이 觀索되었다는 報告가 있었고, 患者로부터 成忠을 얻어 報告한 例는 趙等(1971)이 報告한 1例 뿐이었다. 著者들은 14歲의 韓國少年으로부터 길이 685cm의 頭節이 없는 史體를 얻었다. 治療藥製는 Bithionol이었다. 忠體를 形態學論으로 檢討한 바 Diphyllobothrium latum(Linnaeus, 1758) Luhe, 1910으로 同定되었다. 患者는 그때까지 外國을 旅行한 經驗이 없었으며 市中에서 生鮮膾률 먹거나 약수터 또는 溪流의 물을 마신 記憶이 없고 더우기 뱀이나 개구리를 生食한 經驗은 전혀 없다고 한다. 다만 그는 本硏究室을 찾기 1年前 그의 父親을 따라 浦項으로 바다낚시를 간 일이 있으며 그곳에서 낚아 올린 농어( 魚)를 謄로 먹은 經驗이 있다고 하였다. 그러므로 本例의 感染源은 魚일 가능성이 많으며 分明한 것은 國內의 土着感染이란 점이다. , 國內에서 수시로 報告되는 sparganum症의 例로 보거나 中間宿主의 役割을 할 수 있다고 思料되는 甲穀類 및 魚類에 대한 報告와 韓國海洋의 魚類分布로 보아 韓國에서의 廣節裂頭條忠 感染率은 窓外로 높을지도 모른다. A case of Diphyllobothrium latum infection was recorded. A 14-year-old Korean boy was infected with this tape worm and treated with bithionol orally. An incomplete strobila without scolex and neck parts was collected. It was identified as D.latum on the basis of morpho1ogical characteristics. The most probab1e source of infection is autochthonous according to the past history of the patient. This is the second record of Diphyllo-bothrium latum infection in Korea which was verified with the recovery of the adult worm.

에어포일의 양력증가를 위한 경계층 제어에 관한 실험적 연구

박계향,유상신,이봉준 한국 항공대학교 항공산업기술연구소 1997 航空宇宙産業技術硏究所 硏究誌 Vol.7 No.-

본 연구에서는 2차원 NACA 0024 에어포일에서 앞전 슬릿흡입과 riblets이 경계층 구조에 미치는 영향에 대하여 실험적으로 고찰 하였다. 슬릿흡입(slit suction)에서 슬릿의 위치와 수, 자유흐름속도, 받음각 그리고 슬릿 흡입량이 중요한 변수이다. 슬릿흡입과 리블렛(riblets)이 설치된 2차원 에어포일의 양력계수와 항력계수 실험결과를 제시하였다. 에어포일에 슬릿 흡입을 적용하면 양력계수 항력계수가 다같이 증가된다. 원형 리블렛이 설치된 에어포일 모델에서는 양력계수가 증가되고 항력계수가 감소된다. An exprimental study on manipulation of the boundary layer of the two-dimensional NACA 0024 airfoil with slit suctions and riblets is presented. The slit locations, the number of slits, free stream velocity, angle of attack and the suction rate coefficient are variables. Exprimental results for the lift and drag coefficients of the two-dimensional airfoil with slit suctions and riblets are presented. When the slit suction is applied on the airfoil wall the lift and drag coefficients increase. Airfoil model with round riblets on the wall shows an increase of the lift coefficients and a decrease of the drag coefficient.

수술적으로 치료한 통증을 동반한 흉추부의 후외상성 Schmorl씨 결절 : 2례 보고 Report of Two Cases

신병준,이재철,송화용,정석봉,권계원,조영일,김연일 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Study Design : Two patients who had painful Schmorl's node at thoracic level from acute trauma were adopted and taken operation for its treatment Objectives : To document the effect of operation for the treatment of painful Schmorl's node at thoracic level summary of background data : Schrmorl's nodes are common spinal lesion generally believed to be asymptomatic, but in some cases there were painful symptom by Schmorl's node. This case report is to explain the effect of operative treatment for the painful Schmorl's node. Methods : Two patients were adopted who had traumatic painful Schmorl's node at thoracic level for our case report. They were treated conservative methods at first but it's effect were poor, so they were taken anterior decompression and fusion, and checked back pain symptom. Result : In all two patients, the symptom of back pain by Schmorl's nodes at thoracic level was almost subsided. conclusion : For the treatment of traumatic painful Schmorl's node, most of surgeon says that conservative treatments were treatment of choice, but operative treatments are also benefit to subsidence of back pain by Schmorl's node.

저밀도 폴리에틸렌에서 도데실 알콜의 혼합량에 따른 트리이 현상 변화에 관한 연구

金正洙,李昌熙,李桂安,金相準 弘益大學校 1990 弘大論叢 Vol.22 No.2

For the purpose of deriving a method of inhibiting tree growth, dodecyl alchol( ?? ) is mixed with low density polyethylene(LDPE) by four different concentration, i.e., 2, 5, 8, 10%. Then under the environment of keeping to apply a.c., 15[kv], the time on which the first tree phenonenum will be reached, is observed. It is resulted that, on the condition of being within 8%, the more the mixing quantity be, the longer the tree inception time is, on the other hand, through to 10%, the time get increased quite slowly. Thus, we take samples mixed with 10% dodecyl alcohol in LDPE. After the initial tree is generated to the point of 300[㎛] under the bias, the bias would abruptly be dropped to 7.5[kv]. After that time, without changing the applying voltage, it is also investigated that the extinguishing time interval gets shorter on the following sequence of the solid state, the freezing, point, and the liquid state, in trun.

진균 세포벽 형성 저해물질 생성 Streptomyces속 세균의 분리 및 수리동정

서원나,박정희,이지영,김인섭,이계준,배무 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1

본 연구의 목적은 진균의 세포벽 합성을 저해하는 항진균 물질생성 방선균을 개발하는 데 있다. 다양한 환경으로부터 채취한 토양 시료로부터 방선균 선택 배지를 이용하여 860여 방선균을 선택적으로 분리하였다. 분리 균주 중 Penicillium cyclopium, Cryptococcus laurentii, Aspergillus flavus에 특이적 항균 활성 물질을 생산하는 균주 EMS4, EMP22, L234를 각각 선별하였다. 화학적 동정과 형태학적 동정을 통해 분리 균주들이 Streptomyces속 세균임을 알 수 있었다. 총 50개의 주군집, 34개의 부군집 형질을 분석하고, 이 실험 결과를 TAXON program에 적용하여 종의 수리동정을 실시하였다. 그 결과 분리균 EMS4는 Streptomyces의 제 61 주군집에 속하는 Streptomyces lavendulae의 한 균주로 동정되었고, EMP22는 제 1B 주군집에 속하는 S. willmorei의 한 균주로 동정되었으며, L234는 제 3 부군집의 S. aburaviensis의 한 균주로 동정되었다. The aim of the present research program wa to identify and develop stains of actinomycetes producing antifungal antibiotics which inhibit cell wall biosynthesis. 860 strains of Actionomycetes were isolated from various soil samples. Three isolates, EMS4, EMP22, and L234 were selected as the strains producing antifungal antibiotics inducing abnormal morphology against Penicillium cyclopium. Cryptococcus laurentii, and Aspergillus flavus, respectively. Taxonomic unit characters of the strains were tested and the data were analyzed numerically using TAXON program. EMS4, EMP22, and L234 were identified to be a member of Streptomyces lavendulae, Streptomyces willmorei, and Streptomyces aburaviensis, respectively.

진균 세포벽 형성 저해물질 생성 Streptomyces속 세균의 분리 및 수리동정

서원나,박정희,이지영,김인섭,이계준,배무 이화여자대학교 생명과학연구소 1996 생명과학연구논문집 Vol.7 No.-

본 연구의 목적은 진균의 세포벽 합성을 저해하는 항진균 물질생성 방선균을 개발하는 데 있다. 다양한 환경으로부터 재취한 토양 시료로부터 방선균 선택 배지를 이용하여 860여 방선균을 선택적으로 분리하였다. 분리 균주 중 Penicillum cyclopium, Cryptococcus laurentii, Aspergillus flavus에 특이적 항균 활성 물질을 생산하는 균주 EMS4, EMP22, L234를 각각 선별하였다. 화학적 동정과 형태학적 동정을 통해 분리 균주들이 Streptomyces속 세균임을 알 수 있었다. 총 50개의 주군집, 34개의 부군집 형질을 분석하고, 이 실험 결과를 TAXON program에 적용하여 종의 수리동정을 실시하였다. 그 결과 분리균 EMS4는 Streptomyces의 제 61 주군집에 속하는 Streptomyces lavendulae의 한 균주로 동정되었고, EMP22는 제 1B 주군집에 속하는 S. willmorei의 한 균주로 동정되었으며, L234는 제 3 부군집의 S. aburaviensis의 한 균주로 동정되었다. The aim of the present research program was to identify and develop strains of actinomycetes producing antifungal antibiotics which inhibit cell wall biosynthesis. 860 strains of Actinomycetes were isolated from various soil samples. Three isolates, EMS4, EMP22, and L234 were selected as the strains producing antifungal antibiotics inducing abnormal morphology against Penicillium cyclopium, Cryptococcus laurentii, and Aspergillus flavus, respectively. Taxonomic unit characters of the strains were tested and the data were analyzed numerically using TAXON program. EMS 4,EMP22, and L234 were identified to be a member of Streptomyces lavendulae, Streptomyces willmorei, and Streptomyces aburaviensis, respectively.

자외선 조사에 의한 인체 각질형성세포 세포고사 방어인자에 관한 연구

박수홍,박준홍,이종석,황규왕,김계정 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Back ground: Human skin is continuously exposed to UV irradiation. Ultraviolet irradiation of human skin cause sunburn cell which is relevant to the apoptosis of keratinocytes. In the epidermis, apoptosis inducing factors and anti-apoptotic factors probably exist to maintain the integrity of keratinocytes. Objective: The purpose of this study was to investigate the exsistence of apoptosis inducing factors and anti-apoptotic defence factors by evaluation of UV induced apoptosis in cultured human keratinocyte and other keratinocyte cell lines(A-431 cells, KB cells) and its susceptibility of UV induced apoptosis in various conditions. Method: In this study, the percentages of apoptosis, necrosis and cell viability of irradiated human keratinocytes and othe keratinocyte cell lines by MMT assay and AO/EO stain. The percentages of those were measured before UVB irradiation and 8, 24, 48 hours after UVB irradiation. Also, the same evaluations were performed with irradiated human keratinocytes cultured without growth factor and with enough growth factors, both results were compared with each other. And the effect of cycloheximide, a protein synthesis inhibitor was evaluated. Also that of aurintricarboxylic acid(ATA), an inhibitor of endonucleases which play an important role in inducing apoptosis of human keratinocytes was evaluated. Result: Human keratinocytes and other keratinocyte cell lines(A-431 cells, KB cells) were cultured in vitro developed maximal apoptosis 48 hours after irradiation, keratinocytes were more resistant to UV induced apoptosis than the others. The withdrawal of growth factors from keratinocyte and addition of cycloheximide decreased the cell survival rate following UV irradiation and increased the induction of apoptosis. And ATA inhibited UV induced apoptosis. Conclusion: These results indicate that human keratinocytes have both anti-apoptotic factors and apoptosis inducing factors to maintain the homeostasis. And survival signals mediated through growth factors or cellular proteins are responsible for the resistance to apoptosis observed in keratinocytes in vitro.

제한효소인 Sdi Ⅰ을 생성하는 Streptomyces 분리 균주의 수리동정

배무,서원나,송은숙,이계준 이화여자대학교 생명과학연구소 1994 생명과학연구논문집 Vol.5 No.-

제한효소인 Sdi I을 생산하는 한 균주(Streptomyces sp.264)를 토양으로부터 분리하여 형태적 관찰 및 수리동정을 실시하였다. 50여개의 분류 단위 형질을 분석하였고, 이 실험 결과를 TAXON program에 적용하여 종의 수리동정을 실시하였다. 그 결과 분리균 sp.264는 Streptomyces의 제 19주군집에 속하는 Streptomyces diastatochromogenes의 한 균주로 동정되었다. Numerical identification was applied for Streptomyces sp.264, an isolate producing a new restriction endonuclease Sdi I. The restriction enzyme would appear to be an isoschisomer of Xho I. Fifty taxonomic unit characters were tested and the data obtained were analyzed numerically by using the TAXON program. The isolate was identified to be the jamor cluster 19 of Streptomyces and best matched to S. diastatochromogenes. It was, therefore, concluded that the isolate was identified to be a member of Streptomyces diastatochromogenes.

제한효소 SacⅡ의 Isoschizomer인 SexⅢ를 생성하는 토양 Streptomyces 균주의 수리 동정

배무,서원나,박정옥,김형태,이계준 이화여자대학교 생명과학연구소 1993 생명과학연구논문집 Vol.4 No.-

제한효소인 SexⅢ을 생성하는 Streptomyces속의 한 균주(Streptomyces sp.58)를 토양으로부터 분리하여 형태적 관찰 및 수리동정을 실시하였다. 50여개의 분류 단위 형질을 분석하였고 이 실험 결과를 TAXON program에 적용하여 종의 수리 동정을 실시하였다. 그 결과 분리균은 Streptomyces의 제5주군집에 속하는 것으로 나타나 Streptomyces exfoliatus의 한 균주로 동정하였다. Numerical identification was carried out for an isolate of Streptomyces sp. 58 producing a new restriction endonuclease SexⅢ. Fifty taxonomic unit characters were tested and the data were analyzed numerically using the TAXON program. The isolate was identified to the major 5 or Streptomyces. Therefore, it was concluded that the isolate was identified to be a member of Streptomyces exfoliatus.

응급실을 내원한 65세 이상 노인 환자의 분석

김진년,김태훈,강양욱,오명,김상철,김성훈,권계형,남홍우,이홍순,유형준 대한노인병학회 2001 대한노인병학회지 Vol.5 No.3