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      • 인터네트워크에서 트래픽 분석에 관한 연구

        구현회 배화여자대학 1999 培花論叢 Vol.18 No.-

        This thesis presented an analysis of the packet flowing in Kreonet, thereby considering the spatial concept of the network. This study provided an analysis as to whether the packet information flowing through the inter-network is operated in the real form and the amount of packet, and the study also analysed of the packet information, so that it may become important information in designing for the interlock between the ever-increasing amount of information and network. And it is expected that the study, which has been analyzed in this thesis, will not contribute to prepare for the network environment only when the technical power of the system (bridge, gateway, etc) to be developed in the future is improved and a diversity of information is transmitted as comprehensive information communications in an integreated way.

      • 신경학적 증상을 동반한 Henoch-Scho"nlein 자반증 1례

        어성훈,구현회,하태선 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.1

        Henoch-Schonlein 자반증(HS 자반증)의 원인은 아직 잘 알려지지 않았으나, IgA를 함유하는 면역 복합체가 침착하는 전신 질환으로 세정맥, 세동맥, 모세 혈관과 같은 작은 혈관의 손상을 초래하는 전신성 혈관장애로 알려져 있다. 모든 연령에서 발생 할 수 있으며, 소아가 성인에 비하여 더 많이 발생하고 피부, 복부, 관절, 신장에서 증상이 나타나며, 뇌신경학적 증상은 드문 것으로 알려져 있으며 심각한 결과를 초래할 수 있다. 저자들은 전형적인 HS 자반증의 환아에서 뇌신경학적 증상을 보인 1례를 문헌 고찰과 함께 보고하는 바이다. Henoch-Schonlein purpura(HSP) is a multisystem disorder affecting predominantly the skin, joints, gastrointestinal tract and kidneys, although other organs are rarely involved. Neurological complications are rare during the course of HSP. We report a 8-year-old boy with HSP who presented with neurologic abnormality (neck stiffness, headache, vomiting, fever, increased WBC in cerebrospinal fluid, which dramatically resolved with clinical improvement.

      • 接觸酸化法을 利用한 LAS 除去效率에 關한 硏究

        오종민,구태회,진현오,윤동선,박재영 경희대학교 환경연구소 1997 環境硏究 論文集 Vol.7 No.-

        This study was performed to know LAS concentration in the small urban stream and estimate the LAS removal efficiency when apply to natural purification method with variable media. When we used gravel and concrete as media, the average LAS concentration of influent was 819.7㎍/ℓ (112.0 ∼ 1671.0 ㎍/ℓ). The average LAS concentration of effluent gravel media reactor was 58.5 ㎍/ℓ (0 ∼ 158.4 ㎍/ℓ) and average removal efficiency was 93.8%. The average LAS concentration of effluent concrete media reactor was 33.1 ㎍/ℓ (0 ∼ 136.8 ㎍/ℓ) and average removal efficiency was 96.1%. And when we used tire and scrubber, the average LAS concentration of influent was 693.7 ㎍/ℓ (241.5 ∼ 1330.3 ㎍/ℓ). The average LAS concentration of effluent tire media reactor was 88.4 ㎍/ℓ (47.8 ∼ 131.8 ㎍/ℓ) and average removal efficiency was 83.9%. The average LAS concentration of effluent scrubber media reactor was 26.1 ㎍/ℓ(0 ∼ 58.9 ㎍/ℓ) and average removal efficiency was 95.3%.

      • KCI등재후보

        Staphylococcus lugdunensis에 의한 감염성 심내막염 1예

        최성호,박현구,변승운,구동회,강호석,장항제,김양수,우준희,김영휘,최상호 대한감염학회 2006 감염과 화학요법 Vol.38 No.5

        Staphylococcus lugdunensis is a coagulase-negative staphylococcus (CNS) that is commonly found on the human perineal skin. Contrary to other CNS, S. lugdunensis is a rare contaminant in cultures and has the potential to cause clinically significant infections, including infective endocarditis. Infective endocarditis due to S. lugdunensis have been known to resemble endocarditis due to S. aureus because of its aggressive clinical course and high mortality. We report a case of infective endocarditis caused by S. lugdunensis in a 21-year-old woman. She was cured of the infection with surgical and antibiotic therapy. S. lugdunensis에 의한 감염성 심내막염은 국내에서보고가 없었던 매우 드물지만 다양한 합병증과 높은 사망률을 보이는 감염증이다. 저자들은 S. lugdunensis가 수술적 치료와 항생제 치료로 완치된 감염성 심내막염 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

      • 만성 간질환에서 혈청 Type Ⅳ Collagen 측정의 의의

        이헌영,김성걸,정현용,구선회,박종우,강대영 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

        To evaluate the clinical significance of serum type N collagen levels in patients with various liver diseases, serum type IV collagen levels were measured by one-step sandwich enzyme immunoassay using monoclonal antibodies in 80 patients from December 1993 to December 1994 at Chung Nam National University Hospital. The results were as follows : 1. Mean age of patients was 45 years. Men was 2.1 times more than women. 2. Compared to 15 normal controls(159.9±34.0 ng/ml), serum type IV collagens were significantly elevated in patients with chronic hepatitis (254.5±158.0 ng/ml), liver cirrhosis(281.0±195.7 ng/ml) and hepatocellular carcinoma(420.5±241.4 ng/ml) (p<0.005). 3. Serum type IV collagen levels were increased without significance in patients with alcholic liver cirrhosis(331.6±244.5 ng/ml) compared to non-alcholic cirrhosis(230.4±117.8 ng/ml. p>0.05). 4. The serum levels of type IV collagen were not correlated with the levels of alanine amino-trnasferase(ALT), aspartate aminotransferase(AST) and alkaline phosphatase(ALP). The results suggest that the serum type IV collagen levels correlate well with the degree of progression of chronic liver diseases. Therefore the measurement of serum type IV collagen is relatively simple and useful method to reflect the progression of chronic liver diseases.

      • SCOPUSKCI등재

        안지오텐신 2의 사구체 상피세포 ZO-1에 대한 영향

        구현회 ( Hyun Hoe Koo ),하태선 ( Tae Sun Ha ) 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.5

        Purpose : Angiotensin II plays a potent role in renal injury not only by vasoconstrictive effects but also by biochemical effects. We investigated the effect of angiotensin II on ZO-1 (zonular occludens-1), a component of the slit diaphragm domain connecting slit diaphragm structure and actin cytoskeleton, in the glomerular epithelial cells (podocytes) for the glomerular damage. We tried to find that this effect could be prevented by losartan, an angiotensin II type 1 receptor blocker. Methods : Glomerular epithelial cells were treated with various concentrations of angiotensin II and losartan. The distribution of ZO-1 was observed by confocal microscope and the change of ZO-1 expression was measured by Western blotting and RT-PCR. Results : The intensities of fluorescences and bands of ZO-1 protein were decreased by angiotensin II in a dose-dependent manner by confocal microscopy and Western blot analysis, respectively. ZO-1 also moved from peripheral to inner cytoplasm and lost its linear pattern. These distributional changes of ZO-1 protein by angiotensin II were reversed by losartan in a dose-dependent manner. Angiotensin II reduced the amount and mRNA expresssion of ZO-1 which were also reversed by losartan. Conclusion : Angiotensin II decreases the amount of ZO-1 protein and changes its localization through angiotensin II type 1 receptor. These findings suggest that angiotensin II-added condition induces the cytoplasmic translocation and suppresses the production of ZO-1 in podocytes at transcriptional level, and could be prevented by angiotensin receptor antagonists.

      • KCI등재후보

        간질 중첩증으로 내원한 환아에서 발견된 뇌 정맥 기형 1례

        구현회(Hyun Hoe Koo),김원섭(Won Seop Kim),배일헌(Il Hun Pae) 대한소아신경학회 2001 대한소아신경학회지 Vol.9 No.2

        저자들은 출생 후 정상 발달을 보였고 경련의 과거력이 없었던 4세 환아에서, 임상적으로 3시간 이상 지속되는 간질 중첩증을 보여 시행한 뇌파상 전두부와 측두부에서 때때로 나타나는 극파와 뇌혈관 조영술과 뇌 자기 공명 영상에서 정맥기형을 진단한 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Venous malformations has been shown to be the most common intracranial vascular malformation autopsy and clinical series. Cerebral venous malformation is associated with different frequnecies of epileptic seizures. Only in about 25% of cases are venous malformation diagnosed because of the occurrence of epileptic seizures. We report a case of 4 year-old female patient with status epilepticus caused by venous angioma in the right temporal lobe of the brain.

      • KCI등재후보

        양측 시상, 피개를 침범한 후 운동 장애를 남긴 영아 2례

        구현회(Hyun Hoe Koo),김원섭(Won Seop Kim),차상훈(Sang Hun Cha) 대한소아신경학회 2001 대한소아신경학회지 Vol.9 No.2

        저자들은 출생 후 정상 발달을 보였고 경련의 과거력이 없었던 각 5개월과 11개월된 영아들에서 발생한 양측 시상, 피개를 침범한 급성 뇌병증 후 운동장애를 남긴 2례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Acute encephalopathy with thalamotegmental involvement occurs in infants and young children and is thought to be a postviral or postinfectious brain disease. This disease is preceded for several days by fever and symptoms of upper respiratory infection. The symptoms are followed by the rapid evolution of stupor and coma, associated with generalized seizures and decerebrate rigidity. In this disease, the computed tomography (CT) or brain magnetic resonance imaging demonstrate symmetrical focal lesions in the thalami and brainstem tegmentum. We report two cases of acute encephalopathy with thalamotegmental involvement and remaining motor dysfunction in infants.

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