유역수문모형과 빈도해석을 이용한 충주댐 상류유역 지하수 개발가능량의 평가

이정은,김남원,정일문,이정우,Lee, Jeong-Eun,Kim, Nam-Won,Chung, Il-Moon,Lee, Jeong-Woo 대한자원환경지질학회 2008 자원환경지질 Vol.41 No.4

지하수 함양은 수문학적으로 복잡한 프로세스로서 강우의 빈도, 강도, 지속시간, 계절적 분포 뿐 아니라 온도, 습도, 풍속과 같은 기상인자, 그리고 지하수위 상부에 존재하는 토양 및 암반층의 특성과 깊이, 지표의 지형과 식생분포 및 토지이용과도 관련된다(Memon, 1995). 이러한 지하수 함양량의 영향요소를 반영하기 위해 연속 유역수문모형인 SWAT-K를 이용하여 충주댐 상류 유역의 지하수 함양량을 계산하였다. 우리나라에서는 10년 빈도 갈수시 강수량에 함양계수를 곱하여 지역별 개발가능량을 산정한다. 본 연구에서는 빈도해석을 통한 10년 빈도 갈수시의 함양량을 추정, 이를 기존 개발가능량 값과 비교, 검토하는 방식으로 충주댐 상류유역의 지하수 개발가능량을 평가하였으며, 이같은 계산 절차를 통해 지하수 개발가능량을 산정하는 기존 절차의 문제점을 제시할 수 있었다. Memon(1995) pointed out that the groundwater recharge from the precipitation is affected by various factors such as the occurrence, intensity, duration, and seasonal distribution of rainfall; air temperature, humidity, and wind velocity; the character and thickness of the soil layer above the water table; vegetated cover, soil moisture content, depth to the water table, topography; and land use. To reflect above factors, groundwater recharge in Chungju basin is computed by using the SWAT-K which is a longterm continuous watershed hydrologic model. Frequency analysis is adopted to evaluate the existing values of potential amount of groundwater development which is made by the 10 year drought frequency rainfall multiplied by recharge coefficient. In this work, the recharge rates of 10 year drought frequency in subbains were computed and compared with the existing values of potential amount of groundwater development. This process could point out the problems of existing precesses used for computing potential amount of groundwater development.

직장인 스트레스 반응 척도 개발 및 타당화 연구

이정은,최보라,정영은,송광헌,강민재,채정호,Lee, Jeong Eun,Choi, Bora,Jung, Young-Eun,Song, Gary,Kang, Min Jae,Chae, Jeong-Ho 대한불안의학회 2012 대한불안의학회지 Vol.8 No.2

Objectives : The purpose of this study was to develop an employee's stress response scale (ESRS) and examine its validity and reliability. Methods : The study was conducted as follows : item generation, and test of validity and reliability. Items were developed via literature review, review of instruments, and data acquired from email-survey of counselors in the field of Employee Assistance Program (EAP). In order to test validity and reliability, data were collected from 400 employees. Results : The result of exploratory factor analysis of ESRS suggested 4 factor structures (work-related, anger, somatization, depression & anxiety) with a total of 25 items. ESRS showed a relatively strong positive correlation with Hospital Anxiety-Depression scale (HAD), Perceived Stress Scale (PSS), and Psychological Wellbeing Index (PWI), which showed ESRS had high convergent validity. Cronbach's ${\alpha}$ and test-retest reliability was .95 and .610 respectively. Conclusion : The ESRS is reliable and valid brief scale for measuring stress responses of employees. This scale would be useful in quantitatively evaluating job stress in workplace.

세상의 빛을 모든 이들에게

이정은,Lee, Jeong-Eun 한국가톨릭의료협회 2002 한국가톨릭병원협회지 Vol.32 No.-

북방수염하늘소(Monochamus saltuarius), 솔수염하늘소(Monochamus alternatus), 털두꺼비하늘소(Moechotypa diphysis) 성충의 표피탄화수소 비교

이정은,김은희,윤창만,김길하,Lee, Jeong-Eun,Kim, Eun-Hee,Yoon, Chang-Mann,Kim, Gil-Hah 한국응용곤충학회 2010 한국응용곤충학회지 Vol.49 No.3

북방수염하늘소, 솔수염하늘소, 털두꺼비하늘소 성충 암·수의 표피탄화수소를 GC와 GC-MS로 분석하고 비교하였다. 북방수염하늘소와 솔수염하늘소는 소나무재선충병의 대표적 매개충이지만 같은 과에 속한 털두꺼비하늘소는 그렇지 않다. 이들은 표피탄화수소 사슬을 다르게 가지고 있는데, 북방수염하늘소의 표피탄화수소 사슬은 $C_{23-35}$, 솔수염하늘소는 $C_{25-32}$, 그리고 털두꺼비하늘소는 $C_{23-29}$로 종간 차이를 보였다. 주 구성성분의 암 수간 차이에서 함량에 대한 차이는 있었지만, 조성에 대한 차이는 없었다. 북방수염하늘소는 n-pentacosane > n-nonacosane > n-heptacosane, 솔수염하늘소는 n-nonacosene > n-pentacosane > n-nonacosane을 가장 많이 포함하고 있었으며, 털두꺼비하늘소는 n-heptacosane > 13-methylheptacosane > 3-methylheptacosane을 가장 많이 포함하고 있는데 반해 n-nonacosene, n-pentacosane의 함량은 적었다. 3종하늘소 표피의 대부분은 n-alkane인 포화탄화수소로 이루어져 있고(40.2 - 65.7%) 그 다음으로, 북방수염하늘소와 솔수염하늘소는 하나 또는 두 개의 이중결합을 갖는 olefins > monomethylalkanes 순이었다. 이와 달리, 털두꺼비하늘소는 monomethylalkanes > olefins 순으로 함량에 차이가 있었다. Cuticular hydrocarbons (CHCs) of the pine sawyer (Monochamus saltuarius), Japanese pine sawyer (M. alternatus) and oak longicorn beetle (Moechotypa diphysis) were analyzed by GC, GC-MS and compared. Monochamus beetles are typical vectors of pine wilt disease but Moechotypa diphysis, which belongs to the same family, is not. They possess different CHCs in carbon number: 23-25 in M. saltuarius, 25-32 in M. alternatus, and 23-29 in M. diphysis. In comparison to inter-species, these three species of adult beetles have different numbers and chains of constituents of CHCs. In comparison between male and female in intra-species, the quantities of CHCs show the difference but constituents are not. Major constituent of M. saltuarius were analyzed as n-pentacosane > n-nonacosane > n-heptacosane; those of M. alternatus were n-nonacosene > n-pentacosane > n-nonacosane; and those of M. diphysis were n-heptacosane > 13-methylheptacosane > 3-methylheptacosane. From the body surface, most saturated carbohydrates of 3 species beetles are composed of n-alkane (40.2 - 65.7%) and followed by olefines > monomethylalkanes that one or two double bonds in M. saltuarius and M. alternatus. Otherwise, M. diphysis have the difference in order of monomethylalkanes > olefins.

미륵사지 석탑 축기부 토층의 조성분석을 통한 제작기법 해석

이정은,이찬희,이동식,Yi, Jeong-Eun,Lee, Chan-Hee,Lee, Dong-Sik 대한자원환경지질학회 2012 자원환경지질 Vol.45 No.3

익산 미륵사지 석탑은 백제시대의 석탑으로 미륵사터에 세워진 탑 중 유일하게 현존하는 국보 제11호이다. 이 석탑은 이미 부분적으로 원형을 상실한 상태로서 현재는 완전히 해체되어 복원을 앞두고 있다. 이 연구에서는 석탑의 지반에 대한 판축기술 및 제작기법을 해석하기 위해 사지 조성층, 석탑 축기부 및 기단 조성층에 사용된 토층을 층위별로 구분하여 물리적, 재료학적 및 지구화학적 특성 분석을 수행하였다. 또한 미륵사지 주변에 분포하는 지반 토양 5점을 선정하여 석탑 판축에 사용된 토층과의 비교연구를 통하여 상호간의 동질성을 해석하였다. 이 결과, 석탑의 판축에 사용된 모든 토층에서 인위적 첨가물은 확인되지 않았다. 또한 주변 지역의 토양과 물리적, 광물학적 및 지구화학적 특성이 동일한 것으로 확인되었다. 따라서 미륵사지 석탑의 지반은 특별한 정선과정 없이 주변 지역의 토양을 사용하여 축조한 것으로 해석된다. The Mireuksaji stone pagoda is constructed Baekje Period in the 7th century which is located in Iksan, Korea. This stone pagoda designated by National Treasure No. 11 is the only remaining pagoda. This pagoda has lost the original form in part and the whole stonework wase dismantled. Work for the restoration is currently in progress. This study was divided into soil strata such as construct layer of the temple site, foundation layer of the pagoda basement, and construct layer of the stylobate by stratum to interpretation the skill of rammed earth and making techniques. The of physical, mineralogical and geochemical characteristics of soil samples were identified. Five pieces of soil in and around the Mireuksaji temple site was selected for the comparative study to interpretate the mutual homogeneity among soil stratum. As a result, artificial addition has not been identified in all soil samples using rammed earth. The soils used for the basement of the stone pagoda (construct layer of the temple site, foundation layer of the pagoda basement, construct layer of the stylobate) were confirmed to be the same origin as soil in and around Mireuksaji temple site. Thus these results indicate that the basement of the pagoda was constructed using soils in and around the Mireuksaji temple site without work as careful selection.

Phase II Study of Induction Irinotecan + Cisplatin Chemotherapy Followed by Concurrent Irinotecan + Cisplatin Plus Twice-Daily Thoracic Radiotherapy

이정은,박희선,정성수,김주옥,조문준,김진환,이충식,김선영,Lee, Jeong Eun,Park, Hee Sun,Jung, Sung Soo,Kim, Ju Ock,Cho, Moon June,Kim, Jin Hwan,Lee, Choong Sik,Kim, Sun Young The Korean Academy of Tuberculosis and Respiratory 2007 Tuberculosis and Respiratory Diseases Vol.63 No.2

배경: Irinotecan hydrochloride는 topoisomerase I inhibitor로서 소세포 폐암에 효과적인 약제로 알려져 있다. Irinotecan은 cisplatin과 더불어 방사선감작물질로 작용하기도 한다. 본 연구는 이전에 치료받은 경험이 없는 제한성 병기의 소세포 폐암 환자에서 irinotecan과 cisplatin(IP)의 방사선 동시화학요법의 효과를 평가하기 위하여 시행되었다. 방법: 2002년 12월부터 2004년 11월까지 충남대학교 병원에서 새로이 제한성 병기의 소세포 폐암으로 진단된 24명의 환자들을 대상으로 하였다. Irinotecan $60mg/m^2$을 제 1일과 제 8일째 투여하였고 cisplatin $60mg/m^2$을 제 1일째 투여하였으며 매 3주 간격으로 시행되었다. 제 3차 항암화학요법을 시작하는 날과 동시에 과다 분할방사선 치료(twice-daily thoracic irradiation; 45 Gy total)을 시작하였다. 예방적 전 뇌 방사선 조사(Prophylactic cranial irradiation)가 방사선 동시화학요법이 끝난 후 완전반응(complete response)을 나타낸 환자에서 시행되었다. 제 2차 항암요법과 제 6차 항암요법이 끝난 후에 흉부 전산화 단층촬영과 기관지경 등을 통한 병기의 재평가가 이루어졌다. 결과: 병기의 재평가는 19명의 환자에게 이루어졌다. 중앙 추적관찰기간은 12.5개월이고 전체 99회의 항암치료가 시행되었다. 평균 한 환자당 5.2회의 항암치료가 시행되었다. 실제 용량강도는 cisplatin $19.6mg/m^2$/week과 irinotecan $38.2mg/m^2$/week이었다. 9명의 환자가 완전반응을 보였고 10명의 환자가 부분반응(partial response)을 보여서 전체 반응률은 95%였다. 3에서 4도의 혈액학적 독성은 백혈구 감소증(35% of cycles), 빈혈(7% of cycles), 혈소판 감소증(7% of cycles) 등으로 나타났다. 3에서 4도의 비 혈액학적 독성은 설사(5% of cycles)였다. 3에서 4도의 방사선 식도염(10% of patients)을 제외하고는 과다 분할 방사선 치료를 이용한 방사선 동시 화학요법의 기존의 방법과 독성 면에서는 큰 차이가 없었다. 치료와 관련된 사망은 관찰되지 않았다. 평가가 가능한 환자들에서 1년 생존율과 2년 생존율은 각각 89% (16/18)와 47% (9/18)였다. 결론: 3주 간격으로 시행된 irinotecan과 cisplatin을 이용한 과다분할 방사선 동시 요법은 제한성 병기의 소세포 폐암 환자에서 부작용은 높지 않으면서 효과적인 치료법으로 고려될 수 있을 것이다. Background: Irinotecan hydrochloride, a topoisomerase I inhibitor, is effective against small-cell lung cancer. Irinotecan also can act as a potential radiation sensitizer along with cisplatin. To evaluate efficacy and toxicity of irinotecan plus cisplatin (IP) with concurrent thoracic radiotherapy, we conducted a phase II study of IP followed by concurrent IP plus hyperfractionated thoracic radiotherapy in patients with previously untreated limited-stage small-cell lung cancer. Methods: Twenty-four patients with previously untreated small-cell lung cancer were enrolled onto the study since November 2004. Irinotecan $60mg/m^2$ was administered intravenously on days 1 and 8 in combination with cisplatin $60mg/m^2$ on day1 every 21 days. From the first day of third cycle, twice-daily thoracic irradiation (total 45 Gy) was given. Prophylactic cranial irradiation was given to the patients who showed complete remission after concurrent chemoradiotherapy. Restaging was done after second and sixth cycle with chest CT and/or bronchosocpy. Results: Up to November 2004, 19 patients were assessable. The median follow-up time was 12.5 months. A total of 99 cycles (median 5.2 cycles per patient) were administered. The actual dose intensity values were cisplatin $19.6mg/m^2$/week and irinotecan $38.2mg/m^2$/week. Among the 19 patients, the objective response rate was 95% (19 patients), with 9 patients (47%) having a complete response (CR). The major grade 3/4 hematological toxicities were neutropenia (35% of cycles), anemia (7% of cycles), thrombocytopenia (7% of cycles). Febrile neutropenia was 4% of cycles. The predominant grade 3/4 non-hematological toxicities was diarrhea (5% of cycles). Toxicities was not significantly different with concurrent administration of irinotecan and cisplatin with radiotherapy, except grade 3/4 radiation esophagitis (10% of patients). No treatment-related deaths were observed. The 1-year and 2-year survival rate of eligible patients was 89% (16/18) and 47% (9/18), respectively. Conclusion: Three-week schedule of irinotecan plus cisplatin followed by concurrent IP plus hyperfractionated thoracic radiotherapy is an effective treatment for limited disease small-cell lung cancer, with acceptable toxicity.

지하공간 안전성 향상를 위한 개선방안에 대한 연구

이정은,황현숙,김창수,Lee, Jeong-Eun,Hwang, Hyeon-Suk,Kim, Chang-Su 한국멀티미디어학회 2008 한국멀티미디어학회지 Vol.12 No.1

극저온 정제시스템의 품질관리를 위한 SF₆ 가스 분석방법 개선

이정은,조민,이원석,Lee, Jeong Eun,Cho, Min-ho,Lee, Won Seok 한국전력공사 2022 KEPCO Journal on electric power and energy Vol.8 No.1

Because sulfur hexafluoride(SF₆) is classified as one of the six major greenhouse gases, SF₆ handling in power plant such as recovery, purification, and reuse is considered to be important. KEPCO has focused to develop the advanced recovery and purification technology of SF₆ reuse. SF₆ analysis includes the on-site analyses and on-line analyzer; i.e., (1) on-site analysis has an error rate of ±0.5% and (2) on-line analysis has an error rate of ±0.1%, which is possible to adjust operating conditions and to make the work more conveniently by analyzing SF₆ concentration before and after purification step. This paper presents an online analysis method in the SF₆ purification and reuse system. In addition, the analysis results and quality guarantees for each section of the analysis system were presented.

Si 나노입자에서 shell이 전기화학적 특성에 미치는 영향

이정은,구정분,장보윤,김성수,Lee, Jeong-eun,Koo, Jeong-boon,Jang, Bo-yun,Kim, Sung-Soo 한국전기전자재료학회 2016 전기전자재료학회논문지 Vol.29 No.4

Effects of $SiO_x$ or C shells on electrochemical properties of Si nanoparticles were investigated. $SiO_x$ shells with thickness of 10~15 nm were formed on homogeneously crystalline Si nanoparticles. Incase of Si-C nanoparticles, there were 30~40 layers of C with a number of defects. Li-ion batteries were fabricated with the above-mentioned nanoparticles, and their electrochemical properties were measured. Pristine Si shows a high IRC (initial reversible capacity) of 2,517 mAh/g and ICE (initial columbic efficiency) of 87%, but low capacity retention of 22%, respectively. $SiO_x$ shells decreased IRC (1,534 mAh/g) and ICE (54%), while the retention increased up to 65%, which can be explained by irreversible phases such as $LiO_2$ and $Li_2SiO_3$. C shells exhibited no differences in IRC and ICE compared to the pristine Si but an enhanced retention of 54%, which might be from proper defect structures.

음이온성 지질을 포함한 지질나노입자의 제조 및 물리적 특성

이정은,김은혜,임덕휘,정석현,정규성,신병철,Lee, Jung-Eun,Kim, Eun-Hye,Lim, Deok-Hwi,Jung, Suk-Hyun,Jeong, Kyu-Sung,Shin, Byung-Cheol 대한화학회 2008 대한화학회지 Vol.52 No.3