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      • KCI등재

        Open Posterior Approach versus Arthroscopic Suture Fixation for Displaced Posterior Cruciate Ligament Avulsion Fractures: Systematic Review

        Jae­Gwang Song,Kyung Wook Nha,이세원 대한슬관절학회 2018 대한슬관절학회지 Vol.30 No.4

        Purpose: To compare the clinical outcomes between the open posterior approach and arthroscopic suture fixation for displaced posterior cruciate ligament (PCL) avulsion fractures.Methods: A literature search was performed on MEDLINE, EMBASE, and the Cochrane Library databases. The inclusion criteria were as follows: papers written in English on displaced PCL avulsion fractures, clinical trial(s) with clear description of surgical technique, adult subjects, a follow­up longer than 12 months and modified Coleman methodology score (CMS) more than 60 points.Results: Twelve studies were included with a mean CMS value of 72.4 (standard deviation, 7.6). Overall, 134 patients underwent the open posterior approach with a minimum 12­month follow­up, and 174 patients underwent arthroscopic suture fixation. At final follow­up, the range of Lysholm score was 85–100 for the open approach and 80–100 for the arthroscopic approach. Patients who were rated as normal or nearly normal in the International Knee Documentation Committee subjective knee assessment were 92%–100% for the open approach and 90%–100% for the arthroscopic approach. The range of side­to­side difference was 0–5 mm for both approaches.Conclusions: Both arthroscopic and open methods for the treatment of PCL tibial­side avulsion injuries resulted in comparably good clinical outcomes, radiological healing, and stable knees.

      • 여성생식계 상피세포에서 Glutathione S-Transferase 출현도에 관한 면역조직화학적 관찰

        송계용,김석중,김미경,박용욱,유재형,박상철 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.2

        Both placental form (GST-Pi) and basic form (GST-L) of glutathione S-transferase were studied in the epithelium of normal, tumor and tumor like lesions of female genital system. The results obtained were as follows : 1. Staining reaction of GST-Pi were moderate in normal cytotrophoblasts, mild in syncytiotrophoblasts, strong in corpus luteum, moderate to strong in salpingeal mucosa and in proliferative glands, moderate in secretory glands of indometrium and moderate in superficial squamous epithelium of cervix 2. Staining reaction of GST-L were mild in cytotrophoblasts and in syncytiotrophoblasts, of chorionic villi in corpus luteum, negative in salpingeal mucosa, very weak in proliferative glands, mild in secretory, glands of endometrium and in superficial squamous epithelium of cervix. 3. Staining reaction of GST-L were mild in cytotrophoblast and syncytiotrophoblast of choriocarcinoma, moderate in cytotrophoblasts, mild in syncytiotrophoblasts of hydatidiform mole, negative in mucinous epithelium of cust adenoma, in hyperplastia and adenocarcinoma, and mild in adenocarcinoma of cervix. 4. Staining reaction of GST-L were very weak in cytotrophoblasts and syncytiotrophoblasts of choriocarcinoma and in hydatidiform mole, negative in mucinous epithelium of cust adenoma, very weak in serous eptiethlium, negative to mild in hyperplastic and adenocarcinoma, mild in squamous cell carcinoma and adenocarcinoma of cervix. Therefore, staining reaction and distribution of GST-Pi and L isoengumes were different in normal and neoplastic cell of trophoblasts, salpinx, endometrin and cervix

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        독시사이클린 나노입자가 함유된 치주용 키토산 스트럽의 제조 및 특성

        송경숙,양재헌,김영일,정규호 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.4

        Local drug delivery by using biocompatible polymers has been developed in the treatment of periodontitis for many years. In the field of dental therapy, doxycycline is usually a first choice because of its broad-spectrum antibiotic activity. The strip releases antibiotics for a week, and the polymer should be degradable after a week. In this study, we prepared and evaluated the chitosan strips and nanoparticle strips containing doxycycline hydrochloride, and studied their antiacterial activity, dissoultion, and degrability in vitro. The weight of cast strip containing a 5 mg of doxycycline hydrochloride and a 45 mg of chitosan polymer was 57.67±0.17 mg. The release rate of doxycycline hydrochloride from the strip was measured by HPLC. The drug released from chitosan strip and nanoparticle strip was shown to be 50 ㎍/ml, in first 24 hours. In antibacterial test showed growth inhibitory activity after 24 hrs anaerobic incubation. In vitro degradability showed demolished weight of 93.74±0.08% chitosan strip, 82.48±1.29% chitosan nanoparticle strip, 2.47±1.99% polycarprolactione strip (control). These results showed that, with this doxycycline hydrochloride strip, it is feasible to obtain a sustained release of the drug within the periodontal pocket for seven days which may be improve for local drug delivery system for treatment of periodontal disease.

      • KCI등재

        Helicobacter pylori의 생육에 영향을 미치는 성분과 식품첨가물에 관한 연구

        송재철,정혜진,박현정,조은경,신완철 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.5

        본 연구에서는 일반적으로 섭취하고 있는 식품재료나 음식 중에 공통적으로 함유한 성분 또는 가공중에 많이 첨가되는 성분을 선정하여 이들이 Helicobacter pylori 생육에 어떤 영향을 미치는지를 검토하였다. 첫째, 일반식품의 주요 성분인 탄소원, 질소원, 무기질을 대상으로 Helicobacter pylori 생육에 미치는 영향을 검토하였다. 그 결과 식품성분 중 탄소원의 종류에 따라 균일 생육활성은 다르게 나타났다. 우선 단당류가 이당류나 다당류에 비교하여 생육을 촉진하였고 특히 단당류 중 포도당은 가장 균의 생육에 큰 영향을 미치는 것으로 나타났다. 그러나 만노오스는 균의 생육을 오히려 억제시키는 것으로 나타났다. 당알코올류인 솔비톨, 만니톨, 말티톨, 크리시톨 등은 균의 생육에 아무런 영향을 미치지 않은 것으로 나타났다. 질소원과 Helicobacter pylori의 생육과의 관계는 평소 식생활에서 많이 섭취된다고 생각되는 일반 음식에 많이 함유되어 있는 유기형 아미노산 성분고 무기형 질소화합물을 대상으로 균의 생육 정도를 비교하였다. 리신, 메티오닌, 시스테인, 트립토판 등은 균의 생육을 촉진하고 아르기닌, 황산암모늄, 염화암모늄 등은 균의 생육에 도움이 되지 않고 암노니아, 요소등은 균의 생육에 도움이 되지 않고 암모니아, 요소 등은 균의 생육에 조금 영향을 미침을 관찰할 수 있었다. 특히 리신과 메티오닌은 가장 균의 생육에 영향을 미치는 것으로 나타났다. 무기염류의 영향에서는 황산마그네슘, KH-2PO_4, 염화마그네슘 등은 큰 영향을 미치지 못하였고 황산철, 염화제일철, 염화제이철은 생육을 억제하는 것으로 나타났다. 식품첨가물의 Helicobacter pylori의 생육 정도를 검토한 것으로, 그 다음이 질화나트륨, 염화나트륨 순이었으며 토코페롤은 전혀 생육에 영향을 미치지 못하였다. The purpose of this study was to choose principal food components contained in diet foods and food additives used for manufacturing processed foods, and elucidate their in vivo effects on the growth pattern of Helicobacter pylori. To do this, the antibacterial effects of various sources of carbon, nitrogen and mineral as an effect agent on Helicobacter pylori were first assessed based upon bacterial growth degree. Results show that the source of carbon tested had different effects on bacterial growth of Helicobacter pylori. It was revealed that a promotional effect of monosaccharides resulted in enhanced growth of Helicobacter pylori compared with disaccharides and polysaccharides. In particular, glucose was observed to be most effective in growth of Helicobacter pylori among monosaccharides tested, whereas mannose to hinder the growth of Helicobacter pylori. Polyols such as sorbitol, mannitol, maltitol and xylitol was, however, observed to show no promotion or suppression effect on growth of Helicobacter pylori. Apart from these, the sources of amino acid and inorganic nitrogen were chosen and tested to assess the promotion or suppression effect of nitrogen sources on growth of Helicobacter pylori. It was found that amino acid such as lysine showed its promotion effect on the growth of Helicobacter pylori, while arginine, (NH_1)_2SO_4 and NH_4Cl showed no effect on its growth. Ammonia and urea were, however, observed to have a positive effect on the growth of Helicobacter pylori. Among these effect agents, lysine and methionine were revealed to show the most positive effect on growth of Helicobacter pylori. Minerals such as MgSO_4, KH_2PO_4, and MgCl_2 appeared to exert their positive growth effects, whereas CaCl_2, and CaSO_4 had a little effect. In addition FeSO_4, FeCl_2, and FeCl_3 brought suppression on the growth of Helicobacter Pylori. In studies of the growth of Helicobacter pylori by food additives, ascorbic acid showed extreme suppression on its growth. Sodium nitrate and sodium chloride were also found to be of negative effect on the growth of Helicobacter pylori in order of degree, whereas tocopherol had nothing to do with microbial growth.

      • SCOPUSSCIEKCI등재

        성장기 반대교합자의 FR Ⅲ 효과에 관한 임상적 고찰

        송경,성재현 대한치과교정학회 1989 대한치과교정학회지 Vol.19 No.2

        The purpose of this study was to assess the early effect of FR III on the growing patients with anterior cross-bite. The lateral cephalograms and models were obtained from 7 patients at the time of pretreatment and correction of anterior cross-bite. The results were as follows: 1. A slight tendency of rotation toward anterosuperior direction and the growth to anterior direction were shown in maxilla. 2. There were a little change of mandibular vertical position and increase in lower facial height although some variations existed. 3. The bodily or labial tipping movement was shown in maxillary incisors. 4. The lingual tipping of mandibular incisicors was shown in all cases. 5. Maxillary arch width increased while mandibular arch width usually changed a little although some variations existed. But it was difficult to summary in word because variable responses were noted according to a wide variety of skeletal type, growth, and malocclusion.

      • 우리나라 一部獻血者의 實態調査

        송재옹,문희주,김경희 대한임상병리사협회 1980 대한임상병리사회지 Vol.12 No.1

        As a result of inspecting the distribution chart on ABO blood group and Rho negative blood type by sex, age, occupation and month based on 77,871 blood donors with a view in understanding the real status on blood donors in our country. Data can be summerized as follows; 1. It showed that males(65.47%) who took part in the blood donation campaign were more than that of females. 2. Donors of 16 to 20 years old are 57.1%, 21 to 25 are 30.49%, 26∼30 are 8.64%, 31∼35 are 3.07% and over 36 years of age were 0.79%. It showed that majority of participants are the youth whose ages are ranging from 16 up to 20 years of ages. 3. Donor distribution by occupation showed that students were 54.01%, employers were 14.67%, businessmen were 8.58%, unemployed were 12.44% and the others were 10.3%. 4. It showed group A were 33.10%, group B were 27.81%, group 0 were 28.15% and group AB were 10.94%. It was discovered that 0.21% or 154 persons were identified Rho negative type among 77,871 donors.

      • KCI등재

        초음파 조사에 의한 트리암시놀론 아세토니드 겔의 피부투과

        송경숙,김영일,양재헌 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.2

        This study is to enhance drug penetration via skin and investigate anti-inflammation effect following adoption of ultrasound. For this goal gel containing triamcinolone was prepared and the skin penetration rate and the change effects of blood plasma ingredients and serum enzyme were investigated. Using Franz type diffusion cell and the skin of hairless mouse, the permeation enhancing effect of ultrasound was tested. After the injury by direct trauma, the blood test was performed by measuring WBC, lymphocyte, and neutrophyl, and by analyzing CPK and LDH. The ultrasound transducer whose technical specification is geometric area(GA) 1.4㎠, effective radiation area(ERA) 0.8㎠, and beam non-uniformity ratio(BNR) 6.0 max was used. The influence of frequency having an effect on skin permeation rate was higher in the case of using 1MHz and continuous treatment. The temperature of receptor phase was not influenced in skin permeation by phonophoresis. Skin permeation increase attended by intensity of ultrasound, the permeation of triamcinolone was accelerated at 2.5 w/㎠ than 1.0 w/㎠. Following muscle injury phonophoretic group the number of WBC, neutrophil and lympholyte were decreased significantly as compared with both control group and ultrasound group. The result of variation of serum CPK and LDH activity conformed to the phonophoretic effect as same pattern with the variation of WBC, neutrophil and lymphocyte.

      • 측모 두부방사선 규격사진의 기준점 선정의 다양성

        송경,성재현 慶北大學校 齒科大學 1990 慶北齒大論文集 Vol.7 No.1

        The purpose of this study was to compare the variability in locating landmarks on lateral cephalograms. Ten lateral cephalograms at CRO and maximum opening were randomly selected from adult patients. The 29 landmarks were located on CRO cephalograms by 10 tracers twicely at 1 month interval. The scattergrams consisted of two hundred points for each landmarks were obtained and analysed by computed 75% & 95% density ellipses using bivariate normal distribution. The results were as follows ; · The landmarks having relatively smaller locating errors were S, Na, Ar, Gn, Go, UIE, LIE. · The landmarks having relatively larger locating errors were Ba, Po, Co, PT, R1, R3. · The landmarks having nearly circular distributions were S, UIE, LIE, Ba, Po, R3 and those having long elliptical distributions were B, Pog, Pm, R2, Me, R4, in which B, Pog, Pm and R2 distributed vertically and Me and R4 distributed horizontally. · Each landmark had its own characteristic elliptical envelope of error and large differences in magnitude and configuration of envelope of error were found among the difference landmarks. J. Kyungpook Univ. Sch. Dent. Vol. 7, No. 1,98∼98, 1990

      • 우리나라의 農作業 災害實態에 관한 考察

        송경환,양재성 順天大學校 1997 論文集 人文社會科學篇 Vol.16 No.-

        ABSTRACT The main focus this study is the countermeasure of after agricultural work disaster. In this study, The countermeasure of after agricultural work disaster is to present the extension of industrial disaster insurance Many factory works accept the benefit of social insurance, industrial insurance, medical care insurace, national pension, employment insurance etc. But Agricultural business works accept only medical care insurance and national pension, in spite of lower income then their. Actually, Agricultural work disaster is to happen work course considerably. In order to solve such problem, the govenment must extend social insurance to agricultural work disaster.

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