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      • 김정은 시대 북한정치의 특징과 전망

        김일기(Kim, Il-Gi),이수석(Lee, Su-Suk) 북한학회 2013 북한학보 Vol.38 No.2

        이 글은 김정은 시대 북한 정치의 특징을 분석하고 향후 변화를 전망하고 있다. 북한 정치의 특정은 권력구조와 리더십 그리고 통치이념을 중심으로 분석하였다. 먼저, 북한의 권력구조는 수령체제라는 북한 정치체제의 특성에 주목하여 유일영도체계와 함께 권력엘리트의 재편에 초점을 두었다. 김정은 시대 유일영도체계는 김정일 시기에 비해 약해지고 있으며, 권력엘리트들은 당-정-군 모두에서 세대교체가 가속화되고 있다. 둘째, 김정은의 정치적 리더십은 인격적 리더십과 제도적 리더십을 통해 분석하였다. 김정은은 김정일 사망 직후 최고지도자의 지위에 기반한 제도적 리더십을 갖춘 이후, 현재까지 인격적 리더십 확립에 매진하고 있다. 셋째, 북한의 통치이념은 주체사상에서 김일성-김정일주의로 변경되었다. 그리고 북한은 김정은 시대의 실천담론으로서 김정일 애국주의를 확산시키고 있다. 결론적으로, 북한은 김정은 시대의 새로운 비전과 목표를 제시할 것이며, 이를 통해 김정일과의 차별성 및 변화를 모색할 가능성이 높다. This paper analyzes the characteristics of North Korean politics and predicts future changes under Kim Jong-Un era. It is analyzed power structure, political leadership and ruling ideology as the characteristics of North Korean politics. First, The power structure is consist of 'uilyongdochege (monolithic leadership)' and change of power elite. The 'uilyongdochege' has weakened and the replacement of power elite has accelerated compared to Kim Jong-Il era. Second, there were analyzed personal leadership and positional leadership as Kim Jong-un's political leadership. Kim Jong-Un established institutional leadership based on position of supreme leader soon after the death of Kim Jong-Il and has been trying to establish personal leadership. Third, The ruling ideology of North Korea changed from 'Juche Ideology' to 'Kimilsung-Kimjongilism'. And The 'KimJongil Patriotism' is spreading to the entire society as the discourse for practice 'Kimilsung-Kimjongilism'. Finally, North Korea will present a new vision and goals and try to differentiate Kim Jong-Un era from Kim Jong-Il era.

      • KCI등재

        한국인 전반적 급진성 치주염 환자에서 IL-6 유전자 다변성에 관한 연구

        방선정,김일,옥수,영준,정현주,Bang, Sun-Jung,Kim, Il-Shin,Kim, Ok-Su,Kim, Young-Jun,Chung, Hyun-Ju 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.4

        Purpose: The purpose of this study was to investigate the association of generalized aggressive periodontitis with IL-6 promoter gene single nucleotide polymorphisms(SNP). Material and Methods: The study population consisted of 52 generalized aggressive periodontitis patients(GAP) and 30 periodontally healthy control subjects, who were systemically healthy non-smokers. Genomic DNA was obtained from buccal swab. The IL-6 promotor SNP at the positions of -597, -572, and -174 were genotyped by amplifying the polymorphic region using polymerase chain reaction(PCR), restriction enzyme digestion and gel electrophoresis. Result: The genotype distributions for G/G, G/A and A/A genotypes of IL-6 -597 were 30.8%, 40.4%, and 28.8% in the GAP group and 53.3%, 40%, and 6.7% in the control group and were statistically different between 2 groups(p<0.05). Allele 2 frequency of IL-6 -597 were significantly higher in the GAP group than the control group(p<0.01). At the position of IL-6 -572, the distribution for C/C, C/G and G/G genotypes were 23.1%, 55.8% and 21.2% in the GAP group and 20%, 33.3%, and 46.7% in the control group. In female subjects, the genotype distribution were significantly different between 2 groups(p<0.01). In male subjects, allele 2 frequency of IL-6-572 was significantly lower in the GAP group than the control group(p<0.05). The genotype distribution of IL-6 -174 in the GAP group were 96.2%, 3.8% for G/G, G/C genotypes whereas only the G/G genotype was detected in the control group. Conclusion: In conclusion, significant associations were found in IL-6 gene promoter(-597, -572) polymorphisms and generalized aggressive periodontitis. Further cohort study will be necessary in larger population.

      • KCI등재

        일반논문 : 김정은 체제의 대남정책과 남북관계

        김일기 ( Il Gi Kim ) 한국외국어대학교 글로벌정치연구소 2012 글로벌정치연구 Vol.5 No.1

        북한은 작년 김정일 사망 이후 권력승계의 속도를 빠르게 진행하여 올해 4월의 제4차 당대표자회와 제12기 제5차 최고인민회의를 통해 김정은 체제를 공식적으로 출범시켰다. 현재 김정은 체제의 대내외 정책 방향은 김정일의 유훈에 따라 진행되고 있으나, 구체적 내용들은 아직 공개되지 않고 있다. 이 연구는 이러한 점에 주목하여 김정은 체제의 대남정책 방향과 남북관계를 전망하였다. 김정은 체제는 북한의 전통적 대남전략 목표인 ``한반도 공산화``를 계승함과 동시에 강온 양면의 이중적 대남정책을 전개할 것이다. 북한의 대남 유화정책은 경제난 해결과 미북 관계 개선 및 6자회담 재개를 위해 전개될 가능성이 높다. 반면, 대남 강경정책은 미북 관계와 북핵 협상 미진, 체제위기 탈피, 남북관계 주도권 확보 차원에서 추진될 가능성이 높다. 김정은 시대의 남북관계는 북한의 이중적 대남정책에 따라 경색과 회복의 국면을 반복할 것이다. 북한의 대남정책에서 새로운 변화가 없는 한 당분간 남북관계는 경색국면을 벗어나기 어렵다. 그러나 장기적 측면에서 보면 남북관계는 김정은 체제의 안정화 속에서 제한적이지만 점진적으로 개선되는 방향으로 나아갈 가능성이 높다. 아마도 남북관계와 한국, 미국, 중국의 권력교체가 완료되고 새로운 정부가 출범하는 2013년 이후에 새로운 변화의 가능성을 기대할 것으로 예상된다. Kim Jong-un regime has been officially launched from the fourth Conference of the Workers` Party of North Korea, and the fifth session of the 12th Supreme People`s Assembly was held on April 2012. The policy of Kim Jong-un regime has been followed by the teachings left by Kim Jong-il, but the details of it have not been known. So, this article analyzes not only the North Korea`s Policy against South Korea, but also inter-Korea relations which could be expected in the Kim Jong-un Regime. While it maintains the past policy objective, "the communization of the entire Korean peninsula", North Korea will be continued to purse the dual strategy of hardline and moderate toward South Korea. Inter-Korea relations of Kim Jong-un Era will be swung back and forth such as pendulum in the wall clock. If there is no change in strict policy toward South Korea, inter-Korea relations will become progressively worse. Taking the long-term perspective, however, inter-Korea relations will be improved gradually.

      • SCIESCOPUSKCI등재

        괴화 추출물이 대식세포에서의 nitric oxide와 interleukin-6의 생성에 미치는 영향

        이지은,이주연,최점일,종관,성조,Lee, Ji-Eun,Lee, Ju-Youn,Choi, Jeom-Il,Kim, Chong-Kwan,Kim, Sung-Jo 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.1

        Both nitric oxide (NO) and interleukin-6 (IL-6) have been thought to have a role in the pathogenesis of inflammatory periodontal disease as it does in other inflammatory diseases, and the inhibitors of NO and IL-6 production have been considered as potential anti-inflammatory agents. In this study, we evaluated methanol extract of Sophorae Flos for inhibition of NO and IL-6 production in Prevotella intermedia LPS-induced mouse macrophages RAW264.7 cells. Dried Sopharae Flos was sliced, and extracted with 100% methanol. LPS from p. intermedia ATCC 25611 was prepared by the standard hot phenol-water method. NO production was assayed by measuring the accumulation of nitrite in culture supematants and IL-6 was measured using mouse IL-6 ELISA kit. Western blot analysis of iNOS and analysis of reverse transcription (RT)-PCR products were carried out. The methanol extract of Sophorae Flos concentration-dependently reduced the production of NO and the expression of iNOS protein and mRNA in RAw264.7 cells treated with P. intermedia LPS. Sophorae Flos also suppressed IL-6 production and the expression of IL-6 mRNA in RAw264.7 cells stimulated by P. intermedia LPS. The inhibition of NO and IL-6 production by Sophorae Flos may be useful in the therapy of inflammatory diseases such as periodontitis. This hypothesis, however, remains to be tested.

      • SCOPUSKCI등재

        주조직적합항원이 불일치하는 마우스 동종 조혈모세포이식에서 IL-2로 유도된 CD4+CD25+ T세포를 이용한 이식편대숙주병의 억제

        현재호,정대철,정낙균,박수정,민우성,태규,최병옥,원일,한치화,학기,Hyun, Jae Ho,Jeong, Dae Chul,Chung, Nak Gyun,Park, Soo Jeong,Min, Woo Sung,Kim, Tai Gyu,Choi, Byung Ock,Kim, Won Il,Han, Chi Wha,Kim, Hack Ki 대한면역학회 2003 Immune Network Vol.3 No.4

        Background: In kidney transplantation, donor specific transfusion may induce tolerance as a result of some immune regulatory cells against the graft. In organ transplantation, the immune state arises from a relationship between the immunocompromised graft and the immunocompetent host. However, a reverse immunological situation exists between the graft and the host in hematopoietic stem cell transplantation (HSCT). In addition, early IL-2 injections after an allogeneic murine HSCT have been shown to prevent lethal graft versus host disease (GVHD) due to CD4+ cells. We investigated the induction of the regulatory CD4+CD25+ cells after a transfusion of irradiated recipient cells with IL-2 into a donor. Methods: The splenocytes (SP) were obtained from 6 week-old BALB/c mice ($H-2^d$) and irradiated as a single cell suspension. The donor mice (C3H/He, $H-2^k$) received $5{\times}10^6$ irradiated SP, and 5,000 IU IL-2 injected intraperitoneally on the day prior to HSCT. The CD4+CD25+ cell populations in SP treated C3H/He were analyzed. In order to determine the in vivo effect of CD4+CD25+ cells, the lethally irradiated BALB/c were transplanted with $1{\times}10^7$ donor BM and $5{\times}10^6$ CD4+CD25+ cells. The other recipient mice received either $1{\times}10^7$ donor BM with $5{\times}10^6$ CD4+ CD25- cells or the untreated SP. The survival and GVHD was assessed daily by a clinical scoring system. Results: In the MLR assay, BALB/c SP was used as a stimulator with C3H/He SP, as a responder, with or without treatment. The inhibition of proliferation was $30.0{\pm}13%$ compared to the control. In addition, the MLR with either the CD4+CD25+ or CD4+CD25- cells, which were isolated by MidiMacs, from the C3H/He SP treated with the recipient SP and IL-2 was evaluated. The donor SP treated with the recipient cells and IL-2 contained more CD4+CD25+ cells ($5.4{\pm}1.5%$) than the untreated mice SP ($1.4{\pm}0.3%$)(P<0.01). There was a profound inhibition in the CD4+CD25+ cells ($61.1{\pm}6.1%$), but a marked proliferation in the CD4+CD25- cells ($129.8{\pm}65.2%$). Mice in the CD4+CD25+ group showed low GVHD scores and a slow progression from the post-HSCT day 4 to day 9, but those in the control and CD4+CD25- groups had a high score and rapid progression (P<0.001). The probability of survival was 83.3% in the CD4+CD25+ group until post-HSC day 35 and all mice in the control and CD4+CD25- groups died on post-HSCT day 8 or 9 (P=0.0105). Conclusion: Donor graft engineering with irradiated recipient SP and IL-2 (recipient specific transfusion) can induce abundant regulatory CD4+CD25+ cells to prevent GVHD.

      • KCI등재
      • KCI등재SCOPUS
      • KCI등재

        관절경하 AO 무두 압박 나사를 이용한 견갑골 전방 관절와 분쇄 골절의 치료

        형식(Hyung-Sik Kim),고일현(Il-Hyun Koh),성국(Sung-Guk Kim),천용민(Yong-Min Chun),성재(Sung-Jae Kim),강호정(Ho-Jung Kang) 대한견주관절의학회 2011 대한견주관절학회지 Vol.14 No.1

        목적: 견갑골 전방 관절와 분쇄 골절에 대해 관절경하 정복 및 AO 무두 압박 나사를 이용하여 골편을 고정한 증례를 보고하고자 한다. 대상 및 방법: 31세 남자로 내원 2주 전 추락 후 발생한 좌측 견관절의 전방 관절와 분쇄 골절에 대하여 관절경하에서 골절을 정복한 후, 표준 전상방 삽입구를 통해 1.1 mm K 강선을 가이드핀으로 삽입하고 AO 무두 압박 나사로 골편을 고정하였다. 결과: 수술 후 12개월째 견관절의 운동 범위는 정상 범위로 회복 되었으며, 골절은 유합을 얻었고 일상 생활에 불편감은 없었다. 결론: AO 무두 압박 나사는 나사의 길이가 다양하여 작은 관절와 골편에 사용하기 적합하고, 가이드 핀의 길이가 상대적으로 짧으나 1.1 mm K 강선으로 대체가 가능하며, 나사 돌리개 (screw driver)나 천공기 (drill bit) 등의 동반 기구의 길이가 길어 비교적 깊은 위치의 견갑과 골절의 고정에 사용하기 편리하여 관절경적 고정술 시 유용하게 이용할 수 있을 것으로 생각된다. Purpose: We present a case of anterior glenoid rim comminuted fracture that was treated with arthroscopic reduction and an AO headless compression screw (HCS) fixation. Materials and Methods: A 31-year old man complained of left shoulder pain after falling down on stairs. The anterior glenoid comminuted fragments were arthroscopically reduced. Fixation with an AO HCS was done after placement of 1.1 mm Kirschner wire as a guide pin through a standard cannulated anterosuperior portal. Results: Twelve months after the operation, union of the fracture was achieved and the range of motion was fully recovered. He did not complain of any discomfort during his activities of daily living. Conclusion: An AO HCS had various screw sizes and this was good for fixation of a small glenoid fracture and a long drill bit and screw driver were useful for fixation of deep seated glenoid fracture. A short guide wire could be replaced by a 1.1 mm K-wire. An AO HCS was useful for fixation of an anterior glenoid rim comminuted fracture.

      • KCI등재

        WE START 교육을 위한 다중지능 이론 기반의 협력학습 모형 개발 연구

        지일(Kim Jee Il) 교육종합연구원 2007 교육종합연구 Vol.5 No.1

        이 연구는 철원지역 위스타트 교육프로그램 개발에 효과적으로 활용할 수 있는 협력학습 설계 모형을 개발하는데 목적이 있다. 이를 위해 철원지역 교육 수요자에 대한 기초조사 결과를 토대로 학습자 및 환경 특성을 파악하고, 이 결과를 모형 설계의 초기 근거로 하였다. 이렇게 구안된 초기모형은 Rubinstein의 모형 설계 과정을 통해 지속적으로 수정 보완되었고, 전문가의 검토를 거쳐 최종적인 협력학습 설계모형으로 도출되었다. 마지막으로 모형의 타당성을 검증하기 위해 형성적 사례연구의 과정에 따라 그 효과를 살펴보았다. 이처럼 완성된 모형은 “(1) 다중지능 분석, (2) 과제 개발, (3) 연계, 확장 활동의 설계, (4) 평가 및 성찰”의 4가지 주요 단계로 구성된다. 이 모형의 적용 결과, 교육적 효과성, 효율성, 매력성 측면에서 유용한 것으로 나타났으나, 결론을 통해 실제 적용에 필요한 주의사항과 개선점을 지적하였다. The purpose of this study is to propose an collaborative learning model for elementary school children with low income parent in Chol-won and examine the practical usability of the model in WE START education program. The model was developed based on the following stages. At the beginning stage, questionnaires were used for 18 elementary school children and 12 parents in low income family to collect data to establish basic principles which facilitates the practical usability of the model. This study reviewed existing multiple intelligences theories, collaborative learning theories and then integrated the principles of those theories using formative case study to draw the model. Through the extensive literature reviews and survey study, basic frame of the model was developed. This paper suggests four essential stages of the model such as (1) analyzing multiple intelligences, (2) establishing task, (3) designing the activities of matching and stretching, (4) evaluation and reflection. The study evaluated the model using quantitative research method to test the validity and the usability in terms of its effectiveness, efficiency, and attractiveness and also reveals some limitations. The limitations and related suggestions were discussed.

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