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차영주,류왕성,김용성,서양관,현창훈,권기익,유언호 대한내과학회 1988 대한내과학회지 Vol.35 No.3
A study of a family with a hereditary deficiency of antithrombin III (AT III), as measured by an immunoassay, is reported. The propositus was a 37-year-old male with a 3-year history of recurrent attacks of deep vein thrombosis of the lower legs. A study of his family revealed a disposition to thromboembolism on the parental side and an autosomal dominant pattern of inheritance, involving five of ten siblings. They have suffered from frequent episodes of venous thrombosis of the lower legs.
Cha, Choong-Hwan,Park, Chan-Jeoung,Cha, Young Joo,Kim, Hyun Kyung,Kim, Duck Hee,Bae, Jae Hoon,Jung, Jae-Seol,Jang, Seongsoo,Chi, Hyun-Sook,Lee, Dong Soon,Cho, Han-Ik Williams Wilkins Co 2009 American journal of clinical pathology Vol.131 No.2
<P>We compared the TEST 1 (Alifax, Padova, Italy) and Westergren methods of measuring the erythrocyte sedimentation rate (ESR) to assess inflammation. The ESR was measured by both methods in 154 blood samples from patients with malignancy (n = 69), autoimmune disease (n = 44), or infection (n = 41). Total protein, albumin, and C-reactive protein (CRP) levels were measured in each plasma sample, and albumin and alpha(1)-, alpha(2)-, beta(1)-, beta(2)-, and gamma-globulin fractions were measured by capillary electrophoresis. TEST 1 ESR values were significantly lower than the Westergren values, by 10.9 mm/h. We found that the correlations of TEST 1 ESR values with inflammatory protein levels (total protein, globulin, CRP, and alpha(1)-, alpha(2)-, beta(2)-, and gamma-globulin) were better than those obtained using the Westergren method. These findings indicate that ESR measurements by TEST 1 reflect inflammation better than do those by the Westergren method in patients with malignancy, autoimmune disease, or infection.</P>
Case Report : Cushing syndrome in pregnancy secondary to adrenal adenoma
( Ik Jin Chang ),( Hyun Hwa Cha ),( Jung Han Kim ),( Suk Joo Choi ),( Soo Young Oh ),( Cheong Rae Roh ) 대한산부인과학회 2013 Obstetrics & Gynecology Science Vol.56 No.6
We report a case of Cushing syndrome secondary to adrenal adenoma presenting with hypertension and oligohydramnios during pregnancy. The tumor was confirmed by magnetic resonance imaging at 28 week 3 day weeks of pregnancy and was removed surgically at 29 week 1 day weeks of gestation. After surgery, hypertension subsided and amniotic fluid volume returned to normal range. The gravid woman subsequently delivered a healthy infant at term.
Cha Dong Ik,강태욱,Min Ji Hye,Joo Ijin,Sinn Dong Hyun,하상윤,김경아,Lee Gunwoo,이종현 대한초음파의학회 2021 ULTRASONOGRAPHY Vol.40 No.4
Purpose: The aim of this study was to develop and validate a fully-automatic quantification of the hepatorenal index (HRI) calculated by a deep convolutional neural network (DCNN) comparable to the interpretations of radiologists experienced in ultrasound (US) imaging. Methods: In this retrospective analysis, DCNN-based organ segmentation with Gaussian mixture modeling for automated quantification of the HRI was developed using abdominal US images from a previous study. For validation, 294 patients who underwent abdominal US examination before living-donor liver transplantation were selected. Interobserver agreement for the measured brightness of the liver and kidney and the calculated HRI were analyzed between two board-certified radiologists and DCNN using intraclass correlation coefficients (ICCs). Results: Most patients had normal (n=95) or mild (n=198) fatty liver. The ICCs of hepatic and renal brightness measurements and the calculated HRI between the two radiologists were 0.892 (95% confidence interval [CI], 0.866 to 0.913), 0.898 (95% CI, 0.873 to 0.918), and 0.681 (95% CI, 0.615 to 0.738) for the first session and 0.920 (95% CI, 0.901 to 0.936), 0.874 (95% CI, 0.844 to 0.898), and 0.579 (95% CI, 0.497 to 0.650) for the second session, respectively; the results ranged from moderate to excellent agreement. Using the same task, the ICCs of the hepatic and renal measurements and the calculated HRI between the average values of the two radiologists and DCNN were 0.919 (95% CI, 0.899 to 0.935), 0.916 (95% CI, 0.895 to 0.932), and 0.734 (95% CI, 0.676 to 0.782), respectively, showing high to excellent agreement. Conclusion: Automated quantification of HRI using DCNN can yield HRI measurements similar to those obtained by experienced radiologists in patients with normal or mild fatty liver. Purpose: The aim of this study was to develop and validate a fully-automatic quantification of the hepatorenal index (HRI) calculated by a deep convolutional neural network (DCNN) comparable to the interpretations of radiologists experienced in ultrasound (US) imaging.Methods: In this retrospective analysis, DCNN-based organ segmentation with Gaussian mixture modeling for automated quantification of the HRI was developed using abdominal US images from a previous study. For validation, 294 patients who underwent abdominal US examination before living-donor liver transplantation were selected. Interobserver agreement for the measured brightness of the liver and kidney and the calculated HRI were analyzed between two board-certified radiologists and DCNN using intraclass correlation coefficients (ICCs).Results: Most patients had normal (n=95) or mild (n=198) fatty liver. The ICCs of hepatic and renal brightness measurements and the calculated HRI between the two radiologists were 0.892 (95% confidence interval [CI], 0.866 to 0.913), 0.898 (95% CI, 0.873 to 0.918), and 0.681 (95% CI, 0.615 to 0.738) for the first session and 0.920 (95% CI, 0.901 to 0.936), 0.874 (95% CI, 0.844 to 0.898), and 0.579 (95% CI, 0.497 to 0.650) for the second session, respectively; the results ranged from moderate to excellent agreement. Using the same task, the ICCs of the hepatic and renal measurements and the calculated HRI between the average values of the two radiologists and DCNN were 0.919 (95% CI, 0.899 to 0.935), 0.916 (95% CI, 0.895 to 0.932), and 0.734 (95% CI, 0.676 to 0.782), respectively, showing high to excellent agreement.Conclusion: Automated quantification of HRI using DCNN can yield HRI measurements similar to those obtained by experienced radiologists in patients with normal or mild fatty liver.
Dependence of optical trapping efficiency on the beam radius-to-aperture radius ratio
Hyun Ik Kim,Cha Hwan Oh,In Je Joo,Kang Bin Im 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.43 No.I
Microparticles were optically trapped and manipulated by using optical tweezers. The optical trapping efficiency on a 5 $\mu$m-sized microsphere was measured as a function of the ratio of the beam radius-to-the aperture radius ($W_0 / R$). The optical trapping efficiency increased with the ratio of the beam radius-to-the aperture radius and became constant over the region $W_0 / R > 1.5$. We analyzed this behavior of the optical trapping efficiency by using the ray optics model. From the experimental results, we confirmed that the ratio could be a factor causing wide variability of the reported experimental data concerning force or efficiency measurements. Also, these results may be helpful in reducing the optical damage in trapping of biological cells.