유소년영재의 창의적 성향·창의적사고력·다중지능·도덕성에 관한 탐색

류봉선,이경은,홍성용 韓國英才學會 2011 영재교육연구 Vol.21 No.4

Gifted children cultivate their many talents through experience. For the purpose of revealing the talents or abilities of gifted children, it is necessary to provide them with various types of environment for their exploration from the early stage of their school age. In addition, knowing their concern, aptitude and interest from the early stage of their school age will be much helpful for them to grow, advance and search for their future career path. Accordingly, the purpose of this study is to examine the definitional and cognitive characteristics of gifted children through tests on the creative disposition, creative thinking power, multiple intelligences and morality of gifted children at the early stage of their school age in order to provide basic information on the gifted children studies. Accordingly, 90 gifted children were selected as the participants of this study through observation and recommendation. The result showed much difference between the second grade and the third grade in their creative disposition, creative thinking power, multiple intelligences and morality according to school year. As for the difference according to gender, the second grade female students showed meaningful differences in the sub-domain of creative disposition, multiple intelligences and morality and the third grade showed no differences. Such study result shows that students in upper school year clearly have their own sense of purpose. 영재들은 경험을 통해 많은 재능을 발달시켜나간다. 영재들의 재능 혹은 능력을 최대한 발현시키기 위해서 학령기 초기부터 다양한 환경을 제공하고 탐색할 수 있도록 해야 한다. 또한 영재들이 가진 그들의 관심과 적성 및 흥미를 학령기 초기부터 알 수 있다면 성장하고 발달하며 진로를 탐색하는데 많은 도움이 될 것이다. 따라서 본 연구에서는 학령기 초기에 해당하는 유소년 영재의 창의적 성향·창의적사고력·다중지능·도덕성의 검사를 통해 유소년 영재의 정의적·인지적 특성을 탐색하여 유소년 영재연구의 기초자료로 제공하고자 하는데 목적이 있다. 이를 위해 관찰추천을 통해 선발된 유소년 영재 90명을 대상으로 하였다. 그 결과 창의적 성향·창의적사고력·다중지능·도덕성의 학년에 따른 결과는 2학년과 3학년의 차이가많음을 알 수 있었다. 성별에 따른 차이는 창의적 성향·다중지능·도덕성의 하위영역에서 여학생이 2학년에서 높았으며 3학년은 차이가 없는 결과를 보였다. 이러한 연구결과는 유소년 영재들은 남녀 구분 보다 발달적 이해와 영재의 특성을 고려한 질 높은 적절한 학습 환경의 초기노출이 유능한 인재로의 성장에 도움을 주며, 학년이 높을수록 앞으로 자기 목표의식을 분명히 가지고 있음을 보여주는 결과이다.

Pseudomonas sp. EL-G527에 의한 환경친화성 생물계면활성제의 생산최적조건

차미선,임은경,이근희,조순자,손흥주,이상준 한국환경과학회 2002 한국환경과학회지 Vol.11 No.3

A biosurfactant-producing microorganism was isolated from activated sludge by enrichment culture when grown on a minimal salt medium containing n-hexadecane as a sole carbon source. This microorganism was identified as Pseudomonas sp. and it was named Pseudomonas sp. EL-G527. It's optimal culture condition is 2% n-hexadecane, 0.2% NH_4NO_3, 0.3% KH_2PO_4, 0.3% K_2HPO_4, 0.02% MgSO_4·7H_2O, 0.0025% CaCl_2·6H_2O, 0.0015% FeSO_4·7H_2O in 1ℓ distilled water and initial pH 7.0. Cultivation was initiated with a 2% inoculum obtained from starter cultures grown in 30 ㎖ of the same medium in 250 ㎖ flask. They were cultivated at 30 ℃ in reciprocal shaking incubator and the highest biosurfactant production was observed after 4 days.

제2형 당뇨병 환자에서 적극적 환자 교육이 혈당조절에 미치는 효과

이윤욱,황원선,최선정,이동훈,김도현,이은희,홍은경,노혜림,정윤석,이관우,김현만 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.1

연구배경: 현재까지의 당뇨병 교육에 대한 노력은 제한되었으며, 연구 결과를 보면 식사 조절 교육과 체중 조절 프로그램을 수행한 환자들 중 적극적이고 기간이 긴 교육을 받은 경우, 성공적 결과가 나타남을 알 수 있었다. 자가관리나 체중감량 등의 당뇨병 치료의 중요한 목표는 적극적이고 긴 기간의 교육 없이는 시행되기 어렵다. 본 연구에서는 외래에서 당뇨병 환자를 대상으로 시행할 수 있는 행동 및 식사 교육 등의 적극적 교육 프로그램을 개발하여 제2형 당뇨병 환자들을 대상으로 이들에게 식사 조절 방법에 대한 목표설정과 문제에 직면하였을 때의 해결 방법 등을 교육해서 궁극적으로는 적극적 자아관리에 연결될 수 있도록 도와주는 것을 목적으로 기존의 통상적 교육과 보다 적극적인 교육이 당뇨병 환자의 혈당 조절에 어떠한 영향을 미치는지에 대해 알아보기 위해 다음과 같은 연구를 시행하였다. 방법: 본 연구는 아주대학교 병원 내분비 대사 내과를 처음으로 방문하여 치료받았던 58명의 제2형 당뇨병 환자를 대상으로 하였다. 내원 환자들을 무작위하게 추출하여 진찰권 번호 끝자리에 따라 홀수는 통상적 교육군(conventional education group, CE)과 짝수는 적극적 교육군(intensive education group, IE)으로 나누어 교육하고, 3개월후에 교육의 효과를 평가하였다. 결과: 1) 연구 대상자들의 교육 전과 후의 공복혈당, 식후2시간 혈당 및 HbA_lc 치는 IE군과 CE군 모두 각 그룹 내에서, 유의적으로 감소하였다(p<0.05). IE군에서는 공복혈당이 12.4nmol/L에서 7.7nmol/L로, 식후2시간 혈당이 20.3nmol/L에서 10.9nmol/L으로, HbA_lc치가 9.4%에서 7.0%로 모두 교육 전에 비하여, 교육 후에 감소(p<0.05)하였고, CE군도 공복혈당은 10.9nmol/L에서 9.4nmol/L로, 식후2시간 혈당은 17.1nmol/L에서 14.6nmol/L으로 HbA_lc가 8.5%에서 7.3%으로 모두 교육 후에 감소하였다(p<0.05). 또한, 교육 전에 비하여 교육 후에 공복 혈당 및 HbA_lc치가 감소하는 정도는 IE군에서의 감소가 CE군에 비해 더 현저하였다Op<0.05). 2) 식사에 대한 태도는 3부분으로 나누어 식사에 대한 규칙성, 식사 내용의 균형성, 식사에 대한 태도 등으로 나누어 각각의 점수 및 총점을 비교하였으며 교육 전에 비해 교육 후에 연구 대상자들의 식태도가 향상되었음을 알 수 있었다. 두 그룹간의 차이를 분석한 결과 식사의 균형성 항목에서와 총점에서 유의적으로 두 그룹의 차이를 보여서 IE군에 CE군에 비해 식사의 균형성 측면이 향상되었고, 전체적인 식태도가 좋아졌음을 알 수 있었다(p<0.05). 결론: 비교적 긴 기간은 아니지만 적극적 교육을 받은 당뇨병 환자들이 통상적 교육을 받은 군보다 혈당 및 HbA_lc, 식태도 점수등의 수치의 호전뿐만 아니라 당뇨병 환자의 삶에서 중요한 부분을 차지하는 식사요법 관리 부분에 있어 향상됨을 알 수 있었다. Background: To this date, efforts to develop effective methods for the education of diabetic patients have been limited. The important goal of self-management and weight control for diabetic treatment can not be attained without long and intensive period of education. This study was undertaken to assess the effectiveness of an intensive educational program, of behavior and diet control, which was carried out on subjects with type 2 diabetes, on and out-patient basis. we compared the effectiveness of an intensive education programme with that of a conventional education programme for the self-management of type 2 diabetic patients. Methods: Subjects with type 2 diabetes were randomly selected, and allocated to one of two groups. One group received a conventional education programme of self-management(the CE group), and the second group received an intensive education progammes for three months, after which the effectiveness of the programmes were evaluate. Results: 1) The levels of fasting blood sugar(FBS), postprandial 2 hour blood sugar(PP2h) and HbA1c were significantly lowered in both groups following the intervention(p<0.05). In the IE group, the FBS declined from 12.4nmol/L to 7.7nmol/L, PP2h declined from 20.3nmol/L to 10.9nmol/L, and the HbA_lc showed a similar decline from 9.4 to 7.0% after intervention(p<0.05). In the Ce group, the FBS declined from 10.9 to 9.4nmol/l, the PP2h decreased from 17.1 to 14.6nmol/l, and the HbA_lc also decreased from 8.5 to 7.3% after intervention(p<0.05). The decrease in the FBS and HbA_lc following the educational intervention was more pronounced in the IE group than the CE group(p<0.05). 2) The effectiveness of the education programmes in promoting appropriate dietary behavior in the diabetic subjects was assessed by a scoring system in three parts: a regularity score, a balance score and an attitude score. From a comparative study of the three scores, the patients attitudes were observed to be much improved in both the groups following the intervention compared to before the programmes, but the balance and total scores were significantly higher in the IE group than the CE group(p<0.05). Conclusion: We can conclude that the intensive diabetic education programme is more effective than a conventional programme, not only in improving the patients' levels of glucose, HbA_lc, and dietary score, but also the diabetic patients self-control abilities, promoting behavioral change, and prompting problem solving capabilities in respect to the everyday problems that they have to face throughout their lives(J Kor Soc Endocrinol 18:63∼72, 2003).

의학논평 : 한국인 성인 당뇨병환자에서 항 GAD 항체 양성률

홍은경 ( Eun Gyoung Hong ) 대한당뇨병학회 2009 Diabetes and Metabolism Journal Vol.33 No.1

CARE 지침에 따른 모자보건과 기능영양학회지의 증례보고에 대한 질 평가연구

박경은(Gyoung Eun Park),문정현(Jeong Hyun Moon),홍수화(Soo Hwa Hong),김은정(Eun Jung Kim),성원석(Won Suk Sung) 대한모유수유한의학회 2023 nipple confusion,breastfeeding consultation,IBCLC, Vol.4 No.1

Objectives: This study was performed to evaluate the quality of case reports from the Maternal and Child Health Care & Functional Medicine and Nutrition Association in accordance with CARE (CAse REport) guidelines. Methods: Researchers selected case reports of Maternal and Child Health Care & Functional Medicine and Nutrition Association in the database of Google Scholar. The quality of selected reports was assessed based on CARE guidelines. Results: Total of 12 case reports were included in this study. Reporting rate of each sub-items was 92.59% at the maximum, 62.96% at the minimum, 77.42% at the median. ‘7 Time line’, ‘8b Diagnostic challenges’, ‘10c Intervention adherence and tolerability’, ‘10d Adverse and unanticipated events’, ‘12 Patient perspective or experience’, ‘13 Informed consent’ were missed in more than 50% of the reports. Conclusion: For improvement of the quality of case reports, it is necessary to evaluate case reports from the Maternal and Child Health Care & Functional Medicine and Nutrition Association in adherence to CARE guidelines.

Genetic Variants in Key Regulators of Necroptosis Predict Prognosis of Non-small Cell Lung Cancer after Surgical Resection

( Ji Eun Park ),( Shin Yup Lee ),( Jang Hyuck Lee ),( Mi Jeong Hong ),( Jin Eun Choi ),( Hyo-gyoung Kang ),( Sook Kyung Do ),( Sunwoong Lee ),( Ji Yun Jeong ),( Kyung Min Shin ),( Young Woo Do ),( Eun 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0

노인 당뇨병 환자의 약물 치료

홍은경 ( Eun Gyoung Hong ) 대한내과학회 2011 대한내과학회지 Vol.80 No.6

The worldwide prevalence of type 2 diabetes increases with age and almost 40% of men and more than 50% of women in Korean diabetic patients are over the age of 65. Recent clinical trials suggest that early intensive glycemic control reduces chronic complications associated with morbidity and mortality in type 2 diabetic patients. The principles of management of type 2 diabetes in the elderly are not different from those in middle-aged patients. However, before initiating any form of glucose-lowering therapy in the elderly it is necessary to assess the patient overall health status, coexisting illnesses, social environment, psychological well-being and degree of cognitive function. Furthermore, it should be considered to keep glucose control on individualized target without the risk of hypoglycemia in elderly diabetic patients due to the more deleterious and serious conditions. The old and more recent oral glucose-lowering agents and insulins are effective in the elderly patient. The characteristics and side effects of diabetic agents should be carefully reviewed by clinician before starting any form of medication in the elderly. (Korean J Med2011;80:635-642)

일개 대학병원에서의 당뇨병 관리 현황 (Korean Diabetes J 33(3):241-250, 2009) (pp.353-354)

홍은경 ( Eun Gyoung Hong ) 대한당뇨병학회 2009 Diabetes and Metabolism Journal Vol.33 No.4

Intronic variant of EGFR is associated with GBAS expression and survival outcome of early‐stage non‐small cell lung cancer

Hong, Mi Jeong,Lee, Shin Yup,Choi, Jin Eun,Kang, Hyo‐,Gyoung,Do, Sook Kyung,Lee, Jang Hyuck,Yoo, Seung Soo,Lee, Eung Bae,Seok, Yangki,Cho, Sukki,Jheon, Sanghoon,Lee, Jaehee,Cha, Seung Ick,Kim, C Wiley-Blackwells 2018 Thoracic cancer Vol.9 No.8

<P><B>Background</B></P><P>Genome‐wide association studies have indicated that most of the currently identified disease and trait‐associated single nucleotide polymorphisms (SNPs) are intronic or intergenic. RegulomeDB is a recently developed database that provides functional annotations for regulatory features of SNPs located in non‐coding regions. We evaluated the potential regulatory SNPs in the <I>EGFR</I> gene region using RegulomeDB and their associations with prognosis after surgery in non‐small cell lung cancer (NSCLC) patients.</P><P><B>Methods</B></P><P>A total of 698 patients with surgically resected NSCLC were enrolled and seven SNPs were selected based on the RegulomeDB database. All SNPs were genotyped using SEQUENOM MassARRAY iPLEX assay.</P><P><B>Results</B></P><P>Among the seven SNPs evaluated, rs9642391 (<I>EGFR</I> ivs19+2851C>G) was significantly associated with survival outcome (adjusted hazard ratio [HR] for overall survival = 0.70, 95% confidence interval [CI] 0.56–0.87, <I>P</I> = 0.001; adjusted HR for disease‐free survival = 0.82, 95% CI 0.70–0.97, <I>P</I> = 0.02; under a codominant model). According to RegulomeDB, rs9642391C>G, which is located in intron 19 of <I>EGFR</I>, was predicted to influence the expression of <I>GBAS</I> but not <I>EGFR</I>. As predicted, rs9642391C>G was associated with <I>GBAS</I> (<I>P</I> = 0.024) but not <I>EGFR</I> messenger RNA expression in tumor tissues.</P><P><B>Conclusion</B></P><P>In conclusion, our study provides evidence that rs9642391C>G in the intron of <I>EGFR</I> is associated with <I>GBAS</I> expression and survival outcomes of patients with surgically resected early‐stage NSCLC.</P>

The complete mitogenomes of the oriental mayfly, Ephemera orientalis (Ephemeroptera: Ephemeridae) and the dragonfly, Davidius lunatus (Odonata: Gomphidae)

Eun Mee Lee,Mee Yeon Hong,Dong Young Kim,Ha Sik Shim,Hae Chul Park,Kee Young Kim,Ki-Gyoung Kim,In Hee Lee,Iksoo Kim 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.05

We determined the complete mitogenome of the oriental mayfly, Ephemera orientalis (Ephemeroptera: Ephemeridae) and the dragonfly Davidius lunatus (Odonata: Gomphidae). The 16,463-bp long E. orientalis and the 15,912 bp long D. lunatus mitogenome contains gene arrangement and content identical to the most common type found in a diverse insect order. Most individual E. orientalis and D. lunatus mt genes were well within the size found in the respective genes of other insects. The initiation codon for the D. lunatus COI gene was typical as ATA, whereas no typical start codon was found in the start region of E. orientalis COI gene. The A+T-rich regions of both mitogenomes have a few unusual feature. The A+T-rich region of E. orientalis contains a tandem repeat composed of two identical copies of 55 bp long, whereas that of D. lunatus contains a tandem repeat composed of duplicated identical 261-bp copies and one partial copy of the repeat. Also, the A+T-rich region of E. orientalis contains a single sequence and that of D. lunatus contains nine sequences, along with the tandem triplicate sequences, that has the potential to form stem-and-loop structures, flanked by the conserved sequences, “TA(A)TA” at the 5’ end and “G(A)nT’ at the 3’ end. Furthermore, the A+T-rich region of D. lunatus contains two tRNA-like structures, tRNALeu(UUR)-like sequence and tRNATyr-like sequence that have proper anticodon TAA and clover-leaf structure that were previously found in the hymenopteran insects.