건강식품 바이탈 및 비지놀의 抗疲勞 效果에 관한 연구

정경수,김혜경,김희수,김계양,곽영숙,김학범 충남대학교 약학대학 의약품개발연구소 1993 藥學論文集 Vol.9 No.-

As a result of extensive research efforts on the oriental medicinal herbs, some of their interesting biological activities have been elucidated. In the present study, antifatigue effects of two natural food supplements consisting of oriental herbs, Vital and Vigilor, were investigated using the ICR mice. The mice were fed with antibiotic-free normal mouse feed containing Vital or Vigilor for 14,28, or 31 days and then subjected to forced swim tests. In a test carried out in melting-ice water, Vital and Vigilor significantly increased the exhaustion times of the 28 day-fed mice by 26.9 % (p < 0.01) and 16.2% (p < 0.05), respectively. However, in the other test performed at 15±0.5℃ using 31 day-fed mice, Vigilor failed to increase the exhaustion time significantly (at p< 0.05), while Vital showed antifatigue effect by increasing the swimming time by 29.9% (p<0.01). Neither of Vital nor Vigilor exerted antifatigue effects in a swim test carried out on day 14 after the initiation of feeding. These results suggest that Vital and Vigilor exhert antifatigue effets when administered for a sufficient period of time by enhancing the health of the host animals.

무기고분자응집제를 이용한 조류의 응집제거

김규동,최영균,김희준,곽종운,정태학 대한상하수도학회 2002 상하수도학회지 Vol.16 No.5

An Experimental study was conducted for the removal of algae using various inorganic coagulants. Cultivation of algae, investigation of turbidity and chlorophyll-a removal efficiency according to the dosage of coagulants were conducted in series using a jar-tester in this study. Alum, PAC (Polyaluminum chloride), PAC-2 (Concentrated Polyaluminum chloride), PAC-Ca (PAC with Ca), PFC (Polyferricchloride) and PACS (Polyaluminum chlorinate silicate) with various SiO_2 content were used as coagulants. Algae grew up to about 1,500㎍ chlorophyll-a/l in 30 days. Cultivated algae was diluted to 150㎍ chlorophyll-a/l for the laboratory experiment. Decrease of pH was the lowest when PACS-5 was used as a coagulant, while it was the highest when PAC was used. Host of the coagulants showed high turbidity removal rate when the dosage was 1-3 mg Al/l. PFC showed stable turbidity removal efficiency and 80% of removal efficiency could be obtained when the dosage was 1.34 mg Fe/l. Among the coagulants, PACSs showed relatively higher removal efficiency of chlorophyll-a and it was the highest when PACS-5 was used. It means that inorganic coagulant including silicate is more advantageous in the removal of algae, and appropriate content of silicate on the basis of molar ratio of Al to Si is an important factor affecting the stability and settleability of the alum floc.

초등학교 여교사의 직무만족과 역할갈등 분석

김용주,이학주,정복희 경상대학교 2000 學生生活硏究所報 Vol.26 No.-

The purposes of this study were to examine the job satisfaction and role conflict of female elementary school teachers, and to analyze the relationship between those two factors. The following four research questions were raised. 1. What are the causal factors that brings about the job satisfaction of female elementary school teachers? 2. In regard to these causal factors, are there significant differences dependant upon such variables as teaching experience, the size of schools, and marital status? 3. What is the level of role conflict for married female elementary school teachers, and how significant are the differences according to the above variables? 4. What are the relationships between the job satisfaction factors and role conflicts of female elementary school teachers? For the purpose of this study, the researchers conducted questionnaire survey to the 300 female elementary school teachers in Kyong-nam Province. The study instrument is composed of 38 five-point Likert type questions. Major results of this research were as follows. First, the causal factors that bring about the job satisfaction of female elementary school teachers largely include school administration, a sense of recognition, promotions and raises, a physical environment, job duties, relationships with other teachers, meaningfulness of teaching, and working conditions. Second, the score on the job satisfaction of female elementary school teachers was above average(3.42 of 5.00). In regard to teaching experience, the respondents who have more than 20 years of experience had higer scores than the other groups of respondents. As for the size of schools, it was shown that schools with fewer than 23 classes had a relatively higher satisfaction rate than the other groups. Marital status had no significant differences. Third, the degree of the role conflict of married female elementary school teachers was low on the whole. Rather than the role conflict between home life and teaching duties as a teacher, the one as a housewife who has a job was greater. While teaching experience had no significant differences, the number of children had significant relations with female teachers role conflicts. Fourth, it was shown that the relationship between the causal factors of job satisfaction and role conflict of female elementary school teachers had no significant co-relationships.

침전성인자를 이용한 생물학적 고형물의 침전속도식과 고형물 플럭스 분석

김진우,최영균,이종훈,김희준,정태학 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

Equations on settling velocity of the activated sludge were developed by including sludge settleability parameters (SSP) and solids flux at a secondary settling tank was analyzed using the empirical equations, and an optimal solids loading rate was evaluated in this study. SVI, SSVI, DSVI and SSVI_3.5 were adopted as the SSP and a best fitting between observed and calculated zone settling velocity was obtained when SSVI_3.5 was used. Measured solids flux at the secondary settling tank was lower than that recommended by the national design criteria. Optimal solids loading rate and subsequent limiting solids flux can be derived if SSVI_3.5 is used instead of other SSP. Limiting solids flux calculated using SVI showed higher value than that calculated using SSVI_3.5 and the limiting solids flux could be better estimated when SSVI_3.5 was used because the calculated zone settling velocity using SSVI_3.5 was closer to the measured value.

제 2형 당뇨병 환자에서 혈중 Metalliproteinase-9의 농도

김상용,김희중,주유철,최동현,배학연 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Purpose : Diabetic nephropathy is a serious complication of diabetes and accounts for much of its morbidity and mortality. It is well known that the overt clinical phase of diabetic nephropathy is preceded for many years by the presence of microalbuminuria. Microalbuminuria is thought to be a marker of widespread vascular damage and may underlie the propensity toward severe extrarenal vascular disease in microalbuminuric patients. Metalloproteinase-9 has a broad substrate specificity for native collagens as well as proteoglycan and elastin. One study reported that an increased plasma metalloproteinase-9 concentration precedes the development of microalbuminuria in type 2 diabetic patients. Another study reported that a high glucose concentration cause a abnormality on the activity of metalloproteinase by the mesangeal cell. The purpose of the present study was to examine whether palsma metalloproteinase-9 concentrations are altered at various complications in type 2 diabetic patients. Methods : Sixty patients with type 2 diabetes and thirty healthy control were recruited for the present study. No patient had any malignancy or history of heart disease, liver disease, collagen disease. We recorded age, duration of diabetes, and blood pressure. After an overnight fast, blood was drawn from an antecubita1 vein of measurement of glucose, metalloproteinase-9, HbA1C, and serum creatinine. To measure plasma concentration of metalloproteinase-9, a one step sandwich enzyme immunoassay using two monoclonal antibodies was used. Patients were divided into two group according to the presence or abscence of microalbuminuria. The groups were then compared with regard to clinical and laboratory characteristics and serum concentration of metalloproteinase-9. Results : The mean serum levels of metalloproteinase-9 in diabetic patients (62.32±25.83ng/㎖) were significantly higher than in healthy controls(12.92±4.97ng/㎖) (p<01). The mean serum levels of metalloproteinase-9 in diabetic patients with microalbuminuria(81.16±41.43ng/㎖) were significantly higher than in those with normoalbuminuria(31.48±7.34ng/㎖) (p<01) and much more than in healthy control(12.92±4.97ng/㎖) (p<05). Furthermore, the severity of nephropathy were closely associated with the serum metalloproteinase-9 level and the serum metalloproteinase-9 level was significantly correlated with microalbuminuria. The mean serum level of metalloproteinase-9 in diabetic patients with retinopathy(61.74±39.07ng/㎖) was significantly higher than in those with no retinopathy(34.98±9.02ng/㎖) (p<05). But, in diabetic patients with normoalbuminuria, there is no difference between the groups with retinopathy versus no retinopathy. Conclusion : In summary, a sustained increase in serum metalloproteinase-9 in patients with type 2 diabetes is associated with a high risk for the development of microalbuminuria. The results of this study suggest that the serum rnetalloproteinase-9 was a useful and noninvasive marker for the development of diabetic nephropathy. It could be also used to predict the development of diabetic complications and to assess therapeutics or the prognosis of diabetes. The usefulness of this model will be clarified by a larger scale and serial study.

물리적 활성화에 의한 coffee char의 제조

김학희 선문대학교 첨단과학기술연구소 1999 첨단과학기술연구소 논문집 Vol.4 No.-

하이퍼-프리젠테이션 개념은 하이퍼-미디어 개념을 확장한 것으로, 동적으로 연출되고 있는 상황에서 링크개념을 설정하여 특정시점이나 지점에서 원하는 다음 정보를 보기 위해서 비순차적으로 연출할 수 있도록 하는 연출이다. 이러한 비순차적인 연출방법인 하이퍼-프리젠테이션 개념을 도입함으로써, 자유로운 멀티미디어 연출이 가능하게 되었지만, 이러한 동기화 방법에 의해서 혼합된 여러 프레젠테이션들간에는 일관성 문제가 발생할 수 있다. 본 논문에서는 하이퍼-프리젠테이션 명시 프로그램의 일관성 검증을 위해서 Petri Net을 이용한 하이퍼-프리젠테이션 명시 방법을 제시하고, 그것을 이용한 명시 프로그램의 일관성을 검증하는 방법을 제안한다. The concept of a hyperpresentation, as an extension of a hypermedia, is the presentation in which time-varying multimedia presentations are dynamically linked together and a hyperlink's context can be changed over time at any time during a continuous presentation. While this concept provides users with a flexible and powerful tool for their descriptions of the multimedia presentation, inconsistency problems in the synchronized presentations connected by hyper links can be introduced. This paper introduces a method of describing the hyperpresentation using Petri Net and proposes a methods of detecting inconsistent hyper link loop in the hyperpresentation description.

연속회분식 반응조를 이용한 슬러지 소화에서 포기비율과 포기빈도가 슬러지 소화에 미치는 영향

김성홍,김희준,최영균,정태학 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

Lab-scale sequencing batch experiments were carried out to investigate the effects of aeration ratio and aeration interval on nitrogen and phosphorus transformation during the sludge digestion by intermittent aeration. The highest nitrification and denitrification efficiency could be obtained when the aeration ratio was 0.25. Nitrification inhibition caused by alkalinity deficit was not observed at the aeration ratio of 0.75, however denitrification was limited at this level of aeration ratio. Biological phosphorus accumulation was possible at the aeration ratio of 0.25, however it was not observed when the aeration ratio was over 0.5. Under the same condition of aeration ratio, aeration interval played an important role in phosphorus release. Soluble phosphorus concentration of digested sludge was about 1.5㎎/L when the aeration interval was 4 hr and that was much lower than the concentration (12-18㎎/L) when the aeration interval was 20-44 hrs.

세라믹필터 역세정에 노즐 및 디퓨저 형상이 미치는 영향

김학빈,정재화,조형희 연세대학교 산업기술연구소 2001 논문집 Vol.33 No.1

The present study has been conducted experimentally to optimize the nozzle and diffuser shapes and diameters for dust removal system. Investigation of a dust removal system has been carried out to develop hot gas clean-up technology and to study for feasibility of clean coal technology pilot plant construction. Experiments was conducted to investigate the effects of pulse nozz1e and diffuser shapes on the air entrainments and on the pressure distribution in a particulate removal system. The main experimental parameters are different nozz1e shapes, nozzle diameters and nozzle tip positions from the diffuser upper plane. Especially, two different types of diffusers with a convergent-divergent shape and a divergent shape were tested systematically. Key words : IGCC(석탄가스화 복합발전), Ceramic Candle Filter(세라믹 캔들 필터), Reverse Cleaning(역세정). Nozz1e(노즐), Diffuser(디퓨저), Entrainment Ratio(동반류비)

韓國産 穀物에서의 trichothecene mycotoxin 生成에 關한 硏究

김학성,민봉희 대구대학교 기초과학연구소 1988 基礎科學硏究 Vol.5 No.-

This study was carried out to investigate the trichothecene mycotoxin productivity of Fusarium tricinctum NRRL 3229. F. tricinctum was cultured on cereal grains at temperature from 10℃ to 15℃ for 4 weeks. Toxins were extracted with solvent and purified partially by column chromatography. The amounts of T-2 toxin, HT-2 toxin, diacetoxyscirpenol and T-2 tetraol were quantitated by gas-liquid chromatography. Corn and millet had the highest productivity of trochothecene mycotoxin. The highest levels of T-2 toxin and HT-2 toxin were produced on corn and maximal yield of T-2 tetraol was obtained in cultures on millet. However, no detectable amount of diacetoxyscirpenol was observed in this experiment. Metabolism of T-2 toxins showed high differences among cereal grains. T-2 toxin was metabolized easily into HT-2 toxin in corn, polished rice, glutinous rice, and sorghum and metabolized very slowly into T-2 tetraol toxin. However, T-2 toxin in unpolished rice was metabolized into HT-2 toxin and T-2 tetraol. Also, T-2 toxin was metabolized rapidly into HT-2 toxin and T-2 tetraol in barley, wheat, millet and red bean while T-2 toxin in unpolished rice was metabolized very slowly into HT-2 toxin and T-2 tetraol.

두부 손상이 골절 칭 촉진 시동물 모델 및 유전자 발현 분석

김경희,김학선,문성환,김향,권언해,이환모,박희완,한수봉,문은수 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2