열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

DARC방송을 이용한 교통정보의 실시간 처리 시스템 구현

하동문(Dong-Mun Ha),서재홍(Jae-Hong Seo),김용득(Yong-Deak Kim) 대한전자공학회 1998 대한전자공학회 학술대회 Vol.1998 No.6

Remediation of arsenic-contaminated tailings by chemical extraction

하동윤(Dong Yun Ha),조순행(Soon Haing Cho),이상은(Sang Eun Lee),최휘문(Whee Mun Choi) 대한환경공학회 2005 대한환경공학회 학술발표논문집 Vol.2005 No.12

비젼 기반 차량 검출 및 교통 파라미터 추출

하동문(Dong Mun Ha),이종민(Jong Min Lee),김용득(Yong Deak Kim) 한국정보과학회 2003 정보과학회논문지 : 시스템 및 이론 Vol.30 No.11·12

다양한 그림자는 비젼 기반 차량 검출에서 오류를 발생시키는 주요 원인이다. 본 논문에서는 노면 표시 기반 방법과 배경 빼기 및 에지(BS & Edge) 방법이라는 두 가지 방안을 차량 검출과 그림자 제거를 위해 제안하였다. 노변의 지형 지물들로 인해서 발생하는 그림자의 영향이 크게 증가하는 상황에서의 실험을 통해서 96% 이상의 차량 검출 정확도를 나타냄을 확인하였다. 전술한 두 가지 방법을 기반으로 하여, 차량 추적, 차량 계수, 차종 분류, 그리고 속도 측정을 수행하여 각 차로의 부하를 나타내는 데 사용되는 차량 흐름과 관련된 여러 가지 교통 파라미터를 추출하였다. Various shadows are one of main factors that cause errors in vision based vehicle detection. In this paper, two simple methods, land mark based method and BS & Edge method, are proposed for vehicle detection and shadow rejection. In the experiments, the accuracy of vehicle detection is higher than 96%, during which the shadows arisen from roadside buildings grew considerably. Based on these two methods, vehicle counting, tracking, classification, and speed estimation are achieved so that real-time traffic parameters concerning traffic flow can be extracted to describe the load of each lane.

선별등재 제도에 대한 전문가와 제약회사의 인식도 비교분석

하동문(Dong Mun Ha),이수경(Su Kyoung Lee),김대업(Dae Up Kim),정규혁(Kyu Hyuck Chung),이의경(Eui Kyung Lee) 대한약학회 2010 약학회지 Vol.54 No.4

The Positive List System was newly introduced in South Korea as of January 2007. This study aims to survey and compare perception of and attitudes toward the Positive List System in the process of new drug listing that health professionals and pharmaceutical companies have. 50 professionals and 52 companies answered the questionnaire regarding health policy environments, policy decision/enforcement process, policy effects and satisfaction related to introducing the Positive List System. SAS 9.1 was used for statistical analyses. The results showed that participants had the general sympathy with health policy environments for the introduction of the Positive List System into South Korea. However, the response rates of policy decision/enforcement process and effects were negative and these tendencies were more striking in pharmaceutical companies. As for policy satisfaction, participants marked positive responses more than negative ones. It is necessary to remedy and supplement problems with policy decision/enforcement policy and effects revealed in this study and to improve the Positive List System through gathering opinions among groups and organization concerned.

Recommendation for the establishment of a poison control center at the Korea Disease Control and Prevention Agency

Dong-Uk Park,Jiwon Kim,Minwoo Nam,Eunchan Mun,Yesung Lee,Kwonchul Ha,Sangjun Choi,Won-Jun Choi,Jihoon Park,Hyoungbae Jun,Soyoung Park 환경독성보건학회 2020 환경독성보건학회지 Vol.35 No.3

There is currently no governmental body in South Korea resembling the type of poison center (PC) recommended by the World Health Organization (WHO). All Organization for Economic Cooperation and Development (OECD) member countries except for South Korea maintain such a PC tasked with both preventing poisoning accidents and supporting the prompt treatment of poisoned patients. Such a PC could very possibly have allowed the country to more promptly recognize the widespread wave of humidifier disinfectant (HD) associated health effects, including fatal lung injury and death, that lasted started roughly in 2000 and continued through 2011. Despite this chemical poisoning tragedy, South Korea still lacks a surveillance system to monitor health effects caused by the use and consumption of materials that include products containing chemicals, foodborne pathogens, drugs, pesticides, etc. There have been no legal procedures for examining the potential risk of products or materials manufactured by industry. The reporting of national poisoning data or causes of poisoning, which is near ubiquitous in advanced countries with a PC, has not taken place We recommend that a PC should be established within the Korea Disease Control and Prevention Agency (KDCA). In addition, in order to perform surveillance of poisoning cases across the country, a certain number of regional PCs, including at large hospitals, will also be necessary.

Detection of Calibration Patterns for Camera Calibration with Irregular Lighting and Complicated Backgrounds

Dong-Joong Kang,Jong-Eun Ha,Mun-Ho Jeong 대한전기학회 2008 International Journal of Control, Automation, and Vol.6 No.5

This paper proposes a method to detect calibration patterns for accurate camera calibration under complicated backgrounds and uneven lighting conditions of industrial fields. Required to measure object dimensions, the preprocessing of camera calibration must be able to extract calibration points from a calibration pattern. However, industrial fields for visual inspection rarely provide the proper lighting conditions for camera calibration of a measurement system. In this paper, a probabilistic criterion is proposed to detect a local set of calibration points, which would guide the extraction of other calibration points in a cluttered background under irregular lighting conditions. If only a local part of the calibration pattern can be seen, input data can be extracted for camera calibration. In an experiment using real images, we verified that the method can be applied to camera calibration for poor quality images obtained under uneven illumination and cluttered background.

Pathological Study on Interstitial Pneumonia in Korean Native Goats

Ha-Hyun Kim,In-Jin Hwang,Su-Jin Park,Sang-Ik Park,Young-Ju Jeong,Mun-Il Kang,Bang-Hun Hyun,In-Joong Kim,Dong-Kun Yang,Chang-Hee Kwon,Kyoung-Oh Cho 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.4

The interstitial pneumonia of animal and human can be induced by various factors throughout the aerogenous and hematogenous routes. Although the causative agents of the interstitial pneumonia in the sheep and goats are known to be usually infectious agents, its prevalence in the Korean native goats is not well studied in South Korea. Therefore, pathological examination of interstitial pneumonia whose causative agents were unknown was performed with four neonatal goats obtained from four farms. These goats showed progressive depression and anorexia. At necropsy, diffuse depression of all lung lobules with some patch normal lobules were observed. On the cut surface, visible exudates were not observed in airways except for one case who had mild foamy materials in the bronchioles and bronchi. The pulmonary parenchyma had a meaty appearance. Histologically, alveolar walls were thickened by prominent hyperplasia of type Ⅱ pneumocytes with some macrophages. The lining epithelia of the bronchioles and bronchi were intact. From these results, these cases were diagnosed as interstitial pneumonia in the Korean native goats. Since many infectious agents cause interstitial pneumonia with the infiltration of lymphoid cells into alveolar wall and peribronchial regions, the findings observed in the present cases suggest the possibility that these pulmonary lesions may not be caused by infectious agents. Therefore, further studies will need to find out the precise causative agents from the lung lesions in the affected goats.

일개 종합병원에서 최근 5년간 의료종사자들의 주사침 자상에 관한 연구

하경임,김문연,이동욱,정휘수 동국대학교 의학연구소 2009 東國醫學 Vol.16 No.1

병원의 업무와 관련된 상해는 오염된 주사바늘에 의한 주사침 자상(needle-stick injury)이 가장 흔하다. 이는 B형 간염, C형 간염, 후천성면역결핍증 등과 같은 혈액 전파 감염성질환의 위험을 증가시켜 의료종사자들에게 심각한 위험이 된다. 동국대 경주병원에서 최근 5년간 주사침 자상을 보고한 직원들은 49명 이었는데 48명 (97.9%)이 날카로운 주사침이나 의료기구에 찔려서 발생되었다. 이들 중 83.7%는 5년 이하의 근무경력자이었고 간호사가 49.0% 인턴 28.6% 전공의 14.3% 임상교수 6.1% 간호조무사가 2.0% 였다. 주사침 자상의 발생 경위는 직접 의료행위를 하거나 시행하면서 발생한 예가 87.8% 였고 나머지 12.2%는 의료기구를 정리하는 과정에서 발생하였다. 주사침 자상이 발생한 직원돌의 95.9%는 본인의 B형 간염 항체 유무에 대하여 제대로 알고 있었고, 75.5%는 B형 간염 예방접종 과거력이 있었다. 본원에서 주사침 자상에 의해 혈액전파감염성질환에 이환된 예는 없었다. 이는 직원감염 예방에 대한 본원의 적극적인 감염관리프로그램의 효과로 생각되며, 향후 주사침 자상 예방에 대한 교육과 흥보를 지속적으로 시행하여야 할 것이다. Needlestick injury by contaminated needles is the most common hospital related injury. This elevates the risks, of blood transmitted disease such as hepatitis B, hepatitis C, AIDS and can be a serious threat health care workers. In dongguk university gyeongju hospital, out of 49 needle sticks in a recent 5 years study, 48(97.9%) cases were due to injuries by sharp needles or medical equipments. The 83.7% of those were under 5 years of experience. Out of those cases 49% were nurses, 28.6% were interns, 14.3% were residents, 6.1% were clinical professors, and 2.9% were assistant nurses. Their activities associated with needlestick injuries was as follows; 87.8% of those occurred during medical practices and 12.2% during organizing medical equipments. Among of our hospital personnels who had needle stick injuries, 95.9% accurately knew of their prevalence of hepatitis B antibody and 75.5% had history of hepatitis B vaccination. There were no cases of blood transmitted disease due to needlestick injuries in our hospital. This is thought to be due to an active infection control program, and continuous eduction for occupational hazards of hospital personnel is needed to prevent needlestick injuries.

Pathological Study on Purulent Pneumonia in Korean Native Goats

Ha-Hyun Kim,In-Jin Hwang,Su-Jin Park,Sang-Ik Park,Young-Ju Jeong,Mun-Il Kang,Bang-Hun Hyun,In-Joong Kim,Dong-Kun Yang,Chang-Hee Kwon,Bong-Joo Lee,Kyoung-Oh Cho 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.4

Bacteria belonging to the family Pasteurellaceae cause a common and economically important pneumonia to ruminants, particularly in temperate climates. However, bacterial pneumonia in the Korean native goats are not well studied in South Korea. Therefore, pathological examination of bacterial pneumonia was performed with two young goats obtained from two farms. These goats showed progressive dyspnea, depression and anorexia. At necropsy, cranioventral lobes which attached to pleural wall by fibrin were patch purple-red or white, and hard. Histopathologically, alveoli and small bronchioles were filled with variable proportions of necrotic neutrophils, fibrin, edema fluid and cellular debris. In some aggregates of necrotic neutrophils, there were streaming of oat-shaped cells with pale basophilc chromatin. From these results, these cases were diagnosed as purulent cranioventral bronchopneumonia. Since Mannheimia Haemolytica and Histophilus somni within the family Pasteurellaceae causing cranioventral bronchopneumonia are known to cause necrosis of neutrophils and oat-shaped cells infiltrating in the lung lesions, these cranioventral bronchopneumonia might be caused by these bacteria. Therefore, further studies will need to isolate precise causative bacterium from the lung lesions in the affected goats.