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유산균(L.lactis CBT-8)및 발효 추출물의 Helicobacter pylori 억제 능력
진춘조,박형석,이혜운,김성렬,강동구,이준상,이재동,왕준호 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-
Helicobacter pylori infection was the cause of chronic gastritis, duodenal ulcer and gastric MALT lymphoma. The eradication rates of H. pylori using antibiotics are around 80%. Lactobacilli have been demonstrated to have in vivo and in vitro inhibitory effects on H. pylori infection. We aimed to evaluate the inhibitory effect of L. lactis CBT-8 and its extract on H. pylori in human stomach. Thirty-five H. pylori-infected volunteers(30-49 yr)were randomized into two groups which were treated with L. lactis CBT-8 and its extract(Group A n=17) or milk containing L. lactis CBT-8(Group B, n=18). They underwent 13C-urea breath tests before and after treatment. The DOB30 of group A(n=14) was decreased 41.0% after treatment(26.0±4.9 before, 15.3±2.1 after treatment)(p<0.05). the DOB30 of group B(n=13) was decreased 22.3% after treatment(22.0±2.2 before, 17.1±1.7 after treatment)(p<0.05). In conclusion, L. lactis CBT-8 was effective in suppressing H. pylori infection in human stomach.
강기춘,이청희,왕수환,이천일,표형배,정노희 한국공업화학회 2004 응용화학 Vol.8 No.1
Nowadays many products using nano-technology have been released and nano-technology would be more prospected in all kinds of industries especially cosmetic manufacturing and ingredient fields. In cosmetics, the saturated lecithin, one of the main surfactants to make liposome, has been used for its stability but it has been substituting by unsaturated lecithin which has excellent skin affinity and penetration. So we studied to develop nano-liposome below 50㎚ with unsaturated lecithin. To make stable nano-liposome, many factors including solvent like propylene glycol, pH balance, homogenizing pressure and liposome stabilizer like surfactant are important especially stearate series surfactants have positive effect in liposome size and long term stability. But in liposome with saturated lecithin, surfactant has negative effect and appropriate amount of oil should be used to be stable. So we could conclude that unsaturated lecithin is suitable than saturated lecithin to make nano-liposome.
다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예
최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-
Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.
Wang, Hui-Chun,Li, Bao-Lin,Zheng, Yan-Jun,Wang, Wen-Ying Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.9
Mesoporous carbons with tailored pore size were prepared by using sucrose as the carbon source and silicas as the templates. The silica templates were obtained from a hydroxypropyl-${\beta}$-cyclodextrin-silica hybrids using ammonium perchlorate oxidation at different temperatures to remove the organic matter. The structures and surface chemistry properties of these carbon materials were characterized by $N_2$ adsorption, TEM, SEM and FTIR measurements. The catalytic performances of these carbon materials were investigated through the reduction of nitroaromatic using hydrazine hydrate as the reducing agent. Compared with other carbon materials, such as active carbon, and carbon materials from the silica templates obtained by using calcination to remove the organic matter, these carbon materials exhibited much higher catalytic activity, no obvious deactivation was observed after recycling the catalyst four times. Higher surface area and pore volume, and the presence of abundant surface oxygen-containing functional groups, which originate from the special preparation process of carbon material, are likely responsible for the high catalytic property of these mesoporous carbon materials.
Chun-Yan Wang,Mengqi Zhang,Huan Li,Na Wang 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.10
An event-triggered adaptive tracking control problem is investigated for a class of switched nonstrictfeedback nonlinear systems with unknown control directions and switching signals. With a linear observer, the output feedback stabilization is achieved under arbitrary switching. The key advantages of the proposed control strategy are that the tracking prescribed performance is ensured regardless of the unknown control directions. Only one tuning parameter needs to be estimated during the recursive process. Moreover, with a varying threshold, a common event-triggered mechanism is developed. Based on the Lyapunov stability theory and the dynamic surface backstepping technique, the developed control method theoretically proves that under arbitrary switching, all signals of the resulting closed-loop switched system are bounded and the tracking error can converge to a small neighborhood of the origin within the prescribed bounds. The Zeno behavior is also avoided. The effectiveness and feasibility are demonstrated by two examples.
Chun Yan Wang(왕춘연),Chung Ha Lee(이청하),Mi Ra Lee(이미라),Beom Sik Yun(윤범식),Lei Liu(유뢰),Zhen Wang(왕젠),Zhe Ming Fang(방철명),Dong Liang Zhang(장동량),Zheng Li(이정),Chang Keun Sung(성창근) 한국생명과학회 2010 생명과학회지 Vol.20 No.5
본 논문은 선충 포식성 곰팡이에 대한 선충의 영향을 조사한 연구로, 소나무 기생곰팡이인 E. vermicola에 미치는 소나무 선충의 영향을 체계적으로 분석하였다. 선충 대사물과 선충 균질액 모두 E. vermicola의 성장을 빠르게 촉진하였으나, 선충 대사물이 선충 균질액보다 약간 높은 효과를 보였다. 또한 소나무 선충이 생성하는 휘발성 물질이 E. vermicola 성장에 미치는 영향을 분석하는 새로운 실험방법을 개발하였다. 본 연구결과에 따르면, 선충의 휘발성 물질은 E. vermicola에 아무런 영향을 끼치지 않는다는 재현성 있는 결과를 도출하였다. 본 연구는 소나무 선충의 생물학적인 조절인자로서 E. vermicola을 적용할 수 있는 정보를 제공할 수 있을 것이다. The influence of nematodes on nematophagous fungi has seldom been investigated. In the present study, the influence of pinewood nematode on its endoparasitic fungus, Esteya vermicola, was investigated systemically. Although both nematodal metabolite and nematodal homogenate could stimulate and speed up the growth of E. vermicola, the impact of nematodal metabolite was slightly higher than that of nematodal homogenate. In addition, a method was developed to investigate the influence of volatiles, discharged by pinewood nematodes in their metabolic process, on the growth of E. vermicola. Reproductive results were given and confirmed that nematodal volatiles have no influence on the cell growth of E. vermicola. This study may provide information for the application of E. vermicola as biological control agent of pinewood nematode.
Wang, Tao,Yun, Yanbin,Wang, Manxiang,Li, Chunli,Liu, Guicheng,Yang, Woochul Elsevier 2019 JOURNAL- TAIWAN INSTITUTE OF CHEMICAL ENGINEERS Vol.105 No.-
<P><B>Abstract</B></P> <P>To solve the problems of membrane material tolerance and membrane fouling, a micro/nano hierarchial structure with low surface energy was constructed above the exterior surface of a ceramic hollow fiber membrane using ZnO nanorod arrays and 1H,1H,2H,2H-perfluorodecyltriethoxysilane (PDTS) coatings, which make it superhydrophobic and self-cleaning. The surface morphology, chemical functional groups, and water contact angel of the modified membranes were identified. The results show that large quantity of ZnO nanorods possess desirable characteristics (<I>i.e.</I> superhydrophobicity, exceptional thermal and mechanical stability, and water contact angle of 160.12°) were detected on the ceramic membrane. The novel membrane shows excellent self-cleaning performance and good desalination ability in the utilization of vacuum membrane distillation (VMD) system for high-salinity water desalination.</P> <P><B>Highlights</B></P> <P> <UL> <LI> • Ceramic membrane is modified by imitating of superhydrophobic biological surfaces. </LI> <LI> • The micro/nano hierarchical structure with low surface energy endows the superhydrophobicity. </LI> <LI> • The P-ZN-CHF membrane obtains antifouling ability. </LI> <LI> • The modified membrane shows excellent performances during vacuum membrane distillation. </LI> </UL> </P>