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      • 반려동물의 기생충검사 이론 및 실제

        이성호,박영석,박병권,김상기,정지윤,박수진,박창식,김병수 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

        The aim of this article is to improve human health and that of companion animals by improving the diagnosis and control of parasitic diseases. This is achieved by research into parasites of veterinary significance including zoonoses and the use of comparative systems to increase our understanding of some human parasitic diseases. We should promotes learning and teaching through knowledge and operates a diagnostic unit that offers a service to pet owner for indigenous and exotic parasitic diseases of companion animals. We must diagnose and treat them early. Zoonotic parasites are very important because many of animal parasites are zoonoses and give pain and death to human. Parasites are divided Protozoa, Helminthes and Arthropods. There are many protozoa, about 65,000 species. Arthropods are the vector of another diseases, such as virus, bacteria, protozoa and nematodes. Helminthes are composed of Trematoda, Cestoda, Nematoda and Acanthocephala. The target of Veterinary Parasitology is to recognize the characteristics of these parasites and subsequently diagnose, treat and control them. This article is intended to familiarize you with the essential facts and concepts of companion animal parasitology. Emphasis is placed on fecal sample techniques (comparison of fecal examination techniques; frequently found artifacts in fecal smears; direct Smear; zinc sulfate flotation; etc.) We recommend that the study be done to more references on animal parasites.

      • KCI등재
      • Cadmium과 Di-(2-ethylhexyl) Phthalate에 의한 고환 독성 : 아연과 Apoptosis의 역할 The Role of Zinc and Apoptosis

        권민,최병선,박언섭,홍연표,박정덕 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.1

        Cadmium (Cd) and di-(2-ethylhexyl) phthalate are used widely and distributed ubiquitously in the environment, which are well-known reproductive toxicants. DEHP and/or Cd causes the apoptosis, degeneration of spermatogenic cells, and massive necrosis, resulting in testicular atrophy. Zinc is an essential metal in spermatogenesis, the zinc concentration in testis is changed in DEHP- or Cd-treated animals. However, the role of zinc or apoptosis in testicular toxicity by DEHP or Cd has not been understood well. In this study, Sprague-Dawley male rats were given DEHP (2 g/kg, 5 ml corn-oil, PO) or Cd (CdCl₂2 mg/kg, 4 ml saline, sc) for 1, 2, 7 and 14 days. Control rats were given vehicle corresponding to each group. At day 1, 2, 7, and 14 after administration of DEHP or Cd, the morphological findings including apoptosis in testes were observed under the light microscope, and the zinc concentrations in testes were determined by atomic absorption spectrometry with flame method. Fas and FasL mRNA in testes were analyzed by RT-PCR method at 12 hours, 1, 7, 14 days after adminstration of DEHP or Cd. Absolute and relative testicular weight were lower in DEHP- or Cd-treated rats than control. DEHP or Cd produced morphological changes in testes, including apoptosis, degeneration, necrosis and massive loss of spermatogenic cells, resulting in testicular atrophy. The zinc concentration in testes was not different at day 1 after administration of DEHP, but was decreased at later times. Testicular zinc was lower at day 1, 2 in Cd-treated rats than control, but was higher at 7, 14 days after Cd administration. The levels of Fas and FasL mRNA were highly expressed in testes after administration of DEHP or Cd. These results suggest that the change of zinc level in testes might be a secondary effect of DEHP- or Cd-induced testicular toxicity, and Fas signal system might be play an important role in pocessing of apoptosis in testes by DEHP or Cd.

      • 병원폐기물중 폐합성수지류의 물성 및 세척·선별에 관한 기초연구 : 폐주사기와 폐수액세트를 중심으로

        권기홍,성병주,박종웅 慶山大學校 環境시스템開發硏究所 1999 環境硏究 Vol.4 No.1

        This research was carried out basic study to effective manage and develop washing-separator system for plastics in hospital wastes. The results are as follows : In 1995, the generation rate of plastics in hospital waste was 6,666ton in total amount of 11,195ton. Most of syringe was PP and the composition of drainage set was PP, PVC and ABS. Therefore, separation of syringe is better than that of drainage set. Pathoganic microbes in syringe was positive before sterilization process, but became negative after that process, Pollution of syringe-washing water was increased as washing times increased and optimum washing to obtain good pellet was 6 times. Separation efficiency differed with content of injected rubber in the manufactory process of syringe makers. Remaining rubber in pellet was completely removed by the final separator developed during the this project, so we obtained good PP pellet.

      • 간암세포에서 저산소증에 의해 유도되는 VEGF의 발현기작에 대한 연구

        권유욱,배수경,김정애,김규원,박병채 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

        Purpose: Hepatocellular carcinoma(HCC),a typical hypervasculized tumor is very sensitive to hypoxia and vascular endothelial growth factor(VEGF) has previously been identified to be up-regulated in response to hypoxia in several cell types. However, the molecular mechanisma by which hypoxia is sensed by the cells remain enigmatic. To investigate whether calcium and AP-1 are involved in hypoxia-sensing mechanism, we performed following eaperiments. Materials and Methods: Hep3B cells were grown in hypoxia condition. To assess cell viability, MTT assay was performed. To investigate the effect of calcium and AP-1,northern blot analysis was performed after treatment with BAPTA/AM. Results: The expression of VEGF was significantly up-regulated by hypoxia in Hep3B, hepatocellular carcinoma cell line. The increased expression of VEGF induced by hypoxia was blocked by the addition of BAPTA/AM, a cytosolic calcium chelator to the media. In addition, we found that the expression of c-jun protooncogene was also-regulated by hypoxia. Hypoxia increase of c-jun expression was also normalized by the treatment with BAPTA/AM. Conclusion: These results suggest that the increased expression of VEGF by hypoxia is mediated through the calcium and c-jun signalling pathway in the Hep3B human hepatoma cell lines.

      • 사용자 스키마와 규칙을 이용한 웹 정보 추출

        박병권 동아대학교 정보기술연구소 2006 情報技術硏究所論文誌 Vol.14 No.1

        To query the vast amount of web pages which are available in the Internet, it is necessary to extract the encoded information in the web pages for converting it into structured data (e.g. relational data for SQL) or semistructured data (e.g. XML data for XQuery). In this paper, we propose a new web information extraction system, PIES, to convert web information into XML documents. PIES is based on a user-specified schema and HTML tag pattern descriptions. The web information is extracted by the pattern descriptions and validated by the schema. We designed a new language to describe extraction rules, and a new regular expression language to describe HTML tag patterns. We implemented PIES and applied it to the US patent web site to demonstrate its feasibility. It successfully extracted more than thousands of US patent data and converted them into XML documents.

      • 마이크로 그루브 가공의 특성 평가

        권동희,박진효,김정석,김병민,정융호,강명창 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

        As demands for micro parts are on the increase in recent industries such as aerospace, biomedical, electronics, environment, information technology and display, the need for manufacturing such parts is also increasing. Major methods of manufacturing micro parts are based on semiconductor process technology such as lithography and etching and non-traditional machining using lasers, ultrasonic, ion-beams or electrical discharge. However, these methods require lots of time, workpiece materials are limited, and such methods are only applicable to the machining of two-dimensional shapes. Therefore, mechanical machining methods are required for the manufacturing of micro parts with complex shapes. This paper presents an investigation on the characteristics for micro groove machining by using the ultrahigh-speed air turbine spindle, and verifies the properties of mechanical method in fabricating molds for micro barrier ribs. As a result, the optimal machining condition could be found from the investigation of surface roughness according to the kinds of burr shapes in the fabricating of iron mold by using micro endmill.

      • 하수슬러지의 건설재로의 이용 타당성에 관한 연구

        권재혁,박병수 三陟大學校 1999 論文集 Vol.32 No.2

        Feasibility of using the mixture of a wastewater sludge and additive as liner and the cover materials in disposal landfill. Granite weathered soil flyash, produced as a by-produced as a by-product in the power plant, were used as the primary additives to improve geotechnical engineering properties of sludge. For secondary additives, bentonite and cement were mixed with sludge to decrease the permeability and to increase the shear strength, irrespectively. Various kinds of laboratory test, required to evaluate the design criteria for the liner and the cover materials, were carried out by changing the mixing ratio of sludge with the additives. Basic soil property tests of specific gravity, grain size distribution, the liquid and the plastic limits were performed to evaluate their properties and to analyze their effects on permeability, compaction of mixtures. Various test results with mixtures were assessed to evaluate whether their properties met the requirements as the liner and the cover materials in waste disposal landfill.

      • CAD를 이용한 양수장 및 배수장설비 설계의 표준화

        권병철,권경우,김기길,명태식,박찬호,박귀용 한밭대학교 산업과학기술연구소 1995 논문집 Vol.3 No.-

        This paper is to be illustrated automation in the design of Pumping Station and Draining Station. Program for design automation applying Auto LISP, DCL can be used to design and draw simultaneously. The study result are as follows. 1. Optimal design has been introduced and precise design has been possible using CAD. 2. Dialog design is possible with introduction the concept of design automation, and design cost can be reduced greatly.

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