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      • 갑상선 결절에 대한 세침흡입 세포검사의 수술전 진단적 가치

        전병민(Byeong Min Jeon),이병욱(Byeong Wook Lee),김상효(Sang Hyo Kim),백낙환(Nak Whan Paik) 대한두경부종양학회 1994 대한두경부 종양학회지 Vol.10 No.2

        Since 1950s, fine needle aspiration(FNA) cytology has become increasingly popular and numerous reports have demonstrate its accuracy, safety and cost-effectiveness. To evaluate the role of diagnostic FNA cytology in the thyroid nodule, authors compared preoperative cytologic findings with postoperative histologic diagnosis in two hundred two thyroid nodules underwent surgical resection at Department of Surgery, Pusan Paik Hospital. from July 1990 to December 1993. FNA and thyroidectomy was performed primarily by one Head and Neck surgeon and specimen was interpreted by several pathologists. One hundred seventy two FNAs(85%) were interpreted as positive for benign lesion or carcinoma and thirty(15%, cystic in 25, non-cystic lesion in 5 cases) were unsatisfactory specimens for interpretation. The preoperative cytologic diagnosis of 172 cases revealed 'benign' in 112. 'suspicious cancer' in 10 and 'cancer' in 50 cases. Postoperative pathologic diagnosis showed 'nodular goiter' in 64. 'benign tumor' in 43, 'thyroiditis' in 4 and 'cancer' in 61 cases. The value of preoperative FNA diagnosis for thyroid cancer yielded a sensitivity of 85.2%, a specificity of 92.7%, false negative rate 5.2%, false positive rate 4.5% and positive predictive value and overall accuracy were 86.6% and 90.1% respectively. Preoperative rate of malignancy could be increased up to 35.5% by using FNA.

      • Impact of the attainment of current recommended low-density lipoprotein cholesterol goal of less than 70 mg/dl on clinical outcomes in very high-risk patients treated with drug-eluting stents

        Kim, Byeong-Keuk,Kim, Dong Whan,Oh, Seungjin,Yoon, Se-Jung,Park, Sungha,Jeon, Dong Woon,Yang, Joo Young Lippincott Williams Wilkins, Inc. 2010 Coronary artery disease Vol.21 No.3

        OBJECTIVE: We sought to evaluate whether the attainment of low-density lipoprotein cholesterol (LDL-C) goal of less than 70 mg/dl would affect clinical outcomes in Korean patients treated with drug-eluting stents (DES). BACKGROUND: The current cholesterol guideline has strongly recommended reducing LDL-C to less than 70 mg/dl as the goal of therapy for very high-risk patients. METHODS: From 2003 to 2006, a total of 1347 very high-risk patients were treated with DES. Among them, we identified 578 eligible patients with follow-up LDL-C within 6–8 months after DES and divided these patients into two groups based on the level of follow-up LDL-C: group A, follow-up LDL less than 70 mg/dl (n=234) and group B, LDL of at least 70 mg/dl (n=344). Then we analyzed the incidence of major adverse cardiac and cerebrovascular events [MACCE: death, myocardial infarction, target-vessel revascularization (TVR), non-TVR, cerebrovascular accidents] of both the groups. RESULTS: During the follow-up (mean duration=30±10 months), group A showed a significantly lower TVR (6%) and MACCE rate (14%), compared with group B (TVR: 12%, P=0.032; MACCE: 24%, P=0.002). However, there was no difference in the rate of death, myocardial infarction, or cerebrovascular accidents between the two groups. By multivariate analysis, follow-up LDL-C level of less than 70 mg/dl was one of the significant predictors for the occurrence of MACCE (odds ratio=0.39, 95% confidence interval: 0.21–0.72, P=0.003) or TVR (odds ratio=0.39, 95% confidence interval: 0.20–0.76, P=0.005). CONCLUSION: This study showed that the attainment of LDL-C goal of less than 70 mg/dl was significantly associated with a lower MACCE or TVR rate in very high-risk Korean patients treated with DES.

      • KCI등재후보

        우측 신 탈장을 동반한 성인형 Bochdalek 탈장 1례

        고병성(Byeong Seong Ko),김도형(Do Hyung Kim),배장환(Jang Whan Bae),전현정(Hyeon Jeong Jeon),최강현(Kang Hyeon Choe) 대한내과학회 1998 대한내과학회지 Vol.54 No.4

        Bochdalek hernia through Bochdalek foramen, defect at the posterolateral side of the diaphragm is one of the congenital diaphragmatic hernias. It usually occurs in infants, but very rare in old age and also on the right side. We experienced the right-side Bochdalek hemia including kidney herniation in 68 years old man manifested by hernoptysis. CT scan revealed diaphragmatic defect and herniated liver, colon and kidney. Thoracotomy was performed and the 10 cm-sized large defect was closed with patch. After then, the patient has been well without symptom. Bochdalek hernia through Bochdalek foramen, defect at the posterolateral side of the diaphragm is one of the congenital diaphragmatic hernias. It usually occurs in infants, but very rare in old age and also on the right side. We experienced the right-side Bochdalek hemia including kidney herniation in 68 years old man manifested by hernoptysis. CT scan revealed diaphragmatic defect and herniated liver, colon and kidney. Thoracotomy was performed and the 10 cm-sized large defect was closed with patch. After then, the patient has been well without symptom.

      • KCI등재

        급냉 연속 주조된 페라이트 스테인레스강 판재의 조직 및 인장성질에 미치는 Cr 함량의 영향

        오명석,전병완,이태행,조성석 ( Myeong Suck Oh,Byeong Whan Jeon,Tae Haeng Lee,Seong Seock Gho ) 한국주조공학회 1988 한국주조공학회지 Vol.8 No.1

        Using the twin-roller type melt-quenching technique, we investigated the effect of Cr content on the microstructure and tensile properties of ferritic stainless steels, whose thickness is 0.5㎜ has been investigated. In this experiment, the three kinds of ferritic stainless steels has been used. The predicted cooling rates of melt-quenched ferritic stainless steels were not changed, even the Cr content increases up, to 25%. The metastable phase of the melt-quenched ferritic stainless steels were changed depending upon the car Cr content. In case of 17% Cr steel, the metastable phase was martensite and in case of 20 and 25% Cr steel, the metastable phase was austenite. After heat treatment, the tensile properties of the melt-quenched stainless steels are better than those of conventional ferritic stainless steels.

      • SCOPUSKCI등재

        혈압이 떨어질 정도의 심한 장출혈을 보인 크론병 1예

        박선미,배장환,고병성,전현정,이상전,김도형,윤세진 대한소화기내시경학회 1998 Clinical Endoscopy Vol.18 No.2

        Life-threatening gastrointestinal hemorrhage is a rare complication in Crohn's disease. The authors experienced a case of Crohn's disease manifested with massive lower intestinal bleeding. A 22-year-old woman, who had underwent small bowel resection for bowel perforation and intestinal fistula, was admitted with lower abdominal pain and massive hernatochezia. A radioisotope bleeding scan and mesenteric angiography revealed suspi- cious intestinal bleeding in the small bowel area. The colonoscopy showed multiple shallow ulcers at the terminal ileum and scars on the cecum. In spite of medical management with the diagnosis of Crohn's disease, she continuecl to rebleed and required fistuloplasty and ileal resection. In the surgical specimen was discovered multiple exposed small vessels and diffuse blood oozing at terminal ileum. After surgery, there were no more bleeding episodes and she recovered with the aid treatment of sulfasalazine and prednisolone.

      • KCI등재

        그룹운동 유형이 중년여성의 신체조성과 요부관련근력에 미치는 영향

        최욱철(Choi, Wook-Chul),전병환(Jeon, Byeong-Whan) 한국체육과학회 2014 한국체육과학회지 Vol.23 No.1

        The purpose of this study is to compare changes in the body composition and muscular strength of the lumbar region of middle-age women through 12 weeks of group exercises. Middle-aged Korean women (n=40) were divided into four groups (body pumping group(n=lO), Swiss ball group(n=10), aerobic dance group(n=lO), control group(n=lO)), and carried out 6O-minute of group exercise for 4 days a week for 12 weeks. To compare the changes in body composition and muscular strength of the lumbar region of dependent variables, paired samples t-test was carried out to test for difference before and after. To test the effect between groups, Analysis of Covariate (ANCOVA) was carried out. The result for changes in body composition, weight, body fat amount, visceral fat area, and abdominal circumference were decreased significantly, and the mineral mass, muscle mass in the lower limbs, and protein amount were significantly increased through 12 week-of body pumping exercise. In the Swiss ball group, the weight, body fat amount, and abdominal circumference decreased significantly. In the aerobic dance group, the weight, body fat amount, protein amount, visceral fat area, and abdominal circumference showed decrease statistically. For changes in the lumbar region, there was no significant change of abdominal muscular strength and back strength in the body pumping group and aerobic dance group. In the Swiss ball group, both abdominal and back strength increased significantly. Collectively, it is suggested to select those three kinds of group exercise for improving body composition, and Body Pump composed of complex exercises which are aerobic and anaerobic had a positive effect on muscle quantity of lower limbs, mineral and reduction of fat.

      • KCI등재

        DTN에서 노드 간 연결 가능성과 마스킹 연산을 이용한 중계노드 선정 기법

        정래진,전일규,우병훈,구남경,이강환,Jeong, Rae-jin,Jeon, Il-Kyu,Woo, Byeong-hun,Koo, Nam-kyoung,Lee, Kang-whan 한국정보통신학회 2016 한국정보통신학회논문지 Vol.20 No.5

        This paper propose an improving relay node selection method for node-to-node connectivity. This concern with the mobility and analysis of deployed for masking operation using highest connectivity node. The major of Delay Tolerant Network (DTN) routing protocols make use of simple forwarding approach to transmit the message depend on the node's mobility. In this cases, the selection of the irrelevant mobile node induced the delay and packet delivery loss caused by limiting buffer size and computational power of node. Also the proposed algorithm provides the node connectivity considering the mobility and direction select the highest connectivity node from neighbor node using masking operation. From the simulation results, the proposed algorithm compared the packet delivery ratio with PROPHET and Epidemic. The proposed Enhanced Prediction-based Context-awareness Matrix(EPCM) algorithm shows an advantage packet delivery ratio even with selecting relay node according to mobility and direction. 본 논문에서는 이동 속성 정보를 활용하여 이동 노드간의 연결 가능성을 분석하고 마스킹 기법을 이용하여 이웃한 이동노드 중 목적 노드와 연결 가능성이 가장 높은 이동노드를 중계노드로 선정하는 EPCM(Enhanced Prediction-based Context-awareness Matrix)을 제안한다. 기존 Delay Tolerant Network (DTN)의 전송방식은 노드의 단순 이동성에 의존하여 목적노드로 메시지를 전송하게 된다. 이러한 경우 목적노드와의 연결성이 낮은 이동노드를 중계노드로 선정하게 되면 이동노드의 메시지 저장 및 처리 능력 제한으로 인하여 전송 지연 또는 패킷 손실의 원인이 된다. 본 논문의 제안된 알고리즘에서는 이동노드의 속도와 방향 속성 정보를 고려하여 목적노드와의 연결성을 계산하고 마스킹 연산을 활용하여 가장 높은 연결 가능성을 가지고 있는 중계노드를 선정하여 목적 노드까지 메시지를 전달하게 된다. 모의실험에서 Epidemic 및 PROPHET 알고리즘과 제안하는 알고리즘의 패킷 전송률을 비교한 결과 제안하는 알고리즘이 노드의 이동 속성을 고려한 연결성으로 보다 높은 패킷 전송률을 보여주었다.

      • KCI등재

        사백산(瀉白散)이 Compound 48/80에 의하여 유도(誘導)된 Anaphylatic shock와 피하반응(皮下反應)에 미치는 영향(影響)

        김민호,한상환,전병득,Kim, Min-Ho,Han, Sang-Whan,Jeon, Byeong-Deuk 대한한방내과학회 1990 大韓韓方內科學會誌 Vol.11 No.2

        Sabaiksan has been prescribed to treat various allergic diseases in herbal medicine which were induced by various vasoactive amine released from the mast cells. The constituents of Sabaiksan are Mori Cortex Radices(MCR), Lycii Cortex Radicis(LCR) and Glycyrrhizae Radix(GR). Recently, simple models of compound 48/80 induced anaphylactic shock and cutaneous reaction in vivo were developed to test various agents employed in the field of allergy and toxicology research. The purpose of this study is to evaluate the effects of Sabaiksan on compound 48/80 induced anaphylactic stock, cutaneous reaction and mesenteric mast cell degranulation rate in ICR mice, and on compound 48/80 induced peritoneal mast cell degranulation and histamine release in vitro. Groups of ICR mice were intraperitoneally pretreated with $100{\mu}{\ell}$ of saline, $MCR(2g/m{\ell}),\;LCR(2g/m{\ell}),\;GR(g/m{\ell})$ or Sabaiksan itself(MCR+LCR+GR) at 24, 12 and 1 hour before compound 48/80 solution ($10{\mu}{\ell}/gm$ B. W) were peritoneally given into them, and then mortality within 72 hours after the compound 48/80 injection, and mesenteric mast cell degranulation rate at 15 minutes after compound 48/80 injection were calculated. In vitro experiment, $400{\mu}{\ell}$ of rat peritoneal mast cell suspension$(10^6cell/m{\ell})$ were pretreated with $50{\mu}{\ell}$ of saline, $MCR(2g/m{\ell}),\;LCR(2g/m{\ell}),\;GR(g/m{\ell})$ or Sabaiksan itself at room temperature for 30 minutes, and then $50{\mu}{\ell}$ of compound 48/80 solution $(100{\mu}g/m{\ell})$ were added into it. 30 minutes after the addition of compound 48/80 solution, histamine release assay in the supernatant of peritoneal mast cell suspension were performed employing radioisotope enzymatic assay and morphologic changes of mast cells in each regular time point were photographed. Compared with controls, compound 48/80 induced anaphylactic shock was significantly inhibited by MCR and GR pretreatment into the ICR mice. Significant inhibition of compound 48/80 induced cutaneous reaction, mesenteric mast cell degranulation rate in vivo and histamine release from the rat peritoneal mast cells in vitro was observed only in MCR pretreated group. From the above results, it is suggested that MCR component of Sabaiksan may playa key role to suppress mast cell function since it has been applied to various allergic diseases.

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