Effect of Ionizing Radiation on Rat Tissue: Proteomic and Biochemical Analysis

Park*, Eui‐,Chul,Yoon, Jong‐,Bok,Seong*, Jin‐,Sil,Choi, Kyoung‐,Soo,Kong, Eung‐,Sik,Kim, Yun‐,Jeong,Park, Young‐,Mee,Park, Eun‐,Mi Taylor Francis 2006 Preparative biochemistry & biotechnology Vol.36 No.1

<P>Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes in the oxidative stress markers upon irradiation. We characterized the changes in the proteome profile in rat liver after administering irradiation, and the affected proteins were identified by MALDI-TOF-MS and ESI-MS/MS. The identified proteins represent diverse sets of proteins participating in the cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization of a global proteome change caused by ionizing radiation to unravel the molecular mechanisms involved in the cellular responses to ionizing radiation.</P>

Automatic extension of Gene Ontology with flexible identification of candidate terms

Lee, Jin-Bok,Kim, Jung-jae,Park, Jong C. Oxford University Press 2006 Bioinformatics Vol.22 No.6

<P><B>Motivation:</B> Gene Ontology (GO) has been manually developed to provide a controlled vocabulary for gene product attributes. It continues to evolve with new concepts that are compiled mostly from existing concepts in a compositional way. If we consider the relatively slow growth rate of GO in the face of the fast accumulation of the biological data, it is much desirable to provide an automatic means for predicting new concepts from the existing ones.</P><P><B>Results:</B> We present a novel method that predicts more detailed concepts by utilizing syntactic relations among the existing concepts. We propose a validation measure for the automatically predicted concepts by matching the concepts to biomedical articles. We also suggest how to find a suitable direction for the extension of a constantly growing ontology such as GO.</P><P><B>Availability:</B> http://autogo.biopathway.org</P><P><B>Contact:</B> park@nlp.kaist.ac.kr</P><P><B>Supplementary information:</B> Supplementary materials are available at <I>Bioinformatics</I> online.</P>

宜寧 全義李氏 出土服飾의 세척방법에 관한 연구

박윤미,황은경,정복남 服飾文化學會 2003 服飾文化硏究 Vol.11 No.6

The purpose of study is to find out a suitable cleaning method for excavated textiles of Jeon-ui Lee(1570~1647). The tektites were excavated from her tomb in 1997, and her descendents put them in a box without any treatment and kept them in the warehouse since then. We used two kinds of silk as samples, non-dyed and dyed textile. The experiment was performed by 8 kinds of wet cleaning and dry cleaning methods, an ultrasonic cleaner was used in the wet cleaning, decane and perchloroethylene were used as solvents in the dry cleaning. The use of the ultrasonic cleaner in the wet cleaning method did not show any damage to the fibers of the textiles and it not only cleaned well but also was safe for the fugitive dyes. It resulted in more effective cleaning when the detergent was used together. Therefore, it is effective to use the ultrasonic cleaning on the delicate historical textiles and helpful to the operator's safety and environment.

청소년, 성인, 노인의 수면의 질과 수면 방해 요인 비교

박현숙,김경덕,김경혜,정복례 대한간호학회정신간호학회 2000 정신간호학회지 Vol.9 No.4

The purpose of this study is to search for sleep quality and factors which are influenced on sleep among adolescents, adults and elderly Subjects were 108 adolescents, 85 adults and 114 elderly who live around Taegu city. The data were collected from August 10, 1998 to January 20, 1999. A self-rating questionnaire was used to collect data. Data were analysed in frequency, percentage, X^2 -test, means, standard deviation, t-test, ANOVA, and Scheffe test by SAS computer programme. The results of this study were as follows : The mean score on quality of sleep was 4.57 in adult, 5.79 in adolescents, and 6.71 in elderly. There were statistically significant in quality of sleep among three groups. The mean score of quality of sleep in adults was the highest compared to others. The subjective quality of sleep in elderly was poorer than adults. Quality of sleep in elderly was characterized by prolonged sleep latency, reduced sleep duration, lowered habitual sleep efficiency. Adolescents had the highest level of daytime dysfunction among the three groups. Factors which were influenced on sleep in daily life were investigated. Adolescents were disturbed by 'nocturia(4.6%)', 'feeling too cold(4.6%)', and 'dreams(4.6%)'. Adults were disturbed by 'nocturia(7.1%)', 'other reasons(5.9%)', and 'cough and loud snoring(2.4%)'. And the elderly were disturbed by 'nocturia(75.5%)', 'other reasons(7.9%)', 'shortness of breath(4.4%)', and 'cough and loud snoring(4.4%). Nocturia was the common disturbing factor which was influenced on sleep in the elderly.

고혈압 환자의 트레이닝 효과

박복현 ; 차영수 김천대학교 1998 김천대학교 논문집 Vol.19 No.-

Training is very important for health, physical fitness and prevention of various kinds of disease. Recently, hypokinesis from automation, excessive caloric intake and stresses from personal relations increase and systematic physical exercise are keenly felt. In hypertensive, static or anaerobic exercise are apt to increase blood pressure too much, so moderate or light whole body exercise which intensity can be easily controlled are encouraged. Proper intensity for hypertensive are thought to be within the range of 60% of maximal oxygen consumption (HP 120-135 beats/min). ​

최근 미국의 전자상거래 관련 입법 연구

박복재 여수대학교 2002 論文集 Vol.17 No.-

In this article, I have analyzed the current situation and problems of the U.S. legislations for Electronic Commerce in order to obtain some lessons for the Korean policy for the future legislation. Korea is far behind in this area of law, whereas the United States has unique problems in both procedural and substantive laws. In the former, they have problems of preemption between the federal and state laws, which are peculiar to their federal systems and with which Korea has nothing to do. In the latter, they have conflicts of interest between the Software Makers and Consumers and presently a fierce battle is being waged concerning the Uniform Computer Information Transaction Act. In this regards, Korea will soon face a problem to protect our consumers' interest against the one sided licensing arrangements of the U.S. Software Makers. Korea should wait for the version of UCITA or a U.S. federal legislation which reflects a balanced interest of Software Makers and Consumers.

휨과 축압을 받는 R.C. 柱 矩形 斷面에 對한 韓國과 他國 規準과의 比較 硏究

朴福萬 명지대학교 1979 明大論文集 Vol.12 No.-

It’s required to Compare the economic Reinforced Concrete Column Sections calc-ulated by our Korean stardard with other countries’ under the Combined Loads (axial Loads aud bending Moments). And so, by the same Conditions (Loads and Design strength of materials), we investigated the reinforcement ratio of column Sections as low. 1. When we increase the axial Loads Under the same bending Moments, the ratio of Reinforcement Calculated by A.C.I. Code is the least one among three codes at the Region Ⅱ (Compression Controls). 2. By decreasing the axial Loads Under the Same bending Moments, the ratios by the Korean and Japanese standards show the decreasing phenomina, but the ratio by A.C.I Code increasing one at the Region Ⅲ (tension Controls). And so, there are uneconomical column Sections Under the low axial Loads and large Bending Moments by A.C.I Code. 3. Increasing the bending Moments Under the Same axial Loads at Region Ⅱ, the ratio is the-least one by A.C.I Code, the second one by Korean standard, and the third by Japanese standard. 4. At the Region I, the ratio is the least one by the Korean standard, the second by the Japanese, and the third by A.C.I Code.

보건관리 대행사업 이후 작업환경 수준의 변화

박복현,김화성,이용진,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

This study was performed to evaluate the threshold limit values(TLVs) exceeding rates and periodical changes based on the results from work environmental measurement for 40 factories applied health service program, located in Cheonnan area, from 1995 to 1997. The obtained results were as follows; 1. The hazaed frequency in environmental monitoring were noise(865, 34.4%), illumination(804, 31.9%), dust(205, 8.1%), organic solvent(371, 14.7%), lead(114, 4.5%), and specific chemicals(31, 1.2%), heavy metal(127, 5.0%) in order. 2. The order of TLVs exceeding rate of hazardous agents by type of industries were cement-related manufacture(42.3%), fiber industry(40.0%), food stuff industry(24.3%), metal work industry(21.8%), electronics manufacture (9.9%), other industries(10.2%), chemical industry(7.9%). 3. The mean exceeding rates of hazard by type of industry were 29.5% in noise, 27.3% in dust, 25.8% in specific chemicals, 10.2% in solvent and 7.9% in lead, but none in heavy metal. 4. The average of standardized values of noise divided by TLV were decreased in food stuff industries and chemical industries, but not changed in fiber and cement-related industries. While, the average of standardized values of organic solvents divided by TLVs were decreased in electronic manufacturing industries and other industries.

1.88 A GeV ^56Fe 이온에 의한 원자핵 건판내에서의 발생각에 대한 연구

박복남,최승평,장차익,김동호 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

LBL 667H 실험의 일환으로써 1.88A GeV ^56Fe이온이 원자핵 전판내에서 일으킨 핵반응을 비적스캔닝(along-the-track-scanning) 법으로 총 473개를 발견하였다. 그중 302개에 대한 방출각을 실험데이타로 삼아 ^56Fe 핵과 원자핵건판들과의 충돌에서 얻어진 다중도 분포의 여러파라미더와 이차파쇄핵의 각분포를 측정하여 6.2∼400 GeV 양성자-원자핵 상호작용과 비교검토 하였으며 알파입자에 대한 분포회귀함수는 β_T^-1??e^(r-nb)이고 β_T^-1=(e^(r_p-nb)) 임을 나타냈다. The results of multiple production produced by 1.88 A GeV ^56Fe ions in nuclear emulsion have been studied. Using by the along-the-track scanning method, We found 473 inelastic events and analysed 302 events. Angular distribution of secondary particles and several parameters of multiplicity distribution at the collisions of ^56Fe ions with emulsion nuclei are measured. And data are compared with those of 6.2-400 GeV protons with nuclei in nuclear emulsion. Regression function of alpha particles is well fitted by use of β_T^-1=exp(r-n_b).

「ケンチャナヨ」の機能の諸相

朴福德 中央大學校 日本硏究所 2004 日本 硏究 Vol.0 No.19