[남자1부 단체전 우승] 용인대학교 / 최민선

최민선 대한검도학회 2019 대학검도보 Vol.- No.35

실속링이 대형축류팬의 실속방지에 미치는 영향에 관한 연구

최민선,조대환 木浦海洋大學校 2002 論文集 Vol.10 No.1

Axial flow fan under certain condition may stall. The rise in pressure across the impeller blade of an axial flow fan depends on the angle of attack. At a low back pressure, the air volume will be large and the angle of attack is small. The gradual increase of the back pressure approached stall zone which is not stationary but travels blade to blade passage. The resulting problems along with the severe dynamical loading of structure has demanded for research theoretically and experimentally in understanding and predicting the conditions that cause stall. In this study, methods for avoidance of stall is introduced in which stall ring is used and the stall detector in the axial flow fans has been designed to detect stalling condition with a manometer or differential pressure switch by electric mechanism.

Body image and depression in girls with idiopathic precocious puberty treated with gonadotropin-releasing hormone analogue

최민선,Eun-Young Kim 대한소아내분비학회 2016 Annals of Pediatirc Endocrinology & Metabolism Vol.21 No.3

Purpose: Precocious puberty (PP) is associated with psychological and behavioral problems. This study aimed to evaluate the perception of body image and depression in girls with PP receiving gonadotropin-releasing hormone (GnRH) analogue therapy. Methods: From March to August 2013, 82 girls with PP receiving GnRH analogue therapy were enrolled. Height, weight, body mass index, and stages of pubertal development were assessed. Participants completed a series of questionnaires on their body image perception and pubertal self-assessment. The depression score was calculated using the Korean Kovacs’ Children’s Depression Inventory. Results: The patients perceived their body to be more obese than the controls did. The mean depression score did not differ between the patients and controls. The mean depression scores according to Tanner stages (1: prepubertal, 2: early pubertal, and 3–5: mid to late pubertal stage) by self-assessment were 5.2±3.6, 6.8±4.9, and 11.4±10.1 (P<0.05), respectively. The perception of overall body build and figure (%) and the mean depression scores in patients were: dissatisfied (25.6%, 9.7±7.8) and satisfied (74.4%, 5.5±3.4) (P<0.05). In multiple linear regression analysis, self-T3 (Tanner stage 3–5 by self-awareness) and dissatisfaction about overall body build and figure were found to significantly affect the depression score(P<0.05). Conclusion: The perception of pubertal status and satisfaction about height or weight are unrelated to objective physical findings. Patients with PP are prone to distorted perception about their body image and breast development. Such incorrect body image seems to contribute to depression score.

Expression of hpa1 Gene Encoding a Bacterial Harpin Protein in Xanthomonas oryzae pv. oryzae Enhances Disease Resistance to Both Fungal and Bacterial Pathogens in Rice and Arabidopsis

최민선,허성기,백남천,고희종,Jung-Sook Lee,오창식 한국식물병리학회 2012 Plant Pathology Journal Vol.28 No.4

Xanthomonas oryzae pv. oryzae causing bacterial leaf blight disease in rice produces and secretes Hpa1 protein that belongs to harpin protein family. Previously it was reported that Hpa1 induced defense responses when it was produced in tobacco. In this study, we expressed hpa1 gene in rice and Arabidopsis to examine the effects of Hpa1 expression on disease resistance to both fungal and bacterial pathogens. Expression of hpa1 gene in rice enhanced disease resistance to both X. oryzae pv. oryzae and Magnaporthe grisea. Interestingly,individual transgenic rice plants could be divided into four groups, depending on responses to both pathogens. hpa1 expression in Arabidopsis also enhanced disease resistance to both Botrytis cineria and Xanthomonas campestris pv. campestris. To examine genes that are upregulated in the transgenic rice plants after inoculation with X. oryzae pv. oryzae, known defense-related genes were assessed, and also microarray analysis with the Rice 5 K DNA chip was performed. Interestingly, expression of OsACS1 gene, which was found as the gene that showed the highest induction, was induced earlier and stronger than that in the wild type plant. These results indicate that hpa1 expression in the diverse plant species, including monocot and dicot, can enhance disease resistance to both fungal and bacterial plant pathogens.

Neonatal Seizures with Diffuse Cerebral White Matter Lesions on Magnetic Resonance Imaging Associated with Rotavirus Infection: A Report of Three Cases

최민선,Sang-KeePark,이재희 대한신생아학회 2018 Neonatal medicine Vol.25 No.2

Rotavirus is the major cause of gastroenteritis in children under the age of 5. Rotavirus infection may lead to several neurological complications as meningitis, encephalitis, convulsion, encephalopathy, hemorrhagic shock, central pontine myelinolysis, Guillain- Barre syndrome, and Reye’s syndrome. Further, some reports have described diffuse cerebral white matter lesions on diffusion-weighted magnetic resonance imaging (MRI) in neonates with rotavirus induced seizures. Here, we report on three neonates with rotavirus induced seizures with cerebral white matter abnormalities on MRI.

Association of Urinary N-Acetyl-β-D-Glucosaminidase with Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Mellitus without Nephropathy

최민선,전지은,박성운,유지희,안지연,김규리,진상만,허규연,이문규,김재현 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.3

Background: Cardiovascular autonomic neuropathy (CAN) is a common microvascular complication of diabetes and related to albuminuria in diabetic nephropathy (DN). Urinary N-acetyl-β-D-glucosaminidase (uNAG) is a renal tubular injury marker which has been reported as an early marker of DN even in patients with normoalbuminuria. This study evaluated whether uNAG is associated with the presence and severity of CAN in patients with type 1 diabetes mellitus (T1DM) without nephropathy. Methods: This cross-sectional study comprised 247 subjects with T1DM without chronic kidney disease and albuminuria who had results for both uNAG and autonomic function tests within 3 months. The presence of CAN was assessed by age-dependent reference values for four autonomic function tests. Total CAN score was assessed as the sum of the partial points of five cardiovascular reflex tests and was used to estimate the severity of CAN. The correlations between uNAG and heart rate variability (HRV) parameters were analyzed. Results: The association between log-uNAG and presence of CAN was significant in a multivariate logistic regression model (adjusted odds ratio, 2.39; 95% confidence interval [CI], 1.08 to 5.28; P=0.031). Total CAN score was positively associated with loguNAG (β=0.261, P=0.026) in the multivariate linear regression model. Log-uNAG was inversely correlated with frequency-domain and time-domain indices of HRV. Conclusion: This study verified the association of uNAG with presence and severity of CAN and changes in HRV in T1DM patients without nephropathy. The potential role of uNAG should be further assessed for high-risk patients for CAN in T1DM patients without nephropathy.

시간해상도 PIV를 이용한 델타형 날개에서의 와류 유동특성에 관한 연구

최민선,이현,이영호,Choi, Min-Seon,Lee, Hyun,Lee, Young-Ho 한국마린엔지니어링학회 2004 한국마린엔지니어링학회지 Vol.28 No.3

The dominant effect of the interaction between vortices, generated by the addition of the Leading Edge Extension(LEX) in front of the wing, was well observed in this experiment. In this study, systematic approach by PIV experimental method within a circulating water channel was adopted to study the fundamental characteristics of induced vertex generation, development and its breakdown appearing on a delta wing model with or without LEX in terms of four angles of attack($15^{\circ}$, $20^{\circ}$, $25^{\circ}$, $30^{\circ}$) and six measuring sections(30%, 40%, 50%, 60%, 70%, 80%) of chord length. Distributions of time-averaged velocity vectors and vortices over the delta wing model were compared along the chord length direction. High-speed CCD camera which made it possible to acquire serial images is able to get the detailed information about the flow characteristics occurred on the delta wing. Especially quantitative comparison of the maximum vorticity featuring the induced pressure distribution were also conducted to clarity the significance of the LEX existence.

원호익을 갖는 원심펌프 임펠러의 성능에 관한 수치해석

최민선 木浦海洋大學校 1994 論文集 Vol.2 No.1

A centrifugal pump may be considered to be composed of three parts ; a stationary inlet device, a rotating component of impeller, and a recuperating device. The fluid motions in a centrifugal pump are complex. The velocity vectors are not parallel to the walls of the fluid passages, and appreciable secondary motions occur near the impeller discharge and in the diffusing. The flows in these three parts will be interdependent and a correct flow analysis should take into account this interdependence. however, a satisfactory theory that takes into account the combined effect of all these three components on a real fluid stream flowing through the pump is not yet available. For this reason the problem is usually simplified as far as possible, retaining only the essentials. This study limited on the impeller blade design with circular are blade and its related performance analysis. The designed impeller will be described on the screen by graphic of fortran languge. In the following, flow fields in a centrifugal impeller of circular are blades with a sharp leading edge are analysed by adopting a 2nd order accuracy vortex panel method with the following assumption ; a) The flow field is assumed to be two dimensional, inviscid, incompressible, irrotational, except singular points and steady on the rotating coordinate system. b) The effect of volute easing, inlet turn and prerotation is not considered here. c) The inlet velocity along the breadth direction is also assumed to be constant in magnitude and direction. d) Dimensionless flow rate coefficient at maximum efficiency is 0.216 (Q=0.256㎥/min, r²=100㎜, b₂=15㎜, speed=200rpm) The velocity field along the circular arc blade surfaces are examined for various flow rates, blade numbers. This study shows that theoretical head can be calculated without difficulty using vortex panel method.

나선형블레이드 임펠러의 성능특성에 관한 연구

최민선 木浦海洋大學校 1993 論文集 Vol.1 No.1

This study evaluates the performance characteristics of logarithmic blade impeller, which is based on the vortex panel method. The present method is characterized by distributing infinitesimal consecutive panels of linearly varing vortex strength around a blade configuration and computing numerically vorticity strength satisfying boundary condition at control points and Kutta condition at trailing edge. The calculating results are presented velocity and pressure distribution for a 2-D centrifugal pump impeller of logarithmic blade.

Essential Oils from the Medicinal Herbs Upregulate Dopamine Transporter in Rat Pheochromocytoma Cells

최민선,최방섭,김상헌,Sok Cheon Pak,장철호,진영원,김영미,김동일,전송희,구병수 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.10

The dopamine transporter (DAT) protein, a component of the dopamine system, undergoes adaptive neurobiological changes from drug abuse. Prevention of relapse and reduction of withdrawal symptoms are still the major limitations in the current pharmacological treatments of drug addiction. The present study aimed to investigate the effects of essential oils extracted from Elsholtzia ciliata, Shinchim, Angelicae gigantis Radix, and Eugenia caryophyllata, well-known traditional Korean medicines for addiction, on the modulation of dopamine system in amphetamine-treated cells and to explore the possible mechanism underlying its therapeutic effect. The potential cytotoxic effect of essential oils was evaluated in PC12 rat pheochromocytoma cells using cell viability assays. Quantification of DAT, p-CREB, p-MAPK, and p-Akt was done by immunoblotting. DAT was significantly reduced in cells treated with 50 lM of amphetamine in a time-dependent manner. No significant toxicity of essential oils from Elsholtzia ciliata and Shinchim was observed at doses of 10, 25, and 50 μg/mL. However, essential oils from A. gigantis Radix at a dose of 100 μg/mL and E. caryophyllata at doses of 50 and 100 μg/mL showed cytotoxicity. Treatment with GBR 12909, a highly selective DAT inhibitor, significantly increased DAT expression compared with that of amphetamine only by enhancing phosphorylation of mitogen-activated protein kinases (MAPK) and Akt. In addition, essential oils effectively induced hyperphosphorylation of cyclic-AMP response elementbinding protein (CREB), MAPK, and Akt, which resulted in DAT upregulation. Our study implies that the essential oils may rehabilitate brain dopamine function through increased DAT availability in abstinent former drug users.