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진병철,문희진,김상욱 대한소화기학회 2022 대한소화기학회지 Vol.80 No.2
Latent tuberculosis (TB) infections (LTBI) impose clinical challenges in terms of the diagnosis and treatment of inflammatory bowel disease (IBD), especially in TB-endemic areas. While steroids and biologics have become increasingly useful in the treatment of patients with moderate-to-severe IBD, the risk of reactivation or developing TB is increased due to their potent immunosuppressive effects. Tumor necrosis factor-alpha inhibition may result in the activation of a latent TB infection, and most cases manifest as more severe forms of disseminated TB. All potential users of immunosuppressive therapy should be screened for LTBI, and appropriate measures for the management of latent and active TB should be undertaken with immediate initiation of anti-TB treatment. Biologics should be withheld during TB treatment, and the proper timing for the resumption of IBD therapy during or after TB treatment should be individualized. This review summarizes the latest knowledge on the risk assessment, detection, and management of latent and active TB infections in patients with IBD.
Byun,Sang Kil,Lee,Hee Keung,JIn,Byung Rho,Oh Meung Chull,Kim,Tae Joo,Kim,Young Jun 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1
영남대학교 의과대학 부속병원 치과 ·구강외과에 상 ·하악 전돌을 가진 환자가 안모 추형으로 인한 심미적 장애와 상악 전치부 치간이개 및 하악전치부 치열부정을 주소로 내원하였다. 안면치조기형에 대한 육안적평가, 방사선학적검사, 두부계측사진분석 및 진단 모형분석 등 다각적인 분석 결과 상 ·하악 치조 전돌증으로 진단을 내렸으며, 내원 당시 본 환자는 전반적으로 치주병학적 문제점을 가지고 있었고 개인적으로 군입대라는 특수상황하에 있었기 때문에 치주조직에 대한 손상을 최소로 하면서 치료기간을 최대한 단축시킬 수 있는 치료계획을 세웠다. 상하악 전치부에 대한 술전교정 치료 후 상악골은 전방부분절 골절단술로 후방으로 이동시키고 하악골은 전방부분 치근단 하방 골절단술로 후하방으로 이동시키므로서 상하악 전돌증에 대한 악교정 외과적 처치를 하여 좋은 결과를 얻었기에 이에 보고하는 바이다. The authors treated a case of bimaxillary dentoalveolar protrusion corrected by anterior segmental osteotomies: As presurgical treatment & process, closing of the upper anterior spacing with fixed appliances was worked out, cephalometric prediction & model surgery was done, and fabrication of intra-arch acrylic resin splints were made. It was not necessary to make an intermaxillary fixation with wire after surgery. Only intramaxillary fixation of anterior retracted mobile segment with resin pkate was required for 8 weeks. After surgical treatment, leveling of the upper and lower arch with rectangular arch wire were accomplished as the intrusion of anterior teeth proceeded. We will continue to improve the class Ⅱ molar relationship by using class Ⅱ elastics and have a good occlusion through the orthodontic treatment.