FEF_(25-75%)를 이용한 소아 천식의 중증도 평가

정선윤,이은실,이영환,문한구 대한소아과학회 2001 小兒科 Vol.44 No.8

컨벤션센터의 ESG 평가지표 표준화 방안 연구

정선윤,이세준,김이태 한국호텔외식관광경영학회 2023 호텔경영학연구 Vol.32 No.4

As a follow-up study of 「Using ESG Management for Convention Centers: Focusing on BEXCO」, this study aims to present requirements and suggestions for ESG standards that can be used by convention centers in a rapidly growing ESG rating environment. Because of the rapid growth of public concerns about ESG management among corporations, ESG rating practices and related industries have developed dramatically. More than six hundred ESG rating organizations are now conducting their ESG rating and releasing the results. The ESG rating results diverge among these organizations, so effective ESG rating standards are necessary. As a precondition for this, this paper classifies ESG rating-related organizations by characteristics. The categorization works as a good guide in searching and arranging information for ESG rating. As a second condition, this paper presents the development stage of ESG rating: the early and beginning stage. Because ESG rating is a young field, the Korean Ministry of Trade, Industry and Energy has announced the K-ESG guideline, and KCGS(Korea Institute of Corporate Governance and Sustainability) has updated its ESG Codes of Best Practices. The ISO/IEC international standards can perform as ESG rating standards by their nature. This paper presents ISO/IEC standards that can be used as ESG rating standards for convention centers. The ESG evaluating criteria presented in the previous study expanded by including and considering the K-ESG guideline, ESG Codes of Best Practices, ISO/IEC international standards, and the current management practice of the top 4 convention centers by size in Korea. This paper presents ESG rating standards that provide dependable criteria for stakeholders, promote efficient ESG management for convention centers, and help convention centers and rating organizations focus on the essence of sustainable management. These standards can perform as a guideline for related parties to refer to a time when ESG rating for convention centers is evolving and entering its maturity stage. 본 연구는 ‘컨벤션센터의 ESG 운영방안 연구: BEXCO를 중심으로’의 후속 연구로 급속하게 진화하고 있는 ESG 평가 환경에서 컨벤션센터가 활용할 수 있는 ESG 평가지표의 표준을 제시하고자 하였다. ESG 평가에 대한 시대적 요구가 증대하고 있는 가운데, 전세계 ESG 평가기관의 숫자가 600개가 넘고 같은기업이 평가기관에 따라 상이한 평가결과를 받고있는 실정으로 어느 때 보다도 효과적이고 효율적인 평가표준이 필요한 시기이다. ESG 평가지표 표준화를 이해하기 위한 선행조건으로 본 연구는 ESG 평가지표 유관기관을 성격별로 구분하여 제시하고 특징을 설명하였다. 카테고리별 기관의 유형과 특징, 대표적인 기관을이해하면 구분별로 기관의 성격을 이해할 수 있고 이를 통해 ESG 평가에 필요한 정보를 수집하고 정리하고적용하는데 가이드라인으로 활용할 수 있다. 두 번째 선행 조건으로 ESG 평가의 발전단계를 진화론적으로이해했을 때 ESG 평가에 시사하는 바가 있음을 제시하였다. 우리나라의 경우 산업통상자원부에서 K-ESG 가이드라인을 발표하고 개정하고 있으며, 대표적인 ESG 평가기관인 한국기업지배구조원(KCGS)에서도 모범규준을 개정하였다. ESG 평가에 활용할 수 있는 대표적인 국제 표준은 ISO⋅IEC 표준이다. 본 연구에서는 컨벤션센터의 ESG 경영 평가 표준으로 활용할 수 있는 ISO⋅IEC인증을 재분류 하여 제시하였다. 선행연구에서 도출한 컨벤션센터 ESG 평가항목에 산업통상자원부의 K-ESG 가이드라인, 한국기업지배구조원의 모범규준, ISO⋅IEC표준을 적용하여 면적별로 상위 4개 센터의 경영현황에 적용하여 분석하였다. 이를종합하여 이해관계자를 대상으로는 신뢰성을 확보할 수 있고, 컨벤션센터 및 평가업무 수행기관의 입장에서는 경영효율과 지속가능경영이라는 핵심에 충실 할 수 있는 평가표준안에 대해 제언하였다. 본 평가표준안은 컨벤션센터의 ESG 평가가 성숙기 단계로 진입하는 과정에서 관련 이해관계자들이 참고할 수 있는 가이드라인의 역할을 할 수 있을 것이다.

High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity.

정선윤,이막순,신윤진,김종태,김인환,김양하 한국식품영양과학회 2015 Preventive Nutrition and Food Science Vol.20 No.4

Chronic low-grade inflammation is associated with obesity. This study investigated effect of high hydrostatic pressure extract of red ginseng (HRG) on inflammation in rats with high-fat (HF) diet induced obesity. Male, Sprague-Dawley rats (80∼110 g) were randomly divided into two groups, and fed a 45% HF diet (HF) and a 45% HF diet containing 1.5% HRG (HF+HRG) for 14 weeks. At the end of the experiment, the serum leptin level was reduced by the HRG supplementation. The mRNA expression of genes related to adipogenesis including peroxisome proliferator-activated receptor-gamma and adipocyte protein 2 was down-regulated in the white adipose tissue (WAT). The mRNA levels of major inflammatory cytokines such as tumor necrosis factor-α, monocyte chemoattractant protein 1, and interleukin-6 were remarkably down-regulated by the HRG in WAT. These results suggest that HRG might be beneficial in ameliorating the inflammation-associated health complications by suppressing adipogenic and pro-inflammatory gene expression.

Successful Treatment of Postoperative Fistula with Infliximab in a Patient with Crohn’s Disease

정선윤,문정섭,박규주,김유선 대한장연구학회 2014 Intestinal Research Vol.12 No.1

Nearly 80% of patients with Crohn’s disease (CD) require surgical treatment for complications or failure of medical management. We managed a 31-year-old man with CD who presented with a post-operative fistula. The patient had undergone surgery due to multiple strictures and a fistula. However, a new fistula developed that connected to the intraperitoneal abscess. Intravenous antibiotics were started and multiple percutaneous drainage tubes were inserted to treat the abdominal abscess. However, the amount of drainage was consistently high, even one month after the operation. To treat the postoperative fistula, 5 mg/kg of infliximab was started, and the amount of drainage decreased dramatically to less than 10 cc a day. Some studies have reported that infliximab decreases the recurrence of CD after surgery. The effect of infliximab on post-operative fistulas in patients with CD has not been sufficiently studied. Our results indicated that the use of infliximab to treat post-operative fistula should be explored further in future clinical studies.

FEF25-75% 를 이용한 소아 천식의 중증도 평가

정선윤,이은실,이영환,문한구 대한소아청소년과학회 2001 Clinical and Experimental Pediatrics (CEP) Vol.44 No.8

컨벤션센터의 ESG 운영방안 연구: BEXCO를 중심으로

정선윤,이세준,김이태 한국호텔외식관광경영학회 2022 호텔경영학연구 Vol.31 No.3

The ESG(Environmental, Social, and Corporate governance) management is a major concern among industries worldwide. Because of the outbreak and rapid spread of the Covid-19, public concern about envi- ronmental and social issues has increased. Governmental regulations on environmental protection are getting strengthened, and new practices and criteria on environmental investment are being introduced. Many corpo- rations are announcing their policies regarding ESG issues, and stakeholders are actively trying to find ways to encourage companies to be more socially responsible. Convention centers in Korea have common charac- teristics: large facilities, many participants, and economic impact around the region. The top 4 centers meas- ured by size are all corporations and the main shareholders are governmental organizations or alike. They may soon require convention centers to adopt ESG management and publicize non-financial activities. Therefore, it is time to develop certain non-financial criteria evaluating convention center management. In this study, the management practices of BEXCO(Busan Exhibition & Convention Center) are reviewed by the Korean representative ESG evaluating index: KEJI(Korean Economic Justice Institute) Index and KCGS (Korean Corporate Governance Service) Index. The purpose of this case study is to review the current state of ESG management of BEXCO and to propose practical ESG criteria, which can be used for evaluating the non-financial performance of convention centers. Some may question the necessity of such criteria. It is because convention centers are not KOSPI(Korea Composite Stock Market Price Index) listed companies, so ESG evaluation is not mandatory. However, stakeholders like shareholders, center users, and local community members are all observing the responsible actions of convention centers. Therefore, it is time for convention centers to consider how to use ESG management practices to become socially responsible corporations. The result of this study might be used as an ESG evaluating criteria for convention centers, and can be useful for centers to consider ESG criteria for their general management practices. 최근 ESG 경영은 새로운 경영환경의 패러다임으로 모든 사업 분야에서 주목받고 있다. 2020년 코로나 19사태는 환경파괴에 대한 성찰의 계기가 되었다. 특히, 2021년부터 ‘파리기후변화협약체제’가 ‘교 토의정서체제’를 대체하여 모든 국가가 온실가스 배출량의 감축 의무를 부담하게 되어, 기후변화문제를 포함한 환경문제에 대중적 관심이 높아지면서 ESG 경영이 더욱 주목을 받게 되었다. 국내 컨벤션센터는 대규모의 시설을 보유하고 있고, 행사 개최 시 참여자 수가 많고, 입지주변 지역에 미치는 경제적 파급효과 가 크다는 것이 일반적인 특징이다. 면적별로 상위 4개 사를 살펴보면 주식회사의 형태이면서 주주가 정부 이거나 정부 유사기관임을 확인할 수 있다. 대부분 비상장회사이기 때문에 ESG 투자의 직접적 대상이 되지 는 않지만, 주주기관들과 이해관계자들은 컨벤션센터가 ESG 경영과 같은 비재무적 활동을 통해 지속가능한 경영을 강화할 것을 요구할 것으로 예상된다. 따라서 컨벤션센터의 비재무적 경영활동에 대한 현실적인 평가항목 검토가 필요한 시점이다. 본 연구는 부산에 있는 컨벤션센터인 벡스코의 경영사례를 우리나라의 대표적인 ESG 평가지수인 경제정의실천시민연합의 경제정의지수(KEJI Index)와 한국기업지배구조원 (KCGS)의 ESG 평가기준으로 분석한다. 사례연구를 통해 컨벤션센터에 적용할 수 있는 실무적이고 현실성 있는 비재무적 기업평가지표를 제시하고자 한다. 컨벤션센터의 경우, 비상장기업이므로 ESG 투자와 직접적 인 연관이 없다고 생각할 수 있다. 그러나 주주, 센터 이용자, 지역주민들과 같은 이해관계자들은 컨벤션센 터의 책임 있는 경영활동에 대한 관심을 나타내고 있다. 본 연구의 사례 분석 결과를 바탕으로 ESG 평가항 목 설정에 활용할 수 있으며, 각 센터들이 일반 경영활동에서 ESG 요소를 반영하는데도 활용할 수 있다.

Krabbe병 1례

정선윤(Sun Yoon Jung),문한구(Han Ku Moon) 대한소아신경학회 2001 대한소아신경학회지 Vol.9 No.2

저자들은 보챔과 구토, 서서히 진행되는 발달의 지체와 퇴행을 주소로 내원 하였던 11개월된 남아에서 미만성 말초신경병증에 부합되는 소견, 경도의 단백이 증가한 뇌척수액 소견 그리고 뇌 백질 변성의 소견을 보이는 뇌 자기공명영상 소견이 나타나고 백혈구의 galactocerebroside β-galactosidase 활성도의 감소로 퇴행성 뇌질환인 Krabbe병으로 확진한 예를 경험하여 보고하는 바이다. Krabbe disease is an autosomal recessive neurodegenerative disorder that affects both the central and peripheral nerve system due to an enzymatic defect of galactocerebroside β-galactosidase. The patient had typical clinical features of Krabbe disease, with irritability, hypertonicity, failure to thrive, and opisthotonic posturing. A brain MRI demonstrates profound white matter demyelination. The diagnosis of Krabbe disease is suspected on the basis of clinical pictures and confirmed by finding markedly reduced galactocerebroside β-galactosidase activity in leukocyte or cultured fibroblast. Here we present the first reported case of Krabbe disease in Korea confirmed by decreased activity of galactocerebroside β-galactosidase enzyme in leukocyte.

Physicochemical characteristics of Ethiopian Coffea arabica cv. Heirloom coffee extracts with various roasting conditions

김인용,정선윤,김은경,이진욱,김찬양,하정흔,정윤화 한국식품과학회 2021 Food Science and Biotechnology Vol.30 No.2

This study aimed to investigate the physicochemicalcharacteristics of Ethiopian Coffea arabica cv. Heirloom coffee extracts with various roasting conditions. Green coffee beans were roasted at four different conditions(Light-medium, Medium, Moderately dark, and Verydark) and used to extract espresso and drip coffee. Moisturecontent in coffee beans was decreased as the roastingdegree increased. The contents of crude fat and ash werelower in the Light-medium roasted coffee beans than ingreen coffee beans but increased as the roasting degreeincreased. The values of lightness (L*), redness (a*), yellowness(b*), and browning index of coffee extracts weredecreased as the roasting degree increased. Total dissolvedsolids in espresso coffee were increased with increasingroasting degree but decreased in drip coffee. In both theextracts, the contents of reducing sugar, titratable acidity,organic acids, and chlorogenic acid were decreased, butthat of caffeine was increased with the roasting degreeincreased.

로스팅 조건에 따른 엘살바도르산 Coffea arabica cv. Bourbon 커피의 이화학적 특성

김인용,정선윤,김은경,윤혜연,장석암,하정헌,정윤화 한국식품과학회 2020 한국식품과학회지 Vol.52 No.3

The physicochemical characterstics of El Salvadoran Coffea arabica cv. Bourbon coffee extracts under various roasting conditions were investigated. Green beans were roasted under four different conditions (Light-medium, Medium, Moderately dark, and Very dark). The coffee extracts were prepared by using the espresso or drip methods. As the roasting degree increased, the coffee bean moisture content decreased and the ash content increased. The lightness and yellowness of the beans and coffee extracts decreased along with the increasing roasting degree. In the drip coffee, the reducing sugar content decreased and the pH value increased along with the increasing roasting degree. Both in the espresso and drip coffee, total organic acid and chlorogenic acid contents decreased, while the caffeine content increased along with the increasing roasting degree. Therefore, it is suggested that the roasting degree affects the physicochemical characteristics of coffee extracts.

High Hydrostatic Pressure Extract of Ginger Exerts Antistress Effects in Immobilization-Stressed Rats

문소희,이막순,정선윤,강보리,김석영,박선영,손혜연,김종태,조영희,김인환,김영순,김양하 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.9

Stress contributes to physiological changes such as weight loss and hormonal imbalances. The aim of the present study was to investigate antistress effects of high hydrostatic pressure extract of ginger (HPG) in immobilization-stressed rats. Male Sprague-Dawley rats (n = 24) were divided into three groups as follows: control (C), immobilization stress (2 h daily, for 2 weeks) (S), and immobilization stress (2 h daily, for 2 weeks) plus oral administration of HPG (150 mg/kg body weight/day) (S+G). Immobilization stress reduced the body weight gain and thymus weight by 50.2% and 31.3%, respectively, compared to the control group. The levels of serum aspartate transaminase, alanine transaminase, and corticosterone were significantly higher in the stress group, compared to the control group. Moreover, immobilization stress elevated the mRNA levels of tyrosine hydroxylase (Th), dopamine beta-hydroxylase (Dbh), and cytochrome P450 side-chain cleavage (P450scc), which are related to catecholamine and corticosterone synthesis in the adrenal gland. HPG administration also increased the body weight gain and thymus weight by 12.7% and 16.6%, respectively, compared to the stress group. Furthermore, the mRNA levels of Th, Dbh, phenylethanolamine-N-methyltransferase, and P450scc were elevated by the HPG treatment when compared to the stress group. These results suggest that HPG would have antistress effects partially via the reversal of stress-induced physiological changes and suppression of mRNA expression of genes related to corticosterone and catecholamine synthetic enzymes.