집중호우로 인한 한강변 간선도로 침수 피해

이정우,이정은,이동섭,Lee, Jeong-U,Lee, Jeong-Eun,Lee, Dong-Seop 한국수자원학회 2011 물과 미래(한국수자원학회지) Vol.44 No.10

아미설프라이드로 유발된 고프로락틴혈증: 예비 연구

이정우,박영민,이승환,강승걸,이분희,박은진,Lee, Jung-Woo,Park, Young-Min,Lee, Seung-Hwan,Kang, Seung-Gul,Lee, Bun-Hee,Park, Eun-Jin 한국정신신체의학회 2011 정신신체의학 Vol.19 No.1

연구목적: 고프로락틴혈증은 항정신병약물로 인한 흔한 부작용이다. 그럼에도 불구하고 이러한 고프로락틴혈증에 대한 임상가들의 관심은 적은 편이다. 왜냐하면 고프로락틴혈증으로 인한 부작용의 심각성이 널리 알려지지 않았기 때문이다. 특히 아미설프라이드로 인한 고프로락틴혈증에 대한 국내 연구는 전무한 실정이다. 본 연구에서는 한국인에서의 아미설프라이드로 인한 프로락틴 수치의 변화를 알아보고자 한다. 방 법: 2008년 1월부터 2010년 12월까지 일산백병원 신경정신과의 외래와 입원 환자 24명을 대상으로 의무기록을 검토하여 자료를 분석하였다. 이를 통해 아미설프라이드 사용 전후의 프로락틴 수치의 변화를 비교하였다. 또한 아미설프라이드 용량, 투약 기간과 프로락틴 수치 변화율과의 상관관계를 통계적으로 분석하였다. 결 과: 아미설프라이드를 투여한 모든 환자에서 고프로락틴혈증이 발생하였다. 아미설프라이드 투여 후의 프로락틴 수치는 투여 전 보다 유의하게 상승하였다(z=-3.702, p=0.000). 아미설프라이드 용량과 프로락틴 상승의 정도는 유의한 상관관계를 보였으나(r=0.61, p=0.002), 아미설프라이드 투여 기간과 프로락틴 상승의 정도는 유의한 상관관계를 보이지 않았다. 또한 아미설프라이드 용량과 프로락틴 수치 변화율은 유의한 상관관계를 보이지 않았다. 결 론: 아미설프라이드를 포함한 항정신병약물은 프로락틴 수치를 증가시켜 장 단기간의 부작용을 발생시킬 수 있다. 따라서 아미설프라이드를 사용하는 임상의는 프로락틴 수치를 정기적으로 측정하여야 하며 고프로락틴혈증과 관련된 부작용을 평가하여야 한다. Objective: Hyperprolactinemia is common side effect associated with antipsychotics use. Nevertheless, hyperprolactinemia is relatively neglected by clinician. Especially, there is no study related to amisulprideinduced hyperprolactinemia in korea. This study aimed to determine whether amisulpride can be induced hyperprolactinemia in Korean psychiatric patients. Methods: This study methodology consisted of a retrospective review of medical charts and prolactin levels. Serum prolactin levels were measured in 24 Korean patients(12 males and 12 females) with psychosis who were treated over 400mg of amisulpride per day. Results: All patients had hyperprolactinemia. Prolactin levels significantly increased after receiving amisulpride(z=-3.702, p=0.000). The prolactin level was significantly higher in females($156.29{\pm}63.75$ng/mL) than in males($69.04{\pm}39.91$ng/mL) after administering amisulpride(p=0.000). There was a correlation between dosage and prolactin levels(r=0.61, p=0.002). However, there was no correlation between duration of treatment and prolactin levels. Conclusions: Antipsychotics, especially amisulpride can increase serum prolactin levels and may results in short and long term side effects. Routine clinical assessment of initial and additional prolactin level and associated symptoms should be done

신경근전기자극에 의한 척수운동신경원의 흥분성 변화

이정우,김태열,이인학,이준희,Lee, Jeong-Woo,Kim, Tae-Youl,Lee, In-Hak,Lee, Joon-Hee 대한임상전기생리학회 2003 대한임상전기생리학회지 Vol.1 No.1

The purpose of this study was to determine the effect of neuromuscular electrical stimulation(NMES) on the alteration of spinal motor neuron excitability. In this article, I would like to experiment on a standard capacity of clinical electrophysiology, a difference in applying methods and a clinical efficiency of NMES by Nerve conduction velocity. We used normal eight subjects without neuromuscular disease and all subjects participated 3 session, which at least 1 week between session. Participants classified according to each group in Antagonist, Agonist, Antagonist-Agonist by the NMES. The test was measured continuously pre test, post-test, post 20 minute test by EMG including H reflex, F wave, motor nerve conduction velocity(MNCV). The following results were obtained; 1. H-reflex latencies and H/M intervals were significantly increased in agonist and antagonist-agonist group(p<.01). 2. H-reflex amplitudes and H/M ratios were significantly decreased in agonist and antagonist-agonist group(p<.01). In agonist group, H-reflex amplitudes and H/M ratios were more significantly decreased than antagonist group. 3. F-wave latencies were significantly increased in agonist and antagonist-agonist group(p<.01). F/M intervals were significantly increased in antagonist-agonist group(p<.01). F wave conduction velocities were significantly increased in agonist and antagonist-agonist group(p<.01) but F/M ratios were not significant. 4. MNCV were significantly decreased in agonist(p<.01). These results lead us to the conclusion that agonist and Antagonist-agonist was significantly decreased excitability of spinal motor neuron. Conversely, Antagonist does not decreased. Therefore, A further direction of this study will be to provide more evidence that NMES have an effect on excitability of spinal motor neurons in UMN syndrome.

시계열분석을 적용한 저장탄약수명 예측 기법 연구 - 추진장약의 안정제함량 변화를 중심으로 -

이정우,김희보,김영인,홍윤기,Lee, Jung-Woo,Kim, Hee-Bo,Kim, Young-In,Hong, Yoon-Gee 한국국방경영분석학회 2011 한국국방경영분석학회지 Vol.37 No.1

야전에 저장된 탄약의 수명을 예측하는 것은 군의 전투지원 핵심요소로 실무적으로 매우 중요한 의미가 있다. 본 연구는 6년간 수행한 155mm 추진장약(KD541)의 ASRP(Ammunition Stockpile Reliability Program : 저장탄약신뢰성평가) 결과를 기초로 추진장약 추진제의 안정제함량 변화에 따른 시계열분석 (ARIMA 모델) 방법론을 적용 저장탄약수명을 예측하였다. 이번 연구는 기존의 회귀분석 모델을 활용한 연구방법과 다르게 시계열분석을 적용하되 미니 탭 프로그램을 활용하여 시계열분석을 적용 저장탄약수명을 예측하였다. 이러한 분석결과 155mm 추진장약(KD541) 저장수명은 35~43년으로 예측되었다. To predict the shelf-life of ammunition stockpiled in intermediate have practical meaning as a core value of combat support. This research is to Predict the shelf-life of ammunition by applying time series analysis based on report from ASRP of the 155mm, KD541 performed for 6 years. This study applied time series analysis using 'Mini-tab program' to measure the amount of stabilizer as time passes by is different from the other one that uses regression analysis. The average shelf-life of KD541 drawn by time series analysis was 43 years and the lowest shelf-life assessed on the 95% confidence level was 35 years.

$\textrm{SiO}_2$-$\textrm{B}_2\textrm{O}_3$-CaO-$\textrm{P}_2\textrm{O}_5$계에서 조성이 Aerosol Flame Deposition법에 의해 제조된 유리박막의 열처리 온도와 굴절률에 미치는 영향

이정우,정형곤,정석종,이형종,문종하,Lee, Jeong-U,Jeong, Hyeong-Gon,Jeong, Seok-Jong,Lee, Hyeong-Jong,Mun, Jong-Ha 한국재료학회 1999 한국재료학회지 Vol.9 No.5

The effects of the composition on the consolidation temperature and refractive index of the glass thin film fabricated by aerosol flame deposition method in SiO$_2$-B$_2$O$_3$-CaO-P$_2$O\ulcorner system were investigated. When the amount of CaO was constant in SiO$_2$-B$_2$O$_3$-CaO system the consolidation temperature of glass thin film decreased with increasing the amount of B$_2$O$_3$. Also, when the amount of SiO$_2$ and B$_2$O$_3$ was constant the consolidation temperature of glass thin film increased with increasing the amount of CaO. P$_2$O\ulcorner was added to 72.5SiO$_2$-25B$_2$O$_3$-2.5CaO in order to decrease its consolidation temperature. As the amount of P$_2$O\ulcorner increased its consolidation temperature decreased and the refractive index linearly increased from 1.4649 to 1.4684. When the amount of CaO and P$_2$O\ulcorner was constant in SiO$_2$-B$_2$O$_3$-CaO-P$_2$O\ulcorner system the consolidation temperature of glass thin film decreased with increasing the ratio of SiO$_2$/B$_2$O$_3$.

자연공원과 야생조(19)-붉은배새매

이정우,Lee, Jeong-U 한국자연공원협회 1993 한국자연공원 Vol.58 No.-

수중로봇 소프트웨어 시스템의 요구사항을 반영한 ROS 기반의 계층화된 소프트웨어 아키텍처의 설계

이정우,최영호,이종득,윤성조,서진호,Lee, Jung-Woo,Choi, Young-Ho,Lee, Jong-Deuk,Yun, Sung-Jo,Suh, Jin-Ho 대한임베디드공학회 2017 대한임베디드공학회논문지 Vol.12 No.5

Underwater robots operating in constrained underwater environment have requirements for software systems. Firstly, it is necessary to provide reusable common software components for hardware interface of sensors and actuators that are frequently used in underwater robots. Secondly, it is required to support distributed execution environment on multiple embedded controllers. Thirdly, it is need to implement a monitoring system capable of high-speed and large-data transmission for underwater robots operating in an environment where it is difficult to check the robot status. For these requirements, we have designed the layered architecture pattern and applied several design patterns to enhance the reusability and the maintainability of software components, In addition, we overlaid the broker architecture pattern to support distributed execution environments. Finally, we implemented the underwater robot software system using ROS framework based on the software architecture design. In order to evaluate the performance of the implemented software system, we performed an experiment to measure the response time between components and the transmission rate of the monitoring data, and obtained the results satisfying the required performance.

한국의 노동조합이 임금분배에 미치는 영향

이정우,남상섭 ( Joung Woo Lee,Sang Sup Nam ) 한국경제학회 1994 經濟學硏究 Vol.41 No.3

칼럼-지식정보사회와 도서관정책

이정우,Lee, Jeong-U 한국도서관협회 2007 圖協會報 Vol.48 No.2

2-HP-β-시클로덱스트린과 메글루민을 이용한 란소프라졸의 포접화합물 제조 및 평가

이정우,김정수,장혜진,이계원,지웅길,Lee, Jung-Woo,Kim, Jung-Su,Chang, Hye-Jin,Lee, Gye-Won,Jee, Ung-Kil 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.4

To enhance the solubility and stability of lansoprazole (LAN), new proton pump inhibitor, we were prepared various molar ratio of inclusion complex with $2-hydroxypropyl-{\beta}-cyclodextrin$ (HPCD) and organic alkali agent, meglumine (MEG). Inclusion complex formation of LAN with HPCD was investigated by Differential Scanning Calorimetry and X-ray diffractometry. The aqueous solubilities of inclusion complexes, and the stabilities of 1:4 and 1:5 inclusion complexes in aqueous solutions containing different concentrations of MEG were examined. The stability of 1:5 LAN-HPCD inclusion complex containing MEG, which was equaled to amount of LAN, was performed in 0.9% NaCl and 5% dextrose solution. The formation of inclusion complex of LAN with HPCD was $A_L$ type and the molar ratio of complex was 1:1. The stability constant was $41.557\;M^{-1}$. As molar ratio of LAN to HPCD was increased, solubility of inclusion complex was increased. 1:5 LAN-HPCD inclusion complex was more stable than 1:4 LAN-HPCD inclusion complex. And as contained MEG amount in LAN solution was increased, stability of 1:4 and 1:5 LAN-HPCD inclusion complexes was improved. Also stability of 1:5 LAN-HPCD-MEG inclusion complex in 0.9% NaCl solution and 5% dextrose solution was similar to it in water at room temperature, but it was unstable at $40^{\circ}C$.