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      • SCOPUSSCIEKCI등재

        고령군 뇌동맥류 환자의 치료

        박현선,이재환,김진영,신용삼,주진양,허승곤,이규창,Park, Hyeon Seon,Lee, Jae Whan,Kim, Jin Young,Shin, Yong Sam,Joo, Jin Yang,Huh, Seung Kon,Lee, Kyu Chang 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.6

        Objectives : A clinical analysis was performed to provide management strategy and to improve management outcome of elderly patients with intracranial aneurysm. Patients and Methods : We reviewed medical records of 746 consecutive patients with intracranial aneurysm who were admitted from July 1991 to December 1996. They were divided into two age groups : elderly(120 patients aged 65 years or older) and non-elderly(626 patients aged 64 years or younger). We investigated the differences between the two groups in clinical characteristics, management outcome and surgical results. Results : Female(80.0%), internal carotid artery aneurysm(48.9%), poor clinical grade(Hunt and Hess Grade IV, V : 39.8%), postoperative subdural fluid collection(38.2%), and postoperative hydrocephalus(39.7%) were more frequent in the elderly patients. There were no significant differences in the incidence of hypertension, multiple aneurysm, unruptured aneurysm, rebleeding, delayed ischemic neurological deficits, postoperative hemorrhage, and low density on the postoperative brain CT scan. In some cases, surgical clipping of ruptured aneurysm could not be performed due to moribund state or refusal of surgery by the elderly patient's family. Both management outcome and surgical results in elderly aneurysm patients at 3 months after rupture were worse than those of the non-elderly group. The most common reason of unfavorable outcome was poor clinical grade in both groups, while serious medical illness causing unfavorable outcome was more common in the elderly group. Conclusion : Surgical treatment of a ruptured aneurysm should not be avoided in elderly patient solely on the basis of advanced age. If the patients are in good clinical grade, early aneurysm surgery followed by early ambulation should be recommended. Further improvements in outcome may be achieved by thorough knowledge of poor resilience of brain, CSF flow dynamics, and diminished cardiopulmonary reserve in elderly patients with intracranial aneurysm.

      • SCOPUSSCIEKCI등재

        뇌지주막하 출혈 후 뇌혈관 연축에 대한 동맥내 Papaverine 주입의 치료효과

        신준재,이재환,신용삼,허승곤,김동익,이규창,Shin, Jun Jae,Lee, Jae Whan,Shin, Yong Sam,Huh, Seung Kon,Kim, Dong Ik,Lee, Kyu Chang 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.3

        Objective : To clarify the benefits and therapeutic effects of intra-arterial papaverine infusion on the symptomatic cerebral vasospasm, we analyzed the results of treatment in 32 patients retrospectively. Methods : A total of 510 patients underwent surgical clipping or endovascular intra-aneurysmal treatment for ruptured intracranial aneurysm between May, 1996 and June, 1999. The delayed ischemic deficit(DID) was developed in 90 of 510 patients. Of these 90 patients, 32 developed symptomatic vasospasm inspite of using modest "3H therapy". The brain CT scan was taken before the intra-arterial infusion of papaverine. The 32 patients underwent 42 intra-arterial papaverine infusion. The symptomatic vasospasm was divided into three groups : deterioration of mental status(Group 1), appearance of a focal neurologic deficit(Group 2), or both(Group 3). We measured Glasgow Coma Scale(GCS), arterial diameters, and cerebral circulation time(CCT) at the time of pre- and postangioplasty. Results : The number of patients in group 1, 2 and 3 were 26, 7, 9 respectively. Eighteen cases showed improvement of GCS more than 2 scores, 16 more than 1, and 8 showed no change of GCS. Average cerebral circulation time(CCT) was decreased ranging from 0.0%-67.5%, and arterial diameters were increased in 21 cases ranging from 1 to 4 folds. Conclusion : Intra-arterial papaverine infusion seemed to have therapeutic effects on symptomatic vasospasm by improving the neurological signs and increasing the arterial diameter. We suggest that intra-arterial papaverine infusion would be an useful adjunctive therapeutic modality in symptomatic vasospasm.

      • KCI등재

        흉부 통증을 호소한 소아에서의 임상적 고찰 및 검사

        신수아,김용주,이재환,김남수,문수지,Shin, Su A,Kim, Yong Joo,Lee, Jae Whan,Kim, Nam Su,Moon, Soo Ji 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.12

        목 적 : 소아에 있어서 흉부 통증은 재발성 복통과 더불어 소아과 영역에서 흔히 접하게 되는 문제로, 정확한 원인을 규명하기란 쉽지 않으며 다양한 원인에 의해 발현된다. 소아에서의 흉부 통증은 양성적이고 통증의 경과가 양호하며, 원인을 모르는 경우가 많아 이런 환아들에게서 행해지는 검사가 어떠한 의의가 있는지에 대해서도 정보가 그리 많지 않다. 이에 저자들은 소아 흉부 통증 환자의 특징에 대해 알아보고 검사의 유용성에 대해 알아보고자 본 연구를 시행하였다. 방 법 : 한양대학교병원 소아과에 만성적 흉부 통증을 주소로 내원한 환아 33명(남아 15명, 여아 18명)을 대상으로 흉부 통증의 원인 및 시행하였던 검사들에 대한 결과를 후향적으로 분석하였다. 결 과 : 대상 환아의 연령은 10-12세 사이와 4-6세 사이가 각각 11례(33.3%)로 가장 많은 분포를 보였으며 남, 여 성별의 차이는 없었다. 흉부 통증의 원인으로는 특발성이 15례(45.5%), 심혈관계 검사의 이상을 보인 경우 9례(27.3%), 위장관 질환 6례(18.2%), 호흡기 질환 2례(6%), 흉부 좌상 1례(3%) 순이었다. 대상 환아들에서 보인 심혈관계 검사상 이상 소견은 흉부 통증과 직접적 연관이 있다고 하기 어려웠다. 병력 청취 및 진찰을 통해 상부 위장관 질환이 의심되는 6례에서 이에 대한 검사를 시행하였고 모두에서 상부 위장관 질환의 소견이 관찰되었으며 이에 대한 치료 이후 증상의 재발은 관찰되지 않았다. 결 론 : 소아에서의 흉부 통증은 양성적이고 특발성인 경우가 많으나 심혈관 질환이나 위장관 질환 등의 가능성도 생각해야하며 이를 위해 정확한 병력 청취 및 진찰에 근거해 적절한 검사를 시행함으로써 효과적인 진단 및 치료가 가능할 것이다. Purpose : Chest pain in the pediatric population is not rare and mostly benign. Causes of chest pain are diverse, and differential diagnosis is not easy. Chest pain in children is less likely to be cardiac in origin. Furthermore, chest pain in the pediatric population is rarely associated with life-threatening disease. This study was designed to evaluate children with chest pain and the usefulness of several diagnostic examinations. Methods : Between March 2001 and August 2002, 33 patients(15 boys and 18 girls, aged four to 15 years) presented with chronic chest pain. The records of these patients were reviewed. Chest radiography and electrocardiogram were performed in all patients. Cardiologic and gastrointestinal evaluations were carried out when considered necessary. Results : Chest pain was most common in the age group of 10 to 12 years old, and the four to six years old group. The most common diagnostic findings of chest pain were idiopathic(15 cases, 45.5 %), heart disease(9 cases, 27.3%), upper gastrointestinal disease(6 cases, 18.2%), respiratory disease (2 cases, 6%) and trauma(1 case, 3%). In children with abnormal results of cardiologic evaluation, these findings are not major etiologic categories of chest pain. Through history taking and physical examinations, six cases were evaluated concerning gastrointestinal disease and all of them showed gastrointestinal diseases(esophagitis, gastroesophageal reflux disease, nodular gastritis and chronic superficial gastritis). Conclusion : Chest pain is usually benign in children but the possibility of cardiovascular or gastrointestinal disease is considered. Careful history taking, physical examination and proper clinical examinations are usually required to find out the rare life-threatening causes of chest pain.

      • Comparison of Paclitaxel-Versus Sirolimus-Eluting Stents for the Treatment of Acute ST-Elevation Myocardial lnfarction

        김현숙 ( Hyun Sook Kim ),이재환 ( Jae Hwan Lee ),성인환 ( In Whan Seong ),이승환 ( Seung Whan Lee ),이경석 ( Kyoung Suk Rhee ),김원호 ( Won Ho Kim ),고재기 ( Jae Ki Ko ) 전북대학교 의과학연구소 2007 全北醫大論文集 Vol.31 No.1

        Objectives: Paclitaxel-eluting stent (PES) and sirolimus-eluting stent (SES) are more effective than bare-metal stent for reducing restenosis. However, it is not known whether there are differences between PES and SES in terms of safety and efficacy in the setting of ST-elecation myocardial infarction (STEMI). Methods and Results: Acute STEMI patients (n=231) undergoing primary stenting were randomly assigned to PES (n=115) or SES (n=116) treatment. Primary end point was in-segment late loss at 6 months. Secondary end points were 6-month angiographic restenosis and major adverse cardiac events (MACE) at 9 months. At 6 months, in-segment late loss was higher in the PES than the SES group (0.33±0.70 vs. 0.05±0.40mm, respectively, p<0.001). During 9-month follow-up, 14 (6.1%) patients were died (9 in PES, 5 in SES group). Nine-month TLR (7.8% vs. 2.6%, p=0.09) and MACE (15.7% vs. 6.9%, p= NS) tended to be lower in SES group than PES group. Conclusions: Both PES and SES implantation was safe, and both showed favorable clinical outcomes in STEMI patients undergoing primary angioplasty. SES appeared to be superior to PES in preventing neointimal hyperplasia.

      • KCI등재후보

        개흉술을 받는 한국 성인 판막 환자의 유의한 관상동맥

        최웅림 ( Uhng Lim Choi ),이선화 ( Sun Hwa Lee ),박재형 ( Jae Hyeong Park ),성석우 ( Seok Woo Seong ),김준형 ( Jun Hyung Kim ),이재환 ( Jae Hwan Lee ),최시완 ( Si Wan Choi ),정진옥 ( Jin Ok Jeong ),성인환 ( In Whan Seong ),이경석 ( 대한내과학회 2012 대한내과학회지 Vol.83 No.1

        Background/Aims: The identification of significant coronary arterial disease (CAD) is important to reduce perioperative ischemic insult and the possibility of repeated open-chest surgery in patients scheduled to undergo valvular surgery. However, there are no published data on the incidence of significant CAD in these patients. Thus, we examined the prevalence of significant CAD in patients scheduled to undergo valvular surgery. Methods: From January 2005 to June 2011, all consecutive adult patients diagnosed with significant valvular disease and scheduled for an elective open valvular operation were retrospectively investigated at Chungnam National University Hospital and Chonbuk National University Hospital. Patients who underwent emergent valvular operations due to acute aortic dissection or trauma and concomitant valvular operations at the time of coronary artery bypass graft (CABG) surgery were excluded. Results: During the study period, a total of 431 patients (58 ± 13 years old, 204 males) were included. The distributions of mitral (241 patients) and aortic valvular disease (230 patients) were similar. Coronary angiography was performed in 297 patients (68.9%). Of these, 36 (12.1%) showed significant CAD and 32 underwent concomitant CABG operations. Based on a multivariate analysis, the presence of CAD was significantly associated with old age (≥ 65 years old) [odds ratio (OR) = 3.081, 95% confidence interval (CI) = 1.372-6.921, p = 0.006], more cardiovascular risk factors (≥ 3) (OR = 3.002, 95% CI = 1.386-6.503, p = 0.005), and the presence of aortic stenosis (OR = 2.763, 95% CI = 1.269-6.013, p = 0.010). Conclusions: The incidence of significant CAD was 12.1% in adult patients who underwent valvular operations in Korea. CAD was more common in patients with old age, aortic stenosis, and multiple cardiovascular risk factors.

      • KCI등재

        서낙동강 유역 평강천의 수질 특성과 용수원에 따른 토마토 및 오이의 생육

        이한철(Han Cheol Rhee),조명환(Myeung Whan Cho),이시영(Si Young Lee),최경이(Gyeng Lee Choi),이재환(Jae Han Lee) (사)한국생물환경조절학회 2007 생물환경조절학회지 Vol.16 No.4

        본 연구는 서낙동강 유역 평강천의 수질을 분석하고 이 하천수의 대체 용수원으로 지하수나 빗물이 가능한지를 검토코자 수행되었다. 평강천의 염 농도(EC)는 계절에 따라 차이가 컸으며 갈수기인 3월~5월에는 EC 3.22~3.62dSㆍm?¹로 매우 높았고 성수기인 6월부터 점점 낮아져 9월에는 EC 2.37dSㆍm?¹까지 낮아졌다. 염 농도(EC)는 평강천의 위치에 따라 많은 차이를 보여 상류는 EC 0.71dSㆍm?¹, 중류는 2.38dSㆍm?¹, 하루는 3.02dSㆍm?¹였다. 초장, 생체중, 건물중 등 생육이 토마토, 오이 모두 하천수보다 빗물이나 수돗물에 좋았다. 평균과중은 토마토는 수돗물이 가장 무거웠으나 오이는 처리간에 유의차는 없었다. 착과수는 토마토, 오이 모두 하천수가 가장 적었으며 빗물과 수돗물 간에는 차이가 없었다. 수량은 토마토에서는 수돗물이 10,594㎏/10a으로 가장 많았으며 빗물, 하천수 순이었다. 오이는 각각 수돗물이 11,826, 빗물이 10855㎏/10a로 하천수보다 44, 33% 많았다. 토마토 과실의 품질에서 당도는 하천수가 다소 높은 경향이었으나 처리간에 차이가 없었으며 배꼽썩음과의 발생은 하천수가 가장 많았다. T-N 및 P의 함량은 토마토, 오이 모두 처리간에 차이가 없었으며 Ca 함량은 토마토에서는 하천수보다 빗물이나 수돗물이 많았고 오이에서도 같은 경향이었다. 반면 Na 함량은 Ca와 달리 하천수에서 가장 많았다. 이상의 결과에서 서낙동강 유역의 농업 용수원으로 하천수 대신 지하수나 빗물을 이용하면 토마토 생육에 효과적일 것이라 생각된다 This study was conducted to analysis the chemical properties of Peunggang river and investigate the effect of irrigation sources on the growth of tomato and cucumber. The salt concentration in Peunggang river was high by 3.22-3.62 dSㆍm?¹s from March to May and lower gradually from April to February of next year, which was also lower in upper stream than in middle or low stream of Peunggang river. The growth such as plant height, fresh weight and dry weight in tomato and cucumber was better in drain water and tap water irrigation than in PR water (Peunggang river) irrigation. Mean fruit weight was highest in the tap water, and that of cucumber was no significance in the treatments. The number of setting fruit was lower in the PR water than in the treatments, and which was no significance between rain water and tap water. The yield of tomato and cucumber was found to be highest by 10,594 and 11,826 ㎏/10a in tap water, respectively and also lowest in the PR water among the three treatments. The fruit quality, soluble solids of tomato shows a tendency to increase in the PR water as compared with the other treatment, and the rate of blossom-end rote was higher by 13.6% in the PR water. T-N and P content of tomato and cucumber were no significance in the treatments. Ca content was lowest, but Na content highest in the PR water. It was thought that a rain water and tap water as alternative irrigation source of a PR water were proper.

      • KCI등재

        초음파기구의 치근단 역충전와동형성 효율 및 치질에의 영향

        이재환,김성교 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.2

        The purposes of this study were to evaluate the efficiency of cavity preparation and to determine the incidence of tooth crack when root-end retrograde cavity preparation was done with ultrasonics. 91 distobuccal root-ends of extracted human maxillary first molars were cut by 3mm perpendicularly to the long axis of tooth using a slow speed diamond saw, retrocavities were prepared using a slow-speed no. 2 round bur as controls, and stainless steel ultrasonic tips of power settings of 1 through 10 as experimentals. Time consumed and the number of strokes used for the cavity preparation were measured and evaluated, and the incidence of tooth cracks was observed under a stereomicroscope. The results were as follows: For the retrograde cavity preparation, time and number of strokes used were decreased as the ultrasonic power setting increased(p<0.001). High power setting of ultrasonics induced significantly more tooth cracks than did the slo w-speed bur or low-and medium power setting of ultrasonics(p<0.05). Teeth with previous crack induced significantly more tooth cracks than those without previous one when high power setting of ultrasonics were used for the retrograde cavity preparation(p<0.001). Teeth with initial apical canal size of no. 10 induced significantly more crack than did those with size of no. 15 when low power setting of ultrasonics were used for the retrograde cavity prearation(p<0.05).

      • KCI등재후보

        연삭의 채터 발생과 연삭 숫돌 수명의 연관성에 대한 실험적 고찰

        이상태,이재환,정윤교,김재실 한국공작기계학회 2002 한국생산제조학회지 Vol.11 No.5

        The chatter to raise grinding operating is reduce the precision and the quality. In this study, In reply to AE signal and the normal force generated in the grinding operating were measured (1) the amplitude in the mathematical model of the normal force is the form as to transform an exponential (2) the chatter growth is minus point of an exponent. (3) From the observed wheel aspect after the chatter growth, it was to investigated the concern of the chatter growth and the wheel life.

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