동원(東垣) ${\ll}$비위론(脾胃論)${\gg}$ 수록(收錄) 처방(處方)의 치법(治法)에 대(對)한 문헌적(文獻的) 고찰(考察)

이윤희,황희정,김상찬,박순달,변준석,Lee, Yun-Hee,Hwang, Hui-Jeung,Kim, Sang-Chan,Park, Soon-Dal,Byun, Joon-Seok 대한한의학방제학회 2001 大韓韓醫學方劑學會誌 Vol.9 No.1

Objectives : 'Pi Wei Lun' is the principal medical work of Li Dongyuan's writings, which contains most of his medical theories. There are sixty-three prescriptions in 'Pi Wei Lun', and fifty-two of them were originated from him. This study was planned to present assistance to those who apply Dongyuan's theory clinically. Methods : We investigated those fifty-two prescriptions literary, and studied them from a viewpoint of the principle and method of treatment. Results : Dongyuan's fifty-two prescriptions can be classified into eight groups from the viewpoint of the principles and methods of treatment which are composed of 'tonify the spleen and stomach & elevate the spleen Yang', 'elevate the spleen Yang & expel fire', 'elevate the spleen Yang & relieve dampness', 'promote blood flow to eliminate blood stasis', 'invigorate the spleen', 'replenish Ki & and dispel phlegm', 'purgation with drugs warm in nature', and 'the other' eight methods. Conclusions : From above, we concluded that Dongyuan considered 'the primordial energy of the spleen and stomach' as the most important when making up prescriptions, but, at the same time, he used diverse methods of treatment on the ground of differentiation of syndromes.

학술 3 - 아프리카돼지열병(African Swine Fever) 임상증상 및 부검소견

이윤희,Lee, Yun-Hui 대한수의사회 2015 대한수의사회지 Vol.51 No.10

멀티미디어 시대의 대학

이윤희,Lee, Yun-Hui 한국대학교육협의회 1997 大學敎育 Vol.85 No.-

연속압입시험법을 이용한 재료의 강도 , 잔류응력 및 파괴인성 평가

이윤희,이정환,옥명렬,안정훈,권동일 ( Yun Hee Lee,Jeong Hwan Lee,Myoung Ryul Ok,Jeong Hoon Ahn,Dong Il Kwon ) 대한금속재료학회 ( 구 대한금속학회 ) 1997 재료강도 심포지엄 Vol.- No.-

근대 건축물에 사용된 서양식 목조 지붕 트러스의 구조요인 및 기타 영향요인에 관한 연구 - 공공기관이 관리하는 문화재 중 근대건축물 기록을 중심으로 -

이윤희,유혜란,권기혁,Lee, Yoon-Hee,Yu, Hye-Ran,Kwon, Ki-Hyuk 한국건축역사학회 2011 건축역사연구 Vol.20 No.4

Western style timber roof trusses used as typical roof structures of buildings during a modern period have been developed with the interactions with their facade and functionality. The shapes of trusses and member sizes have been diversely changed by the purposes of architects, historical circumstances, and structural characteristics. For this reason, the change in the shapes of western style timber trusses along the times is one of important technology assets demonstrating the development of their structures during the modern period. Therefore, the purpose of this paper is to find out their structural characteristics throughout parametric analysis of which parameters were determined from the collected and classified documents on western style timber roof structure built in the modern period carefully obtained from public institutions. Results of the parametric analysis are as follows. The number of king-post trusses and modified king-post trusses built between 1920 and 1937 reaches almost half of the total number of truss types investigated. The mean values of their spans, distances, tributary areas, and height are respectively, 10.5m, 2.4m, $24.37m^2$and 3.24m. The cross-section areas of trusses tend to reduce since the city construction law was enacted in 1920. Also, this study found that western architects usually used larger structural members than eastern architects and usages and finishing materials of roof trusses are not always considered as one of the important design parameters.

한국 성인의 심혈관질환에 영향을 미치는 위험요인: 요코티닌을 포함한 흡연행태 및 건강행태를 중심으로

이윤희,곽은미,조미래,Lee, Yoon Hee,Kwak, Eun Mi,Jo, Mirae 국제문화기술진흥원 2021 The Journal of the Convergence on Culture Technolo Vol.7 No.3

본 연구는 국민건강영양조사 제7기 2016~2018년도 자료를 이용하여 우리나라 성인의 심혈관질환 유병에 영향을 미치는 요인에 대해 규명하고자 하였다. 연구대상자는 7,290명, 자료는 SPSS 26프로그램으로 복합표본 빈도분석, 교차분석, 로지스틱 회귀분석을 실시하였다. 주요 결과로 40~59세 9.0배, 60세 이상 29.44배, 고졸 이하 1.26배, 소득수준 '하' 1.68배, 요코티닌 50ng/mL 미만 1.54배, 50~499.9ng/mL 1.56배, 하루 평균 흡연량 20개비 이상 1.48배, BMI 25kg/m² 이상 2.06배, 유산소운동을 실천하지 않는 경우 1.17배 심혈관질환 유병을 유의하게 증가시키는 것으로 확인되었다. 이상의 결과로 우리나라 성인의 심혈관질환 유병정도를 감소시키기 위해 흡연을 포함한 비만, 운동부족의 생활습관 개선이 필요하며, 고혈압, 이상지혈증등의 유병기간이 길어진 40세 이상의 연령층, 사회경제적 수준이 낮은 층에게 금연을 포함한 건강관리에 대한 적극적인 노력이 요구된다. This study was to find out the influence of urine cotinine in Korean adults on Cardiovasculardiseases using data from the seventh Korea national health and nutrition examination survey 2016-2018. The subjects were 7,290. The data were analyzed by frequency analysis, 𝞆2 test and logistic regression analysis using SPSS 26. The main findings were that 40-59 age, higher than 60 age, lower than high school level, Income status low, urine cotinine level under 50ng/mL, urine cotinine level 50-499ng/mL, Average cigarette per day over the 20 loosey, BMI 25g/m², no aerobic exercise, the prevalence of cardiovascular disease increased 9.0 times, 29.44 times,1.26 times, 1.68 times, 1.54 times, 1.56 times, 1.48 times, 2.06 times and 1.17 times, respectively. As a result, it is necessary to improve lifestyles such as obesity and lack of exercise, to reduce the prevalence of cardiovascular disease in Korean adults, and to pay attention to older age groups and low socioeconomic groups.

보중익기합대칠기탕(補中益氣合大七氣湯)과 Doxorubicin의 병용이 MKN-45의 항암효과에 미치는 영향

이윤희,김봉석,오중한,임희용,김동우,최빈혜,변준석,Lee Yun-Hee,Kim Bong-Suk,Oh Jung-Han,Lim Hee-Yong,Kim Dong-Woo,Choi Bin-Hye,Byun Joon-Seok 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.1

In order to evaluate the anti-tumor and synergic effect of BoJungIkKeeHapDaeChilKi-Tang on doxorubicin, the inhibitory concentration(IC), IC50 and IC90 of single use of doxorubicin and BoJungIkKeeHapDaeChilKi-Tang with their concomitant treatment against MKN-45(Human stomach carcinoma) was observed using MTT(Microculture Tetrazolium test) assay. In addition, their anti-tumor effects were also observed in the xenograft nude mice models agianst MKN-45 cell lines. BoJungIkKeeHapDaeChilKi-Tang has only mimic direct anti-tumor effect against to MKN-45 cell lines but they were decreased general depressed signs induced by implantation of tumor cell lines and increased the total WBC and lymphocyte numbers. So, it is considered or expected that BoJungIkKeeHapDaeChilKi-Tang extracts were reduced by the critical toxicity of doxorubicin and shows favorable synergic effect with doxorubicin and BoJungIkKeeHapDaeChilKi-Tang extracts.

전신조사방사선치료 시 Isodose Structure를 이용한 Field-in-Field Technique의 유용성 평가

이윤희,반태준,이우석,강태영,백금문,Lee, Yoon Hee,Ban, Tae Joon,Lee, Woo Seok,Kang, Tae Young,Back, Geum Mun 대한방사선치료학회 2013 대한방사선치료학회지 Vol.25 No.1

목 적: 본원에서는 전신조사방사선치료 시 양 팔을 몸에 붙이고 누워있는 환자에게 좌우 양방향으로 방사선을 조사한다. 누운 자세는 기준점 두께에 대하여 신체 다른 부위와 두께 차이가 크기 때문에 보상체의 제작이 필요하고, 기준 깊이(Umbilicus) 처방선량에 대하여, 양팔(Arms)로 가려지지 않은 흉부와 복부 전면(Anterior)은 최대 20%까지의 선량차이가 나는 고 선량 영역이 된다. 이에 본 연구에서는 전신조사방사선치료 시 고 선량 영역과의 선량 차이를 줄일 수 있는 Isodose Structure를 이용한 Field-in-Field (FIF) Technique의 유용성을 평가 하고자 한다. 대상 및 방법: 인체모형등가팬텀(Rando Phantom, Alderson Resarch Laboratories Inc. Stamford. CT, USA, With Arm)으로 전산화단층촬영모의치료기의 영상을 획득하여 FIF와 납(Pb) 보상체를 이용한 전산화치료계획(Eclipse, version 10.0, Varian, USA)을 수립하였다. 두 치료계획의 흉부와 복부 부위의 선량분포를 비교하고, 수립된 치료계획을 이용하여 인체모형등가팬텀에 선량을 조사한 후, 열형광선량계(thermoluminescence dosimeter, TLD)와 필름(Film)을 이용하여 측정하였다. 결 과: 두 치료계획을 비교해 본 결과 기준깊이 처방선량에 대하여 팔로 가려지지 않은 흉부와 복부 전면의 선량차이는 FIF에서는 106~107%, 납 보상체를 이용한 치료계획에서는 114~124%였다. 열형광선량계를 분석한 결과로 FIF에서는 104~107%, 납 보상체를 이용한 치료계획에서는 110~117%의 기준깊이 처방선량과의 선량차이가 나왔다. 결 론: 본 실험에서 인체모형등가팬텀에 양 팔을 제작하여 치료 계획 및 선량을 조사해 보았다. 양 팔의 투과 유무에 따라 약 7~17%의 선량차이가 발생 하였다. 4단계의 FIF 기법으로 3차원 치료계획을 수립하여 전신에 약 95~107%의 균등한 선량 분포를 확인하였고 ${\pm}10%$ 이내의 선량 균일성을 유지 할 수 있을 것으로 분석 되었다. FIF 기법을 이용한 3차원 치료 계획은 환자 전신에 조사되는 선량을 미리 분석 할 수 있는 치료 계획으로 기존 치료 방법보다 균등한 선량의 전달이 가능할 것으로 사료된다. Purpose: In Asan Medical Center, Two parallel opposite beams are employed for total body irradiation. Patients are required to be in supine position where two arms are attached to mid axillary line. Normally, physical compensators are required to compensate the large dose difference for different parts of body due to the different thicknesses compared to the umbilicus separation. There was the maximum dose difference up to 30% in lung and chest wall compared to the prescription dose. In order to resolve the dose discrepancy occurring on different body regions, the feasibility of using Fieid-in-Field Technique is investigated in this study. Materials and Methods: CT scan was performed to The RANDO Phantom with fabricated two arms and sent to Eclipse treatment planning system (version 10.0, Varian, USA). Conventional plan with physical lead compensator and new plan using Field-in-Field Technique were established on TPS. AAA (Anisotropic Analytical Algorithm) dose calculation algorithm was employed for two parallel opposite beams attenuation. Results: The dose difference between two methods was compared with the prescription dose. The dose distribution of chest and anterior chest wall uncovered by patient arms was 114~124% for physical lead compensator while Field-in-Field Technique gave 106~107% of the dose distribution. In-vivo dosimetry result using TLD showed that the dose distribution to the same region was 110~117% for conventional physical compensator and 104~107% for Field-in-Field Technique. Conclusion: In this study, the feasibility of using FIF technique has been investigated with fabricated arms attached Rando phantom. The dose difference was up to 17% due to the attached arms. It is shown that the dose homogeneity is within ${\pm}10%$ with the CT based 3-dimensional 4 step FIF technique. The in-vivo dosimetry result using TLD was showed that 95~107% dose distribution compared to prescription dose. It is considered that CT based 3-dimensional Field-in-Field Technique for the total body irradiation gives much homogeneous dose distribution for different body parts than the conventional physical compensator method and might be useful to evaluate the dose on each part of patient body.

보중익기합대칠기탕(補中益氣合大七氣湯)과 Doxorubicin의 병용이 3LL의 항암효과에 미치는 영향

이윤희,김봉석,오중한,임희용,김동우,최빈혜,김상찬,변준석,Lee Yun-Hee,Kim Bong-Suk,Oh Jung-Han,Lim Hee-Yong,Kim Dong-Woo,Choi Bin-Hye,Kim Sang-Chan,Byun Joon-Seok 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.1

In order to evaluate the anti-tumor and synergic effect of Bojungikkeehapdaechilkitang with doxorubicin, the inhibitory concentration(IC), $IC_{50}\;and\;IC_{90}$ of single use of doxorubicin and Bojungikkeehapdaechilkitang with their concomitant treatment against 3LL(Lewis lung carcinoma) was observed using MTT(Microculture Tetrazolium test) assay. In addition, their anti-tumor effects were also observed in the xenograft nude mice models agianst to 3LL cell lines. Bojungikkeehapdaechilkitang has only mimic direct anti-tumor effect against to 3LL cell lines but they were decreased general depressed signs induced by implantation of tumor cell lines and increased the total WBC and lymphocyte numbers. So, it is considered or expected that Bojungikkeehapdaechilkitang extracts were reduced the critical toxicity of doxorubicin and shows favorable synergic effect with doxorubicin and Bojungikkeehapdaechilkitang extracts.

PWR 사용후핵연료의 Li 환원과정 모사 프로그램 개발

이윤희,신희성,장지운,김호동,윤지섭,Lee, Yun-Hee,Shin, Hee-Sung,Jang, Ji-Woon,Kim, Ho-Dong,Yoon, Ji-Sup 한국방사성폐기물학회 2006 방사성폐기물학회지 Vol.4 No.4

In this paper a computer program was developed, which simulates the Li reduction process of PWR spent fuel, and the amount of a produced metal or chloride compound was calculated at the various amount of Li with the program. It establishes a database, which is composed of some characteristics related to a chemical reaction equation and thermodynamic data, and it calculates the transformed rate of PWR spent fuel oxide at the certain amount of Li by using the database as input data. As the results of the performance test of the program, it was validated that the transformed values of oxides, except for $Eu_2O_3$ and $Sm_2O_3$, were almost the same to within about a 6 % error with those calculated by the previous code and that the calculated amount of Li was also exactly consistent with the theoretical one, which is used for a complete reaction of each oxide in a single chemical reaction. A relationship between Li and the transformed metal of each oxide was analyzed on the basis of the quantities calculated with the verified development program. Of the results, when the amount of Li was given to be 250 mole, the 83.73 percentage of $UO_2$ was transformed into U while the remainder was still to be $UO_2$. In addition, it was appeared that the 297 mole of Li was needed to completely convert $UO_2$ into U.