Sprayed FRP 공법에 의한 콘크리트 구조물의 보수ㆍ보강법 개발에 관한 연구

이강석(Lee, Kang Seok),손영선(Son, Young-Sun),변인희(Byeon, In Hee),이문성(Lee, Moon Sung),나정민(Na, Jung-Min),이리형(Lee, Li-Hyung) 한국콘크리트학회 2006 한국콘크리트학회 학술대회 논문집 Vol.2006 No.11

Sprayed FRP 공법에 의한 콘크리트 구조물의 보수ㆍ보강법 개발에 관한 연구

이강석(Lee, Kang Seok),변인희(Byeon, In Hee),손영선(Son, Young-Sun),이문성(Lee, Moon Sung),이성호(Li, Cheng-Hao),이리형(Lee, Li-Hyung) 한국콘크리트학회 2006 한국콘크리트학회 학술대회 논문집 Vol.2006 No.11

MELAS 증후군에 동반된 만성 가성 장폐쇄증

한상훈 ( Sang Hoon Han ),홍수진 ( Su Jin Hong ),박정호 ( Jeong Ho Park ),박선아 ( Sun Ah Park ),이준성 ( Joon Seong Lee ),이문성 ( Moon Sung Lee ),성기범 ( Ki Bum Sung ),심찬섭 ( Chan Sup Shim ) 대한소화기기능성질환·운동학회 2008 Journal of Neurogastroenterology and Motility (JNM Vol.14 No.1

Mitochondrial DNA disorder is a heterogenous group of diseases that is related to disorders of mitochondrial (mt) energy metabolism. MELAS (mitochondrial encephalopathy with lactic acidosis and stroke-like episode) is a major maternally inherited multi-systemic disorder, in which 80% of cases are associated with mt DNA A3243G point mutation. The clinical course of MELAS is highly variable, ranging from asymptomatic to progressive muscle weakness, seizures, stroke-like episodes, encephalopathy with lactic acidosis and premature death. However, gastrointestinal symptoms in patients with MELAS are seldom documented. We report a 17-year-male with MELAS presenting chronic gastrointestinal pseudo-obstruction. We confirmed that he had the classical A3243G mt DNA point mutation.

생체외 ( In - Vitro ) 에서 직접 용해제에 의한 간내 담석 용해도의 고찰

박찬욱(Chan Wook Park),류권호(Kwon Ho Ryu),권강호(Kang Ho Kwon),이종태(Jong Tae Lee),이준성(Joon Seong Lee),김연수(Yun Soo Kim),이문성(Moon Sung Lee),황성규(Seong Gyu Hwang),김선주(Sun Joo Kim),심찬섭(Chan Sup Shim),(H . Igimi) 대한내과학회 1996 대한내과학회지 Vol.50 No.4

Objectives: The incidence of intrahepatic duct (IHD) stone is higher in east Asia including Korea than western contries. IHD stone has been regarded as a troublesome disease with poor surgical results. Recently, percutaneous transhepatic choledochoscopic lithotripsy with electrohydraulic lithotripsy of IHD stones showed good success rate, but it also couldn't remove stones in case of severe stenosis, acute angulation or peripheral impacted stones. A MTBE, widely used for dissolving cholesterol stone, was considered to be little effect for dissolving pigment stones. So we analysed IHD stones and dissolved them by direct solubilizer to investigate the dissolution rate of IHD stones. Methods. We have analyesd the compositions of 13 IHD stones removed during the percutaneous transhepatic cholangioscopy or pos-operative cholangioscopy by infrared spectrophotometer and dissoluted by direct solubilizer. Dry intact IHD stones were weighed and then inserted into 50ml glass tube. Within an 8hours incubation time, the 25ml of solvent were exchanged every 30minutes. After 2 and 8hours of incubation, the stone residue was dried-up at 60℃ for check weight reduction and compare to the initial dry weight. The solvent A medium was a 0.1M boric acid/sodium carbonate buffer (pH 9.4), EI)TA 1%(w/v), 1 M urea and solvent B was solvent A medium plus 0.04 M Lubrol PX and N-acethylcysteine. Results: The sites of dissolved IHD stons were both IHD stones 8cases(61.5%), left IHD stones 3(23.1%) and right IHD stones 2(15.4%), The components of IHD stones were calcium bilirubinate stones in 11cases(84.6%), followed by mixed stones 2 (15.4%). The dissolution rates after 2 and 8hours dissolution by solvent A is 11.7%, 24.7% and by solvent B is 25.7%, 62.7% respectively. The dissolution rates after 8hours in solvent B is higher than solvent A (p<0.05). Conclusion: In order to improve dissolution rates of IHD stones, the development of new solvent and the improvement of currently used solvents and methodology should be considered.

고령자 담석증의 임상적 고찰

차상우(Sang Woo Cha),천갑진(Gab Jin Chun),박용순(Yong Soon Park),송동화(Dong Hwa Song),조영덕(Young Deok Cho),김진오(Jin Oh Kim),봉형근(Hyung Keun Bong),조주영(Joo Young Cho),김연수(Yun Soo Kim),이준성(Joon Seong Lee),이문성(Moon Sun 대한소화기학회 1996 대한소화기학회지 Vol.28 No.2

N/A Background/Aims: Gallstone is uncommon before adolescence, and its incidence increases v:ith age. In elderly patients, one of the important characteristics of the ga]lstone disease is that they often have bile duct stones causing acute obstructive cholangitis. Another is that they could be accompained by other diseases. Methods: We analyzed 2,154 patients surgical]y or radiologically proven gallstone patients at the Soon Chun Hyang University Hospita] from l984 to 1994 and compared the clinical characteristics of elderly patients group(over 60 years) with younger patients group(under 60 years). Results: The peak incidence of gallstone (fisease wos noted in the 6th decade and the mean age was 55 years. Elderly patients group were 40.6%(874 cases) and younger patients group were 59.4%(l,280 cases'). Male to female ratio of eler]y patients vras I:1.IO. The location of stones was gallbladder(GB) in l,395 cases(64.9%), multiple sites in 416 cases(19.3%), common bile duct(CBD) in 214 cases(9.9%) and intrahepatic duct(IHD) in 129 cases(5.9%). In elderly patients group, the ]ocation of stones was multiple sites in l86 cases(2l.3%)and CBD in 120 cases(l3.7%). Frequency of stones in multiple sites and GB was significontly higher in elderly patients group than younger patients group(pO.OJ). The prominent clinical manifestations were right upper quadrant abdominal pain(24.5%), epigastric pain(19.4%), and no symptoms(l0.8%). In elderly patients group, chilling and jaundice were significantly higher than younger patients group(p 0.01). The associated diseases were cardiac diseases(l3.7%), diabetes me]litus(8.1%), malignancy (7.3%), liver cirrhosis(6.4%), and hepatitis(5.2%). Cardiac diseases, respiratory diseases, diabetes rnellitus and malignancy were more frequently associated in elder]y patients group than in younger group(p0.01). The incidence of complication was 10.7%(230/2,154)and mortality rate was 1.1% (24/2,154). In elderly patients group, the incidence of complication* and mortality* was signifi- cantly higher than younger patients group(*: p0.01; **: p0.05). Conclusions: The incidence of stones in CBD and mutiple sites, complication and morta]ity rate were higher, and chilling and jaundice were more frequently noted in elderly patients group than younger patients group. Our results suggest that ear]y diagnosis and proper treatment migbt be necessary in elderly patients with the gallstone disease. (Korean J Gastroenterol 1996; 28:260-266)

담석의 초음파상과 성분분석에 관한 비교 연구

송영식,김진홍,문철,이준성,이문호,김익수,김재준,김선주,이문성,조성원,심찬섭,유희,허경발,김훈식 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5

Although the treatment of gallbladder stones is mainly dependent on surgical intervention, recently medical treatment such as oral bill acid therapy, dissolution therapy with MTBE or extracorpareal shock wave lithotripy have been also performd. For the auccess, of these medical therapy. the composition of gallbaddser stones is a important factor. So, to predict the comical composition, we examined 100 cases of the surgically removed gallblraldder stoned by ultrasonaraphy. And we compared the ultrasonograplic findings of gallbladder stones with the chemical compotions and the features of cut surface. Alan we compared the presence of the calcification on the simple abdominal X-ray. The chemical components of gallbladder stones were analysed by ultrared spectrometer. Ultrasonographic findings were claesafied into five characeristic types; the shooting-star (SS) type, the crescent (C) type the half-moon (HM) kype, the full-moon (FM) type anal the star-dust (SD) type. The roved as fallows. In chemical compositions of gallstones, 67 cases (67%) were cholesterol stones with 26 eases (2^%) of pure cholesterol stones, and 30 cases (30%) of cholesterol-bilirubinate stones, bilruastnate stone were 25 cases (25%), calcium-carbanate stones were 7 cases (7%), and calcium pltcasphate stone was 1 case (1%). In ultrasonograhic fielding of gallstones, the SS types were 24 cases (24%), the C types 43 cases (43%), the FM types 16 uses (16%), the HM types 14 cases (14%) and the SD types were 3 cases (3%). In the relationship between tcltrasonographic findings and cheat composition, tine SS type itrcluded cholestro stones with 21 cases (88%). The C type included cholesterol stones with 30 cases (70%) and bilirubinate stones with 13 cases (13%). The HM types included chstrol stones with 9 cases (64%), bilruinate stones with 3 gases (24%) and calcium carbonate stones with 2 cases (14%). The FM types inch cholesterol stones with 5 cases (31%), bilirubinate stone with 6 cases (38%), calcium carbons a stones with 4 canes (25%), and calcium phosphate stone with 1 case (6%). The SD types incitude cholesterol stone with 2 cases (67%) and hilirubinatie stone with 1 case (33%). Cholesterol stone were found mainly in the C type (45%) and the SS type (31%). Bilirubinate stones were found mainly in the C type (52%) and the FM type (24%). In comparison between the presence of calcification on the simple abdominal X-ray and the chemical composition with ultrasonographic findings, 9 of 100 cases of gallbladder stones showed calcification on the simple abdominal X-ray with 2 choleBterol stonecs; 5 bilirulalnabe stone, 2 calciim carbonate stones. Non-cholesterol stones showed more frequent calcification finding than eholeacrol stones. In the features of the cut surfaces of the 100 gallbladder stones, the concenteric types were 64 cases (64%), the homogenous types were cases (26%), and to radiating types were 10 cases (10%). And there was no correlation between the features of the cutsurfaces of gallbladder stones and the ultrarsorographic findings. , In conclusion, the classification of ultrasonographic findings are useful to predict, the chemical compositions of gallblardder stones and to decide on the therapeutic method of gallbladder stones.

성범죄자 치료 프로그램이 심신장애 성범죄자의 인지 및 정서적 특성에 미치는 영향

김정현,최상섭,이문성,김선범,정지숙,김은혜,류미경 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : This study was investigated to prove the effectiveness of Cognitive Behavior Treatment Program in mentally ill sex offenders and to be used as basic data for development of optimized treatment program for mentally ill sex offenders. Methods : Cognitive Behavior Treatment Program was carried out over 10 weeks for 30 mentally ill sex offenders. With Interpersonal Responsiveness Index (IRI), UCLA Loneliness Scale (UCLALS), Coping Using Sex Inventory (CUSI) and Rape Myth Acceptance Scale (RMAS), the effectiveness of the treatment programme was evaluated. The data was analyzed with paired t-test. Results : The results with 23 subjects showed no significant score changes after treatment program in IRI and UCLALS .However, there was a statistically significant improvement in the scores of CUSI and RMAS. Conclusion : Despite several limitations, this study showed significant effects of Cognitive Behavior Treatment Program on mentally-ill sex offenders. Therefore, treatment focused on the changes of cognitive and emotional characteristics of sex offenders along with the treatment for main psychiatric illness should be provided for mentally ill sex offenders to prevent recidivism. More studies to develope optimized treatment programme for mentally ill sex offenders are needed in the future.

담도배액관의 폐색기전에 관한 연구 : 전자현미경소견 및 폐색물질의 성분분석을 중심으로 A Electron Microscopy Study and Analysis of the Clogging Material

김진홍,김홍수,이문성,조성원,심찬섭,조영덕,김선주 대한소화기내시경학회 1990 Clinical Endoscopy Vol.11 No.1

Endoscopic biliary stents provide effective palliation of malignant obstructive jaundice in patients who are not surgical candidates. Unfortunately the stents in current use have a tendency to block. The clogging phenomenon also severely restricts the value of stents in patients with benign strictures. We studied the mechanism of the occlusion of biliary stents to find ways to prevent it. We have examined 17 blocked stents by electron microscopy(EM), infrared absorption spectrophotometry, and bacteriological cultures. The mean time to stent clogging with 10 french stents was 131 days, and with 12 French stents was 143 days. The differece between the clogging time of the two stents was statistically not sigificant. Scanning EM showed that the internal surfaces of the stent were covered with bacteria embedded in a condensed fibrillar intercellular matrix. The bacteris form a surrounding fibrillar extracellular product which anchors them to the stent. Inorganic crystals were rarely seen, because they presumable dissolved during the fixing for EM. These EM findings are typical of a biofilm. As major components of the occluding material calcium bilirubinate was identified in 15 stents by infrared absorption spectrophotometry. 7 different microorgainsms were isolated from the 17 blocked biliary stents. 6 of the isolates were gram-negative, and 1 was gram-positive. The most frequently isolated genus was Escherichia, which was found in 8 stents, followed by proteus, Pseudomonas, and Morganella, which was found in 2 stents respectvely. We propose that stent colgging is initiated by bacterial adhesion and growth of a biofilm. The bacteria then deconjugate bilirubin in bile and the lumen is progressively occluded by deposition of calcium bilirubinate and further biofilm formation.

십이지장의 Brunner`s Gland 선종 2예

김영선,이동화,김익수,김진홍,이문성,조성원,심찬섭,조영덕,고은석 대한소화기내시경학회 1990 Clinical Endoscopy Vol.10 No.2

So-called Brunners gland adenoma is characterized by a nodular proliferation of histologically normal Brunners gland, accompanied hy duots and scattered stromal elements. This benign tumor of the duodenum is rare and is not eaey to discover because of non-specific symptoms. The clinical presentation can vary from vague upper abdominal symptoms with dyspepsia and nausea to diarrhea, jaundice, obetruction and gastrointestinal bleeding. The diagnosis is usually made by radiologic studies and gastroduodenal endoscopy which can also provide definitive treatment. The management of Brunners gland adenoma is complete removal of the lesion and pathologic examination, always necessary to define the nature of the lesion and exclude malignacy. We experienced two cases of Brunner's gland adenoma in the duodenal bulb. The patients complained of epigastric discomfort and bloating respectively. The endoscopic examination revealed round semipedunculated polypoid mass covered with normal muosa at duodenal bulb. One case with a small adenoma (size: 0.7 x 0.7 cn) had been removed by endoscopic polypectomy and the other case with a relatively large polyp (aize: 2.0x2.0cm) had been treaed by transduodenal exploration and excision of the polyp.

내시경적 정맥류 결찰요법 (EVL) 중 발생한 식도천공 1예

박찬욱,이준성,김홍수,이문성,김선주,심찬섭,박형주,이광희 대한소화기내시경학회 1995 Clinical Endoscopy Vol.15 No.2

Endoscopic variceal ligation(EVL) was developed to provide a safer alternative than injection sclerotherapy for treatment of bleeding esophageal varices. EVL adds a new indication that will significantly increase the use of overtubes. overtube itself may have a role in predisposing to esophageal perforation but only one report has been published regarding an esophageal perforation related to the placement of an overtube. Recently, we experienced a case of esophageal perforation caused by overtube placement during endoscopic variceal ligation. So we report this case with review of relevant literatures.