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신생아에서의 Nitroblue Tetrazolium 검사에 대한 연구
박성근,인수미,장미영,변상현 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1
Purpose : Nitroblue Tetrazolium(NBT) reduction test is ingested by a normal phagocytic neutrophil. It's use on the observation that neutrophil reduction of NBT to an intracellular formazan precipitate by superoxide. Author designed this study to identify the effectiveness of NBT test for prediction of neonatal infection. Methods : In this study, 49 cases of non-infected neonates(Group A, 26cases) and infected cases(Group B, 23cases) who had been admitted at the NICU of Chungnam National University Hospital from June to September, 1998, were included. Author performed NBT tests of two samples on admission(NBT1) and on the 7th day of hospitalization(NBT2) in each group. Results 1) Mean age at NBT1 was 4.00±2.69 days in group A, 3.37±2.87 days in group B, at NBT2 was 11.07±2.70 days in group A, 10.37±2.87 days in group B. 2) NBT1 value was 58.75±28.50% in group A and 55.00±28.23% in group B. NBT2 value was 33.42±19.58% in group A and 40.76±29.32% in group B. There was no significant difference of NBT1 and NBT2 between group A and B. Normal infants, NBT value had higher positive value than other reference values. When infants were infected & normal infants had increased NBT value. 3) In group B, apparent symptoms did not give any influences to the value of NBT1 and NBT 2 significantly. There was no significant difference on NBT test results according to the isolation of pathogen. Conclusion : During neonatal period, there would be false positive & false negative value of NBT test. So, to define infection of neonate, We should consider clinical manifestations & other laboratory findings.
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박성근 국어교육학회(since1969) 2024 국어교육연구 Vol.- No.84
The purpose of this study is to introduce poetic discussions on ‘speakers’ in modern poetry and explore the direction for education on speakers in modern poetry through that. The traditional view of understanding speakers as the poets was discarded before the aesthetics and autonomy of poetic text, and a fictional speaker separated from the poet appeared as the origin and substance of voices revealed in poetic text. It can be said that it is inevitable to establish a fictional speaker because it is possible to have imaginative and post-subjective experience through the fictional speaker and communicate and share emotions with various readers based on that. Meanwhile, today, in modern poetry, a single poetic text with multilayered voices inside continues to appear, exposing a problem that it is difficult to explain it only with the fictional speaker of a single voice. This led to the birth of a speaker with a divided and multiplying voice that exists inside the poetic text. With the emergence of that new speaker, the theory of speakers is also being modified. It is necessary to reignite the discussion of the speaker, viewpoint, and tone continuously in that the components of poetics can be renewed with the literature of ‘here, now’ only when it is descriptive rather than normative. Furthermore, these discussions in the space of literature need to be transferred to that of education. Until now, education on speakers had the problem of not reflecting the contemporaneity of literature and readers sufficiently as it used poetic texts putting forth the speaker with a single voice while the concept of speakers was missing. For the complete acceptance and production of poetic texts, it is needed to establish the existence of a fictional speaker and intertextually utilize the poetry texts of ‘here, now’ which contain not just a single subjective voice but also other voices that are present complexly. Through this, it will be possible to allow learners’ literary experience to be transferred to literary skills soundly and lead future adult readers’ active literary activities. 이 연구는 현대시 ‘화자’에 관한 시학적 논의들을 소개하고 이를 통해 현대시 화자 교육의 방향을 탐색하는 데 목적이 있다. 화자를 시인과 동일하게 이해하는 전통적인 관점은 시 텍스트의 심미성과 자율성 앞에서 폐기되었고, 시 텍스트에 드러나는 목소리들의 진원이자 실체로서 시인과 분리된 허구적 화자가 출현하게 되었다. 허구적 화자를 통해 상상적이고 탈주체적인 체험이 가능해지고 이를 통해 다양한 독자들과 소통하고 정서를 공유할 수 있다는 점에서 허구적 화자의 정립은 필연적이라고 할 수 있다. 한편 오늘날 하나의 시 텍스트 내부에 다층적인 목소리를 가진 현대시가 지속적으로 출현하고 있으며, 이는 다시 단일한 목소리의 허구적 화자만으로는 해명하기 힘든 문제를 노출시켰다. 이는 시 텍스트 내부에 존재하는 분열되고 증식되는 목소리를 가진 화자의 탄생을 예비했다. 새로운 화자의 등장과 더불어 화자에 관한 이론도 함께 수정되고 있다. 시학의 구성 요소들은 규범적이라기보다는 기술적(記述的)일 때 비로소 ‘지금, 이곳’의 문학과 함께 갱신될 수 있다는 점에서 화자와 시점, 어조에 관한 논의를 지속적으로 재점화할 필요가 있다. 나아가 문학공간에서의 이러한 논의들이 교육공간으로 전이될 필요가 있다. 그간의 화자 교육은 화자 개념이 부재한 가운데 단일한 목소리를 가진 화자를 내세운 시 텍스트들을 주로 활용함으로써 문학과 독자의 동시대성을 충분히 반영하지 못한 문제점을 갖고 있었다. 시 텍스트의 온전한 수용과 생산을 위해서는 허구적 화자의 존재를 정립하고 단일한 주체적 목소리뿐 아니라 타자적 목소리들이 혼재한 ‘지금, 이곳’의 시 텍스트들을 상호텍스트적으로 활용할 수 있어야 한다. 이를 통해 학습자의 문학 경험이 문학 능력으로 온전히 전이되어 미래 성인 독자의 능동적인 문학 활동을 견인할 수 있을 것이다.
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박성근,류재홍,최중명,서민우,박정민 대한의학회 2016 Journal of Korean medical science Vol.31 No.3
Although non-alcoholic fatty liver disease has been reported as a cardiometabolic risk factor, the effect of non-alcoholic fatty liver is yet to be clarified on abdominal obesity. Therefore, this study was conducted to investigate the longitudinal relationship of nonalcoholic fatty liver on the development of abdominal obesity. The study participants were composed of 11,212 Korean men without abdominal obesity. They were followed up from 2005 to 2010 to be monitored for the development of abdominal obesity according to their degree of non-alcoholic fatty liver disease (normal, mild, and moderate to severe). Cox-proportional hazard model was used to calculate the hazard ratios for abdominal obesity according to the degree of non-alcoholic fatty liver disease. While the average incidence was 15.5%, the incidence of abdominal obesity increased according to the degree of non-alcoholic fatty liver (normal: 11.6%, mild: 25.2%, moderate to severe: 41.0%, P < 0.001). Multivariable-adjusted hazard ratios for abdominal obesity independently increased proportionally to the degree of NAFLD (mild [1.07; 0.94-1.23], moderate to severe [1.58; 1.11-2.26], P for trend < 0.001). The risk of abdominal obesity increased proportionally to the degree of non-alcoholic fatty liver disease. This finding guarantees further studies to reveal the incidental relationship of abdominal obesity with non-alcoholic fatty liver disease.
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KLN 스퍼터링용 타겟의 제조 및 코닝 1737 유리 기판위에 성장시킨 박막의 광학적 성질
박성근,서정훈,김성연,전병억,김진수,김지현,최시영,김기완,Park, Seong-Geun,Seo, Jeong-Hun,Kim, Seong-Yeon,Jeon, Byeong-Eok,Kim, Jin-Su,Kim, Ji-Hyeon,Choe, Si-Yeong,Kim, Gi-Wan 한국재료학회 2001 한국재료학회지 Vol.11 No.3
rf-마그네트론 스퍼터링 방법을 이용하여 높은 광투과성을 지니며 c-축 배향된 KLN 박막을 제작하였다. 하소 및 소결 과정을 거쳐서 균일하고 안정한 상태의 KLN 타겟을 제조하였다. KLN 타겟은 화학량론적인 조성 및 K가 30%, 60%, 그리고 Li가 각각 15%, 30% 과량된 조성을 사용하였으며 K와 Li의 휘발을 방지하기 위하여 낮은 온도에서 소결시켰다. 제조된 타겟을 사용하여 rf-magnetron sputtering 방법으로 박막을 제조하였으며, 이때 K가 60% Li가 30% 과량된 타겟으로 제조할 때 단일상의 KLN 박막을 얻을 수 있었다. KLN 박막은 코닝 1737 기판 위에서 우수한 결정성과 높은 c-축 배향성을 나타내었으며, 이때 박막의 성장조건은 고주파 전력 100 W, 공정 압력 150 mTorr, 기판 온도 58$0^{\circ}C$였다. 가시광 영역에서 박막의 투과율은 약 90% 이고, 흡수는 333 nm에서 발생하였으며 632.8 nm에서 박막의 굴절율은 1.93이었다. Transparent and highly oriented KLN thin films have been grown by an rf- magnetron sputtering deposition method. A homogeneous and stable KLN target was prepared by calcine and sintering process. For KLN target, stoichiometry and composition excess with K of 30% and 60%, and Li of 15% and 30% respectively, was prepared. The targets were sintered at low temperature to prevent vaporization of K and Li. KLN thin films were fabricated by rf-magnetron sputtering method using those targets. In this experiment, using the target of composition excessed with K of 60% and Li of 30%, single phase KLN thin film was produced. KLN thin film has excellent crystallinity and highly c-axis oriented on Corning 1737 substrate. Transmittance of thin film in visible range was 90%, absorption edge is 333 nm and refractive index at 632.8 nm was 1.93.
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Pt 코팅된 Si 기판에 제조한 KLN 박막의 구조적 특성
박성근,이기직,백민수,전병억,김진수,남기홍 한국전기전자재료학회 2001 전기전자재료학회논문지 Vol.14 No.5
KLN thin films were fabricated on Pt coated Si(100) wafer using an rf-magnetron sputtering method. The grown KLN thin film consists of 4-fold grains. In this experiment, the structure of 4-fold grained thin film was investigated using XRD and SEM measurements. Pt layer was also deposited using the rf-magnetron sputtering method,. XRD measurement showed that he Pt thin film has Gaussian distribution form with strong (111) direction orientation. The KLN thin film has preferred-orientation of (001) direction, and the peak consists of 2 separate peaks; one with broad FWHM and the other with narrow FWHM. The sharp peak is due to single crystal, and combining with Em results, the 4-fold grain consists of singel crystals with c-axis normal to substrate.
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