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만성 간질환의 진행 정도 평가를 위한 비침습적 검사들의 상관관계와 임상적 의의
박근태,전대원,유영조,최춘식,정진웅,김진배,윤병철,최호순,함준수,박경남,이민호,이재원 (Geun Tae Park,Dae Won Jeon,Young Jo Yoo,Choon Shik Choi,Jin Woong Jung,Jin Bae Kim,Byoung Chul Yoon,Ho Sun Choi,Joon Soo Hahm,Kyoung Nam Park,Min Ho Le 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6
Background/Aims: We aimed to figure out a correlation of non-invasive tests for the diagnosis o chronic active hepatitis (CAH) or liver cirrhosis (LC). Methods: We measured the levels of serum albumin, bilirubin, alanine aminotransferase (ALT), asparate aminotransferase (AST), cholesterol prothrombin time, ICG-Rmax and shunt index (heart/liver ratio) in 174 patients with CAH and 80 patients with LC (Child A, 73 patients; Child B, 7 patients). A correlation of these values to evaluat the progression to liver cirrhosis was figured out from the multiple regression analysis. Results: There were significant differences between CAH patients and LC patients in the ratio of ALT to AST (ALT/AST, 1.45 ±0.05 vs 0.99 ±0.05), prothrombin time (93.9 ±1.2% vs 77.1 ±2.4%), ICG-Rmax (2.11 ±0.15 vs 1.07 ±0.12) and shunt index (0.21 ±0.00 vs 0.60 ±0.03). The multiple regression analysis of non-invasive tests yielded a formula, Y=3.3431 -0.8160 ×ALT/AST -0.0343 ×prothrom-bin time +2.6963 ×shunt index & p=ey/(ey+1), which can estimate the progression of chronic liver disease. The p value was less than 0.7 in 126 (96.2%) of 131 CAH patients, while 47 (68.1%) o69 LC patients showed p value over 0.7. Conclusions: When the p value mentioned above exceed 0.7, CAH is likely to develop into an early LC. These results suggest that the formula inferred from the multiple regression analysis of non-invasive tests may be used to evaluate the progression of chronic liver disease without the repeat of liver biopsy. (Kor J Gastroenterol 1999;33:799 - 807)
국내 연안에서 분리한 Vibrio vulnificus의 특성
박근태,박민정,정초록,송춘복,이제희,여인규,전유진,허문수,Park Geun-Tae,Park Min Jung,Jung Cho-Rok,Song Choon-Bok,Lee Jehee,Yeo In-Kyu,Jeon You Jin,Heo Moon-Soo 한국생명과학회 2004 생명과학회지 Vol.14 No.6
Five strains of Vibrio vulnificus, which cause serious septicemia in human worldwidely, was isolated from marine environments of Korea costal area from May to July of 2002. The isolated strains were identified by API 20E kit and partial 16S rDNA sequence analysis. 16S rDNA sequence of the isolates showed $99\%$ similarity with V. vulnificus ATCC 27562. The proteins of V. vulnificus isolates were examined by analyzing patterns of the cell lysates and outer membrane proteins (OMP). The OMP separated from cell lysates showed the common protein band. Therefore OMP profiles might be useful for the identification of V. vulnificus sp.
페놀분해세균인 Pseudomonas sp. EL-04J로부터 Trichloroethylene 분해효소의 확인
박근태,김호성,손홍주,이건,박성훈,이상준,Park, Geun-Tae,Kim, Ho-Sung,Son, Hong-Ju,Lee, Gun,Park, Sung-Hoon,Lee, Sang-Jun 한국생명과학회 2002 생명과학회지 Vol.12 No.5
Pseudomonas sp. EL-041 was previously isolated from phenol-acclimated activated sludge. This bacterium was capable of degrading phenol and cometabolizing trichloroethylene (TCE). In this study, we report the identification of trichloroethylene- degrading enzyme in Pseudomonas sp. EL-041 by the investigation of enzyme activity and DNA sequencing of specific phenol oxygenase gene. As the results of experiment, trichloroethylene-degrading enzyme in Pseudomonas sp. EL-041 was monooxygenase and suspected to phenol hydroxylase.
박근태 ( Geun-tae Park ),배지은 ( Ji-eun Bae ),김진욱 ( Jin-wook Kim ),김항준 ( Hang-joon Kim ) 한국정보처리학회 2009 한국정보처리학회 학술대회논문집 Vol.16 No.2
본 논문은 가상 골프 시스템에서 골프 공의 구질을 찾기 위한 새로운 센싱시스템을 제안한다. 제안된 시스템은 2 개의 수평 센싱라인과 한 개의 광원으로 구성된 간단한 구조이다. 센서 위에 드리워진 공과 클럽의 그림자 정보를 0,1 의 binary 형태로 만들어 놓은 원시데이터는 PC 로 보내지게 되고 PC 는 원시 데이터에서 공과 클럽의 영역들을 구분한다. 구분된 각각의 그림자 영역에서 속도나 초기 움직임 방향, 각도 등이 계산된다. 그리고 계산된 특징 정보를 이용해서 골프 공의 구질을 측정하고 제안된 센싱시스템의 효율성을 보인다.
박근태 ( Geun Tae Park ),전대원 ( Dae Won Jeon ),유영조 ( Young Jo Yoo ),최춘식 ( Choon Shik Choi ),정진웅 ( Jin Woong Jung ),김진배 ( Jin Bae Kim ),윤병철 ( Byoung Chul Yoon ),최호순 ( Ho Sun Choi ),함준수 ( Joon Soo Hahm ),박경 대한소화기학회 1999 대한소화기학회지 Vol.33 No.6
Background/Aims: Pseudocysts of the pancreas are a localized collection of fluid occurring within pancreatic mass or peripancreatic region and are enclosed by a fibrous tissue wall. The diagnosis and follow-up of the disease has been facilitated with the advent of ultrasound and computed tomographic scanning. In terms of therapy, surgery was the only option available in the past. Recently, new me thods such as percutaneous catheter drainage and endoscopic cystenterostomy are used. The aim o this study was to review the characteristics and results of various therapeutic methods for the management of pancreatic pseudocysts. Methods: We reviewed retrospectively 42 cases of pancreatic pseudocysts admitted at the Kangbuk Samsung Hospital from January, 1985 to December, 1997 Results: Twenty-six patients (61.9%) were managed non-operatively, and the remaining 16 patients were treated operatively. Twenty-seven patients (64.3%) had showed complete resolution of pseudo cysts ultrasonographically or roentgenographically with a mean follow-up period of 8.9 months. One operative and seven underlying disease-related deaths occurred. Conclusions: There are various management methods for pancreatic pseudocysts such as expectant treatment, operation, percutaneous catheter drainage and endoscopic cystoenterostomy. Thus, it is important to choose the appropriate management method considering the status of each individual patient. (Kor J Gastroenterol 1999;33:831 - 836)
박근태(Park Geun Tae) 한국신석기학회 2011 한국신석기연구 Vol.- No.21
신석기시대 석기는 용도별로 수렵구, 어로구, 채집농경구, 식료가공구, 가공구(목공구, 석기가공구), 의례활동이나 치레걸이로 사용되는 장신구로 분류할 수 있다. 제주도 신석기시대 유적에서 출토된 석기를 용도별로 분류하고 시기별, 유적별 조합상을 통해 신석기시대의 전반적인 생업활동 양상을 파악하였다. 초창기단계에는 모든 용도의 석기가 다양하게 확인되고 있다. 후기구석기시대의 가압박리에 의한 석기제작 방법으로 세석핵, 첨두기, 석촉, 밀개, 긁개, 새기개 등 격지를 이용한 소형석기가 제작되었고 더불어 다양한 형태의 갈돌, 갈판 등 식료가공구가 사용되었다. 따라서 생업활동은 적극적인 수렵과 채집활동을 영위하면서 부수적으로 어로활동이 행해졌던 것으로 추정된다. 조기단계에는 수렵구가 급감하고 새롭게 어망추가 확인되고 있다. 석기의 비중은 석재가공구와 식료가공구가 중심이 된다. 따라서 채집활동 중심의 생업활동을 영위하면서 수렵과 어로가 부수적으로 행해졌던 것으로 추정된다. 전기단계에서는 수렵구와 석재가공구·목재가공구가 확인되지 않고 어망추는 계속 사용고 있는 것으로 나타나고 있다. 석기의 비중이 식료가공구에 한정되어 나타나는 것으로 볼 때 생업활동은 채집활동이 중심이 되고 어망에 의한 어로활동이 부수적으로 행해진 것으로 보인다. 후·만기단계는 수렵구는 확인되지 않고 어로구 중 결합식조침이 사용되고 있다. 지석의 비중이 높아지며 골각기가 어로구 위주로 제작되어 성행하고 있다. 대형의 굴지구가 발달된 형태로 확인되는데 이는 채집생활을 넘어선 원시적인 농경생활을 영위했던 것으로 추정할 수 있다. 후기 단계 이후 다양한 생업경제활동은 식료의 안적인 공급을 유도하여 거주집단의 규모가 늘어나게 되면서(인구의 증가) 제주전역으로 유적이 확산되고 패총이 형성되고 있다. Stone tools in the Neolithic Period can be divided into tools for hunting, fishing, gathering, cooking, manufacturing (wood and stone working tools) and ornaments for ceremonies and decorations. After classifying the Stone tools found at the Neolithic sites in Jeju Island on their purposes, activities for livlihood in the Neolithic Period are estimated with combinations of features of periods and sites. In the Incipient stage, in general, a variety of Stone tools for different purposes are identified. The method for producing Stone tools through punch or pressure flaking technique in the Upper Paleolithic Period is to use flake such as point, arrowhead, end-scraper, side-scrape, burin and make a small stone tools. Also, various forms of cooking tools such as stone grinding pestle, grinding pestle are used. It is estimated that hunting and gathering are considered as an aggressive action for livlihood and fishing as an incidental activity. In the initial stage, fishing net-sinker is found with the decrease of hunting tools. Stone working tools and cooking tools are the main Stone tools. Therefore, the major activities for living are not hunting and fishing but gathering. In the early stage, hunting tools wood and stone working tools are not identified and fishing net-sinker continues to be used. Stone tools are only made for cooking tools. Fishing is subordinate to gathering which is essential for living. In the Late -Final stage, there are no hunting tools found and two-piece hook among fishing tools is used. As the stone chisel increases, bone implement mainly used for fishing became popular. Large digging tools is identified in an advanced form, which shows the possibility of primitive agricultural life beyond gathering. After in the late stage, many kinds of economic activities for livlihood lead to stable supply of food and growth of population size. As the population increases, the sites are expanded to the entire Jeju and Shell Mound is formed.