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      • KCI등재

        Characteristics of Rare Isotope Beams in the KoRIA Facility

        류민상,Byoung Hwi Kang,김용균,정순찬,윤종철 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.60 No.1

        The Korea Rare Isotope Accelerator (KoRIA) facility plans to provide neutron-rich rare isotopes (RIs) and stable heavy ion beams for research in the fields of basic and applied sciences. In the facility, both the isotope separator on-line (ISOL) and the in-flight fragmentation (IFF) methods are employed for RI production by 238U fission, which is effective for producing neutron-rich RI beams. These ISOL and IFF systems are designed to obtain world-class RI beam intensity, which allows exotic nuclei near the neutron drip line in the nuclear chart, which have not yet been explored, to be studied. In this paper, the uniqueness of the KoRIA facility under consideration, compared to other facilities, is described, and we present the characteristics of the RI beams that will be available at KoRIA. The Korea Rare Isotope Accelerator (KoRIA) facility plans to provide neutron-rich rare isotopes (RIs) and stable heavy ion beams for research in the fields of basic and applied sciences. In the facility, both the isotope separator on-line (ISOL) and the in-flight fragmentation (IFF) methods are employed for RI production by 238U fission, which is effective for producing neutron-rich RI beams. These ISOL and IFF systems are designed to obtain world-class RI beam intensity, which allows exotic nuclei near the neutron drip line in the nuclear chart, which have not yet been explored, to be studied. In this paper, the uniqueness of the KoRIA facility under consideration, compared to other facilities, is described, and we present the characteristics of the RI beams that will be available at KoRIA.

      • KCI우수등재

        심층신경망을 이용한 Total Ionizing Dose 및 Displacement Defect에 의한 Saddle Fin DRAM의 열화 특성 예측

        류민상,하종현,이경엽,서민기,방민지,이다복,김정식 대한전자공학회 2023 전자공학회논문지 Vol.60 No.11

        본 논문에서는 saddle fin dynamic random access memory (DRAM) 에 대한 total ionizing dose (TID) 와 displacement defect (DD) 영향을 Technology Computer-Aided Design (TCAD) simulation과 deep neural network (DNN) 를 사용해 조사하였다. Trap의 energy level, 농도, 위치 그리고 면적을 변수로 설정하였고, TCAD를 사용하여 saddle fin DRAM의 전류-전압 특성 dataset을 생성하였다. TCAD dataset을 전처리 과정을 거친 경우와 전처리를 하지 않은 경우로 나누어 DNN의 예측 정확도를 비교하였다. 그 결과 전처리 과정을 거쳐 훈련된 모델은 전처리 과정을 하지 않은 훈련 모델보다 mean square error (MSE) loss가 80 % 증가함과 동시에 R2 score가 37 % 증가하였다. 따라서 DNN을 활용한 정확한 예측을 위해서는 전처리 과정이 필수적이다. In this paper, the effects of total ionizing dose (TID) and displacement defect (DD) in saddle fin dynamic random access memory (DRAM) are investigated using technology computer-aided design (TCAD) simulation and deep neural network (DNN). TCAD is used for generating the current-voltage characteristic data of the saddle fin DRAM and the energy level, concentration, location, and area of the trap are utilized for variables. The TCAD dataset is divided into preprocessed and un-processed cases to compare the prediction accuracy of DNN. The result shows that the model trained with preprocessing has an 80 % increase in mean square error (MSE) loss and a 37 % increase in R2 score compared to the training model without preprocessing. Therefore, preprocessing of a dataset is necessary for high prediction accuracy using DNN.

      • KCI등재

        IBDV에 대한 단크론항체 생산 및 진단적 응용

        류민상 ( Min Sang Ryu ),송윤기 ( Yoon Ki Song ),이승철 ( Seung Chul Lee ),모인필 ( In Pil Mo ),강신영 ( Shien Young Kang ) 한국동물위생학회 2011 한국동물위생학회지 (KOJVS) Vol.34 No.1

        Infectious bursal disease (IBD) caused by infectious bursal disease virus (IBDV) is a highly contagious viral disease in chicken. It causes heavy economic loss by immune suppression and high mortality. The IBDV, designated Avibirnavirus in the Family Birnaviridae, has a double-stranded RNA genome formed by two segments, segment A and segment B. Segment A encodes a 108KDa polypeptide that is self-cleaved to produce pVP2, VP3 and VP4, and later pVP2 is cleaved to VP2. The VP2 contains the antigenic regions responsible for elicitation of neutralizing antibodies and VP3 is a major immunogenic protein of IBDV. In this study, monoclonal antibodies (MAbs) specific for IBDV were produced and characterized. All 15MAbs were specific for IBDV and did not react with other viruses used in this study. The protein specificity of MAbs was determined by comparing the reactivity patterns of each MAb with IBDV VP2 and VP234 recombinant baculoviruses and Western blot analysis. As a result, 7MAbs (1F5, 2C8, 2F4, 3C7, 4C3, 6F11, 6G5) and 5MAbs (2A4, 2G2, 3F5, 3G2, 4F10) were specific for VP2 and VP3, respectively. The protein specificity of 3MAbs (2B8, 3F7, 3F8) were not determined. Five (2C8, 2F4, 4C3, 6F11, 6G5) of the VP2-specific MAbs had a neutralizing activity against IBDV. Some MAbs reacted with IBDV-infected bursa of Fabricius by indirect fluorescence antibody (IFA) and immunohistochemistry (IHC) assay. The MAbs produced in this study would be used for diagnostic reagents for the detection of IBDV infection.

      • KCI등재

        Gas Mixture Dependence of the Performance for Multigap Resistive Plate Chambers in the Avalanche Mode

        조미희,홍병식,이경세,류민상 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.5

        We have investigated the performance of prototype multigap resistive plate chambers in the avalanche mode using cosmic ray muons for various gas mixtures. In the operational high-voltage plateau region, the efficiency is larger than 90%, the best time resolution is 123 ps, and the fraction of the non-Gaussian tail in the time spectrum is about 15%. The slewing corrections significantly improve the time resolution by about 40% at 6.4 kV, which is the operational high voltage. Although the addition of SF₆ to the gas mixture is necessary for avalanche mode operation, a relatively small fraction is preferrable for a better time resolution. The present results demonstrate that the current multigap resistive plate chambers can be used for charged particle identification at high momentum in real collision experiments.

      • KCI우수등재

        심층신경망을 이용한 3D Vertical SONOS NAND Flash의 Grain Boundary Distribution과 Geometrical Variation에 의한 전기적 특성 변동 분석

        하종현,방민지,이다복,서민기,류민상,김정식 대한전자공학회 2024 전자공학회논문지 Vol.61 No.4

        Planar 형태의 NAND Flash memory의 Scaling down의 한계로 3D Vertical Silicon-Oxide-Nitride-Oxide-Silicon (SONOS) NAND가 개발되었다. 3D Vertical SONOS NAND로 한정된 크기의 wafer에서 많은 transistor를 적층하여 planar type보다 더 많은 memory capacity를 확보할 수 있다. 하지만 vertical 구조로 변경되면서 공정 난이도 상승과 함께 공정에 소모되는 비용이 증가했다. 그래서 공정에 투입되는 비용을 줄이고 소자의 전기적 특성을 빠르고 정확하게 예측하는 기술의 필요성이 대두되었다. 본 논문에서는 TCAD simulation과 딥러닝을 통해 3D Vertical SONOS NAND의 polysilicon grain boundary distribution (Max-angle, Ycut, Xseed, Yseed, Aseed)과 geometrical variation (Width, Lcg)에 따른 전기적 특성 (Vtgm, Vti) 변동을 예측하고 분석했다. TCAD simulation 결과값을 바탕으로 학습한 딥러닝을 통해 전기적 특성을 예측했고 매우 높은 수치의 R2 score (Vtgm R2 score = 0.997, Vti R2 score = 0.999)로 TCAD simulation 결과값에 수렴한다는 것을 알 수 있다. 또한 SHapley Additive exPlanations (SHAP) value를 통해 input parameter의 중요도를 평가한 결과 Ycut과 Xseed parameter가 전기적 특성 변동에 가장 많은 영향을 준 것을 확인했다. 3D Vertical Silicon-Oxide-Nitride-Oxide-Silicon (SONOS) NAND was developed as a solution to the scaling down of planar-type NAND Flash memory. With 3D Vertical SONOS NAND, it is possible to stack many transistors on a limited-size wafer to secure more memory capacity than the planar type. However, with the change to the vertical structure, the cost of the process has increased along with the increase in process difficulty. Therefore, there is a need for a technology that reduces the process's cost and predicts the device's electrical characteristics quickly and accurately. In this paper, we used TCAD simulation and deep learning to predict and analyze the variation of electrical characteristics (Vtgm and Vti) of 3D Vertical SONOS NAND due to polysilicon grain boundary distribution (Max-angle, Ycut, Xseed, Yseed, Aseed) and geometrical variation (Width, Lcg). The electrical characteristics were predicted using deep learning trained based on TCAD simulation results and converged to TCAD simulation results with very high R2 scores (Vtgm R2 score = 0.997, Vti R2 score = 0.999). We also evaluated the importance of the input parameters through the SHapley Additive exPlanations (SHAP) value. We found that the Ycut and Xseed had the most influence on the variation of electrical characteristics.

      • KCI등재

        Development of a Li-Coated RPC for Low-Energy Neutron Detection

        이경세,심광숙,김병일,홍병식,김현철,김지현,이광복,Mikiko Ito,류민상,홍성종,안성환,박성근,강태임 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.48 No.4

        In this report, we present a newly developed hybrid resistive plate chamber (RPC) for the detection of low-energy neutrons. Lithium-°uoride (LiF) enriched for the 6Li isotope was chosen as the material sensitive to low-energy neutrons for the construction of the hybrid RPC. The LiF-coated RPC was tested by using the 252Cf neutron-irradiation facility at the Korea Atomic Energy Research Institute (KAERI). The detection e±ciency of the double-layered LiF-coated RPC to neutrons in the energy range from 10 to 560 meV was approximately 1.6 %. We obtained reliable e±ciency plateaus over a wide range of electric-.eld intensities.

      • KCI등재

        돼지생식기호흡기증후군바이러스 ORF7 유전자 발현 및 단크론항체 생산

        이승철 ( Seung Chul Lee ),박가혜 ( Ga Hye Park ),이경원 ( Kyeong Won Lee ),류민상 ( Min Sang Ryu ),강신영 ( Shien Young Kang ) 한국동물위생학회 2014 한국동물위생학회지 (KOJVS) Vol.37 No.3

        Porcine reproductive and respiratory syndrome virus (PRRSV) is the etiological agent of PRRS characterized by reproductive losses in sows and respiratory disorders in piglets. The PRRSV is a small enveloped virus containing a positive-sense, single-stranded RNA genome and divided into two genotype, type 1 (European) and type 2 (North American), respectively, by nucleotide identity. In this study, ORF7 gene of the type 1 and type 2 PRRSV was cloned and expressed in Baculovirus expression system. Also, monoclonal antibodies (MAbs) against ORF7 were produced and characterized. The expressed ORF7 proteins in the recombinant virus were confirmed by indirect fluorescence antibody (IFA) test using His6 and PRRSV-specific antiserum. A total of eight MAbs were produced and characterized. One (3G12) MAb was type 1 PRRSV ORF7-specific and two (6B10 and 16H8) were type 2 PRRSV ORF7-specific. Other five (1A1, 2A4, 4B4, 12C4 and 13F11) MAbs reacted with both type 1 and type 2 PRRSV. Some PRRSV ORF7-specific MAbs recognized the porcine tissues infected with PRRSV by IFA or immunohistochemistry (IHC) assay. From this experiment, it was confirmed that MAbs produced in this study were PRRSV ORF7-specific and could be used as reliable reagents for type 1/type 2 PRRSV detection.

      • KCI등재

        Construction and Performance Test of Prototype Parallel Plate Avalanche Counters at RAON

        Charles Akers,이광복,김영진,김은희,권영관,이효상,문전영,박진형,류민상,신택수,Satou Yoshiteru 한국물리학회 2017 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.70 No.7

        Two prototype position sensitive parallel plate avalanche counters (PPACs) have been fabricated at the Rare Isotope Science Project (RISP). Both detectors have active areas of 10 × 10 cm2 and utilize a stripped electrode structure, together with a delay line readout, to extract position information. Testing was conducted with an 241Am source, and 2-dimensional position information was obtained. A position resolution of 0.55 mm full width at half maximum (FWHM), together with a position linearity of ±55 μm over a 67-mm detection range, were measured. A time resolution of 450 ps (FWHM) was also measured.

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