돼지 적출 신동맥에 대한 adenosine triphosphate의 영향과 Ca⁺⁺의 동원

남윤정,김주헌,Nam, Yun-jeong,Kim, Joo-heon 대한수의학회 1991 大韓獸醫學會誌 Vol.31 No.3

The aims of this study were to investigate the effect of adenosine triphosphate (ATP), which has been known as the neurotransmitter of nonadrenergic, noncholinergic nerves, and the source of $Ca^{\sharp}$ in the effect of ATP on the isolated renal artery of pig. The results of this study were summarized as follows: 1. ATP caused the contraction and the contractile responses were increased in a dose-dependent manner between the concentration of ATP $2{\times}10^{-3}M$ and $10^{-2}M$ on the isolated renal artery of pig. 2. The contractile responses induced by ATP $(5{\times}10^{-3}M)$ were not blocked by pretreatment with cholinergic receptor blocker (atropine, $10^{-6}M$), $\alpha$-adrenergic recptor blocker(phentolamine, $10^{-6}M$) or $\beta$-adrenergic receptor blocker (propranolol, $10^{-6}M$), and $H_1$-receptor blocker (pyrilamine, $10^{-6}M$) or $H_2$-receptor blocker (cimetidine, $10^{-6}M$) on the isolated renal artery of pig. 3. The contractile responses induced by ATP $(5{\times}10^{-3}M)$ were not appeared in $Ca^{\sharp}$-free medium. As the concentration of $Ca^{\sharp}$ in $Ca^{\sharp}$-free medium was increased, the contractile responses induced by ATP $(5{\times}10^{-3}M)$ were enhanced but were completely inhibited by pretreatment with $Ca^{\sharp}$-channel blocker, papaverine $(5{\times}10^{-5}M)$ or verapamil $(5{\times}10^{-5}M)$ on the isolated renal artery of pig.

췌장후부에서 발생한 후복막강 점액 낭샘종 1예 (초)

남윤정,이재영,송재이,구민근,박준석,김경옥,이시형,장병익,김태년 대한내과학회 2012 대한내과학회 추계학술대회 Vol.2012 No.1

신장 허혈이 토끼 신기능과 lysine 및 alanine 배설에 미치는 영향

남윤정,김용근,김주헌,Nam, Yun-jeong,Kim, Yong-keun,Kim, Joo-heon 대한수의학회 1995 大韓獸醫學會誌 Vol.35 No.4

This study was carried out to determine the effect of renal ischemia on renal function and excretion of amino acid in rabbit. The animal models of renal ischemia induced experimentally by clamping the renal artery for different lengths of time. These results were summarized as follows: 1. Ischemia for 30 or 60 min produced a polyuria which is accompanied by an increase in $Na^+$ excretion. Glomerular filtration rate (GFR) and p-aminohippurate plasma($C_{PAH}$) were not altered by 30 min of ischemia, indicating that transient ischemia results in a marked tubular dysfuction before a reduction in GFR or renal blood flow. 2. Reabsorption of glucose and amino acids such as alanine and lysine was markedly reduced after 30 min of ischemia, and the effect was more pronounced after 60 min of ischemia.

Co-Occurrence of Papillary Thyroid Carcinoma and Mucosa-Associated Lymphoid Tissue Lymphoma in a Patient with Long-Standing Hashimoto Thyroiditis

남윤정,김보현,이승근,전윤경,김상수,정우진,강동환,김인주 대한내분비학회 2013 Endocrinology and metabolism Vol.28 No.4

Papillary thyroid carcinoma (PTC) is a common affliction of the thyroid gland, accounting for 70% to 80% of all thyroid cancers,whereas mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid gland is uncommon. The simultaneous occurrence of both malignancies is extremely rare. We report the case of a patient with both PTC and MALT lymphoma in the setting of Hashimoto thyroiditis. An 81-year-old female patient was first admitted with goiter and hoarseness, which was attributed to an ultrasonographic thyroid nodule. Subsequent fine-needle aspirate, interpreted as suspicious of papillary thyroid cancer, prompted total thyroidectomy. MALT lymphoma was an incidental postsurgical finding, coexisting with PTC in the setting of Hashimoto thyroiditis. Although the development of MALT lymphoma is very rare, patients with longstanding Hashimoto thyroiditis should undergo careful surveillance for both malignancies.

Homogeneous 에미터와 Selective 에미터 결정질 실리콘 태양전지의 온도에 따른 전류-전압 특성 변화 측정 및 분석

남윤정,박효민,이지은,김수민,김영도,박성은,강윤묵,이해석,김동환,Nam, Yoon Chung,Park, Hyomin,Lee, Ji Eun,Kim, Soo Min,Kim, Young Do,Park, Sungeun,Kang, Yoonmook,Lee, Hae-Seok,Kim, Donghwan 한국재료학회 2014 한국재료학회지 Vol.24 No.7

Solar cells exhibit different power outputs in different climates. In this study, the temperature dependence of open-circuit voltage(V-oc), short-circuit current(I-sc), fill factor(FF) and the efficiency of screen-printed single-crystal silicon solar cells were studied. One group was fabricated with homogeneously-doped emitters and another group was fabricated with selectively-doped emitters. While varying the temperature (25, 40, 60 and $80^{\circ}C$), the current-voltage characteristics of the cells were measured and the leakage currents extracted from the current-voltage curve. As the temperature increased, both the homogeneously-doped and selectively-doped emitters showed a slight increase in I-sc and a rapid degradation of V-oc. The FF and efficiency also decreased as temperature increased in both groups. The temperature coefficient for each factor was calculated. From the current-voltage curve, we found that the main cause of V-oc degradation was an increase in the intrinsic carrier concentration. The temperature coefficients of the two groups were compared, leading to the idea that structural effects could also affect the temperature dependence of current-voltage characteristics.

Herpes Simplex Virus Type-1 (HSV-1) 감염에 따른 세포내 유리 $Ca^{2+}$농도의 변화

남윤정,이규철,이찬희 한국미생물학회 2000 미생물학회지 Vol.36 No.4

Herpes simplex virus type-1 (HSV-1)의 감염에 따른 세포내 유리 칼슘농도의 변화에 대한 실험을 수행한 결과, HSV-1이 Vero 세포에 감염한 후 4시간째에 세포내 칼슘농도가 최대로 감소한 것을 알았으며 이러한 세포내 유리 칼슘농도의 감소는 감염성 바이러스의 양에 따라 커지며, 유전자 발현 억제제의 처리나 바이러스의 불활성화에 의해 극복되었다. 따라서 바이러스의 유전자발현이 세포내 유리 칼슘농도의 감소에 중요한 역할을 한다는 것을 알 수 있다. 또한 Vero 세포에 바이러스를 감염시키고 미세소관 안정제인 taxol을 처리하여 4 시간째의 세포내 유리 칼슘농도의 감소가 극복된다는 사실로부터 바이러스이 유전자 물질의 이동에는 미세소관이 관여한다는 것을 알 수 있었다. 이와 같은 실험 결과로부터 Vero 세포에서 HSV-1에 의해 유도되는 세포내 유리칼슘 농도의 감소는 HSV-1 증식과 밀접한 관계를 가진다고 생각된다. Infection of Vero cells with herpes simplex virus type-1 (HSV-1) resulted in a series of changes in intra-cellular free calcium concentration $([Ca^{2+}]_i)$. A significant and maximal decrease $[Ca^{2+}]_i$ was observed at 4 hours postinfection (hr p.i.) in HSV-1-infected in Vero cells. Inactivation of HSV-1 with UV irradiation and heat treatment abolished HSV-1-induced decrease in $[Ca^{2+}]_i$ at 4 hr p.i. in Vero cells. And the degree of the decrease in $[Ca^{2+}]_i$ was dependent on the amount of input virus. Taxol, which stabilizes the polymerization of microtubule blocked HSV-1-induced decrease in $[Ca^{2+}]_i$ at 4 hr p.i., suggesting that microtubule may mediate the transport of HSV-1 nucleocapsid to the nucleus of infected cell. Treatment of HSV-1-infected Vero cells with metabolic inhibitors such as cycloheximide, cordycepin, or acyclovir partially reversed the decrease in $[Ca^{2+}]_i$ at 4 hr p.i.. Thus, it is suggested that HSV-1 induced decrease in $[Ca^{2+}]_i$ at 4 hr p.i. in Vero cells may play an important role in the multiplication of HSV-1.

[정보 품앗이] 사물의 어제와 오늘 화장지를 돈 주고 산다고?

남윤정 샘터사 2005 월간 샘터 Vol.419 No.-

Computed Tomographic Features of Plate-Like Atelectasis in Four Dogs

남윤정,이영원,최호정 한국임상수의학회 2020 한국임상수의학회지 Vol.37 No.6

Four dogs were incidentally diagnosed as plate-like atelectasis (PLA) by thoracic radiographs. The dogs underwent thoracic computed tomography (CT) examination with various causes. On the lateral radiographs, PLA lesions were observed as a single linear or curvilinear radiopaque area in all four dogs. Although PLA lesions were observed linear structures on dorsal and sagittal reformatted CT images as in the radiographs, it appeared pulmonary opacification or band shape on transverse images. Therefore, care should be taken to differentiate PLA from other pulmonary diseases.

신장 허혈이 토끼 신피질 절편에서 아미노산 이동에 미치는 영향

남윤정,김주헌,Nam, Yun-jeong,Kim, Joo-heon 대한수의학회 1997 大韓獸醫學會誌 Vol.37 No.1

This study was carried out determine the effect of renal ischemia on amino acid transport in rabbit renal cortical slices. The animal models of renal ischemia induced experimentally by clamping the renal artery. These results were summarized as follows: 1. The uptake of amino acids lysine and ${\alpha}$-aminobutyrate(AIB), dicarboxylate succinate and organic anion PAH in cortical slices was normal or increased after 30 or 60 min of ischemia in vivo. 2. In a 30 min ischemic kidney, the slice uptake of amino acids was returned to the control level by 30 min of reflow. In a 60 or 90 min ischemic kidney, the lysine uptake was returned to the control level after of reflow, but the uptake of AIB and succinate was significantly reduced during reflow period of 30-120 min. 3. Oxygen consumption in cortical slices was increased after 30 min of ischemia but was not altered by 60 min of ischemia. This results indicat that transient ischemia caused increasing of amino acid uptake in renal cortical slices without metabolic disorder of renal proximal tubule.

ADHD아동의 읽기 이해점검능력

남윤정,황민아,임종아 한국학습장애학회 2012 학습장애연구 Vol.9 No.2

This study investigated reading comprehension monitoring skill in children with Attention Deficit Hyperactivity Disorder(ADHD). Twelve children with ADHD and twelve IQ and age-matched typically developing children participated in this study. All children were first to second grader in elementary schools. For the reading comprehension monitoring task, the children read two stories that contained ten false statements or inconsistencies. And then, they were asked to detect these erroneous sentences and to correct of inconsistences. The result showed that the total number of correct responses was significantly lower in children with ADHD relative to the peers. These results suggested that children with ADHD appeared to experience difficulty in reading comprehension monitoring when they read a complicated and long text. 본 연구는 초등학교 1~2학년 ADHD아동 12명을 대상으로 ADHD아동의 읽기 이해점검능력을 일반아동과 비교하여 조사하였다. 아동들은 각각 5개의 불일치한 내용이 삽입된 2개의 이야기를 읽으면서 불일치 문장을 찾고 오류를 설명하는 과제를 수행하였다. 불일치한 내용을 잘 탐지하고 수정한 경우 1점을 주어 총 10점 만점이 되게 채점하여 독립표본 t 검정을 실시한 결과, ADHD아동의 읽기 이해점검능력이 일반아동에 비해 유의미하게 저조하였다. 하지만 불일치가 없는데도 과도하게 점검한 오류빈도에는 유의미한 차이가 나타나지 않았다. 이러한 결과는 ADHD아동이 기본적인 읽기능력에 어려움이 없음에도 불구하고 길고 복잡한 읽기과제에서는 자신의 이해정도를 인식하고 평가하여 효율적인 읽기 수행을 이루어내는데 어려움을 경험할 가능성이 있음을 의미한다.