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      • 효율적 선석운영을 위한 의사결정지원시스템에 관한 연구

        김동희,허동은,김봉선,이창호,Kim, Dong-Hee,Huh, Dong-Eun,Kim, Bong-Sun,Lee, Chang-Ho 대한산업공학회 1998 산업공학 Vol.11 No.1

        In these days many people have studied on the berthing problem. The operation rules differ from port so port and the problem is highly dependent on the environment of port. The purpose of this study is to develop a decision support system decision makers of the berthing problem for Inchon Port. The system is developed with graphic user interface(GUI) using user-interactive approach and some general and specific rules for Inchon Prot are considered. The system is composed of the following four parts ; the input/output part, the automatic berthing part by the system using rules, the manual berthing part by user, and the part for modifying results or handling exceptional events. The system is designed to assign ship to berths by matching the characteristics with environmental and operational constraints of Inchon Port. We expect that this system can provide decision makers with an efficient and fast way to berthing and can reduce wastes of time, space, and manpower in port operations.

      • 염기서열 특이적 전사종결에 영향을 주는 T7 파아지 lysozyme의 역할

        김동희,이상수,Kim, Dong-Hee,Lee, Sang-Soo 배재대학교 자연과학연구소 2004 自然科學論文集 Vol.14 No.1

        박테리오 파아지 T7 RNA 중합효소는 어떤 전사인자도 관여하지 않는 간단한 시스템으로 파아지 RNA 중합효소와 전사촉진제만의 단백질-DNA 상호작용에 의해 전사가 진행된다. T7 파아지의 숙주 세포의 파괴에 관여하는 T7 파아지 lysozyme은 전사를 억제하고, 전사종결에 영향을 미친다. 따라서 T7 파아지 lysozyme 유전자를 대장균 발현 벡터에 삽입하여 pT7lys를 얻었고, 발현시켜 Ni-NTA column chromatography로 순수 분리하였다. T7 파아지 lysozyme은 SDS-gel에서 단일 밴드로 확인하였으며, amidase 활성 역시 확인하였다. 염기서열 특이적 전사 종결에 미치는 T7 파아지 lysozyme의 역할을 알아보기 위하여, rrnB T1 전사종결 인자 부근에서의 전사연장 복합체 제조에 미치는 T7 파아지 lysozyme의 영향력을 조사하였다. 이 결과 T7 파아지 lysozyme 존재 하에 형성되는 전사연장 복합체는 불안정함을 알 수 있었다. T7 RNA polymerase is a single subunit RNA polymerase able to accomplish whole transcription process without auxiliary factors. T7 phage lysozyme involcing in destruction of host cell wall repress T7 transcription and affects transcription termination process. Therefore expression vector pT7lys containing T7 phage lysozyme gene was constructed and expressed. T7 phage lysozyme protein was purified to homogeneity by Ni-NTA column chromatography. Also amidase activity of the purified lysozyme was identified. In order to understand the effect of the lysozyme on the sequence specific transcription termination. T7 transcription elongation complexes at the site rrnB T1 transcription termination signal were made in the presence the lysozyme. The results shows that the transcription elongation complexes are unstable in the presence of T7 phage lysozyme.

      • KCI등재

        모의실험을 통한 인천항의 운영실태분석에 관한 연구

        김동희,최운,김봉선,이창호,Kim, Dong-Hee,Choi, Un,Kim, Bong-Sun,Lee, Chang-Ho 한국산업경영시스템학회 1999 한국산업경영시스템학회지 Vol.22 No.49

        The purpose of this study is to develop a port simulation program for Inchon Port. The arrival and departure data from Inchon Port is analyzed and the berthing rule based on formal materials and experiences is constructed. A Port-Simulation program to analyze the effects of the changes in ship arrivals, service capacities upon the demurrage is constructed and several scenarios are analyzed. It is expected that we can use the simulation results in order to prepare proper service levels and plan appropriate investment strategies.

      • KCI등재

        급속열처리를 통한 알루미나 나노 템플레이트의 기공 균일도 개선에 관한 연구

        김동희,김진광,권오대,양계준,이재형,임동건,Kim Dong-Hee,Kim Jin-Kwang,Kwon O-Dae,Yang Kea-Joon,Lee Jae-Heong,Lim Dong-Gun 한국전기전자재료학회 2006 전기전자재료학회논문지 Vol.19 No.2

        Ordered nanostructure materials have received attention due to their unique physical properties and potential applications in electronics, mechanics and optical devices. To actualize most of the proposed applications, it is quite important to obtain highly ordered nanostructure arrays. The well-aligned nanostructure can be achieved by synthesizing nanostructure material in the highly ordered template. To get well-aligned pore array and reduce process time, rapid thermal anneal by an IR lamp was employed in vacuum state at $500^{\circ}C$ for 2 hour. The pore array is comparable to a template annealed in vacuum furnace at $500^{\circ}C$ for 30 hours. The well-fabricated AAO template has the mean pore diameter of 70 nm, the barrier layer thickness of 25 nm, the pore depth of $9{\mu}m$, and the pore density of higher than $1.2{\times}10^{10}cm^{-2}$.

      • KCI등재후보

        양측 제 1,4 단중족증의 자가골을 이용한 일단계 골연장술(1예 보고)

        김동희,정덕환,한정수,이재훈,박재용,오경일,탁대현,Kim, Dong-Hee,Chung, Duke-Whan,Han, Chung-Soo,Lee, Jae-Hoon,Park, Jae-Yong,Oh, Kyung-Il,Tak, Dae-Hyun 대한족부족관절학회 2010 대한족부족관절학회지 Vol.14 No.2

        19 years old girl presented with bilateral 1, 4th brachymetatarsia. We have used an autograft interposition technique to lengthen the brachymetatarsia involving first and fourth metatarsal. The technique was to graft the bone fragment from the relatively long second and third metatarsal bone to be used as an autograft to the short first and fourth metatarsal bone. The method is superior in not having the necessity of a long term external fixator which is needed using callotasis method and in also avoiding the inconvenience of performing an allograft. Absence of donor site complication during autograft from iliac bone is also an advantage to be mentioned. Our technique can therefore be ascertained as a successful method in both cosmetic results and improvement of symptoms including reduction in length of recovery.

      • KCI등재

        Idiopathic Hypertrophic Cranial Pachymeningitis Masquerading as Tolosa-Hunt Syndrome

        김동희,황윤수,이학승,박현영,Kim, Dong Hee,Hwang, Yun Su,Lee, Hak Seung,Park, Hyun Young The Korean Society of Clinical Neurophysiology 2016 Annals of Clinical Neurophysiology Vol.18 No.1

        Idiopathic hypertrophic cranial pachymeningitis (ICHP) is diffuse inflammatory process of the dura mater. ICHP can produce similar presentation with Tolosa-Hunt syndrome (THS) if it involves cavernous sinus. A-29-year old male with persistent headache and no definite neurologic dysfunction was noted. Two weeks later, he complained of ophthalmoplegia, and his symptoms were thought to be manifestations of THS. Brain magnetic resonance images revealed diffuse thickened, enhanced pachymeninges in left tentorium. The patient was diagnosed with IHCP. We report a IHCP patient who showed very similar presentation as THS.

      • KCI등재

        동의보감에 수재된 오계(烏鷄)에 대한 생리활성 연구

        김진우 ( Jin Woo Kim ),심부용 ( Boo Yong Sim ),최학주 ( Hak Joo Choi ),이해진 ( Hea Jin Lee ),김동희 ( Dong Hee Kim ) 대한본초학회 2015 大韓本草學會誌 Vol.30 No.5

        Objectives: The aim of this study is to investigate cell viability, anti-inflammatory, antioxidant, immunoenhancing activity using various extracts of Yeonsan Ogye. Methods: In order to evaluate cytotoxicity, MTT assay was performed. We investigated production levels of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-6, and nitric oxide(NO) in LPS-induced RAW 264.7 cells. NO production in RAW 264.7 cells was measured by using Griess reagent. Cytokines including IL-6 and TNF-α were measured by Luminex and ROS was measured by Flow cytometry. Results: No cytotoxicity of various extracts of Yeonsan Ogye was observed in RAW 264.7 cells. Productions of ROS in RAW 264.7 cells were increased from extraction of bones and decreased from extraction of skin. Also, productions of NO in RAW 264.7 cells were increased to bone extract and decreased at skin extract. In addition, productions of pro-inflammatory cytokines (IL-6 and TNF-α) in LPS-induced RAW 264.7 cells were decreased at skin, meat extracts, respectively. Finally, the levels of immune-related cytokines (IL-6 and TNF-α) were increased compared to those of the normal group. Conclusions: It is concluded that Yeonsan Ogye extracts seem to have significant biological activities likes anti-inflammatory, antioxidant, immuno-enhancing etc. These results may be developed as a raw material for new health food and new therapeutics to ease the symptoms related with inflammatory and oxidative stress. In terms of oriental traditional medicine, we expect that it contribute to building of EBM (Evidence-Based Medicine) from the this result.

      • 부스트 컨버터 토폴로지의 스위칭 주파수에 따른 손실 분석

        김동희(Dong-Hee Kim),최규영(Gyu-Yeong Choe),이병국(Byoung-Kuk Lee),이태원(Tae-Won Lee) 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.11

        본 논문에서는 부스트 컨버터 토폴로지의 하드스위칭 기법과 소포트스위칭 기법의 주파수에 따른 손실을 분석한다. 이에 따라 스위칭 주파수에 따른 최소의 손실이 발생하는 토폴로지를 도출한다. 각각의 손실 분석은 실제 소자의 파라메터를 동일하게 적용하여 이론적으로 분석 한다.

      • KCI등재

        불면장애에 대한 혈부축어탕의 체계적 문헌 고찰 및 메타분석 연구

        김동희 ( Dong-hee Kim ),이승환 ( Seung-hwan Lee ),임정화 ( Jung-hwa Lim ),김상호 ( Sang-ho Kim ),이상협 ( Sang-hyup Lee ),김보경 ( Bo-kyung Kim ) 대한한방신경정신과학회 2017 동의신경정신과학회지 Vol.28 No.4

        Objectives: The present study aimed to provide clinical evidence on the effect of herbal medicine, Hyeolbuchukeo-tang or Xuefu Zhuyu decoction for the treatment of primary insomnia using a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: This study included RCTs that verified the effects of Hyeolbuchukeo-tang or Xuefu Zhuyu decoction for the treatment of primary insomnia. Literature searches of English, Chinese and Korean databases were performed, and the selected literature was assessed for investigating the risk of bias. Results: The analysis included 10 RCTs. The Chinese Classification of Mental Disorders-3 was most frequently used to define the diagnostic criteria for Hyeolbuchukeo-tang or Xuefu Zhuyu decoction intervention in patients with primary insomnia. The effective rate was the most commonly used outcome measure. A meta-analysis revealed that the effective rate, the Pittsburgh Sleep Quality Index, and the Athens Insomnia Scale in the Modified Xuefu Zhuyu decoction (MXZD) group were higher compared to Western Medicine (WM) group (RR: 1.17, 95% Cl: 1.08 to 1.26, p<0.0001, I<sup>2</sup>=0 / MD: -1.29, 95% Cl: -2.09 to -0.49, p=0.002, I<sup>2</sup>=0% / MD: -0.99, 95% Cl: -1.81 to -0.18, p=0.02, I<sup>2</sup>=15%). The effective rate of the MXZD+WM group was significantly different compared to the WM group (RR: 1.28, 95% Cl: 1.11 to 1.47, p=0.0006, I<sup>2</sup>=2%). The included RCTs were of relatively poor quality and had small sample sizes. Conclusions: Treatment with Hyeolbuchukeo-tang or Xuefu Zhuyu decoction was found to be effective in treating primary insomnia. However, the included RCTs were of relatively poor quality and had small sample sizes. It is hypothesized that this study could serve as a foundation for further clinical studies on the development of diagnosis and treatment methods for primary insomnia based on Korean medicine.

      • KCI등재

        역설계 기법을 사용한 도심항공 모빌리티용 복합형(틸트로터 + 양력 + 순항) eVTOL의 공력 해석, 요구 동력 및 중량 예측

        김동희 ( Dong-hee Kim ),이준희 ( Joon-hee Lee ),황호연 ( Ho-yon Hwang ) 한국항행학회 2021 韓國航行學會論文誌 Vol.25 No.1

        최근 많은 나라 대도시의 교통체증과 더불어 지구온난화로 인해 차세대 친환경 교통수단인 eVTOL이 각광받고 있다. 본 연구에서는 많은 유형의 eVTOL 중 고정로터와 틸트로터가 결합된 복합형 eVTOL인 현대자동차 S-A1의 외부형상을 벤치마킹하여 역설계 기법을 활용하여 기본 형상을 구현하였다. CATIA를 사용하여 기본 형상을 구현한 후 항공기 설계 및 공력해석 프로그램인 OpenVSP, XFLR5를 사용하여 공력해석을 수행하였고 비교분석을 통해 익형과 붙임각, 상/하반각을 선택한 후 항공기 표면적 및 항력, 양력을 계산하였다. 또한 주어진 임무형상을 수행하기 위한 필요 동력을 산정하고 추정식과 자료조사를 통하여 구성품과 전체 무게를 추정하였다. Recently, eVTOL, the next-generation of eco-friendly transportation, has been in the spotlight due to global warming along with traffic jams in large cities of many countries. This study benchmark the external features of Hyundai Motors S-A1, a compound eVTOL combined fixed and tilt rotors among many types of eVTOLs, to create the basic configuration using reverse design techniques. Basic configurations were created using CATIA and aerodynamic analyses were performed using the aircraft design and aerodynamic analysis programs, OpenVSP, XFLR5, and the aircraft wetted area, drag, and lift were calculated after selecting the airfoil, incidence angle, and dihedral and anhedral angles through trade study. Also, required powers were estimated for completing the given mission profile and components weight and the total weight were predicted using the estimation formula and data survey.

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