선형탄성파괴역학을 이용한 5Ni - Cr - Mo - V 계 고인성 고장력강의 응력부식현상연구

김동규,김규영,권혁상,이성근,심인옥,김영우 ( Dong Kyou Kim,Kyoo Young Kim,Hyuk Sang Kwon,Sung Keun Lee,In Ok Sim,Young Woo Kim ) 한국부식방식학회 1995 Corrosion Science and Technology Vol.24 No.1

폴리에틸렌 글리콜의 공유부착에 의한 Adenosine Deaminase 의 성질변화에 관한 연구

김동규,김은진,강신원,김승원 ( Dong Kyoo Kim,eun Jin Kim,Shin Won Kang,Seung Won Kim ) 생화학분자생물학회 1993 BMB Reports Vol.26 No.1

The adenosine deaminase from calf intestinal mucosa was modified with 2,4-bis(o-methoxy-polyethylene glycol)-6-chloro-s-triazine(activated PEG), which was synthesized from monomethoxypolyethylene glycol(MW 5,000) and cyanuric chloride. Approximately 41 out of the total 69 amino groups in the adenosine deaminase molecule were modified. The conjugation of PEG increased affinity for adenosine showed by decreased K_m. ADA and PEG-ADA had temperature optima of 60℃ and 50℃, respectively. Thermal inactivation at temperature above optima was essentially the same for the native and modified enzyme. PEG-ADA and ADA demonstrated an resistance to proteolytic digestion of trypsin and chymotrypsin. Modification of the adenosine deaminase with PEG resulted in greatly decreased electrophoretic mobility of the protein. The modified ADA preparations were less immunogenic and antigenic than native enzyme as determined by immunodiffusion studies.

수정된 반복 주성분 분석 기법에 대한 연구

김동규,김아현,김현중,Kim, Dong-Gyu,Kim, Ah-Hyoun,Kim, Hyun-Joong 한국통계학회 2011 응용통계연구 Vol.24 No.5

다변량 자료를 분석함에 있어 자료의 차원을 축소하는데 활용되는 중요한 툴 중 하나인 PCA 분석(주성분 분석, Principal Component Analysis)을 실시간으로 처리해야 하는 적용 분야가 최근 늘고 있다. PCA 분석에서는 표본 공분산 행렬의 고유값과 고유벡터를 도출하는 것이 관건인데, 자료의 양이 방대하며 고차원인 경우 이를 실시간으로 수행하기에는 어려움이 따른다. 이러한 문제점을 해결하기 위해서 Erdogmus 등 (2004)는 일차 섭동 이론(first order perturbation theory)을 활용하여 공분산 행렬의 고유값과 고유벡터를 추정하는 Recursive PCA 방법을 제안했다. 이 방법은 추가된 자료의 양이 많지 않은 경우는 상당히 정확하지만, 추가된 자료의 양이 많아짐에 따라 오차도 커진다는 한계를 가지고 있다. 본 논문은 공분산 행렬의 고유값과 고유벡터가 가지고 있는 수학적 관계를 이용하여 Erdogmus 등 (2004)가 제안한 Recursive PCA 방법을 수정한 Modi ed Recursive PCA 방법을 제안하다. 또한, 모의 실험을 통해 Recursive PCA 방법과 Modi ed Recursive PCA 방법에서의 고유값과 고유벡터 추정값의 정확도를 비교해 보았으며 그 결과 기존 Recursive PCA 방법 보다 정확한 추정이 가능함을 확인할 수 있었다. PCA(Principal Component Analysis) is a well-studied statistical technique and an important tool for handling multivariate data. Although many algorithms exist for PCA, most of them are unsuitable for real time applications or high dimensional problems. Since it is desirable to avoid extensive matrix operations in such cases, alternative solutions are required to calculate the eigenvalues and eigenvectors of the sample covariance matrix. Erdogmus et al. (2004) proposed Recursive PCA(RPCA), which is a fast adaptive on-line solution for PCA, based on the first order perturbation theory. It facilitates the real-time implementation of PCA by recursively approximating updated eigenvalues and eigenvectors. However, the performance of the RPCA method becomes questionable as the size of newly-added data increases. In this paper, we modified the RPCA method by taking advantage of the mathematical relation of eigenvalues and eigenvectors of sample covariance matrix. We compared the performance of the proposed algorithm with that of RPCA, and found that the accuracy of the proposed method remarkably improved.

탄소섬유 및 탄소복합재의 물리적/기계적 특성에 대한 고온열처리의 영향 연구

김동규,하헌승,박인서,임연수,윤병일,Kim, Dong-Gyu,Ha, Heon-Seung,Park, In-Seo,Im, Yeon-Su,Yun, Byeong-Il 한국재료학회 1994 한국재료학회지 Vol.4 No.3

PAN계 탄소섬유 roving 및 fabric을 $2170^{\circ}C$에서 열처리 하였다. 열처리를 행하지 않은 탄소섬유 fabric과 행한 것을 사용하고, Autoclave를 이용하여, CFRP와 CFRP의 성형체를 제조하였다. 열처리를 행한 탄소섬유 roving과 행하지 않은것 및 두종류의 성형체의 분석을 통하여, 열처리에 따른 탄소섬유 및 탄소복합재의 물리적. 기계적 특성변화를 연구하였다. 열처리 후 성유의 단면을 주사전자현미경으로 관찰한 결과 탄소섬유의 직경이 6.8$\mu \textrm{m}$에서 6.4$\mu \textrm{m}$으로 감소하였으며, 열중량분석을 행한 결과 내산화성이 증진되었음을 알았다. 단섬유인장실험 결과 인장강도는 탄소섬유의 (3.11$\pm 0.32)\times 10^3$ MPa 에서 열처리 섬유의 (1.87$\pm 0.26)\times 10^3$MPa으로 감소되었으나, 탄성율은 탄소섬유의 (1.94$\pm 0.06)\times 10^5$ MPa에서 열처리 섬유의 (2.02$\pm 0.11)\times 10^5$MPa으로 증가하였다. 층간전단강도 측정 실험을 한 결과 그 값이 CFRP(148.8$\pm$1.6Mpa)가 CFRP(82.2$\pm$1.1Mpa)에 비하여 높음을 알 수 있었고, torch test 결과 CFRP는 층간분리 없이 매끄러운 삭마가 일어나나, GFRP는 층간분리가 발생함을 알 수 있었다. PAN-based carbon fiber roving and fabric were heat treated at the temperature of $2170^{\circ}C$. Using non-heat treated and heat treated fabric, greenbodies of CFRP and GFRP were manufactured in the Autoclave. After the analysis of heat treated and non-heat treated carbon fiber roving and two types of greenbodies, the variations of physical and mechanical properties of carbon fibers and greenbodies with heat treatment were studied. Observing the cross-section of carbon fiber with SEM, we knew the diameter of carbon fiber was decreased from 6.8gm to 6.4p1. The results of TGA showed that the oxidation resistence was enhanced after heat treatment. The tensile strength of carbon fiber was decreased from (3.11$\pm 0.32)\times 10^3$ MPa to (1.87$\pm 0.26)\times 10^3$MPa, but tensile modulus was increased from (1.94$\pm 0.06)\times 10^5$ MPa to (2.02$\pm 0.11)\times 10^5$MPa after heat treatment. The interlaminar shear strengths of CFRP and GFRP were 148.8$\pm$1.6Mpa and 82.2$\pm$1.1Mpa, respectively. Torch test showed that CFRP was abraded smoothly but GFRP was delaminated.

굴곡측정법을 이용한 극후판 용접부 잔류응력분포 정량분석

김동규,우완측,강윤희,Kim, Dong-Kyu,Woo, Wanchuck,Kang, Youn-Hee 대한용접접합학회 2015 대한용접·접합학회지 Vol.33 No.1

Residual stresses arising from the materials processing such as welding and joining affect significantly the structural integrity depending on the external loading condition. The quantitative measurement of the residual stresses is of great importance in order to characterize the effects of the residual stresses on the structural safety. In this paper, we introduce a newly devised destructive technique, the contour method (CM), which is applied for the measurements of the residual stress distributions through the thickness of a 80 mm thick steel weld. Residual stresses are evaluated from the contour, which is the normal displacement on a cut surface produced by the relaxation of residual stresses, using a finite element model. The CM provides a two-dimensional map of the residual stresses normal to the cut surface. The CM developed in the present study was validated in comparison with the residual stress distribution determined by a well-established neutron-diffraction residual stress instrument (RSI) instrumented in HANARO neutron research reactor.

Enhanced Type 2 Immune Reactions by Increased IL-22/IL-22Ra1 Signaling in Chronic Rhinosinusitis With Nasal Polyps

김동규,Ara Jo,Hee-Suk Lim,김진엽,Kyoung Mi Eun,Jayoung Oh,Joon Kon Kim,Seong-Ho Cho,김대우 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.6

Purpose: Recent studies have revealed the pathogenic role of interleukin (IL)-22 in atopic dermatitis and asthma. However, little is known about the role of IL-22 in the pathophysiology of chronic rhinosinusitis with nasal polyps. We aimed to investigate the expression of IL-22 and its pathogenic function in type 2 immune reactions of nasal polyps (NP). Methods: Protein levels of inflammatory mediators were determined by multiplex immunoassay, and principal component analysis (PCA) was performed. Immunofluorescence analysis and mast cell culture were used to determine the cellular sources of IL-22. Normal human bronchial epithelial (NHBE) cells were stimulated using IL-22 in combination with diverse cytokines, and thymic stromal lymphopoietin (TSLP) was measured. Results: IL-22 expression was not up-regulated in NP compared with control tissues, but IL-22-high NP revealed distinct features characterized by type 2 inflammatory cytokines such as chemokine (C-C motif) ligand (CCL)-11, CCL-24, and IL-5 on the PCA. Additionally, IL-22 positively correlated with type 2 immune mediators and the disease severity in NP. For the localization of the cellular sources of IL-22 in eosinophilic NP, it was expressed in cells mostly composed of eosinophil peroxidase-positive cells and partially of tryptase-positive cells. The human mast cell line, LAD2 cells, released IL-22 mediated by immunoglobulin E. Moreover, IL-22 receptor subunit alpha-1 (IL-22Ra1) expression was significantly increased in NP. IL-22Ra1 was up-regulated with poly(I:C) stimulation in NHBE cells. Furthermore, TSLP production was enhanced when stimulated with a combination of IL-13, poly(I:C), and IL-22. Treatment with anti-IL-22Ra1 also inhibited IL-22-induced enhancement of TSLP production. Conclusion: IL-22 was associated with type 2 inflammatory reactions in NP. The IL-22/IL-22Ra1 axis was enhanced and might be involved in type 2 inflammatory reactions via TSLP production in NP.

유무기 TiO₂-SiO₂ 혼성코팅에 미치는 전구체 배합비율의 영향

김동규,맹완영,Kim, Dong Kyu,Maeng, Wan Young 한국재료학회 2016 한국재료학회지 Vol.26 No.5

When a single inorganic precursor is used for the synthesis of a sol-gel coating, there is a problem of cracking on the surface of coating layer. In order to solve this problem of surface cracking, we synthesized inorganic-organic coatings that have hybrid properties of inorganic and organic materials. Sols of various ratios (1:0.07, 0.2, 0.41, 0.82, 1.64, 3.26, 6.54, 13.2) of an inorganic precursor of Tetrabutylorthotitanate ($Ti(OBu)_4$, TBOT) and an organic precursor of ${\gamma}$-Methacryloxy propyltrimethoxysilane (MAPTS) were prepared and coated on stainless steels (SUS316L) by dip coating method. The binding structure and the physical properties of the synthesized coatings were analyzed by FT-IR, FE-SEM, FIB (Focused Ion Beam), and a nano-indenter. Dynamic polarization testing and EIS (electrical impedance spectroscopy) were carried out to evaluate the micro-defects and the corrosion properties of the coatings. The prepared coatings show hybrid properties of inorganic oxides and organic materials. Crack free coatings were prepared when the MAPTS ratio was above a critical value. As the MAPTS ratio increased, the thickness and the corrosion resistance increased, and the hardness decreased.

A histochemical study of the oxytalan fibers in periodontium of rats during experimental tooth movement

김동규,Kim, Dong-Kyu The Korean Academy of Prosthodonitics 1968 대한치과보철학회지 Vol.8 No.1

1958년(年) Fullmer와 $Lillie^9$에 의(依)하여 최초(最初)로 보고(報告)된 Oxytalan 섬유(纖維)는 산(酸)에 내성(耐性)이 강(强)한 섬유(纖維)로 치근막(齒根膜)에 많이 출현(出現)하고 기계적(機械的) 자극(刺戟)에 의(依)하여 배열(配列), 주행(走行) 및 수적(數的)인 변화(變化)를 가져온다. 저자(著者)는 교정력(矯正力)을 이용(利用)하여 치아(齒牙)를 이동(移動) 시킨후(後) 치근막내(齒根膜內) Oxytalan섬유(纖維)의 수(數), 주행(走行) 및 형태(形態)의 변화(變化)를 실험적(實驗的)으로 관찰(觀察)한바 있어 이를 보고(報告)하는 바이다. 본연구(本硏究)에 사용(使用)된 실험동물(實驗動物)로는 체중(體重) 60gram내외(內外)의 자성백서(雌性白鼠) 15마리를 택(澤)하였다. 각동물(各動物)은 Ether마취후(麻醉後) 교정용(矯正用) 고무줄편(片)을 상악우측(上顎右側) 제1구치(第一臼齒)와 제2구치(第二臼齒) 사이에 삽입(揷入)하여 24, 48, 72시간(時間) 간격(間隔)으로 관찰(觀察)하였다. 동물(動物)을 도살후(屠殺後) 상악골(上顎骨)을 적출(摘出)하여 10%중성(中性) 호루마린에 고정후(固定後) 3%의산(蟻酸)으로 탈회(脫灰)하였다. 파라핀 포매후(包埋後) 근원심적(近遠心的)으로 $4{\sim}6{\mu}$의 절편(切片)을 만들어 Hematoxylin-eosin 및 Aldehyde fuchsin염색(染色)을 시행(施行)하여 경험(鏡險)한 결과(結果)는 하기(下記)와 같다. 1. 치아이동후(齒牙移動後) 교원성섬유(膠原性纖維) 및 Oxytalan섬유(纖維)들의 배열(配列)에 있어 뚜렷한 차이(差異)를 보였다. 2. 치아이동후(齒牙移動後) 사주섬유(斜走纖維)는 염박측(壓迫側)에서는 치아장축(齒牙長軸)에 수직(垂直)되게, 견인측(牽引側)에서는 평행(平行)되게 주행(走行)하고 있었다. 3. 48시간군(時間群)에서 세포증식(細胞增殖)이 심(甚)하였다. 4. Oxytalan섬유(纖維)는 치아(齒牙)들에 교정력(矯正力)을 가(加)한후(後) 견인(牽引) 염박(壓迫) 양측(兩側) 공(共)히 수(數)가 증가(增加)하였다. 5. 염박측(壓迫側)에서 Oxytalan섬유(纖維)는 속(束)을 형성(形成)하며 치아장축(齒牙長軸)에 평행(平行)되게 주행(走行)하였다. 6.견인측(牽引側)에서는 하나 또는 두세개의 섬유(纖維)들이 산발적(散發的)으로 치아장축(齒牙長軸)에 평행(平行)되게 하였다. 7. Oxytalan섬유(纖維)의 수(數)는 염박측(壓迫側)에서 보다 견인측(牽引側)에서 더 변화(變化)가 많았다.

부분구조합성법을 이용한 컴프레서 쉘의 동특성 규명 및 개선에 관한 연구

김동규,김종배,고상철,한광희,오재응,Kim, Dong-Kyu,Kim, Jong-Bae,Go, Sang-Chul,Han, Kwang-Hee,Oh, Jae-Eung 한국음향학회 1996 韓國音響學會誌 Vol.15 No.5

컴프레서의 소음은 냉장고로부터 발생하는 전체 소음레벨중 높은 기여를 나타낸다. 그리고, 컴프레서로부터 방사되는 소음의 상당부분이 컴프레서 쉘의 진동에 의해 방사되는 소음이다. 본 연구에서는 컴프레서 쉘의 동특성을 규명하기 위하여 범용 구조해석 패키지인 MSC/NASTRAN을 이용하여 컴프레서 쉘을 여러 분계로 분리하여 해석한 뒤, 부분구조 합성법을 이용하여 전계의 동특성을 규명하였다. 그리고 각 분계의 변형 에너지와 운동에너지를 산정하여 각 분계가 전계에 기여하는 정도를 파악하였다. 컴프레서 소음에 가장 높은 영향을 미치는 1차모드를 고주파로 이동시키기 위하여, 1차 모드에 기여가 높은 분계의 질량과 강성을 변경하여 컴프레서 쉘의 동특성 개선 방향을 제시하였다. The noise of a compressor is a major contributor to overall noise radiated from the refrigerator. The major source of the noise is radiated by the vibration of the compressor shell. In this study, to identify the dynamic characteristics of compressor shell, a compressor shell is divided into several components and these are analyzed with a commercial FEM(Finite Element Method) package such as MSC/NASTRAN. Using substructure synthesis method, the dynamic characteristics of the total system is identified. The coherence of each component to the total system is computed by using strain and kinetic energy. To increase the frequency of the first resonance mode which is most effective mode to the noise of the compressor shell, the improving strategy of dynamic characteristics is suggested by changing mass and stiffness of the coherence component to the first mode.

고유동 흙막이 벽체 재료의 역학적 성능 및 내구성에 대한 강섬유 혼입률의 영향

김동규,이승태,Donggyu Kim,Seungtae Lee 한국지반환경공학회 2023 한국지반환경공학회논문집 Vol.24 No.6

This paper is aimed to evaluate the mechanical properties and durability of high-flowable retaining wall material (RWM) with different levels of steel fiber (SF) content. To produce the specimens of RWM, some chemical agents such as superplasticizer (SP), air-entrained agent (AEA) and viscosity modifying agent (VMA) were added in the fresh RWM. The compressive and split tensile strength measurements were performed on the hardened RWM specimens at the predetermined periods. Additionally, surface electric resistivity and absorption tests according to ASTM standards were carried out to examine mechanical properties of RWM mixes. The durable performances such as chloride ions penetrability and freezing-thawing resistance of RWM mixes were experimentally investigated. As resutls, it was found that the performance of RWM mix with SF were much better than that without SF, especially at the 2% addition of SF. Thus, it is noted that the proper addition of SF in the RWM mix may have a beneficial effect to improve mechanical properties and durability of RWM mixes.