편측안면경련에서 미세혈관감압술의 성적

곽형준,김재휴,이정길,김태선,정신,김수한,강삼석,이제혁,Kwak, Hyoung Jun,Kim, Jae Hyoo,Lee, Jung Kil,Kim, Tae Sun,Jung, Shin,Kim, Soo Han,Kang, Sam Suk,Lee, Je Hyuk 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.4

Objectives : Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement on one side of face. It is known that hemifacial spasm is mainly due to pulsatile compression by vessels at the root exit zone(REZ) of the facial nerve. Microvascular decompression at REZ of the facial nerve has become the standard treatment modality for hemifacial spasm. The authors have analized patients with hemifacial spasm treated with microvascular decompression to evaluate operation result and clinical course after operation. Patients and Methods : From 1992 to 1999, 41 patients with hemifacial spasm underwent this operation. Retrospective analysis of operation results and clinical recovery patterns was done. The length of observation had been more than 6 months in all cases. Results : The ratio of male to female was 1:1.4, and age at operation ranged from 24 to 66 years. Their mean age was 47.6 years and the mean preoperative duration of symptoms was 7.2 years. Most common offending vessels were AICA in 18 cases(48%) and second most common were PICA in 13 cases(31.7%). The rest of them were 3 case in vertebral artery, and 7 cases(13%) in multiple offending vessels. Patterns of improvement after surgery could be divided into 4 clinical types. There was complete recovery in 3 days after operation in 24 cases(58.6%, Immediate complete recovery). There was complete recovery in 3 days after operation, and symptom was recurred partially, which was gradually subsided in 2 weeks after operation in 4 cases(9.8%, Delayed complete recovery type I). There was partial recovery after operation and symptom was compretely disappeared gradually in 6 months after operation in 7 cases(17.1%, Delayed complete recovery type II). Finally, there was partial recovery after operation, and symptom was somewhat remained after 6 months later(14.5%, Delayed partial recovery). Conclusion : In conclusion, microvascular decompression for hemifacial spasm is a safe and reliable treatment modality with good results of improvement and there are 4 recovery patterns in clinical course after operation in our series. Therefore, follow-up observation after microvascular decompression is necessary to evaluate the operative results and complication, especially in the delayed resolved cases.

에멀젼형 절삭유 수용액내 침지식 정밀여과막의 SFCO 투과 파형에 따른 막간차압

곽형준,이현우,원인혜,정건용 한국막학회 2015 한국막학회 총회 및 학술발표회 Vol.2015 No.05

본 연구에서는 침지형 정밀여과막(공칭공경 0.15㎛, CPVC)을 사용하여 에멀젼형 절삭유(MECOOL-7000, Megalube사) 수용액을 처리하였다. 막 오염을 효과적으로 감소시키기 위하여 대칭형 또는 비대칭형의 사인파형 투과유속 연속운전(Sinusoidal flux continuous operation; SFCO) 실험을 실시하였다. 분리막의 투과유속이 증가함에 따라서 막간차압이 증가하였으나, 대칭형 운전방식이 비대칭형 운전방식에 비하여 막간차압이 낮게 형성되어 막오염 제어에 효과적임을 확인할 수 있었다.

모양세포형 성상세포종에 의한 뇌교출혈- 증 례 보 고 -

곽형준,정신,강삼석,이정길,김재휴,김수한,이제혁 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

We report a case of brain-stem glioma with hemorrhage. A 24-year-old female presented with a 2-month history of headache, vomiting, right hemiparesis. Magnetic resonance image showed a 4×2.5cm sized mass with subacute stage hemorrhage in the left cerebellopontine angle. The mass and hemorrhage was surgically removed and pathological findings were consistent with pilocytic astrocytoma with recent hemorrhage. The patient discharged with mild neurological deficit. Key words:Brain-stem glioma;Pilocytic astrocytoma;Hemorrhage.

대칭/비대칭 사인파형 연속운전 방식에 따른 에멀젼형 절삭유 수용액 내 평막의 막간 차압

원인혜,이현우,곽형준,정건용 한국막학회 2015 멤브레인 Vol.25 No.4

본 연구에서는 0.5 wt% 에멀젼형 절삭유 수용액에 평막형 분리막을 침지시키고 대칭 및 비대칭 사인파형 투과유속 연속운전(SFCO) 방식으로 실험하였다. 사용한 정밀여과막은 유효 막면적이 0.02 m2이고 공칭 세공크기가 0.15 μm이었다. 탁도 기준으로 에멀젼형 절삭유의 99% 이상이 제거되었으며 산기량이 증가할수록 TMP가 낮게 상승하였다. 비대칭형 SFCO 운전방식은 투과유속이 낮은 10∼15 L/m2·h 영역에서 대칭형 SFCO 운전방식보다 다소 유리하였다. 하지만, 투과유속이 높은 25∼30 L/m2·h에서는 대칭형 SFCO 운전이 매우 효과적임을 확인할 수 있었다. In this study, permeation experiments were carried out using the symmetric and asymmetric sinusoidal flux continuous operation (SFCO) modes for the submerged flat sheet membrane in the 0.5 wt% emulsion type cutting oil solution. The effective area and nominal pore size of the used microfiltration membrane were 0.02 m2 and 0.15 μm, respectively. The emulsion cutting oil was rejected over 99% based on turbidity. Transmembrane pressure increased lower as the aeration rates increased. The symmetric SFCO mode was a little more effective than the symmetric SFCO mode in low permeate flux between 10 and 15 L/m2·h. However, the symmetric SFCO mode was shown very effectively in high permeate flux between 25 and 30 L/m2·h.

Quercetin reduces the elevated matrix metalloproteinases-9 level and improves functional outcome after cerebral focal ischemia in rats

이정길,곽형준,Min Sheng Piao,장재원,김수한,김형석 Springer-Verlag 2010 Acta neurochirurgica Vol.0 No.-

본태성 다한증 환자에서 하나의 피부절개를 통한 내시경적 흉부교감신경 절단술

이정길,김재휴,곽형준,김인영,김태선,김수한,강삼석,이제혁,정신 대한신경외과학회 2002 Journal of Korean neurosurgical society Vol.31 No.1

Objective:Endoscopic thoracic sympathectomy is an effective procedure for primary hyperhidrosis. The author present a retrospective analysis of uniportal endoscopic thoracic sympathicotomy for primary hyperhidrosis. Methods:Twenty patients underwent bilateral uniportal endoscopic sympathicotomy since August 1999. After collapsing the lung, a 6mm skin incision was made at the third intercostal space in anterior axillary line or just behind the posterior border of the pectoralis major and perforated with operating sheath. The endoscopy was 6.5mm in diameter and has one working channel(Karl Storz). An insulated 2mm coagulating forceps was introduced and T1-2 sympathicotomy with(13 patients) or without T2-3 sympathicotomy(7 patients) was performed. After the lung was fully inflated, the scope and the operating sheath were removed without chest tube, followed by single stitch. Results:Both sides were usually done within twenty minutes in a single stage. There was no postoperative complication except one case of pneumothorax and nineteen patients discharged at the following morning. Nineteen patients were satisfied with immediate and permanent relief of palmar perspiration. Recurrence of palmar hyperhidrosis has been noticed in one patient who underwent T1-2 sympathicotomy only, but the symptom was not so severe. There was no surgical mortality. Conclusion:The results of endoscopic sympathicotomy in patients suffering from severe palmar and axillary hyperhidrosis are favorable. Single-port technique is enough for the successful sympathicotomy with less postoperative discomfort and scars. Key words:Endoscopy;Hyperhidrosis;Sympathectomy.

대칭/비대칭 사인파형 연속운전 방식에 따른 에멀젼형 절삭유 수용액 내 평막의 막간 차압

원인혜,이현우,곽형준,정건용 한국막학회 2015 멤브레인 Vol.25 No.4

In this study, permeation experiments were carried out using the symmetric and asymmetric sinusoidal flux continuous operation (SFCO) modes for the submerged flat sheet membrane in the 0.5 wt% emulsion type cutting oil solution. The effective area and nominal pore size of the used microfiltration membrane were 0.02 m2 and 0.15 μm, respectively. The emulsion cutting oil was rejected over 99% based on turbidity. Transmembrane pressure increased lower as the aeration rates increased. The symmetric SFCO mode was a little more effective than the symmetric SFCO mode in low permeate flux between 10 and 15 L/m2⋅h. However, the symmetric SFCO mode was shown very effectively in high permeate flux between 25 and 30 L/m2⋅h. 본 연구에서는 0.5 wt% 에멀젼형 절삭유 수용액에 평막형 분리막을 침지시키고 대칭 및 비대칭 사인파형 투과유속 연속운전(SFCO) 방식으로 실험하였다. 사용한 정밀여과막은 유효 막면적이 0.02 m2이고 공칭 세공크기가 0.15 μm이었다. 탁도 기준으로 에멀젼형 절삭유의 99% 이상이 제거되었으며 산기량이 증가할수록 TMP가 낮게 상승하였다. 비대칭형 SFCO 운전방식은 투과유속이 낮은 10∼15 L/m2⋅h 영역에서 대칭형 SFCO 운전방식보다 다소 유리하였다. 하지만, 투과유속이 높은 25∼30 L/m2⋅h에서는 대칭형 SFCO 운전이 매우 효과적임을 확인할 수 있었다.

Characteristics of Wet and Dried Distillers Grains on In vitro Ruminal Fermentation and Effects of Dietary Wet Distillers Grains on Performance of Hanwoo Steers

김일영,안규철,곽형준,이유경,오영균,이상석,김정훈,박근규 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.5

Two experiments were conducted to evaluate the nutrient composition, in vitro dry matter disappearance (IVDMD) and organic matter disappearance (IVOMD) of three kinds of distillers grains (DG); i) wet distillers grains (WDG, KRW 25/kg), ii) dried distillers grains (DDG, KRW 280/kg), iii) dried distillers grains with solubles (DDGS, KRW 270/kg) produced from tapioca 70% and rice 30%, and to evaluate dietary effects of WDG on the performance of Hanwoo steers. In Exp. 1, twelve-WDG, four-DDG and one-DDGS were collected from seven ethanol plants. Average crude protein, crude fiber, neutral detergent fiber, and acid detergent fiber of WDG, DDG, and DDGS were: 32.6%, 17.8%, 57.5%, and 30.2% for WDG, 36.7%, 13.9%, 51.4%, and 30.5% for DDG, and 31.0%, 11.9%, 40.3%, and 21.2% for DDGS (DM basis), respectively. The DDGS had a higher quantity of water-soluble fraction than WDG and DDG and showed the highest IVDMD (p<0.05) in comparison to others during the whole experimental time. The IVDMD at 0 to 12 h incubation were higher (p<0.05) in DDG than WDG, but did not show significant differences from 24 to 72 h. The same tendency was observed in IVOMD, showing that DG made from tapioca and rice (7:3) can be used as a feed ingredient for ruminants. Considering the price, WDG is a more useful feed ingredient than DDG and DDGS. In Exp. 2, 36 Hanwoo steers of 21 months (495.1±91 kg) were randomly assigned to one of three dietary treatments for 85 days; i) Control (total mixed ration, TMR), ii) WDG 10% (TMR containing 10% of WDG, as fed basis), and iii) WDG 20% (TMR containing 20% of WDG, as fed basis). With respect to body weight and average daily gain, there were no differences between control and WDG treatments during the whole experimental period. Dry matter intake of control (9.34 kg), WDG 10% (9.21 kg) and 20% (8.86 kg) and feed conversion ratio of control (13.0), WDG 10% (13.2) and 20% (12.1) did not show differences between control and WDG treatments. Thus, the use of WDG up to 20% in TMR did not show any negative effect on the performance of Hanwoo steers.