독일바퀴의 變態에 따른 蛋白質의 Electrophoretic Pattern과 無機物質에 관한 硏究

吳世源,金東弼 광주보건대학 1986 論文集 Vol.11 No.-

The protein electrophoretic patterns, molcular weight of protein and the concentrations of mineral salts during metamorphosis of the german cockroach, Blattella germanica L. were measured by using SDS-polyacrylamide gel electrophoresis and Atomic absorption spectrophotometric methods, respectively. Healthy specimens were chosen as samples of each developmental stages; the second nymph, the fourth nymph, the sixth nymph and adult. Protein patterns were shown to form 24 bands according to their mobilities on electrophoresis but qualitative differences manifested in their patterns among all stages. At all developmental stages, the highest molecular weight was about 202,000 and the lowest one was about 17,000. A low molecular weight band was diminished, whereas an optical density of the high molecular weight band was in high concentration at adult stage. Mineral salts such as calcium, magnesium, zinc, iron, phosphorus, potassium and sodium were analyzed at all stages of metamorphosis. Changes in zinc, potassium and sodium concentrations through the coures of the physiological cycle showed generally a U-shaped curve during metamorphosis.

폐부종과 심정지가 발생한 페노바비탈 중독환자

오동렬,이운정,박규남,김세경,김영민,이환,유은영,최경호,정시경 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Phenobarbital is a long-acting barbiturate causing generalized depression of neuronal activity in the brain. Its effect is primarily achieved through enhanced GABA-mediated synaptic inhibition. Its use as an antiepileptic agent was first described in 1912. Before the introduction of phenytoin, phenobarbital is used as sedative-hypnotics. It is used for the treatment of epilepsy and status epilepticus. All barbiturates, including phenobarbital, have a high potential for abuse. They were frequently used for suicide attempts in the past, but they have in large part been replaced by benzodiazepines. The onset of symptoms depends on the drug and the route of administration. Mild to moderate barbiturate intoxication resembles ethanol inebriation with slurred speech, ataxia, and lethargy. Severe acute barbiturate intoxication is life threatening. Early deaths are generally cardiovascular-related. Hypotension, shock, pulmonary edema, and cardiac arrest that occurs with large doses are caused by depression of central sympathetic tone and as well as by direct depression of cardiac contractility. The potentially fatal oral dose of phenobarbital is 6-10g. We describe an 23-year-old woman with pulmonary edema, and cardiac arrest ingestion of 18grams of phenobarbital. She was completely recovered by successful cardiopulmonary resuscitation and homoperfusion. We report a case with literature review.

모바일 로봇의 지능제어

오세봉,심병균,Nguyen Van Quyet,한성현,박동준 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This paper achieves a research about remote control of robot based on voice recognition. Through real-time remote control and wireless network capabilities of an unmanned remote-control experiments and Home Security / exercise with an unmanned robot, remote control and voice recognition and voice transmission are possible to transmit on a PC using a microphone to control a robot to pinpoint of the source. Speech recognition can be controlled robot by using a remote control. In this research, speech recognition speed and direction of self-driving robot were controlled by a wireless remote control in order to verify the performance of mobile robot controller.

Spherical Harmonics 전개방법에 의한 간단한 이원자 분자의 쌍극자 모멘트의 계산

오세웅,김동희 木浦大學校基礎科學硏究所 1988 基礎科學硏究誌 Vol.6 No.-

The dipole moments for LiH, BH, NH, BF, and LiF molecules are calculated using the expansion method for spherical harmonics. The calculated numerical values of dipole moments for these molecules are agreement with the previous results. The orientation of dipole moments follows as ??, and ??.

백서의 심실세동성 심정지 모델에서 해마신경세포 손상에 대한 단백질 합성저해제의 효과

오동렬,채장성,박승현,김세경,최세민,박제영 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: The goal of successful resuscitation is not only to stop the process of ischemia as soon as possible but also to overcome the secondary injury process after resuscitation, which involves a complex interplay of mechanisms. Brain damage accompanying cardiac arrest and resuscitation is frequent and devastating. Cells die by one of two mechanisms: necrosis or delayed neuronal death. Delayed neuronal death may require protein synthesis. Neurons in the CA1 subfield of the hippocampus are selectively vulnerable to death after injury by ischemia and reperfusion. Death of these neurons occurs after an interval of 1 or 2 days. We assessed the effects of a protein synthesis inhibitor, cycloheximide(CHX), on hippocampal neuronal death of rats by using the ventricular fibrillation cardiac arrest(VFCA) model. Methods: The effect of CHX(3 mg/kg, s.c.) on hippocampal neuronal death was studied in two groups of 18 rats each, one group being subjected to a 2-min VFCA and the other to a 3-min VFCA. Each group was divided into three subgroups: control(groupⅠ,Ⅱ) without subcutaneous injection of CHX, "esp-12" of group Ⅰ/Ⅱ treated with CHX 12 hours after return of spontaneous circulation (ROSC), and "exe-24" of group Ⅰ/Ⅱ treated with CHX 24 hours after ROSC. The coronal sections of the hippocampus levels were stained with hematoxylin-eosin after 72 hours of survival. The histologic damage score(HDS) was used to assign a score to the total number of damaged neurons counted in each of the hippocampal CA1 subfields. Results: 1. There were not significant differences in heart rates, blood pressures, blood sugar, and blood gas in group I & Ⅱ during the pre-arrest steady state or at 5 min and 30 min after ROSC. 2. In group I & Ⅱ, the HDS, were significantly reduced in rats(I exp-12, 1.1 ±0.6;Ⅰexp-24, 1.3 ±0.5;Ⅱ exp-12, 1.4±0.7; and Ⅱ exp-24, 1.8±0.8) treated with CHX 12 hours or 24 hours after ROSC than control rats(1,2.5 ±0.9;Ⅱ,2.9±0.8)(p<0.05). Conclusion: These results suggest that delayed hippocampal neuronal death from ischemic insult after ventricular fibrillation cardiac arrest followed by resuscitation can be prevented by a protein synthesis inhibitor, CHX. Further experimental studies of the action mechanism of protein synthesis inhibitors to delayed neuronal death and clinical applications are required.

기체 주입 시스템에서 기-액 상호작용에 관한 연구

서동표,황세준,오율권 朝鮮大學校 機械技術硏究所 2001 機械技術硏究 Vol.4 No.1

Gas-injected system can be applied to various field such as metallurgical and chemical processing operations. So this study aims at presenting the relevant relationship between gas phase and liquid phase in gas-injected bath. The volume fraction, velocity, and temperature distribution of each phase were measured in order to predict the flow characteristics in gas-injected system. The gas discharged into the liquid bath loses its kinetic energy in a short distance from the nozzle exit, and then rises with a relatively uniform velocity due to buoyancy. As the gas rises upward in the liquid, the liquid entrains into the rising gas and a gas-liquid two-phase plume forms. In vertical injection systems, the gas-liquid plume is symmetric about the axis of the injection nozzle. In the region close to the orifice exit, the flow variables show steep spatial changes in both directions along the plume and across the plume. This region can be charaterized as a developing flow region.

임베디드 시스템에서 Mobile IP 프로토콜 구현

宋東勳,裵振勝,鄭燦赫,吳世德,李基源,劉忠烈,河載承,李光培,金玄郁 명지대학교 산업기술연구소 2005 産業技術硏究所論文集 Vol.24 No.-

With rapid growth of the internet, need for the mobile communication networks is increasing. In this paper, we implement and test Mobile IP Protocol in Embedded System. Our Mobile IP-based testbed consisted of two sub-networks and each sub-network was configured to operate independently through use of router. To satisfy integrated wired/wireless network model established on the testbed design and show generality of the testbed, we implemented mobile nodes, home agent, foreign agent and router on the basis of Linux operating system. As the results of the evaluation, we confirmed that mobile nodes operated properly according to Mobile IP Protocol.

Buerger병의 HLA항원에 관한 연구

김동일,김수신,오재욱,백세민 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.3

The purpose of this study is to investigate distribution of the HLA antigens among Korean patients with Buerger's disease and to compare the results of the previous studies. The subjects for this study consisted of 43 operated patients with Buerger's disease who have confirmed by the clinical criteria and angiographic findings and 262 normal korean healthy persons. The method of detection HLA antigens was the microtoxicity test deviced by Terasaki. The observed data are summarized as follows 1. The frequencies of HLA-A2, A3 and A24 were significantly higher among the patients with Bueraer's disease than in the control. 2. The frequencies of HLA-B35, B44, B5l, Bw6O and Bw6l were significantly higher among the patients with Buerger's disease than in the control. 3. By using Bonferoni inequality method, the only Statistically significant HLA antigens were HLA-A2, A24, B35 and B51.

심폐소생술후 혼수상태의 환자에서 체성감각유발전위의 예후 예측인자로서의 유용도

최세민,오동렬,최승필,박규남,김세경 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Background: The improved technique for cardiopulmonary resuscitation(CPR) has resulted in the survival of many patients who experienced cardiac arrest. However, mortality in resuscitated patients is high, and the survival rate without brain damage is very low. Various neurological examination models, neuro-imaging techniques, electrophysiological procedures, and biochemical tests have been studied with respect to the detection of cerebral damage and outcome, but an early, reliable prediction of individual outcomes is still uncertain. Methods: We studied twenty patients who had been in a coma for more than 24 hours after CPR, Somatosensory evoked potentials(SEP) were measured within the first three days after CPR. Results: Of the twenty patients, seven patients(35%) had a good outcome, and thirteen patients(65%) had a bad outcome. Of the eleven patients with loss of the cortical evoked potential's N2O peak, all had a bad outcome. Conclusion: SEPs are of great benefit in prognostic evaluation after CPR.

반복적인 경련을 동반한 아이소니아지드(Isoniazid) 중독환자의 치험 1례

이환,오동렬,정시경,김영민,이운정,김세경,이원재,최경호 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Isoniazid(Isonicotinic acid hydrazide) is an antimicrobial drug used since 1952 as a first line agent for the prophylaxis and treatment of tuberculosis. Isoniazid is well known for problems in population having a high prevalence of isoniazid use for prophylaxis or treatment of tuberculosis. But intentional or accidental isoniazid overdose is uncommon. The ingestion of toxic amounts of isoniazid causes recurrent seizures, profound metabolic acidosis, coma and even death. In adults, toxicity can occur with the acute ingestion of as little as 1.5g of isoniazid. Doses larger than 30mg per kg often produce seizures. When ingested in amounts of 80-150mg per kg or more, isoniazid can be rapid fatal. 40-year-old woman having previous pulmonary tuberculosis ingested 7gram of isoniazid(140mg/kg) to attempt suicide approximately 30 minutes prior to visit to our emergency medical center. She had recurrent generalized tonicclonic seizures and metabolic acidosis. We report one patient treated with pyridoxine, which was equivalent to the amount of isoniazid ingested and administered as a intravenous dose and oral dose