Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

동부(Vigna sinensis King) 자엽에서 α-amylase 활성에 미치는 식물 생장 조절의 효과

權義貞,權五溶 충남대학교 기초과학연구소 1997 忠南科學硏究誌 Vol.24 No.1

The effects of plant growth regulators on α-amylase activities in the embryonic axis-attached and detached cotyledons of Vigna sinensis King have been studied. In the absence of plant growth regulators, α-amylase activities in the embryonic axis-attached and detached cotyledons developing for 3 days have been generally increased, and than gradually decreased. When the 10 ^6M solution of gibberelli acid (GA_3), kinetin, indole-3-acetic acid (IAA), and 2,4-dichlorophenoxyacetic acid (2,4-D), have been exogenously supplied in the detached cotyledons for 3 days, α-amylase activities have occurred with about 2.4-fold in GA_3, 2.8-fold in kinetin, 1.8-fold in IAA, and 3.7-fold in 2,4-D, rather than the control. In the detached cotyledons treated with the 10 ^7M solution of zeatin, and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), α-amylase activities have been orderly increased with about 2-fold in zeatin, and 3.3-fold in 2,4,5-T. Consequently, it has been recently suggested that the 10 ^6M solution of 2,4-D besides the 10 ^7M solution of 2,4,5-T, which is a sort of synthetic auxin, has been obviously induced the development of α-amylase occurred in the embryonic axis-detached cotyledons of Vigna sinensis King.

만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정

오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.

주택욕실의 사례분석에 따른 유니버설디자인 적용방안

권오정,하해화 건국대학교 생활문화연구소 2000 생활문화ㆍ예술논집 Vol.23 No.-

Universal Design is a recent issue related to preserving human dignity, equality and human settlements. So the purpose of this study was to describe circumstances and problems of residential bathrooms, based on the results through the case studies by which every family members and to suggest the design considerations of residential bathroom planning for adapting universal design. Case studies were performed from Oct. 25 to Nov. 5, 1999 by 5 families with various physical conditions(the persons who have physical disabilities, visual impairments, the older people, pregnant women and persons without any disabilities). To investigate the current situations of the bathrooms, researchers visited five households and interviewed family members. Also the bathrooms were analyzed, evaluated and scored on the basis of the checklist including 56 items focusing on the concept of the universal design. The results of the case studies showed that the average score of all households was low. The specific design considerations for universal design residential bathrooms were suggested as conclusions of this study.

폐쇄성 수면 무호흡 환자의 측모 두부방사선계측사진 및 치아모형 연구

정미라,황상희,남기영,김종배,권오원 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.3

폐쇄성 수면 무호흡증이란 수면도중 주기적으로 호흡이 멈추는 증상을 말한다. 상악과 하악이 후퇴되어 있거나 하악이 작으며 수평적으로 기도 폭경이 좁고 혀가 후방에 위치하는 등 폐쇄성 수면 무호흡 환자의 전후방적인 악골 및 연조직 특성에 대한 평가는 많았으나 치열 및 악궁에 대한 평가가 부족하여 폐쇄성 수면 무호흡증 환자의 골격적 특징과 악궁의 폭경과 구개깊이와 수면무호흡지수와의 상관관계를 알아보고자 하였다. 계명대학교 의과대학 동산의료원 수면클리닉에 수면장애를 주소로 내원한 환자 중 수면다원검사와 측모 두부방사선계측사진과 치아모형이 갖추어진 38명의 남자를 대상으로 하여 치아모형과 측모 두부방사선계측사진, 수면무호흡지수와 체질량지수를 비교하였다. 수면무호흡지수와 악궁의 횡폭경, 구개깊이, 수직피개량 및 수평피개량과는 상관관계가 없었으며 수면무호흡군에서 상기도 폭경은 좁고, 하기도 폭경은 넓은 경향이 있었다. 수면무호흡지수와 상기도 폭경은 미약한 음의 상관관계를 가졌으나 하기도 폭경은 미약한 양의 상관관계를 가졌고, 수면무호흡지수가 클수록 하악 하연으로터 설골까지의 거리도 멀었다. To evaluate the cephalometric and dental characteristics of obstructive sleep apnea (OSA) patients, 23 OSA patients and 15 control, non-OSA, patients who visited the Sleep Disorder Clinic Center, Keimyung University were investigated. Patients who suffered from apnea-hypopnea episodes over 10 times per hour were diagnosed as having OSA after polysomnograph testing. Impressions were taken with alginate. Cephalometric radiographs were taken at maximum intercuspation. The dental cast measurements, including transpalatal width, intercanine width, intermolar width and palatal depth did not differ between the control and OAS groups and did not have a positive correlation with the apnea-hypopnea index (AHI). Upper airway width was statistically narrower than the control group. Upper airway width had a low negative correlation with AHI, but, lower airway width had a low positive correlation, and, the higher the AHI score, the longer the mandibular border to hyoid distance.

신경회로망 제어기를 이용한 PID 파라미터 추정에 관한 연구

權重東,裵銀敬,金恩基,全基英,李承桓,吳鳳煥,李勳九,金容珠,韓慶熙 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

In this paper, supposed to solve these problem to PID parameters controller algorithm using ANN. In the proposed algorithm, the parameters of the controller were adjusted to reduce by on-line system the error of the speed of IM. In this process, EBPA NN was constituted to an output error value of an IM and conspired an input and output. The performance of the self-tuning controller is compared with that of the PH) controller tuned by conventional method (Ziehler-Nichols). The effectiveness of the proposed control method is verified thought the Matlab Simulink and experimental results.

衣巖湖의 貝類에 關한 硏究 : A study on the gonadal tissues and demibranchs of Corbicula fluminea(Palaeoheterodonta: Corbiculidae)

권오길,이준상,박갑만 江原大學校 附設 環境硏究所 1989 環境硏究 Vol.6 No.-

의암호에 서식하는 재철(Corbicula fluminea)을 실험재로로 하여 생식세포형성, hermaphrodite에 의한 성비의 계정성 그리고 이에 따른 반새의 변화와 정확한 산란시기를 밝히고자 조직학적 방법에 의한 견구 조사를 실시하였다. 총 118개의 개체중 female 32개체(27.1%), female-hermaphrodite 75개체(63.5%)hermaphrodite 32개체(2.5%), male-hermaphrodite 7개체(5.9%), male 1개체(0.4%)로 전체적으로 female의 경향이 높았다. 산란은 2월과 3월에 난을 방출하는 난생의 형태이고 7월이후 11월까지 glochidia를 방출하는 난태생의 형태를 나타내었다. 外半?(outer-demibranch)가 보육낭으로 이용될 수도 있으나 內半?(inner-demibranch)가 주로 보육나으로 작용하였다. 수관 분리는 주로 inner-demibranch에서 나타났고, 산란시기에는 많은 개체가 수관이 분리되어 있었다. Corbicula fluminaea, one of two species in the family Corbiculidae living in the Lake Uiam was used as an experimental material. This research was done in order to deon in order to identify and describe the visceral sex. the demibranch morthology, and the seasonal gonad activity. The sexuality of C. fluminea was male, male-hermaphrodite (with a preponderance of testicular tissue over ovarian tissue), hermaphrodite (with approximately equal amount of male and female ponadal tissue), female-hermaphrodite (with a preponderance of the ovarian tissue), and female. The non-marsupial demibranch (namely, outer 2 in females and female-hermaphrodite, two in males and males and male-hermaphrodites) was divided by the secondary sept that in males and male-hermaphrodites) was divided by the secondary septa that produced secondary watertubes, resulting in triparitite organization. But, the outerdemibranch of all kinds has exhibited feebly the triparitite organization. In this species larvae were produced over two extended time periods, one in spring(oviparity) and one in fall (dvoviviparity).

苦蔘이 家免의 血管收縮抑制에 미치는 影響

권오율,남창규,정찬길 世明대학교 한의학연구소 1999 韓醫學硏究所 論文集 Vol.2 No.-

The purpose of this study was to analyze the effect and mechanism of Sophorae Radix on arterial experimental section contracted by PE(phenyl-ephrine). The results were summarized as follows; 1.Sophorae Radix significantly ingibited the PE-induced contraction of artery, accordingly as concentration of Sophorae Radix increased. 2.Sophorae Radix significantly ingibited the PE-induced contraction of artery both with intact endothelium and removed endothelium. 3.The ingibiting effect of Sophorae Radix on contracted strips was not changed by the pretreatment of NLA(Nω-nitro-L-arginine). 4.Sophorae Radix more significantly inhibited the PE-induced contraction of artery than KCI-induced. 5.The mechanism of inhibition of Sophorae Radix on contracted strips is suggested that Ca++ was blocked from the external medium.

A Study on DNA Sequences and Mutation of Integrase Region of Korean-type Bovine Leukemia Virus (BLV) pol Gene

권오식,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

Bovine leukemia virus (BLV) is a causative agent for lymphoma disease in cattle including cows worldwide. BLV shares similar virion structure and characteristics with other retroviruses. The pol gene of the BLV genome produced reverse transcriptase (RT) and integrase (IN) for important roles for BLV genome integration into host cell chromosomes that is known to be coded in the 3' side of the BLV pol gene (one third portion). In this study, we have sequenced 978 bp in the 3'side of the BLV pol gene from BLV 10C3 in order to determine the BLV IN region of it. And we compared it to the nucleotide sequences of an Australian BLV isolate. As a result, nucleotide sequences of the IN region of the Korean-type BLV pol gene were mutated at a rate of 3.7%. We can confirm that the typical mutations are such as Arg (AGG) → Lys(AAG), Thr (ACG) → Met (ATG), Ile (ATT) → Val (GTT), Asn (ACC) → His (CAC), Phe (TTT) → Leu (TTG) and Asn (ACC) → Asp (GAC). From the analysis of the sequencing data, we were able to determine the zinc-finger-like "HHCC" motif in the amino terminus of BLV IN, that was H-X_(3)-H-X_(25)-C-X_(2)-C. It was also found the DD35E motif in the IN catalytic domain as D-X_(56)-D-X_(35)-E. It fits very well to the consensus sequences of retroviral IN as well as HHCC motif.

음향방출을 이용한 저어널 베어링의 조기파손감지(Ⅱ) : Part Ⅱ : Intervention of Foreign Particles in Lubrication 윤활유 이물질 혼입의 영향 및 감시

권오양,윤동진,김경웅,정민화 韓國非破壞檢査學會 1994 한국비파괴검사학회지 Vol.14 No.2

일반적으로 회전기기의 저어널 베어링 부분은 윤활유 공급의 부족이나 윤활층에 이물질이 혼입되면 시스템의 고장이나 가동중단 등의 원인이 되기도 한다. 따라서 베어링 손상에 기인하는 사고와 관련된 안전운전 문제와 유지비용의 절감을 위해 여러가지 파괴 및 비파괴시험법들이 사용되어 왔다. 본 연구에서는 저어널 베어링에서 가장 발생하기 쉬운 윤활층에의 이물질이 혼입에 의해 야기되는 베어링 파손의 조기검출을 위해 음향방출 기술을 적용하였으며, 전보의 연구에 이어 좀더 정량적이고 체계적인 실험을 수행하였다. 실험실용으로 직접 제작한 모의베어링 시스템을 이용하여 여러 형태의 인위적인 이물질 흔입 상태를 만들어 실험하였으며 베어링 손상 및 결함 형태의 해석을 위해 AE rms level, 파형분석, AE 변수 등의 여러 파라메터를 사용하여 분석 고찰하였다. 그 결과 AE rms level의 변화가 이물질 흔입의 영향에 민감함을 보여주었으며 AE변수등 다른 정보들로부터 손상 원일별로 신호형태를 확인할 수 있었다. Journal bearings in the rotating machineries are vulnerable to the contamination or the insufficient supply of lubricating oil, which is likely to be the cause of unexpected shutdown or malfunction of these systems. Various destructive and nondestructive testing methods had been used for the reduction of maintenance cost and the operational safety problems due to the accidents related to bearing damages. In this experimental approach, acoustic emission monitoring in employed to the detection of incipient failure caused by intervention of foreign particles most probable in the journal bearing systems. Experimental schedules for the intervention of foreign particles was composed to be more quantitative and systematic than last study in consideration of minimum oil film thickness and particle size . The experiment was conducted under such designed conditions as inserting alumina particles to the lubrication layer in the simulated journal bearing system. Several parameters such as AE rms level, waveform, AE energy distribution and other AE event parameter are used for analysis and characterization of damage source. The results showed that the history of damage was well correlated with the changes of AE rms level and the types of damage source signal can be verified using other informations such an waveform, distribution of AE parameter etc.