신경회로망 제어기를 이용한 PID 파라미터 추정에 관한 연구

權重東,裵銀敬,金恩基,全基英,李承桓,吳鳳煥,李勳九,金容珠,韓慶熙 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

In this paper, supposed to solve these problem to PID parameters controller algorithm using ANN. In the proposed algorithm, the parameters of the controller were adjusted to reduce by on-line system the error of the speed of IM. In this process, EBPA NN was constituted to an output error value of an IM and conspired an input and output. The performance of the self-tuning controller is compared with that of the PH) controller tuned by conventional method (Ziehler-Nichols). The effectiveness of the proposed control method is verified thought the Matlab Simulink and experimental results.

북한이탈주민의 생활실태 조사 : 경기도 부천시 원미구 춘의임대아파트 거주자를 중심으로

오봉욱, 최종복, 권혁철 가톨릭대학교 사회복지연구소 2010 사회복지리뷰 Vol.15 No.-

상악골의 성장량 및 형태변화에 관한 누년적 연구

한상봉,권오원 慶北大學校 齒科大學 1992 慶北齒大論文集 Vol.9 No.1

정상교합자 남녀 각각 20명을 8세에서 16세까지 격년으로 촬영한 측모 두부 방사선 규격사진을 이용하여 상악골의 성장량과 형을 분석하여 다음과 같은 결과를 얻었다. · 각 계층항목의 남녀별, 연령별 평균치를 얻었다. · 남녀 모두 깊이 성장보다 높이 성장쪽이 성장량이 더 많았다. · 남자의 성장량이 여자보다 많았으며 특히 상악의 높이 성장에서 많았다. · 8세때는 거의 유사한 상악골 형태가 14세에서는 남자가 여자보다 후연부를 제외하고는 전반적으로 더 컸다. The primary purpose of this study was to know the longitudinal changes in the amount of growth and the form of maxilla. From the analysis of longitudinal cephalograms derived from 20 boys and 20 girls from 8 to 16 years of age with normal occlusion, the following results were obtained. 1. The author made the tables of means and standard deviations of Korean boys and girls in each item, sex & age. 2. The growth changes in the height of the maxilla were larger than those of the depth in both sexes. 3. The total amount of growth during 8 years was larger in boys than in girls, expecially in the height growth of the maxilla. 4. At the age of 8, there was no significant difference between boys and girls, but at the age of 14, the form of the maxilla became larger in boys than in girls except for the posterior margin.

전자공학교육과 실험교과내용에 관한 연구

홍봉식,김태균,오승엽,김환우,권오석 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(A)

The currenty offered experiment courses are completely reconsidered and reconfigured. The whole subjects are divided into 10 seperate courses, each of which should represent either basic or advanced stages of differing fields of the electronic engineering. It has been aimed that the courses form an elaborate hierachy so that they are minimally redundant but linked to one another in their fringes. Also, it has been pursued that the new courses should not fall obsolete in at last next five years exploring the maximum possibilities of the currently available equipments.

한국인에서 혈액응고인자 IX 유전자의 제한효소 절편길이 다형성에 관한 연구

전봉균,이풍연,권오병,이정민,안주미,권무식 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

DNA-based prenatal diagnosis or carrier detection for hemophilia B in Korean has been developed by RFLPs. The polymorphisms were Taq I and Xmn I . Genomic DNAs were extracted from the blood of 56 females and 10 males at the age of twenty. The PCR primers were chemically synthesized by the method of phosphoramidite. Taq I-59 & -39 derived from flanking sequences of intron 4 generate 163nt fragment. And, Xmn 1-59 & -39, derived from the flanking sequences of intron 3 allow amplification 222nt fragment. Using Polymerase chain reaction(PCR) method, each segment(intron 3-Xmn I, intron 4-Taq I) was amplified with each primers and the genomic DNA as template. The amplified DNA fragments were treated with an appropriate restriction enzyme. The Xmn I polymorphism of the factor IX gene was detected on agarose gel as segments of 154 and 68nt, respectively. The heterozygote frequency, calculated from the allele frequencies (0.025/0.975) in intron 3-Xmn I polymorphism, was 4.8%. In case of intron 4-Taq I polymorphism, there is no polymorphic site. So that the heterozygote frequency calculated from the allele frequencies (0.0/1.0) in intron 4-Taq I polymorphism, was 0%. Thus, the two intragenic polymorphisms predicted to be informative was 4.8% in this study. The results are not correlated with those obtained from the Caucasian. It suggests that Korean exhibit different patterns of Xmn I and Taq I polymorphism in the human coagulation factor IX gene.

CFRP 판재의 섬유방향에 따른 절삭성 평가

신봉철,하석재,강민형,권오양,조명우 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

In recent, the CFRP(Carbon Fiber Reinforced Plastics) composite has been widely used because it has light-weight and high mechanical strength. Therefore, CFRP composite is applied to variable industrial areas such as aerospace, automobiles, sporting goods, ships and so on. Generally, CFRP composite has been used in the industrial field by mechanical cutting processes. In this research, the CFRP composite specimen are laminated by 64plies with orientation angles such as 0°, 45°, 90° and [0°/±45°/90°]4S. The results are analyzed with cutting force and cutting surface.

전립선암의 예측인자로서 전환대 전립선특이항원의 유용성

김현학,권동득,오봉렬,박광성,류수방,박양일 全南大醫大 2001 전남의대학술지 Vol.37 No.3

조혈모세포이식 후 골성장인자의 변화 및 골대사에 미치는 영향 : Impact on Bone Mineral Metabolism

백기현,오은숙,오기원,이원영,김혜수,권순용,한제호,강무일,차봉연,이광우,손호영,강성구,김춘추 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

연구배경: 각종 장기이식의 시행이 많아지고 이식 후 생존율이 증가함에 따라 이식 후 합병증에 대한 관심 또한 높아지고 있다. 조혈모세포이식 후에도 다양한 내분비적 합병증이 발생할 수 있으며 골격에 대한 합병증도 문제점으로 대두되고 있다. 조혈모세포 이식 후 발생하는 골소실에는 이식 후 초기의 골형성 저하와 골흡수 증가가 중요한 역할을 담당하리라고 추측되는데 이러한 골재형성불일치(biochemical uncoupling)에 골 성장인자들이 미치는 영향에 대해서는 알려진 바가 없다. 본 연구에서는 조혈모세포이식 전, 후로 말초 혈액에서 IGF-I, FGF-2, M-CSF같은 성장인자의 변화를 알아보고, 이들 성장인자의 변화가 조혈모세포이식 후의 골형과 골흡수에 미치는 영향 및 이식 후 발생되는 골량 소실과의 연관성을 확인해 보고자 하였다. 방법: 여러 가지 혈액질환으로 인해 동종 골수이식을 시행 받은 환자들을 전향적으로 관찰하였으며 이식 전 및 이식 후 1주, 2주, 3주, 4주 및 3개월, 6개월 1년에 말초 혈액에서 골교체표지자를 측정하였다. 이식 전 및 이식1년 후에 요추골 및 대퇴골 골밀도를 측정할 수 있었던 36명의 환자들을 대상으로 냉동 보관되어 있던 혈청을 이용하여 IGF-I, FGF-2 및 M-CSF를 시기별로 측정하였으며 이들 성장인자와 골교체표지자의 변화 및 골밀도 변화 사이의 상관관계를 확인하였다. 결과: 골흡수 표지자인 혈청 ICTP는 이식 전에 비해 이식 후 4주까지 점차 의의 있게 증가하다가 이후 6개월까지 더욱 증가한 후 감소하였다. 골형성 표지자인 osteocalcin은 이식 후 3주까지는 점차 감소하다가 이후 증가하여 이식 후 3개월 및 6개월에 기저치보다 통계적으로 유의하게 증가한 후 감소하였다. 혈청 IGF-I과 FGF-2는 각각 이식 후 3주 및 1주까지 의미있게 감소하다가 이후 증가하였으며 혈청 M-CSF는 이식 후 1주째에 기저치에 비해 의미 있게 증가하였다가 이후 기저치로 회복되었다. 이식 1년 후 평균 요추부 골밀도는 5.2% 감소하였고 평균 근위대퇴골 골밀도는 11.6% 감소하였다. 이식 전 및 이식 후 3주에 측정한 IGF-I과 같은 시기에 측정한 오스테오칼신 사이에 유의한 상관관계가 관찰되었으며 이식 후 3주째의 M-CSF와 골흡수표지자인 M-CSF 사이에서 의미 있는 양의 상관관계를 관찰할 수 있었다. 이식 후 3주 및 3개월에 IGF-I이 낮은 환자일수록 이식 1년 후 근위대퇴골에서의 골소실이 많은 것으로 분석되었다. 결론: 조혈모세포이식 후 발생하는 골소실에는 기존에 알려진 기저질환의 영향, 성호르몬의 감소, 면역억제의 투여, 골수기질세포와 조골세포의 손상 및 이식초기 사이토카인의 변화이외에도 골성장인자가 관련이 있음을 확인하였고, 이는 이식 후 발생되는 골량소실에 중요한 역할을 할 것이라고 사료된다. Background: A loss of bone mass is usually detected after a bone marrow transplantation (BMT), especially during the early post-transplant period. We recently reported that enhanced bone resorption following a BMT was related to both the steroid dose and the increase in IL-6. We also suggested damage to the marrow stromal microenvironment, by myoablation, partly explains the impaired bone formation following a BMT. It is well known that some growth factor play important role in bone growth and osteogenesis. However, the pathogenetic role of bone growth factors in post-BMT bone loss is unknown and data on the changes in the growth factors, in accordance with bone turnover markers and bone mineral density (BMD) changes are scarce. We investigated changes in bone growth factors such as IGF-I (Insulin-like growth factor-I), fibroblast growth factor-2 (FGF-2) and Macrophage colony stimulating factor (M-CSF), during the post-BMT period, and assessed whether the growth factor changes influenced the bone turnover and post-BMT bone loss. The present study is the first prospective study to describe the changes in bone growth factors following a BMT. Methods: We prospectively investigated 110 patients undergoing a BMT, and analyzed 36 patients (32.4±1.3 years, 17 men and 19 women) whose BMDs were measured before, and 1 year after, the BMT. The serum biochemical markers of bone turnover were measured before, 1, 2, 3 and 4 weeks, 3 and 6 months, and 1 year, after the BMT. The serum, FGF-2, IGF-I and M-CSF levels were measured before and 1 and 3 weeks, and 3 months after the BMT. The correlation between the changes of growth factors and various bone parameters was analyzed. Results: The mean bone losses in the lumbar spine and total proximal femur, calculated as the percentage change from the baseline to the level at 1 year, were 5.2(p<0.05) and 11.6%(p<0.01), respectively. the serum type I carboxyterminal telopeptide(ICTP), a bone resorption marker, increased progressively until 6 months after the BMT, but thereafter decreased, to the base value after 1 year. Serum osteocalcin, a bone formation marker, decreased progressively, until 3 weeks after the BMT but then increased transiently, and finally returned to the base level at 1 year. The serum IGF-I and FGF-2 also decreased progressively until 3 weeks 1 week after the BMT, respectively, then increased to the base values at 3 months. The serum M-CSF increased briskly at 1 week post-BMT, then decreased to the base level. There were positive correlations between the percentage changes from the baseline proximal femur BMD and the IGF-I levels 3 weeks and 3 months (r=0.52, p<0.01, r=0.41, p<0.05) post BMT. A significant correlation was found between the IGF-I and osteocalcin levels pre-BMT, and 3 weeks after the BMT. Another positive correlation was found between the M-CSF and the ICTP levels at 3 weeks post BMT (r=0.54, p<0.05). Conclusion: In conclusion, there were significant changes in the serum IGF-I, FGF-2 and M-CSF levels in the immediate post-BMT period, which were related to a decrease in bone formation and loss in the proximal femoral BMD during the year following the BMT (J Kor Soc Endocrinol 17:664∼674, 2002).

20km와 150km의 도로싸이클 주행이 혈중 렙틴, 지질과 호르몬 수준에 미치는 영향

최용어,권봉안,오재근,김범수,조준용,김문희 한국체육대학교 체육과학연구소 2000 韓國體育大學校附屬 體育科學硏究所論文集 Vol.19 No.1

Serum leptin, glucose, lipid profiles (free fatty acid, triglyceride, total cholesterol) were determined in two groups of subjects undergoing long and short strenous cycle race, 8 men who fasted overnight and then pedaled 20km cycle race and 8 men, 150km cycle race, respectively, Blood samples were collected before race, immediately after cessation of race and 2hr, 6hr after the end of race period. Cyclist pedaling 20km cycle race and cyclist pedaling 150km cycle race showed no statistical differences in leptin level. After 6hr of rest, leptin concentrations were gradually decreased but showed no statistical different in both groups. Epinephrine (p〈.01) and norepinephrine (p〈.001) concentration in comparison to pre-race levels were increased significantly. But insulin concentration in comparison to pre-race levels were decreased significantly (p〈.001). Glucose (p〈.01), free fatty acid (p〈.001), cholesterol (p〈.001) and triglyceride (p〈.01) were increased immediately after cessation of race in both groups.

배추(Brassica campestris L. var. pekinensis Makino)의 cDNA library 구축 및 상동성 비교

안주미,권오병,전봉균,이풍연,이정민,권무식 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

Expressed sequence tag(EST) has a good value to discover a new gene or to study its structure. Some 20 ESTs were generated to obtain new genetic resources of chinese cabbage(Brassian campestris L. var. pekinensis Makino). Poly A+ RNAs were isolated from 10-day-old seedlings grown at 25℃ under the day light. cDNA gene bank was constructed using λ ZAP /cDNA synthesis /Giga Pack Gold Packing kit. About a million clones were able to obtain from the library. All the clones examined so far had insert DNAs. Nucleotide compositions of randomly selected clones were determined by the Sanger mthod. The DNA sequences were compared with those deposited in the GenePept and GenBank database to figure out nucleotide homologies. Two ESTs showed significant similarities to the enlisted sequences. They are chloroplast GADPH subunit of Arabidopsis thaliana and carbonic anhydrase of A. thaliana. The full DNA sequences of the two clones are being determined. The cDNA gene bank constructed. in this experiment will being used to isolate more genes induced by the light in the plant.