3원계 화합물 반도체의 에너지 밴드 구조와 전기적 특성 연구

김철회,김형관,한백형 漢陽大學校 基礎科學硏究所 1994 基礎科學論文集 Vol.13 No.-

Empirical pseudopotential 방법을 이용하여 아연 화합물 반도체의 에너지 밴드 구조를 구하였다. ??의 에너지 간격은 InSb의 조성비에 따라 ??=0.606χ²-0.727χ+0.361를 얻었고 전자이동도는 χ=0.6, 합금산란 포텐셜이 0.82eV, 온도가 77。K, 불순물 농도가 ??일때 6.7 × 10⁴cm/V-s을 얻었다. Energy band structure of zinc-blende semiconductors is calculated by the empirical pseudopotential method using the adjustable parameter. Energy gap of ?? with InSb mole fraction is ??=0.606χ²-0.727χ+0.361 and its electron mobility is found to be a high value of 6.7 × 10⁴cm/V-s with mole fraction x=0.6, alloy scattering potential ΔU=0.82eV, Temperature T=77。K, and impurity concentration ??.

중년여성들의 숙련자와 비숙련자간 수영운동 후 신체조성 비교

김형묵,박관도 청주대학교 학술연구소 2004 淸大學術論集 Vol.4 No.-

The purpose of this study is to analyze 'how swimming' for twelve weeks affects the body development of middle-aged women. An investigation into the body development of thirteen women in a two-month period and a one-year period was performed. Each woman that participated in the swimming trials was asked to continually practice one hour in the morning three times a week before and after the investigation. The study arrived at the following conclusion. 1) The weight after swimming was found to have decreased significantly by 0.7kg in the case of the unskilled group and 0.6kg in the case of the expert group. 2) FAT(%) before and after investigation had similarly decreased by 2% in the case of the unskilled group and by 1.7% in the case of the expert group. FAT percentages(%) of the unskilled group were reduced by more than 0.3% when compared to the expert group. 3) FAT mass(kg) before and after the investigation had similarly decreased by 1.3kg in the case of the unskilled group and by 1.1kg in the case of the expert group. FAT mass(kg) of the unskilled group was reduced by more reduced by more than 0.2kg in comparison with the expert group. 4) The variation of lean body mass(kg) before and after the investigation had increased by 0.8kg in the case of the unskilled group and by 0.5kg in the case of the expert group. Lean body mass(kg) of the unskilled group increased by more than 0.3kg in comparison with the expert group. 5) Total body water before and after the unskilled group and expert group didn't change. In summation, swimming for one hour three times a week was found to reduce the FAT(%) and FAT mass(kg) of middle-aged women.

호흡기 감염에서 Sparfloxacin 의 임상적 유용성에 대한 Enoxacin과의 비교 검토

김주옥,김선영,김관형,서지원,박석영,이종진,박성학 대한감염학회 1995 감염 Vol.27 No.4

목적:폐렴, 기관지염, 만성기관지염에서 fluoroquinolone제제로서 항균력이 강하고, 혈중 반감기가 길고, 객담과 조직내 농도가 높은 sparfloxacin의 안전성과 효과를 enoxacin과 비교하기 위해 본 연구를 시행 하였다. 방법:1994년 10월부터 1995년 4월까지 충남대 부속병원과 대전 성모병원에 내원한 폐렴, 급성기관지염, 만성기관지염이 급성으로 악화된 환자 63명을 대조군(32명)(enoxacin 100 mg 1일 3회 경구투여), 실험군(31명)(sparfloxacin 200mg 1일 1회 경구투여)으로 나누어 임상증상, 세균학적 객담 검사, 혈액검사, 실험실내 항균력검사로 그 치료율 및 안전성을 비교하였다. 결과: 1) 임상종합 평가, 세균학적 균소실, 안전성, 유용성에서 두군간에 의미 있는 차이는 없었다. 2) 시험관내 항균력검사상 MIC가 실험군이 대조군보다 현저하게 낮았다.(p<0.05). 3) 경미한 두통, 식욕감퇴, 상복부 불쾌감, 설사등이 대조군 9예, 실험군 7예에서 발생하였고, 검사실 소견상 SGOT 혹은 SGPT 의 일시적 경미한 상승이 대조군 2명, 실험군 3명에서, 혈중 creatinine 상승이 실험군 2명에서 있었으나 경미하였다. 결론:이상의 결과로 sparfloxacin은 폐렴, 급성기관지염, 만성기관지염의 악화에서 하루 한번 투여로 enoxacin 하루 3번 투여와 유사하게 효과적이고 안전하며, 시험관내 항균력이 enoxacin보다 월등히 우수하여 임상에서도 유용하게 사용될수 있을것으로 생각된다. Background: Sparfloxacin, a new oral quinolone, has a broad spectrum, potent antimicrobial activity, prolonged half life, high concentration in sputum. The clinical efficacy and safety of sparfloxacin have been reported by some previous clinical studies performed in Japan. The objectives of this study were to evaluate the clinical and antimicrobial efficacy of this drug in respiratory tract infections compared to those of enoxacin. Methods:We performed an open controlled, randomized study in 63 patients with acute bronchitis, pneumonia, and exacerbation of chronic bronchitis at Chung Nam University hospital and Dae Jeon St. Mary's hospital from October, 1994 to April, 1995. In the control group(n=32), 100 mg enoxacin was administered orally 3 times a day and in the test group(n=31), 200 mg sparfloxacin once a day. Results: The results were as follows; 1) There were no significant differences between the two groups in clinical efficacy, bacteriological finding, and usefulness. 2) Means and SD of MICs were 0.44±0.89 ㎍/ml in the control group, 0.13±0.24 ㎍/ml in the test group. There was a significant difference in MICs between the two groups(p<0.05). 3) Headache, epigastric discomfort, and loss of appetite were observed in 7 cases of the control group and in 9 cases of the test group, and transient elevations of hepatic enzyme in 2 cases of the control group, and in 3 cases of the test group. There was mild elevation of serum creatinine in 2 cases of the test group. Those laboratory abnormalities by therapy might be associated with their underlying diseases. There were no significant adverse effects caused by the drugs Conclusion:In conclusion, sparfloxacin of 200 mg once a day was as effective and well tolerated as enoxacin of 100 mg three times per day in the treatment of respiratory tract infections. Sparfloxacin is more potent antibiotics because MICs of sparfloxacin were very lower than those of enoxacin.

Escherichia coli(M15)을 이용한 serotonin N-acetyltransferase 유전자의 발현

김용만,정미영,윤경식,진병관,백행운,조용호,백형환 慶熙大學校 1997 論文集 Vol.26 No.-

AA-NAT cDNA was obtained by RT-PCR technique from total RNA of rat sacrified at night(02:00am). pCRNAT was cloned using the pCRII vector with insertion of AA-NAT cDNA(about 1.4 kb) at EcoRI site. For the expression of the gene, pQECNAT was subcloned, in which the coding region of AA-NAT was inserted into expression vector pQE30 at BamHI and HindIII sites. According to the experimental results, Escherichia coli strain M15, transformed by the expession vector pQECNAT, was selected as a host to express AA-NAT gene with the induction of isopropyl β-D-thiogalactoside(IPTG). Optimal condition for the expression of AA-NAT gene was achieve from the experimental results, showing that the expression of the protein was inducible much 19.800 ± 2,200 dpm per ml of culture volume in 4 hours at the concentration of 2 mM IPTG. Partial purification through the affinity column(Ni-NTA agarose) binding to the continuous 6 histidine residues of protein resulted in 5 times more increase in the specific activity of AA-NAT than that of the homogenate of bacterial pellet. These experimental results will provide basic data in further study for the enzymatic kinetics and antibody production of AA-NAT.

TRISS Method와 ASCOT Method를 이용한 외상환자의 생존율 분석

김형수,배성만,양혁준,박철완,이근,고영관 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Despite traumatic injuries cause serious problems in our society, there are few adequate and objective scoring system that assess the severtiy of trauma patients. The Major Trauma Outcome Study(MTOS)in United States deisgned the TRISS(Trauma Score & Injury Severity Score)method by means of Revised Trauma Score(RTS),Injury Severity Score(ISS0,and age,while Champion et al deviced ASCOT(A Severtriy Characterizaiton Of Trauma)method to overcome the limitation of TRISS. This study attempted to make a comparison between TRISS and ASCOT by using date for 422 injured patients which were collected form September,1993 to February,1994. Ascot and TRISS were compared in their sensutivity,Specificity,disparity and Z-statistics. 1)Sex ratio of male to female was 2.8:1 and the commonest age of trauma patients was thirties (23.8%). 2)The average probability of survival(Ps)for 442 patient by TRISS method was 0.9228 and that of ASCOT method 0.9356. 3)Disparity of Ps between survival and non-survival using TRISS and ASCOT was relatively low for both indexes as 0.3507 and 0.3296, respectively. 4)The sensitivity rates(number of patients predicted to die who actually died/total who actually died)for the non-survival of both TRISS and ASCOT method were low (35.0%),but the specificity rates(number of patients predicted to live who actually lived/total who actually lived)for the survival of TRISS and ASCOT were 99.1%and 99.6%respectively. 5)Z-statistics(difference between predicted and actual number of death)of both TRISS(1.3224)and ASCOT(1.2234)resulted in positive value which meant that actual number of death exeeded predicted number of death. 6)The ASCOT that have presumed to be more accurate method for patients with head trauma and with multiple injuries to one portion of body,had its intricacy and difficult points in practical application. And the difference between the result of ASCOT and TRISS was not so significant. 7)It is thought that a new, more comprehensive index would like to be developed and thoroughly tested on a variety of data sets in order for it to be used in trauma system quality assurance evaluation.

최대운동시 당질상태에 따른 혈장 에피네프린과 노르에피네프린의 반응

김형렬,황수관 대한스포츠의학회 1995 대한스포츠의학회지 Vol.13 No.1

The purpose of this study was to investigate changes of plasma epinephrine and norepinephrine during maximal exercise in various glycogen conditions. The subjects were composed of 7 male college students. They performed graded exercise test by way of bicycle ergometer in normal glycogen condition, glycogen-depleted condition and glycogen-loaded condition. Glycogen depletion and loading condition were formed as a results of exercise and dietary. plasma epinephrine and norepinephrine were analyzed of blood samples extracted every 3 minutes until exhaution. On the basis of the results analyzed in this study, conclusions were drawn as follow. 1. Plasma norepinephrine in this study, conclusions were drawn as follows. condition with work loads, and difference between glycogen-loaded condition and glycogen depleted condition was significant (p<0.05) from the work load of 120W. 2. Change of norepinephrine/epinephrine was increased in both normal glycogen condition and glycogen-loaded condition with work loads, and differences among three conditions were not significant on the whole.

合成洗劑가 빨간집모기의 生態, 生理學的 特性에 미치는 影響

金正和,李炯來,朴垠澈,李容揆,崔觀善 충북대학교 농업과학기술연구소 1995 農業科學硏究 Vol.12 No.2

It is considered a general experience that migration from rural to urban areas will go on in any developing countries pursuing economic development through industralization. In Korea, migration is considered one of the serious socio- economic problems because it has been made excessively fast than any other countries' experiences. The socio- economic problems originates in migration can be classified in two ways ; the one is the overpopulated problems of urban areas and emptied villages problems of rural areas, and the other is the shartage agricultural labor farce problems symbolized by the increasing idle cultivated land. To relieve migration effectively, the developing policies should be converted from pursuing fast industralization and urbanization to balance growth between areas and industries. Moreover problem solving political measure should be converted from partial and corresponding approaches to total approaches containing economic, social and institutional side-view.

韓國의 工業所有權 制度에 關한 硏究

金寬衡 건국대학교 행정대학원 1989 建國大學校 行政大學院 硏究論叢 Vol.17 No.-

서울 대기 에어로솔의 물리적 특성 : 0.01~1.0㎛범위 에어로솔의 표면적 및 체적분포의 월변화

김형관,김필수 漢陽大學校 環境科學硏究所 1988 環境科學論文集 Vol.9 No.-

입자 크기 0.01~1.0 ㎛범위 서울 대기 aerosol의 표면적 및 체적의 월변화를 1984년 5월부터 10월에 걸쳐 전기적 aerosol분석기로 결정하였다. 그 결과 표면적 분포는 0.13 ㎛ 근처에서 극대를 가지는 一山型 곡선을 보였다. 체적분포는 0.2 ㎛ 근처에서 극대를 나타내며 직경 1.0 ㎛ 이상에서 제2의 극대가 있을 가능성을 보였다. 이러한 분포는 직경이 커질수록 입자의 개수가 점점 줄어드는 입자수 분포와는 판이하게 다른 것이었다. 표면적 및 체적분포의 월변화는 춘계에 최고의 농도분포를 보이고 하계에 최저를, 그리고 추계에 점점 증가하는 양상을 나타냈다. 이러한 계절변화는 자연환경과 기상요인의 변화와 밀접히 연관된 것이었다. Monthly variation of surface and volume distributions of Atmospheric aerosols over the size range 0.01~1.0 ㎛ has been determined using an electrical aerosol analyzer in Seoul from May through to October 1984. The results indicate that the surface distribution reveals a monomodal curve with its maximum in the vicinity of 0.13 ㎛ for each month, while the maximum of the volume distribution appears at about 0.2 ㎛ suggesting a possible existence of second maximum somewhere D>1.0 ㎛. These distributions are quite different from the aerosol number distribution which is characterized by a continous decrease of number concentration as increasing particle size. The monthly variation of the surface and volume distributions shows their highest values in spring and lowest in summer. followed by a gradual increase in autumn. The seasonal variation is closely related with change of natural environment and meteorological factors.

대학생의 학업성취 수준 실태 분석 연구

김형관,신현석,서민원,황기우 고려대학교 교육문제연구소 2001 敎育問題硏究 Vol.15 No.-

본 연구는 대학생의 학업성취 수준을 사전에 선정된 사회 문화적 배경요인에 따라 실증적으로 분석하여 그 실태를 알아보는데 목적이 있다. 본 연구는 연구주제와 관련된 선행 문헌고찰을 바탕으로 대학생의 학업성취를 인지적 측면에서 ① 실제 학점 평균과 ② 지각된 성취수준(전공지식 습득, 교양지식 습득, 논리·분석적 사고력, 창의력) 등 두 가지로 개념화하였다. 그리고 학업성취와 관련된 사회 문화적 배경요인은 크게 대학생의 ① 개인적 배경요인, ② 가정배경요인, ③ 대학배경요인 등 세 가지로 구별하였다. 본 연구의 대상은 전국에서 표집된 6개 종합대학 1,781명의 대학생들이다. 이들을 대상으로 학업성취요인과 사회 문화적 배경요인들을 설문화하여 수집된 자료를 분석한 결과, 개인적 배경변인에서는 계열별, 거주형태, 일일 평균 공부시간 등의 변인은 학업성취에 차이를 가져오는 것으로 나타났다. 가정 배경변인에서는 출신지역과 부모의 학력 정도에 따라 학업성취 수준이 다르게 나타났다. 한편, 대학 배경변인 별로는 대학설립 유형, 학교 소재지, 입학전형 방식 등의 변인들이 학업성취 수준의 차이를 가져오는 것으로 밝혀졌다.