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고혈압의 침치료에 대한 문헌고찰 : 국내 임상 연구를 중심으로
정상연,황예채,조승연,이한결,권승원,정우상,문상관,박정미,고창남,박성욱,Sang Yeon, Jung,Ye-Chae, Hwang,Seung-Yeon, Cho,Han-Gyul, Lee,Seungwon, Kwon,WooSang, Jung,Sang-Kwan, Moon,Jung-Mi, Park,Chang-Nam, Ko,Seong-Uk, Park 대한중풍순환신경학회 2022 대한중풍.순환신경학회지 Vol.23 No.1
■Objectives This study aimed to collect and analyze clinical studies on the significance of acupuncture in the treatment of hypertension among Korean patients. ■Methods Among Korean patients with a blood pressure (BP) of 120 mmHg or higher and a diastolic BP of 80 mmHg or higher, those, treated with acupuncture only, were included. A literature search was conducted through 'Embase', 'Medline', 'Science and Technology Information Integration Service (NDSL)', 'Traditional Korean Knowledge Portal (OASIS)', 'PubMed', and 'Scopus'. The search keywords were (hypertension OR 'blood pressure') AND acupuncture. The papers, published before the day of the search (02. January 2022), were included in this study. ■Results Among the 12 selected papers, seven involved randomized controlled trial (RCT), four before-and-after studies, and one case series. The number of RCTs has increased yearly. The treatment methods used in the studies included needle acupuncture in eight studies, auricular acupuncture in two, pharmacopuncture in one, and si-acupuncture in one. The average numbers of patients enrolled in RCTs, before-and-after studies, and case series were 21.1, 30, and 23 respectively. Six studies were conducted on prehypertensive patients, two on stage 1 hypertension patients, and four on stage 2 hypertension patients. The involved acupoints have been reported to be ST36 in eight papers, LI11 in four papers, and PC6 in three papers. The treatment period lasted for < 1 week in eight studies and 8 weeks in four studies. Acupuncture successfully lowered blood pressure in nine out of 12 studies ■Conclusions Acupuncture is a viable alternative treatment option for prehypertensive patients, who are not taking medications. Additionally, it is also useful in further lowering the BP of patients with stage 1 and stage 2 hypertension in the short term. Large-scale and long-term studies on acupuncture for hypertension should be conducted.
어지럼증을 호소하는 서맥성 부정맥 환자의 한의복합치료 1례
정소민,이성욱,하원정,조기호,문상관,정우상,권승원,이한결,So-Min, Jung,Seong-Wook, Lee,Won-Jung, Ha,Ki-Ho, Cho,Sang-Kwan, Moon,Woo-Sang, Jung,Seungwon, Kwon,Han-Gyul, Lee 대한중풍순환신경학회 2022 대한중풍.순환신경학회지 Vol.23 No.1
Brady-arrhythmia is defined as an arrhythmia in which the heart rate slows to less than 60 beats per minute. Brady-arrhythmia reduces cardiac output and causes changes in blood flow. As a result, dizziness occurs because not only ischemia occurs in the central nervous system, but also blood flow in major organs decreases. The insertion of an artificial pacemaker is known as almost the only treatment alternative for patients with brady-arrhythmia with symptoms. This study reports a case of 85 year old male diagnosed with brady-arrhythmia complaining presyncope type of dizziness. The patient underwent complex Korean medicine treatments by herbal medicine, acupuncture and moxibustion. The daily average value of pulse rate, K-DHI score, NRS score and the patient's subjective expression of symptoms were used as evaluation tools. This study suggested a significant improvement in symptoms through complex Korean medicine treatments without the use of anti-arrhythmic drugs or insertion of an artificial pacemaker in the patient with brady-arrhythmia complaining dizziness.
Role of clusterin in protection against hyperoxic lung injury in mice
( Jung Yeon Hong ),( Mi Na Kim ),( Eun Gyul Kim ),( Jae Woo Lee ),( Kyung Won Kim ),( Myung Hyun Sohn ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Purpose: Clusterin (CLU) is a highly conserved glycoprotein whose gene expression is ubiquitous and attribute to many cellular physiologic functions, including cell-cell interactions, complement inhibition, lipid transportation, cell survival, and apoptosis. We hypothesized that CLU might be important in hyperoxic acute lung injury. Methods: CLU expression and signaling was determined in airway epithelial cells after in vitro hyperoxia challenge. Using a murine model of hyperoxia-induced lung injury, the role of CLU was determined using CLU-deficient mice. CLU and cell death was detected by immunohistochemistry, real-time PCR, ELISA and Western blotting. Results: Increased CLU expression was observed in tracheal aspirates from babies with bronchopulmonary dysplasia or death. After hyperoxic exposure, CLU-/- mice exhibited more acute lung injury and activation of apoptotic cascades compared with wild-type (WT) mice. Further, hyperoxic conditions were a major stimulus for increased CLU expression and apoptosis in cultured human airway epithelial cells. We also observed that CLU overexpression attenuated hyperoxia- induced apoptosis in human airway epithelial cells. Conclusion: CLU has a significant protective role against pulmonary hyperoxic injury and their expression is related to the cell survival or protection of oxidant injury and cell death.
정한결(Han Gyul Jeong),김정민(Jung Min Kim),박지수(Ji Soo Park) 한국데이터정보과학회 2018 한국데이터정보과학회지 Vol.29 No.2
본 연구의 목적은 대학생의 자기불일치, 사회적 지지 및 SNS 몰입경향성 간의 관계를 살펴보는 것이다. 연구 대상은 남녀 대학생 417명으로 자료 분석을 위해 SPSS win 21의 평균, 표준편차, 빈도분석, 독립표본 t-검정, Pearson의 상관관계분석, 단계적 다중회귀분석, 위계적 다중회귀분석을 실시하였다. 본 연구의 주요 결과는 다음과 같다. 첫째, 대학생의 SNS 몰입경향성을 가장 잘 예측하는 변인은 부모의 사회적 지지로 나타났다. 둘째, 부모 및 친구의 지지는 대학생의 자기불일치가 SNS 몰입경향성에 미치는 영향에 대해 조절효과를 갖는 것으로 나타났다. 셋째, 교수의 지지는 대학생의 자기불일치가 SNS 몰입경향성에 미치는 영향에 대해 조절효과를 갖지 않는 것으로 나타났다. This study aimed to explore the relationship among college students’ self-discrepancy, social support, and SNS commitment tendency. The sample population was 417 male and female college students. This date were analyzed by average, standard deviation, frequency analysis, independent sample t-test, Pearson’s correlation analysis, stepwise multiple regression and hierarchical regression analysis on SPSS Win 21.0. The main finding are as follow: First, parental support was the strongest predictor of college students’ SNS commitment tendency. Second, the support of parents and friends had a moderating effect on the relationship between self-discrepancy and SNS commitment tendency. Third, professors’ social support had no moderating effect on the relationship between self-discrepancy and SNS commitment tendency.
桂鐘秀,金潔,池善豪,金正根 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.2
The authors report a case of tuberculoma of the cerebral hemisphere, which has been excised under the operating microscope. With the references reviewed, this case is interesting one in supratentorial location.
Jong Min Kim,Eun Jung Lee,Ga Eun Cho,Kunho Bae,Ju Yeun Lee,Gyule Han,Se Woong Kang 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.5
Purpose: The aim of this study was to investigate the incidence and associated clinical factors of delayed absorption of subretinal fluid (SRF) after surgery for rhegmatogenous retinal detachment. Methods: This study involved 36 eyes of 36 consecutive patients who underwent successful surgery for rhegmatogenous retinal detachment. A complete ophthalmologic evaluation, including clinical fundus examination, optical coherence tomography, and indocyanine green angiography, was conducted before and after surgery. Delayed absorption was defined as the presence of residual concave SRF or an SRF bleb at 6 months after surgery. Clinical factors and choroidal features on indocyanine green angiography were compared according to the presence and absence of delayed absorption. Results: Eighteen of 36 eyes (50%) showed delayed absorption. Macular involvement and worse preoperative visual acuity were significantly related to the presence of delayed absorption (p = 0.001 and p = 0.034, respectively). On indocyanine green angiography, preoperative choroidal vascular hyperpermeability was noted in 70% of eyes with delayed absorption and in 14% of eyes without it (p = 0.010). Conclusions: Delayed absorption of SRF after retinal reattachment surgery was not rare, with a 50% of incidence in this study. Macula-off status was significantly related to the incidence of delayed SRF absorption, and choroidal features such as choroidal vascular hyperpermeability might be responsible in part, possibly through the resultant exudative property of choroid.