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RISS 인기검색어
- 검색키워드
- 저자 : Kunho Bae (검색결과 18 건)
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Atypical epiretinal tissue in full-thickness macular holes: pathogenic and prognostic significance
Bae, Kunho,Lee, Soo Min,Kang, Se Woong,Kim, Eung Suk,Yu, Seung-Young,Kim, Kyung Tae British Medical Association 2019 British journal of ophthalmology Vol.103 No.2
<P><B>Background</B></P><P>To elucidate the clinical characteristics of a full-thickness macular hole (FTMH) with atypical epiretinal tissue (AET), and expand the spectrum of pathogenesis of MH.</P><P><B>Methods</B></P><P>This study involved 225 consecutive eyes of 211 patients who underwent surgery for an idiopathic FTMH. Eyes were divided into two groups according to the presence of AET. Tomographic features at baseline, closure rate of the MH and visual outcomes were compared between the two groups.</P><P><B>Results</B></P><P>AET was detected in 26 (11.6%) among 225 eyes. Overall closure of the MH was noted in 92.3% of eyes with AET and 99.5% of eyes without AET at 12 months postoperatively (p=0.003). At 12 months postoperatively, the mean logarithm of the minimum angle of resolution visual acuity in eyes with and without AET was 0.38 and 0.21, respectively (p=0.046). At baseline, eyes with AET more frequently had splitting of the inner retina but fewer intact photoreceptors compared with eyes without AET (19.2% vs 2.5%, and 57.7% vs 89.9%, p<0.001, respectively).</P><P><B>Conclusions</B></P><P>The presence of AET in an FTMH was related to poorer anatomical success and less visual recovery after surgery, suggesting that AET reflects a chronic pathogenic process involving more severe damage to the foveal tissue.</P>
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Kunho Bae,Chang Ki Yoon,Eun Kyoung Lee,Jae Hyup Lee,Hyeong Gon Yu 대한검안학회 2022 Annals of optometry and contact lens Vol.21 No.4
Purpose: To investigate the frequency of optic disc hyperfluorescence (ODH) and their association with macular and optic nerve head thickness in patients with active uveitis. Methods: This retrospective cross-sectional study included 37 eyes of 30 patients with active noninfectious uveitis who underwent spectral domain-optical coherence tomography (OCT) and fluorescein angiography. OCT parameters were compared between baseline and post-treatment according to the ODH. Results: ODH was observed clearly in 22 eyes (64.7%) and equivocally in five eyes (14.7%) at baseline. In subgroup analysis without clinically significant optic disc edema, central subfield thickness, peripapillary retinal nerve fiber layer thickness, disc rim area, and disc area were 262.2 μm, 110.9 μm, 1.49 mm2, and 2.02 mm2 at baseline and significantly decreased after treatment (249.5 μm, 102.1 μm, 1.34 mm2, and 1.95 mm2, respectively) in eyes with ODH (p = 0.044, p < 0.001, p = 0.001, p = 0.024, respectively). However, there was no significant changes in the eyes without ODH (all p > 0.05). Conclusions: There was a difference in the thickness reduction of the macula and optic nerve head according to the ODH. Baseline ODH should be regarded as a sign of ocular inflammation and carefully monitored.
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Deep Learning-based Prediction of Axial Length Using Ultra-widefield Fundus Photography
Richul Oh(Richul Oh),Eun Kyoung Lee(Eun Kyoung Lee),Kunho Bae(Kunho Bae),Un Chul Park(Un Chul Park),Hyeong Gon Yu(Hyeong Gon Yu),Chang Ki Yoon(Chang Ki Yoon) 대한안과학회 2023 Korean Journal of Ophthalmology Vol.37 No.2
Purpose: To develop a deep learning model that can predict the axial lengths of eyes using ultra-widefield (UWF) fundus photography. Methods: We retrospectively enrolled patients who visited the ophthalmology clinic at the Seoul National University Hospitalbetween September 2018 and December 2021. Patients with axial length measurements and UWF images taken within 3months of axial length measurement were included in the study. The dataset was divided into a development set and a testset at an 8:2 ratio while maintaining an equal distribution of axial lengths (stratified splitting with binning). We used transferlearning-based on EfficientNet B3 to develop the model. We evaluated the model’s performance using mean absolute error(MAE), R-squared (R2), and 95% confidence intervals (CIs). We used vanilla gradient saliency maps to illustrate the regions predominantlyused by convolutional neural network. Results: In total, 8,657 UWF retinal fundus images from 3,829 patients (mean age, 63.98 ±15.25 years) were included in thestudy. The deep learning model predicted the axial lengths of the test dataset with MAE and R2 values of 0.744 mm (95% CI,0.709-0.779 mm) and 0.815 (95% CI, 0.785-0.840), respectively. The model’s accuracy was 73.7%, 95.9%, and 99.2% in prediction,with error margins of ±1.0, ±2.0, and ±3.0 mm, respectively. Conclusions: We developed a deep learning-based model for predicting the axial length from UWF images with good performance.
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Lee, Kunho,Kang, Juhyun,Lee, Jaeseok,Lee, Sanghun,Bae, Joongmyeon Pergamon Press 2018 International journal of hydrogen energy Vol.43 No.7
<P><B>Abstract</B></P> <P>The objective of this study is to evaluate metal-supported solid oxide fuel cells fabricated at low temperatures (∼1000 °C) in oxidizing environments using wet chemical coating processes and a catalyst impregnation method. Typically, applying general wet chemical coating processes and heat treatment at low temperature is desirable for fabricating metal-supported solid oxide fuel cells when considering manufacturing productivity and efficiency. However, in the case of conventional anodes, a well-organized structure for high performance is rarely formed by sintering at low temperatures when using general fabrication processes. For this reason, a catalyst-impregnated anode is designed and applied to overcome the above issue. First, to evaluate the electrochemical performance of the designed anode, the area-specific resistances of half-cells are investigated. Then, the newly designed anode is applied to a single cell, and microstructural analysis and electrochemical performance measurements are performed. These results confirm that the catalysts are well distributed, that the electrolyte is fully dense and that the electrochemical performances are reasonable. Additionally, the high durability is also verified through a long-term test over 1000 h. Finally, the metal-supported solid oxide fuel cell with a catalyst-impregnated anode fabricated at low temperature is completely validated through the evaluation of a large-size single cell.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ni-impregnated LST-GDC anode fabricated at low temperature was investigated. </LI> <LI> MS-SOFCs were fabricated in oxidizing environments at low sintering temperatures. </LI> <LI> MS-SOFCs were fabricated using conventional wet chemical coating processes. </LI> <LI> The fabricated MS-SOFCs showed reasonable performances, OCVs and durability. </LI> <LI> Large-size MS-SOFC cell was successfully fabricated and evaluated. </LI> </UL> </P>
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Lee, Kunho,Kang, Juhyun,Jin, Sangbeom,Lee, Sanghun,Bae, Joongmyeon Elsevier 2017 INTERNATIONAL JOURNAL OF HYDROGEN ENERGY - Vol.42 No.9
<P><B>Abstract</B></P> <P>This paper presents a study on a solution coating process for depositing layers on porous surfaces, i.e., metal-supported SOFC electrolyte. PVP and nanoparticles are used to achieve the study objectives. PVP, which possesses a type of coiled long chain structure, can increase the solution viscosity and relieve stress. However, PVP can react with nitrate ions, consequently generating excessive ignition, which causes an inhomogeneous microstructure and forms many defects. The application of nanoparticles can control the stress and reduce cracks. Subsequently, to densify and repair the cracks, an additional solution coating process is applied. YSZ is selected as a candidate, and OCV and SEM measurements are conducted to confirm the YSZ density. The YSZ solution is multi-coated to the GDC layer, and a fully dense layer can be deposited on the coated GDC surface. The proposed coating process can fabricate a dense electrolyte under oxidation environments at a relatively low temperature using a wet-chemical process. Furthermore, in terms of spin coating and heat treatment, it can be continuously and automatically performed. Therefore, the multi-coating process developed in this research can be readily commercialized.</P> <P><B>Highlights</B></P> <P> <UL> <LI> To deposit dense layer on rigid porous surface, sol–gel coating was investigated. </LI> <LI> PVP, nanoparticles, and multi-coating process were applied. </LI> <LI> GDC modified by PVP and nanoparticles could be deposited on porous surface. </LI> <LI> YSZ solution was also investigated to improve density of GDC layer. </LI> <LI> The YSZ solution multi-coated GDC layer was fully dense. </LI> </UL> </P>
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Lee, Kunho,Yoon, Byoungyoung,Kang, Juhyun,Lee, Sanghun,Bae, Joongmyeon Elsevier 2017 International journal of hydrogen energy Vol.42 No.49
<P><B>Abstract</B></P> <P>To suppress vaporization of Cr oxides from the metallic interconnects of solid oxide fuel cells, studies on ceramic coating materials have been widely conducted. Among the studied materials, Mn-Co spinel has been a point of focus because of its benign reaction with metal substrates. This paper presents the evaluation results for a modified Mn-Co spinel. Ag was selected as a dopant for Mn-Co spinel, and various experiments were carried out to investigate the suitability of the doped spinel as an interconnect coating material. First, the lattice parameters were demonstrated to be stably maintained even though the Ag dopant is a precious metal. Second, the electrical conductivity was confirmed to be increased upon doping, and the thermal expansion coefficient of the doped material well matched that of AISI444. Third, through long-term oxidation and single-cell tests, the Ag-doped Mn-Co spinel was shown to be a useful coating material for compatible metallic interconnects in solid oxide fuel cell cathodes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ag can be doped into Mn-Co spinel, and the resultant material shows high electrical conductivity. </LI> <LI> A long-term stability test shows that Ag-doped Mn-Co can effectively prevent metal oxidation. </LI> <LI> Ag-doped Mn-Co can successfully protect cathode triple phase boundaries against Cr deposition. </LI> </UL> </P>
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용액공정기반 금속지지체형 고체산화물 연료전지의 열기계적 특성에 관한 연구
이재석(Jaeseok Lee),이건호(Kunho Lee),배중면(Joongmyeon Bae) 대한기계학회 2018 대한기계학회 춘추학술대회 Vol.2018 No.12
To be applied to portable and transportation fields, metal-supported solid oxide fuel cell (MS-SOFC) requires not only high electrochemical performance and durability but also high volumetric and gravimetric power density. However, reducing the thickness of the metal substrate to achieve higher volumetric and gravimetric power density may cause thermomechanical deformation of the cell during the heat treatment processes. In this study, thermomechanical characteristics of the wet-chemical process based MS-SOFC, especially utilized a thin metal substrate (~ 100 μm), were investigated. Firstly, thermal surface stresses generated during the wet-chemical processes and the thermomechanical deformation caused by the thermal surface stresses were measured by thermomechanical analysis and surface profiler, respectively. Furthermore, a novel method of introducing magnets in the wet-chemical processes to suppress the thermomechanical deformation was proposed and evaluated. As a result, thermomechanical deformation of the MS-SOFC was successfully suppressed from approximately 160 μm to 30 μm without significant defects of the thin film electrolyte such as cracks, pinholes, or residual stresses.
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