Factors associated with the risk of colorectal neoplasia in young adults under age 40

Ilsoo Kim,Han Hee Lee,Young Jae Ko,Ho Eun Chang,Dae Young Cheung,Bo-In Lee,Young-Seok Cho,Jin Il Kim,Myung-Gyu Choi 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.5

Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal neoplasia (CRN). Methods: A cross-sectional analysis was performed for individuals younger than 40 years who underwent colonoscopy in Seoul St. Mary’s Hospital and its affiliated health screening center. High-risk CRN was defined as adenoma or sessile serrated lesion ≥ 10 mm, with three or more adenomas, villous histology, high grade dysplasia, or carcinoma. Results: Of these 13,621 included participants, 2,023 (14.9%) had one and more CRN. Young patients with CRN tended to be elderly, male, obese, smoker, having a habit of drinking, and having comorbidities such as hypertension, dyslipidemia, diabetes, and chronic kidney disease. In a multivariate analysis adjusted for age, sex, obesity, smoking status, and alcohol intake, old age (odds ratio [OR], 1.086; 95% confidence interval [CI], 1.054 to 1.119), male sex (OR, 1.748; 95% CI, 1.247 to 2.451), obesity (OR, 1.439; 95% CI, 1.133 to 1.828), and smoking (OR, 1.654; 95% CI, 1.287 to 2.127) were independent risk factors for overall CRN. Obesity and smoking as two modifiable factors increased the risk for high-risk CRN even more than for overall CRN (OR, 1.734; 95% CI, 1.168 to 2.575 and OR, 1.797; 95% CI, 1.172 to 2.753, respectively). Conclusions: Obesity and smoking were modifiable risk factors for CRN in young adults. They increased the risk for highrisk CRN even more than for overall CRN. A colonoscopy might be beneficial for young individuals with these factors.

영골(靈骨).강압혈(降壓穴) 자극(刺鍼)이 혈압(血壓)에 미치는 영향(影向)

임영남,심성용,한지완,고호연,박종형,한양희,전찬용,김동우,Yim, Young-Nam,Sim, Sung-Yong,Han, Ji-Wan,Ko, Ho-Yeon,Park, Chong-Hyeong,Han, Yang-Hee,Chun, Chan-Yong,Kim, Dong-Woo 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

Objective : The purpose of this study is to evaluate the clinical effect of the non-pharmacological anti-hypertension method, acupuncture, for hypertensive patients. Methods : 26 patients diagnosed with hypertension were each treated by one of three methods: an anti-hypertension drug(adalat soft capsule), venepuncture, and acupuncture. In cases of rising blood pressure, patients were treated by their one of the three methods, and blood pressure was measured at regular intervals. Result : As for the group of acupuncture treated patients on Young-gol(ling-gu) and Gang-ap-hyul(jiang-ya-xue), readings dropped 18.0mmHg in systolic blood pressure and 6.50mmHg in diastolic blood pressure. This was a greater effect than that seen in the venepuncture treated patients. Blood pressure checked one hour after acupuncture treatment showed a greater difference than blood pressure checked after thirty minutes. Conclusion : Safe reductions in blood pressure were observed through the non-pharmacological method of acupuncture on Young-gol(ling-gu) and Gang-ap-hyul(Jiang-ya-xue).

법랑질 접착에 대한 습윤 효과

고근호,조영곤,진철희,유상훈,김종욱,박병철,기영재,최희영,김종진 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.3

This study evaluated the microleakage and interfacial gap between enamel and composite resin under the dry and wet condition of the enamel surface, V shaped class 5 cavities were prepared on the occlusal portion of extracted human molars. Samples were divided into three groups: D group (air dry for 10-15s), BD group (blot dry with moist cotton pellet), and DR group (air dry for 10-15s and rewet with Aqua-Prep F for 20s). Cavities were filled using Aelitefil composite resin after applied One-Step. Microleakage was tested by 2% methylene blue dye solution and the data were statistically analysed by Kruskal-Wallis test and Mann-Whitney test. Also Enamel-resin interface was observed under SEM. Group BD showed statistically lower microleakage than group D (p〈0.05). but there was no statistically significant difference between group BD and DR (p)0.05). At the enamel-resin interface, group D showed the gap of 2 ㎛ thickness, but group BD and DR showed close adaptation. In conclusion, the use of blot dry and rewetting agent (Aqua-Prep F) resulted in decreased microleakage and improved adhesion between enamel and resin when using One-Step.

활동치료학과 교육과정 개발 연구

양광희,고영애,조희,양선희,안은숙,전미영 적십자간호전문대학 2000 적십자간호전문대학논문집 Vol.22 No.-

심한 골병변으로 발현된 기능성 낭종성 부갑상선 선종

전숙,김영희,박지영,고관표,박철영,김덕윤,우정택,김성운,김진우,김영설,고석환 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.2

낭종성 부갑상선 선종과 심한 골병변을 동반한 부갑상선 기능항진증은 매우 드문 질환으로서, 저자들은 양측 고관절의 통증을 초기 주소로 내원한 환자에서 고칼슘혈증과 부갑상선 호르몬 증가, 골병변의 방사선적 소견을 통해 부갑상선 기능항진증을 진단하고, 경부 초음파와 컴퓨터 단층 촬영, 부갑상선 스캔검사 및 수술중 부갑상선 낭종액 검사 등을 통해 기능성 부갑상선 낭종의 한 종류인 낭종성 부갑상선 선종을 진단하고 수술적 제거를 통하여 정상화된 1예를 경험하였다. A cystic parathyroid adenoma is rare. A case of primary hyperparathyroidism, with the cystic formation of a parathyroid adenoma and a severe bony lesion, is reported. A 52-year-old male was admitted due to pain in both hips and for evaluation of hypercalcemia. The plasma level of the intact parathyroid hormone (iPTH) was elevated to 1424 pg/mL. Ultrasonography and the computed tomography revealed a parathyroid cyst on the left thyroid lower pole. Parathyroid scintigraphy detected a parathyroid adenoma. A radiograph showed a subperiosteal bone resorption on the phalanges, and a brown tumor (osteitis fibrosa cystica) on the femur shaft was noted. A surgical excision of the parathyroid adenoma was performed. The PTH level in the cystic fluid was increased. A histological examination confirmed a cystic parathyroid adenoma. The PTH level was normalized after the operation (J Kor SOC Endocrinol 18:214-220, 2003).

敎授一學習過程의 Feedback의 效果 檢證에 關한 硏究 : Minnis와 Shrable의 知的 水準分析 相互作用 模型을 通한 問答技術 訓練을 中心으로

高永喜 仁川敎育大學校 1972 論文集 Vol.7 No.2

敎授一學習 過程의 feedbabk이 敎搜一學習 方法을 改善하고 學生들의 學業成績을 높힐 수 있다는 假定下에 問答技術의 訓練과 그 效果 檢證으로 敎帥의 敎搜技術의 向上方案과 敎帥養成 및 現職敎帥을 再敎育위한 Program의 資料를 얻기 爲한 目的으로 Minnis과 Shrable의 問答過程 分析模型과 이를 우리나라 實情에 適合하도록 修正한 금 宗西의 模型을 通해서 問答技術을 訓練하였으며 本 硏究의 假說은 다음과 같다. <假說Ⅰ> 敎授一學習 過程에서 問答技術을 訓練받은 敎帥는 訓練받지 않은 敎帥보다 生産的 問答技術을 보일 것이다. <假說Ⅱ> 問答技術을 訓練받은 敎師의 學級 兒童의 學業成績은 訓練받지 않은 敎師의 學級 兒童의 學業成績보다 더 높을 것이다. 硏究方法은 實驗硏究로써 서울시내 「가級 國民學校 敎師 30名을 名 5名씩 無選標集하여 問答技術의 訓練을 쌓은 實驗集團과 訓練하지 않는 比較集團으로 두 集團間의 敎授技術(問答過程의 問答比, 推論 適用比, 水準 變化比, 學生 發言比)과 對象學級의 兒童들의 學業成就程度를 t 혹은 CR 檢證하였다. 硏究의 結果는 假說檢證으로 處理하였으며 그 結果는 다음과 같다. <假說Ⅰ>은 水準 變化比를 除外하고는 肯定되었다. ① 두 集團間의 問答比는 P<0.05로 5% 水準에서 實驗集團이 더 높았다. ② 두 集團間의 推論 適用比는 P<0.05로 5% 水準에서 實驗集團이 더 높았다. ③ 두 集團間의 水準 變化比는 差가 없었다. ④ 두 集團間의 學生 發言比는 P<0.02로 2% 수준에서 實驗集團이 더 높았다. <假說Ⅱ>는 全體, 社會, 自然科目에 있어서는 肯定되었으나 國語와 算數科目은 否定되었다. ① 두 集團間의 全體 社會 自然科目 學力檢査의 結果는 P<0.01로 1% 水準에서 퍽 意義있는 差로서 實驗集團이 더 높았다. ② 두 集團間의 國語 算數科 學力檢査의 結果는 差가 없었다.

갈륨합금과 아말감의 전기화학적 부식거동 비교

고영무,최한철,강성남,강희영,이승윤 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.3

A gallium based alloy(GA) that was developed as a substitute for dental amalgam was investigated for electrochemical corrosion behavior in 4 kinds of electrolytes(1% lactic acid, 0.05% HCI, Modified Fusayama's artificial saliva, and 0.9% NaCl). The related corroded microstructure were examined and microanalyses were conducted using ICPES. Polarization tests were conducted by scanning from -1,500㎷ to 1,000㎷(vs.SCE) at 75㎷/min. The obtained results were as follows: 1. GA showed wide passivation area next to SYB in artificial saliva, suggesting good stability. 2. The amounts of Sn, Cu released from GA were similiar to those of CAV, and decreased in the order of KAT, SYB. 3. All of specimens were observed pits at the area of pores in electrolytes containing chloride ions, and forming much corrosion products in 1% lactic acid and artificial saliva after corrosion test. 4. From the surface analyses of XRD, GA showed much corosion products containing gallium at the surface after corrosion test. In conclusion, the corrosion resistance of GA was lower than that of SYB and similiar to that of CAV and KAT.

말더듬 아동과 일반 아동의 유창성 특성 비교

고영옥,전희숙,권도하 대구대학교 특수교육재활과학연구소 2007 再活科學硏究 Vol.25 No.2

The purpose of this study was to investigate characteristics of stutter children on the speech task. The speech task was automatic speech, reading, and monologue. we collect speech sampling during of task. In the study participated seven stuttering children of 7 to 12years old(4 males, 3 females) and seven nonstuttering children(5 males, 2 females). The results of this study were as following. First, there was not significant difference between stuttering children and nonstuttering in the articulation rate. On the automatic speech task, stuttering children articulation rate was mean 171.60(SPM) and nonstuttering children articulation rate was mean 168.34(SPM). On the reading task, stuttering children articulation rate was mean 225.82(SPM) and nonstuttering children articulation rate was mean 218.09(SPM). On the monologue task, stuttering children articulation rate was mean 195.58(SPM) and nonstuttering children articulation rate was mean 191.95(SPM). Second, In the stutter children, dysfluency syllable number varied on the speech task. Also, stutter children, dysfluency syllable rate varied on the speech task. On the automatic, monologue task, dysfluency syllable number was mean 8.57syllable (SD=9.71), 20.71syllable (SD=13.47). On the automatic, monologue task, dysfluency syllable rate was mean 15.85%(SD=32.98), 29.00%(SD=19.74). 본 연구의 목적은 말더듬 아동이 각기 다른 구어 과업에서 유창하게 말할 때의 구어 특성을 알아보는 것이었다. 본 연구의 대상은 7~12세의 말더듬 아동 7명(남자 4명, 여자 3명)과 일반 아동7명(남자 5명, 여자 2명)이었다. 자동구어와 독백 과업을 실시하는 동안 구어샘플 수집하였다. 연구의 결과는 다음과 같다. 첫째, 말더듬 아동과 일반 아동의 유창한 구어의 속도에는 차이는 없었다. 자동구어 및 독백 과업 모두 유의한 차이가 없었다. 둘째, 과업별 말더듬 아동의 비유창한 음절수는 구어과업에 따라 다양하게 나타났다. 그리고 비유창한 음절 비율도 구어과업에 따라 다양하게 나타났다. 자동구어, 읽기, 독백과업에서 말더듬 아동의 비유창한 음절수는 평균 8.57음절(SD=9.71), 27.57음절(SD=23.47), 20.71음절(SD=13.47)이었다. 비유창한 음절비율은 자동구어, 독백과업에서 평균 15.85%(SD=32.98), 61.35%(SD=106.08), 29.00%(SD=19.74)이었다.

일상생활에서 겪는 고등학생의 스트레스요인과 대처방식에 관한 연구

고희숙,민현숙,정영숙 충북대학교 교육·생활연구소 1999 생활과학연구논총 Vol.2 No.-

The purpose of this study is to investigate the daily stressors of human relations, emotional lives, and economic lives which high school students go through and their coping strategies about these stressors, to provide the necessary materials and useful information for guiding students and educating their parents. The research questions of this study are: (1) the stressors of the male and female students in the general high school and their coping strategies, (2) the stressors of the high students according to the both sexes and their coping strategies, (3) the correlation between the stressors of high school students and their coping strategies. The subjects of this study consist of 320 students from a boys' high school and a girls' high school and 320 students from a coeducational high school. The test instruments used for this study can be divided into two categories; the test for measuring the stressors consisted of 75 items (7 subcategories) and the test for measuring the coping strategies consisted of 40 items. The data were analyzed by frequency distribution, percent, mean score, standard deviation, t-test, and simple correlation analysis. The main conclusions of this study were as follows: 1) When it comes to the stressors, students showed some differences depending on their sex. In terms of the relation between friends, male students have gone through more stresses than female students. 2) In terms of their coping strategies, male students from the boys' high school were shown to use more logical analysis strategies than those from the coeducational high school, male students from the coeducational high school usually used more receptive resignation strategies than those from the boys' high school, and also female students from the coeducational high school tended to employ more problem-solving and emotional discharge strategies than those from the girls' high schools. 3) The stressors vary depending on their sex. Male students have used more logical analysis, affirmative reevaluation, guide/support strategies, (which belong to the accessible coping strategies) and cognitive avoidance, emotional discharge strategies, (which are examples of avoidant coping strategies) than female students.4) As to the correlation between high school students' stressors and their coping strategies, it was shown that the correlation between stressors and logical analysis, affirmative reevaluation, and guide/support, problem-solving strategies (they all belong to accessible coping strategies) was higher than anything else.

상악확장술 치료효과의 메타분석 : 견치간 폭경과 대구치간 폭경 확장의 비교 및 급속과 완속 확장의 비교 comparison of intercanine/intermolar expansion and rapid/slow expansion

고창희,임성훈,윤영주,김광원 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.1

본 연구의 목적은 다수의 연구들로부터 추출한 각각의 결과를 체계적이고 객관적인 방법으로 병합, 개관하는 통계분석법인 메타분석을 이용하여 상악확장술에서의 견치간 폭경과 대구치간 폭경의 확장 및 급속과 완속 확장에서의 확장량과 재발량을 비교하는 것이었다. 메드라인 검색을 통해 1979년부터 2000년까지의 문헌들 중 사람을 대상으로 상악확장술의 효과에 관해 조사한 문헌 388개를 찾은 후 논문 선택 및 제외 범주에 따라 최종적으로 7개의 문헌을선정하여 메타분석을 시행하여 다음과 같은 결과를 얻었다. 1. 상악확장술에 의한 상악 제 1대구치간 폭경은 평균 6.0mm의 확장되었으며, 보정 후 측정에서 평균4.8mm가 유지되어 평균 20.0%(1.2mm)의 재발경향을 보였다. 2. 상악 견치간 폭경은 제 1대구치간 폭경의 확장보다 2.3mm적은 평균 3.7mm 확장되었으며, 보정 후 측정에서 평균 2.6mm가 유지되어 평균 29.7%(1.1mm)의 재발경향을 보였다. 3. 급속 상악확장술과 완속 상악확장술의 치료효과의 차이는 확장량과 보정 후 재발량 및 유지량에서 6% 미만(0.1-0.3mm)이었다. 그러나 상악 견치간 및 제1대구치간 폭경 변화에 있어서 두 방법 간에 골격성 및 치성 확장량의 비율에서 차이가 있을 수 있다. As a research method that weighs and combines evidence, meta analysis produces evidence that is more powerful than the original studies. The purpose of this study was to compare the intercanine/intermolar expansion and rapid/slow expansion in the maxillary expansion treatment using meta analysis. Medline was searched from 1979 to 2000 for all studies examining the stability of transverse expansion of the human maxilla, and 388 articles were found. Then these articles were reduced to 7 based on the defined inclusion and exclusion criteria, and a cumulative Meta evaluation score was computed for each study. The results were as follows; 1. The mean expansion in intermolar width was 6.0mm. Of the 6.0mm, 4.8mm was retained and 20.0%(1.2mm) was relapsed while wearing retainers. 2. In intercanines width, the mean expansion was 3.7mm. Of the 3.7mm, 2.6mm was retained and 29.7%(1.1mm) was relapsed while wearing retainers. 3. The differences in the amount of expansion and relapse between rapid expansion group and slow expansion group were less than 6%(0.1-0.3mm). But, there might be differences in the skeletal/dental exapnsion ratios according to the expansion method.