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Factors associated with the risk of colorectal neoplasia in young adults under age 40
Ilsoo Kim,Han Hee Lee,Young Jae Ko,Ho Eun Chang,Dae Young Cheung,Bo-In Lee,Young-Seok Cho,Jin Il Kim,Myung-Gyu Choi 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.5
Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal neoplasia (CRN). Methods: A cross-sectional analysis was performed for individuals younger than 40 years who underwent colonoscopy in Seoul St. Mary’s Hospital and its affiliated health screening center. High-risk CRN was defined as adenoma or sessile serrated lesion ≥ 10 mm, with three or more adenomas, villous histology, high grade dysplasia, or carcinoma. Results: Of these 13,621 included participants, 2,023 (14.9%) had one and more CRN. Young patients with CRN tended to be elderly, male, obese, smoker, having a habit of drinking, and having comorbidities such as hypertension, dyslipidemia, diabetes, and chronic kidney disease. In a multivariate analysis adjusted for age, sex, obesity, smoking status, and alcohol intake, old age (odds ratio [OR], 1.086; 95% confidence interval [CI], 1.054 to 1.119), male sex (OR, 1.748; 95% CI, 1.247 to 2.451), obesity (OR, 1.439; 95% CI, 1.133 to 1.828), and smoking (OR, 1.654; 95% CI, 1.287 to 2.127) were independent risk factors for overall CRN. Obesity and smoking as two modifiable factors increased the risk for high-risk CRN even more than for overall CRN (OR, 1.734; 95% CI, 1.168 to 2.575 and OR, 1.797; 95% CI, 1.172 to 2.753, respectively). Conclusions: Obesity and smoking were modifiable risk factors for CRN in young adults. They increased the risk for highrisk CRN even more than for overall CRN. A colonoscopy might be beneficial for young individuals with these factors.
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고영민,이내우,최재욱,우희철,신학기 한국산업안전학회 2002 한국안전학회지 Vol.17 No.1
Among the disposal techniques of inorganic wastewater sludges from industries, most of sludges were dealed with buring underground inefficiently. But we have tried to recycle the resources that exhausted inorganic sludges were properly blended to certain ratioes to make lightweight aggregate, that means manufacturing of it can be possible through blending of various components, drying, sintering, cooling and crushing to certain sizes that are needed by consumers. As disposal method of inorganic wastewater sludge is changed to environmentally fraternative method, this method could be very useful to make lightweight aggregates for decoration of building and the other so many purposes of those usages. That could be economically useful due to expected income for buring costs of ordinary disposal method from industries and sales income after manufacturing it. The second important profit is saving foreign currency from purchasing self-developed lightweight aggregate instead of importing expensive foreign product. This product will be also very impressive to user because of the fraternative lightweight to be composed of apatite structure that is important part of human body.
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고영환,김재하 제주대학교 방사능이용연구소 2001 연구보고 Vol.15 No.-
방사선 照射가 한라봉 감귤의 저장에 미치는 영향을 조사하였다. 한라봉 신선과일에 Cobalt 60으로 감마선을 0 kGy, 1 kGy, 2 kGy 그리고 3kGy를 각각 조사하여 실온 및 저온(6℃)에 저장하였다. 저장중의 부패율, 중량 변화, pH, 가용성고형분을 측정하였고, 부패와 관련된 미생물을 분리 동정하였다. 저온저장이 실온저장보다 부패방지와 갈변억제에 보다 더 효과적었다. 방사선을 조사하지 아니한 처리구나 1kGy 조사한 처리구에 비해서, 2 kGy이상 γ-방사선을 조사한 처리구는 부패와 갈변 정도가 심하였다. 저장 중에 감귤의 부패와 관련하여 나타나는 미생물은 대부분이 Penicillium 속이었다. 저온 저장했을 때가 실온 저장했을때보다 중량감소율이 더 낮았다. 또한 γ선을 2kGy 이상 조사했을 경우에는 상대적으로 중량감소가 크게 나타났다. 저장 중에 감귤의 pH와 당도는 저장기간이 경과함에 따라서 전반적으로 증가하는 경향이었다. 이러한 경향은 실온저장과 저온저장 그리고 방사선 조사구와 비조사구간에는 별다른 차이가 없었다. 전반적으로 γ 방사선을 2kGy 이상 조사하면, 감귤의 저장에 부정적인 효과가 나타났으며, 1 kGy 조사한 처리구와 방사선을 조사하지 아니한 대조구 간에는 유의적인 차이가 인정되지 않았다. 따라서, 감귤의 저장에는 방사선 조사선량을 1 kGy이하로 하는 것이 바람직하다. Effects of γ-ray irradiation on storage of citrus orange Halabong were investigated. γ-Ray was irradiated on fresh fruits of Halabong on the levels of 0 kGy, 1 kGy and 3 kGy using cobalt 60 as a radiation source. Irradiated fruits were stored at room or cold(6℃) temperatures for storage. During storage, changes in decay, weight , pH and soluble solids were monitored timewisely, and molds related with fruit decay were isolated and purified. Storage at cold temperature was more effective against decay and browning. The pretreated fruits with higher dose radiation than 2 kGy showed severe decay and browning. Most of the molds associated with fruit decay were Penicillium species. Weight loss during cold storage was less than that during room temperature storage. And irradiation of fruits with higher dose radiation than 2 kGy gave higher weight loss. Soluble solid content and pH of juice increased on the whole as the storage time went by. This tendency was all similar in every cases of fruit storage whether stored at room temperature or cold temperature regardless of γ-ray irradiation. In conclusion, higher dose radiation than 2 kGy resulted in negative effective on fruit storage, and no significant difference on the whole was observed between non-irradiated fruits and 1 kGy-irradiated fruits. It is highly recommended that citrus orange Halabong should be irradiated with lower dose of radiation than 1 kGy when necessary.
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고영인,임재택,조희숙,황해익,정계숙 부산대학교 영유아보육연구소 1998 영유아보육연구 Vol.4 No.-
The purpose of this study was to investigate longitudinal growth and development of young children and follow-up effects of the educare program in the PNU Day Care Center. Particularly, the first objective of this second report of study was the comparison the entire domains of development with age between the Oct. of 1995 and the Dec. of 1998. The second objective was to analyze the developmental .changes of 5 children who entered the center in 4 years old since Oct. 1995. The subjects of this study were 448 children(241 boys, 207 girls). The instruments of this study were the KISC and KEDl-WISC(for intelligence test), the Learning Readiness Test, the Social and Emotional Scale, Height Scale and Weight Scale( for physical growth). The tests were carried out 2 times per year (the early of the year and the late of the year). Results from comparsion across the 1st through 7th tests during 3 years indicated that the mean of the height was increased about 1-8cm for all of 2-5 years old children. The mean of the weight also was increased about 1.5-4.0kg except 2 years old children. The intelligence score (T score) by KISC was increased around 6-42 points except 6 years old boys and girls. In the intelligence score by KEDl, there was improvements of average 8 points for 7 years old children. In the learning Readiness Test of 5, 6 years old children, the scores all of children except 6 years old girls got were decreased. The scores of 6 years old girls were incresed 6 points in the Dec. of 1998. In the Social and Emotional Scale, there was big improvement of scores between in the 1st test and in the 7th test. These results were discussed in the view of sample size, developmental characteristics, test instruments and educare program of the PNU day care center.
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고근호,조영곤,진철희,유상훈,김종욱,박병철,기영재,최희영,김종진 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.3
This study evaluated the microleakage and interfacial gap between enamel and composite resin under the dry and wet condition of the enamel surface, V shaped class 5 cavities were prepared on the occlusal portion of extracted human molars. Samples were divided into three groups: D group (air dry for 10-15s), BD group (blot dry with moist cotton pellet), and DR group (air dry for 10-15s and rewet with Aqua-Prep F for 20s). Cavities were filled using Aelitefil composite resin after applied One-Step. Microleakage was tested by 2% methylene blue dye solution and the data were statistically analysed by Kruskal-Wallis test and Mann-Whitney test. Also Enamel-resin interface was observed under SEM. Group BD showed statistically lower microleakage than group D (p〈0.05). but there was no statistically significant difference between group BD and DR (p)0.05). At the enamel-resin interface, group D showed the gap of 2 ㎛ thickness, but group BD and DR showed close adaptation. In conclusion, the use of blot dry and rewetting agent (Aqua-Prep F) resulted in decreased microleakage and improved adhesion between enamel and resin when using One-Step.
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