척수압박으로 발현된 급성 골수성 백혈병에 동반된 과립구성 육종 1 례

윤상준,김영곤,김희종,박유환,정춘해,김양수,김태균,박영진,전호종 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

저자들은 척수압박으로 하지마비를 보인 환자에서 수술 후에 급성 백혈병에 동반된 과립구성 육종으로 진단된 환자 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Granulocytic sarcoma(GS) is an uncommon tumor composed of immature cells of the granulocytic series. Most case of GS occur in the course of acute leukemia and the blast crisis of chronic leukemia, Rarely, however, it may present before leukemia becomes clinically apparent. It may also occur in patients with myeloproliferative disoders. GS has been reported that it occurs in 3% to 9% of patients with acute myelogenous leukemia(AML) and the incidence of GS is reported to be higher in patients with t(8;21). GS occurs relatively commonly in africa and has been reported to affect 10-25% of black children presenting with AML. This is very rare case of granulocytic sarcoma with AML(FAB M5) presented with spinal cord compression which was supported by decompression laminectomy.

TFC을 이용한 하부 요추골에서 후방 추체간 융합술

윤승환,조준,문창택,장상근 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

To determine which factors influence the successful results in the patients who underwent lumbar arthrodesis with TFC(threaded fusion cage) at L34 to L5S1 intervertebral space. 20 subjects were analysed in retrospective method. Between January 1997 and April 1998, interbody fusion with TFC was undergone on 20 patients, and among them, 19 patients(95% ) were confirmed to have bone fusion at 12 months after operation. All patients were classified into group A(satisfactory results) and group B(unsatisfactory results) according to comprehensive low back questionnaires from their answer. They were checked with reference to intervertebral disc height and scoliotic, and lordotic angle with Cobb's method in the anterioposterior and lateral lumbar spine films before/after operation, and TFC diameter and length were categorized. In group A, 11 cases(55%) of "excellent" results and 5 cases(25%) of "good" results were included. In group B, 2 cases(10%) of "fair" results and 2 cases (10%) of "poor" results were included. In the lateral projection of group A and B. the mean preoperative disc height were 9.88±2.69mm and 10.45±2.39mm. Twelve months after operation, the mean disc height of group A was significantly increased to 14.11±2.14mm, but that in group B was not significantly increased only to 11.50±2.52mm. Preoperatively, the measured scoliotic and lordotic angles between L1 and S1 by Cobb's method were similar in both groups, being 4.18±3.58 and 26.75±6.64 degree in the group A, 3.50±2.65 and 33.25± 13.10 degreee in the group B. Twelve months after operation, the angles for group A were significantly improved to 0 and 48.13±11.83 degree, but in group B, not changed into 4.50±4.79 and 33.75±10.31 degree. The mean diameter and length of TFC in group A were, in each, 15.62± 1.09mm and 24.44±2.39mm but, 12.50±1.00mm and 21.00±0.00mm in those of group B. For successful results after TFC interbody fusion in the lower lumbar spine, recovery of narrow disc space, scoliosis, lordosis accompanied by solid arthrodesis were necessary. The authors propose that relatively larger-sized TFC should be profitable for those cases.

요추부 수술후 통증관리를 위하여 실시한 Morphine Sulfate를 이용한 Caudal Block의 효과

윤승환,박형천,김은영,전병윤,이홍식,이성근 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.6

뇌 실질 출혈이 동반된 Reye 증후군 1례

이창연,오연희,임문환,유문집,박성기,김태우 동국대학교 경주대학 1991 東國論集 Vol.10 No.-

Reye syndrome is a disorder of unknown etiology in which a child recovering form a viral prodrome suddenly develops pernicious vomiting & eventually develops neurologic changes. The syndrome is defined to acute noninflammatory encephalopathy with fatty degeneration of liver and other organs. The coagulopathy or Reye syndrome is associated with proloned PT caused by the mitochondrial injury compromising synthesis of proteins and clotting factors in liver. In this case, we observed ICH on right parietal and occipital area in brain CT. Actually, bleeding in the major organ is extremely rare in Reye syndrome, this may be the first case report of CNS bleeding in Korea associated with Reye syndrome. In addition to case report, we present a brief review of the related literatures.

ImmunoDot법에 의한 전신성 류마티스 질환의 자가항체 검사

박성환,김선준,김성일,민준기,이상헌,홍연식,조철수,김호연 최신의학사 1997 最新醫學 Vol.40 No.7

연 착화제 효능에 관한 동물실험적 연구

서병성,김준연,김정만,김용규,정갑열,김성환,김인식,김병권 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3

This experiment was carried out to compare the efficacy of 2,3-dimercaptosuccinic acid(DMSA) and calcium ethylenediamine tetraacetate(CaEDTA) as chelating agents for lead poisoning. The rats had been fed water containing 0.5% lead acetate for 3 months and randomly divided into three groups. We administered DMSA only for group I(n=5), CaEDTA only for group II(n=5), and both DMSA and CaEDTA for group III(n=10), for 4 days. We evaluated urinary lead(PbU) level, blood lead(PbB) level and blood zinc protoporphyrin(ZPP) level before and after administration of the chelating agents. The results obtained were as follows; 1. After administration of chelating agents, the mean PbU levels, which were 248.2㎍/dl, 252.6㎍/dl and 270.0㎍/dl in group I, II and III before administration, were increased to 484.6㎍/dl, 479.9㎍/dl and 1,792.1㎍/dl in group I, II and III, respectively(p<0.05). 2. After administration of chelating agents, the mean PbB levels, which were 67.4㎍/dl, 59.9㎍/dl and 62.5㎍/dl in group I, II and III before administration, were decreased to 38.1㎍/dl, 36.3㎍/dl and 31.3㎍/dl in group I, II and III, respectively(p<0.05), but there were no different changes of ZPP level among groups. 3. The blood lead clearances, which were calculated by PbB level before and after administration of chelating agents, were 49.8%, 43.5% and 39.5% in group III, I and II, respectively.

Ti첨가 및 균질화 처리가 원심주조한 Cu-Zn-Al계 고력황동의 기계적 성질에 미치는 영향

권영한,허성강,김창규,윤재홍 國立 昌原大學校 産業技術硏究所 1997 産技硏論文集 Vol.11 No.-

Effects of Ti addition and homogenizing treatment on the mechanical properties in Cu-Zn-Al system high strength brass were investigated. Grain refinement was successfully achieved by Ti addition: The microstructure, which was composed of island or fine feather-like branched Ti compounds was changed to feather-like eutectic microstructure as the content of Ti increased. The highest hardness values was obtained for 0.5wt% Ti specimen and the second was Ti non-added specimen in as-cast conditions. Maximum tensile strength was obtained for 0.5wt% Ti specimen. Dueing to the presence of cast defects and worse castability, tensile strength decreased as the content of Ti increased. Elongation was increased with increasing homogenizing time and temperature: remarkable increase was obtained for 400℃ homogenizing temperature in the 0.5wt% Ti specimen. For 500℃ and 600℃ homogenizing temperature, high elongation was obtained in 2 and 4wt% Ti specimen.

ICR계 마우스에서 홍화씨 에탄올 추출물의 급성독성시험

황윤환,박병권,임종환,김명석,송인배,명노일,정상일,윤효인 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2008 動物醫科學硏究誌 Vol.15 No.1

The present study was carried out to investigate the potential acute toxicity of safflower seed by a single oral dose in ICR mice. Twenty animals of each sex were randomly assigned to four groups of 5 rats each and were administered singly by gavage at dose levels of 0, and 2,500 mg/kg bodyweight. Mortalities, clinical findings, and body weight changes were found and complete gross postmortem examinations were performed. Throughout the study period, no treatment-related deaths were observed. There were no adverse effects in clinical signs, body weight, and gross findings at any dose tested. The results showed that the single oral administration of safflower seed did not cause any toxic effect at the dose levels of 2,500 mg/kg in rats and the minimal lethal dose was considered to be over 2,500 mg/kg body weight for both sexes.

태권도 연구경향과 방향성 대한 연구

지치환,윤상화,조임형 龍仁大學校 武道硏究所 1997 武道硏究所誌 Vol.8 No.2

The purpose of this study was to investigate the rescarch pattern and trends of Tae Kwon Do researches. Hundred ten papers were analysised for this purpose and the analysis were devided two categories. The first category was analysis of subject in Tae Kwon Do research. The second category was analysis of object in Tae Kwon Do research. From the analysis, result were made as follows; 1. Analysis of subject in Tae Kwon Do research. The researches which treat physiological factor were 26.4%, the researches which treat techniques for compitition were 25.5%, and the researches which treat psycological factors were 11.8%. 2. Analysis of object in Tae Kwon Do research. The researches which object compitition were 77.3%, and it contains kicking, physical fitness, point, athlete, division, weight, structure of technique, injury, judge, rules. The researches which object displine were 10% and reality of Tae Kwon Do were only 9%

회생용 4분할 2상 쵸퍼에 의한 회생영역의 확대

이승환,김용주,한경희,정연택,강승욱 明知大學校 産業技術硏究所 1993 産業技術硏究所論文集 Vol.12 No.-

In this paper, we proposes two phase chopper system with flour. separate groups of D.C motor for regenerative braking. The main circuit consists of four sets of chopping parts, eight diodes and four separate groups of D.C motor. Although the proposed chopper circuit requires more circuit elements than the conventional two phase chopper system with, combined output, it has the following advantages: (1) The region of regenerative braking becomes twice as that of the conventional two phase chopper system. (2)Current division of load becomes equalized. Therefore. it is possible to drive not only series motor but also shunt and separately excited motor (3) The harmonic component of the source current is greatly diminished.