혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

중년기의 스포츠 체력특성에 관한 연구

鄭升溶,崔淙洙,李鍾珏,金昌範,長鳳愚 忠北大學校 平生體育硏究所 1990 平生體育硏究所 論文集 Vol.4 No.-

The study aims to have cognizance of middle-aged mental and physiological properties by means of presenting the feature of physical strength, and to make middle-aged people try to prevent symptoms of senility and live a healthy and beneficial life for the rest of their days by means of showing a program of physical exercise suitable for middle-aged people. According to the middle-aged feature of physical strength, the decline of physical strength and physilogical function was remarkable. Individual variation in physical strength was wide and bodily organization was likely to get damaged easily as one attains an advanced age. Middle-aged people was slower in revovering and blood pressure was higher than young one after the same physical exercise. In conclusion, middle-aged people must build up his physical strength and try to prevent symptoms of senility through light physical exercises rather than heavy ones.

Capsicum chinense, 재래종 및 저항성 고추 유전자원에서 역병 저항성 계통 선발

김정훈,여승호,김동우,배수연,한정혜,황희숙,김병수 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

2000년도에 검정에서 역병에 살아남은 개체들로부터 채종하여 육성한 Capsicum chinense 31계통에 대하여 역병 저항성을 검정한 결과 고도의 저항성을 나타내는 것은 발견되지 않았다. 2001년도의 검정에서 역병에 살아남은 개체로부터 채종한 재래종 26계통에 대하여 다시 역병 저항성 검정을 실시한 결과 KC180, KC230, KC195, KC194에서 다수의 개체가 살아남아 저항성을 나타내었다. 그러나 KC180과 KC230은 각각 AC2258과 CM334와 혼종된 것으로 관찰되었다. KC195와 KC194는 재래종의 형질을 유지하고 있는 것으로 관찰되었다. CM334의 보존 증식과정에 자연교잡이 일어난 것으로 보여 이의 순도향상을 위하여 채종년도별로 시료를 꺼내어 역병저항성 검정을 실시한 결과 가장 오래된 1992년도 채종종자에서부터 약간의 이형주가 관찰도기 시작하여 1995년부터 2001년도까지 시간이 경과함에 따라 많이 변형되어 있는 것을 알 수 있었다. 1992년도 종자에서 이형주를 제거하고 원형의 개체로부터 자식종자를 대량으로 채종하였다. 함께 공시한 AC2258은 순수한 것으로 확인되었다. 1995년도 채종 CM334 종자에서는 비록 혼종은 되었으나 측지발생이 적은 개체들이 발견되어 이들을 개체 선발하여 역병에 저항성이며 측지발생이 적은 계통으로 육성하고 있다. A total of 31 c. chinense lines selected from 2000 screening were tested again for resistance to P. capsici but resistance was not found in the lines. A total of 26 selections from Korean land races tested 2001 spring were tested again for resistance to P. capsici. KC180, KC230, KC195 and KC194 showed moderate resistance to P. capsici. However, it was apparent on the basis of hortivultural characteristics that KC180 and KC230 had been naturally crossed with AC2258 and CM334, respectively. CM334 and AC2248 seed lots that were increased in different years were taken out and tested for resistance to improve their genetic purity because the resistant genetic resources have been showing some off-types in the population. Off-types began to be found in 1992 seed lots and the proportion and degree of the offs was increasing with time up to 2001. Plants true to the type in 1992 seed lots were selected and their inbred seeds were mass produced in a net cage in the greenhouse. AC2258 included in the experiment number of lateral branching at cotyledonary axil, although they were off from the original in the experiment together was uniform. In 1995 seed lost of CM334, plants with resistance to P. capsici and low or no number of lateral branching at cotyledonary axil, although they were off from the original CM334, were found and selection was applied to breed lines fixed in the characters.

철근 이음형 PC 보-기둥 내부 접합부의 구조적 거동에 관한 실험적 연구

김승훈,하상수,문정호,이리형,이강철,전병갑 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

In this study, new moment-resisting precast concrete beam-column joint is proposed for moderate seismic regions. It has the connection reinforcing bars, penetrated the joint and lap-spliced with the bottom bars of precast U-beam. An experimental study was carried out to investigate the joint behavior subjected to reverse cyclic loading and constant axial compressive load. Three precast beam-column interior were tested. The variables examined were the type of connection reinforcing bars and presence of transverse reinforcement in joint. Joint performance is evaluated on the basis of connection .strength, stiffness, energy dissipation, and drift capacity. Based on the test results, the precast connection is capable of matching or exceeding the performance of the monolithic connection and thereby provides the sufficient moment-resisting behavior to be applicable for moderate seismic regions.

편백 잎(葉) 정유 성분의 항균(抗菌)활성 물질 분석

조종수,김사익,윤승락,노정관,나종범,김동귀,최길동 진주산업대학교 산업과학기술연구소 2007 산업과학기술연구소보 Vol.- No.14

To investigate the antimicrobial effects of essential oil in the leaves of Chamaecyparis obtusa extractives by paper disc method, the extractives were fractionated into four portions. In antimicrobial test, essential oil in the leaves of Chamaecyparis obtusa was found to have strong inhibitory effects against the growth of Bacillus subtilis and Staphylococcus aureus. A part of analyzed inhibition components of essential oil in the leaves of Chamaecyparis obtusa from GC-MS was supposed to be α,β-pinene, α-terpinolene, camphor, β-myrcene, 1-α-terpinolene, 4-thujen-2-α-yl, limonene, Cardinene.

Redundant 2진 구조를 이용한 8 × 8-Bit 복소수 승산기의 설계

라승수,김정범 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-

A redundant binary (RB) architecture, which is optimized for the fast CMOS parallel multiplier, is proposed. This architecture enables one of to convert a pair of partial products in normal binary (NB) from to one RB number with no additional circuits. We improved the RB adder circuit so that it can make a fast addition of the RB partial products. We also simplified the converter that converts the final RB number into the corresponding NB number. The carry propagation path of the converter circuit is carried out with only a multiplexer. An 8×8-bit complex multiplier is designed with this architecture. It is fabricated by 0.6 um standard CMOS process with triple metal technology. The validity and effectiveness of the designed multiplier are verified through the MAX PLUS-Ⅱ and HSPICE simulation. The active area size is 1.55×1.45 mm2 and the number of transistors is 16,323. Under the condition of 3.3V supply voltage, the chip achieves 7.5 ns multiplication time.

장기간 항갑상선제 투여 후 임의 중단 뒤 재복용시 발생한 무과립구증 1 예

김승만;김태영;박수영;배영환;서영경 정은주;김태균;권민정;박정현;이순희 인제대학교 2011 仁濟醫學 Vol.32 No.-

Agranulocytosis, one of the major side effects of antithyroid a gents, probably occurs in less than 0.25% of cases treated with antithyroid agents. It usually occurs within the first several weeks or months after the initiation of therapy, when drug dosage is higher. Most reported cases of agranulocytosis have occurred during the first 3 months of therapy. We describe here a rare case that did not experience the side effect for 6 years of antithyroid agent treatment but presented with agranulocytosis in one month after re-exposure. It suggests that the major side effect such as agranulocytosis can occur in patients who had undergone prior uneventful antithyroid drug therapy.

토끼에서 근육주사시 입자 크기에 따른 amoxicillin의 비교 약물동태학

박승춘,윤효인,오태광,장범수,배순이,조준형,정상희,이내경,김민규 충남대학교 수의과대학 동물의과학연구소 1998 動物醫科學硏究誌 Vol.6 No.-

To investigate the pharmacokinetic difference between the two amoxicillin (AMX) particles in rabbits after intramuscular injection (i.m.), both of AMX-S (particle size: 10 ㎍) and AMX-L (particle size: 100 ㎍) were injected into New Zealand White rabbits (1.2±0.3 ㎏) at a dose rate of 10 ㎎/㎏ of body weight. In this study, serum AMX concentrations were detected by microbiological assay with E. coli BE 1186 which shows high antibiotic sensitivity. After i.m. administration, AMX-S and AMX-L were best fitted as 1-compartment model with the absorption and elimination phase. The biological half-life (T_1/2, _k10) of AMX-S is 4.06±1.09 h and that of AMX-L 4.76±0.69 h. The serum maximal concentration time (T_max) of AMX-S and AMX-L were 0.88±0.17 h and 0.77±0.11 h, respectively. Maximal AMX concentration (C_max) (AMX-S: 5.71±0.62 ㎍/㎖, AMX-L: 5.04±0.25 ㎍/㎖) in serum showed a significant difference (p<0.05). In terms of bioequivalance, however, there was no difference between the two AMX's after i.m. injection in the basis of C_max and AUC.

회전원판 반응조를 이용한 Pseudomonas sp. KS-96에 의한 gallic acid로부터 pyrogallol의 전환

안성만,김동석,정영기,임복규,이홍수,류병호 동의대학교 기초과학연구소 1998 基礎科學硏究論文集 Vol.8 No.1

In previous paper Pseudomonas sp. KS-96 isolated from the soil to bioconversion into pyrogallol from gallic acid. Continuous bioconversion of pyrogallol was carried out using rotatory disc contactor immobilized Pseudomonas sp. KS-96. Enzyme activity of gallate decarboxylase released from Pseudomonas sp. KS-96 were shown at the highest activity on 24h incubation. Culture media containing gallic acid supplied on the flow rate of 20㎖/h until thickness of cells wall reached steady state. Bioconversion rate of pyrogallol from gallic acid showed at highest level ranging from 18hr to 36h according to time courses. Continuous bioconversion of pyrogallol using rotating disc contactor was about 81% and 80% between 6 and 8 days at the feeding rate of 30㎖ per hour in the medium containing 15g/ℓ gallic acid.

國內 물푸레나무(Fraxinus rhynchophylla)와 광릉물푸레(F. densata)의 分類學的 實體

朱勝勳,張珍成,全正壹,張桂羨,李興洙 서울大學校農業生命科學大學附屬樹木園 2003 서울大學校 樹木園 硏究報告 Vol.- No.23

물푸레나무속(Fraxinus L.)에서 소엽의 길이와 너비, 동아의 털의 밀도는 속내 종 구분에 있어 주요한 형질이다. 국내에 분포하는 물푸레나무(F. rhynchophylla)와 일본의 F. japonica, 한국의 광릉물푸레(F. densata)와 일본의 F. longucuspis 간의 분류학적인 관계는 혼란이 있어왔다. 본 연구에서는 소엽의 길이와 너비, 동아의 털의 유무를 측정하기 위하여 119개의 물푸레나무와 광릉물푸레나무 표본을 이용하였다. 형질 분석 결과 물푸레나무와 광릉물푸레는 정소엽의 길이와 폭의 비율에서 차이를 보였으나, 동아의 털의 밀도와 모양, 소엽의 개수와 같은 다른 형질에서는 차이를 보이지 않았다. 그러나 한국에서 북쪽에서 남쪽으로 갈수록 소엽의 폭이 좋아지는 경향을 보이고 있다. 또한 광릉의 개체들이 타 지역의 개체들보다 동아의 길이가 길지만, 정소엽의 폭은 남쪽에서 북쪽으로 향할수록 좁아지는 양상을 띠었다. 동아의 길이는 광릉 지단이 타 집단에 비해 긴 동아를 갖는 것으로 나타났다. 정소엽의 형태와 정소엽 및 동아의 털 밀도를 비교한 결과 상호 상관관계가 존재하지 않았다. 기존에 영양 형질을 기준으로 물푸레나무와 별개의 종으로 인식되었던 광릉물푸레는 물푸레나무의 변이체인 것으로 판단되며, 일본의 F. japonica와 F. longicuspis, 한국의 물푸레나무와 광릉물푸레 역시 형태적인 차이에 있어서 변이에 대한 충분한 인식이 없었던 것으로 여겨지지만, 이에 대한 더 많은 연구가 수행되어야 한다. The characters of leaflet length, width, and hair density of winter bud are important to recognize many taxa of Fraxinus. The systematic relationships between F. rhynchophylla in Korea and F. japonica in Japan, and F. densata in Korea and F. longucuspis in Japan were confused and were not clarified yet. One hundred nineteen specimens of F. rhychophylla and F. densata were used to evaluate the correlation between the length and width of leaflet, and absence/presence of trichome in bud. From this study, the morphological discontinuity between F. rhynchophylla and F. densata was partially present only in the ratio of length and width of terminal leaflet, but other characters, such as hair density on winter bud, bud shape, and the number of leaflet, were not useful for delimitation. However, the ratio of length and width of terminal leaflet appeared to show clinal variation with changes from north to south in Korea. In general, there Although the length of winter bud was longer in Gwangneung than those in other area, there was no correlation between the morphology of terminal leaflet and hair density of terminal leaflet and winter bud. The previous species, F. densata in Korea were indistinguishable from the typical form of F. rhynchophylla on the basis on vegetative characters, rejecting continued recognition of this taxon as a distinctive species. The morphological differentiation between F. japonica and F. oongicuspis in Japan and F. rhynchophylla and F. densta in Korea was not considered sufficient to warrant recognition of either specific or varietal status, but should be further examined.