서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

장기표면의 내외봉한관과 봉한소체의 형태학적 관찰

안성훈 ( Seong Hun Ahn ),김민수 ( Min Su Kim ),이상훈 ( Sang Hun Lee ),권오상 ( O Sang Kwon ),김재효 ( Jae Hyo Kim ),소광섭 ( Kwang Sup Soh ),손인철 ( In Chul Sohn ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.1

Objective: In 1960`s Bonghan Kim`s team found BongHan(BH) ducts which were presumed as acupuncture meridians and BH corpuscles. They asserted Bonghan theory and SanAl theory which was involved in cell division and cell restoration. However, many other experiments which had been operated to demonstrate and find the existence of BH ducts had failed because of the secret of blue stain drugs. During the last several years, BongHan theory has been revived through experimental researches to find the anatomical structures of BH ducts and corpuscles by Soh`s Biomedical Physics Lab. Soh`s research team used the staining with Janus Green B, Alcian blue, nanoparticles and Acridine Orange. We used DAPI staining to find the existence of BH ducts and the corpuscles and to observe nuclear arrangement. Methods: We used japan white rabbits as experimental animals. BH ducts and corpuscles were stained with DAPI. The nucleus configuration in BH ducts stained with DAPI were observed with microscope. Results: In this study, we found thread like structures in silver white color distinguished from the blood vessels, nerves and lymph vessels. These thread like vessels in the linear duct shape were connected to same colored mass in the ball shape. Thread like structures we found could be separated easily from the surrounding other organ mass. The nuclei of the thread like structure in DAPI staining, are about 10~20㎛ length, in rod shape and linear arrangement. Conclusion: We concluded that the thread like structure we found was same vessel reported by Soh`s research team, BongHan ducts and corpuscle.

소아 두뇌외상의 임상적 고찰

서성일,송시헌,김성호,김관태,김윤 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.2

The clinical analysis was carried out with 182 cases of craniocerebral injuries under 15 years of age, admitted at the Department of Neurosurgery, Chung Nam National Universty Hospital during the period from September, 1990 to September 1993. Following results were obtained : 1) There were 133 males and 49 females and sex ratio was 2.7% 2) Age incidence of the accidents was greatest at 6 years of age and mostly distributed to the age group between 4 to 7. 3) Seasonal peak of the accidents was at May. 4) The accident occurred mostly botween 4 P.m. and 6 P.m in a day.5) The most frequent cause of the craniocerebral injuries was traffic accident(105cases, 57.69%) 6) No deterioration of cansciousness before and after the admission was doserved in 68cases(37.36%) 7) Pupillary change was observed in 25 cases and Babinski sign was elicitable in 31cases 8) Early convulsion and vomiting were frequent symptoms in childhood. 9) Skull fracture was observed in 72 cases(39.56%) in which linear fracture was most frequent and predilection site was parietal bone. 10) The accompanying rate of skull fracture in intracranial hemorrhage was 65.54% 11) Associated injures were found in 44 cases(24.18%). The frequent ones were e xtremity fracture, clavicle fracture 12) The overall mortality was 7.14%.

원발성 유방암에서 Sodium Iodide Symporter의 발현과 ^(99m)Tc-MIBI 유방스캔의 관계

석주원,김성장,곽희숙,이창훈,김인주,김용기,배영태,김동수 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.6

목적: hNIS는 갑상선 조직 외에 다른 조직들에서도 발현된다고 알려져 있다. 유방암 세포는 그런 조직들 중에 하나이며, 그에 의한 유방암의 방사성옥소치료의 가능성이 제시되고 있다. 본 연구에서는 유방암 조직에서 hNIS의 발현정도를 알아보고, ^99mTc-MIBI 유방스캔과 hNIS의 발현 정도와의 관계를 조사하여 보았다. 대상 및 방법: 본 연구에서는 유방암으로 수술을 시행했던 56명의 환자를 대상으로 하였다. hNIS의 발현은 면역조직화학염색에 의해서 평가되었으며, 그 결과를 ^99mTc-MIBI 유방스캔의 판정 결과와 비교하였다. 결과: 전체 56명의 환자에서 hNIS의 발현율은 41.1%였다. 병리학적 진단에 의해 침윤성관상피암종이었던 49명에서의 발현율은 42.9%, 관상피내암종이었던 7명에서의 발현율은 28.6%였다. ^99mTc-MIBI 유방스캔에서 국소섭취 소견이 관찰되었던 41명에서의 hNIS의 발현율은 31.7%였다. 비정상적인 섭취 소견이 관찰되지 않았던 15명의 환자에서의 hNIS의 발현율이 의미있게 높게 관찰되었다(66.7%, p>0.05). 결론: 유방암 환자에서의 hNIS의 발현율은 그다지 높지 않았다. ^99mTc-MIBI 유방스캔에서 섭취증가 소견이 없을 때 hNIS의 발현율이 더 높았다. Purpose: Human Na^+/I- symporter (hNIS) is known to be expressed in many tissues other than thyroid gland. The breast cancer cells are one of them and the possibility of radioiodine therapy in treatment of the breast cancer may be suggested. We investigated the expression rate of hNIS and the relationship between the expression of hNIS and the finding of 99mTc-MIBI scintimammography in the breast cancer. Materials and Methods: Surgically proved 56 patients with breast cancer were the subjects of this study. The expression of hNIS were evaluated by immunohistochemistry and the results were compared to the findings of 99mTc-MIBI scintimammography. Results: Overall expression rate of hNIS was 41.1% in 56 patients. According to the pathologic diagnosis, it was 42.9% in 49 patients with invasive ductal carcinoma and 28.6% in the 7 patients with ductal carcinoma in situ. The expression rate of hNIS in the 41 cases with a focal increased uptake at he breast lesion on 99mTc-MIBI scintimammogram was 31.7%. That in the 15 cases without any abnormal uptake on the scan was significantly higher(66.7%, p<0.05). Conclusion: The expression rate of hNIS in the patients with breast cancer was not so high. The rate was higher in the patients with no increased uptake at the breast lesion on 99mTc-MIBI scintimammography. (Korean J Nucl Med 2002;36;325-32)

有機色素分子와 陰이온 界面活性劑 사이의 相互作用에 關한 吸收分光學的 硏究

송기동,김일두,박성규,김준태,김성현 조선대학교 기초과학연구소 1990 自然科學硏究 Vol.13 No.1

The metachromatic behavior of methylene blue (MB) ia aqueous solution and in the presense of sodium dodecyl sulfate (SDS) have been studied by the absorption spectroscopic method. The results are as follows. The association force of the MB molecules in aqueous solution seems to be complex of three factors, i.e., London's dispersion force, the hydrophobic interaction and the interaction between permanent dipoles it has been measured of critical micelle concentration (CMC) in aqueous solution of SDS and that of MB-SDS to be 8.0mM and 7.9mM respectively. This indifference between CMC values of the pure SDS and MB-SDS system would mean the formation of dye-rich induced micelles(drim). The spectral changes of MB-SDS system with the addition of the inorganic salts have been observed. The addition of the salt into the solution causes the redistribution of MB molecules in the complex(D_n^+ S_m^-). It would be resulted from the decrease of the stacking effect between the bound MB molecules. The spectral changes observed in the MB-SDS system with the increase of the S/D values are analyzed and the behavior of the meta band is explainsd in terms of the stacking theory and micelle formation theory

Pont 지수의 임상적 적합성에 대한 평가

김성훈,이기수 대한치과교정학회 2000 대한치과교정학회지 Vol.30 No.1

치열금의 확장은 치아의 총생 부정교합을 비발치로 치료하기 위한 방법중 하나이며, 치열궁 확장의 진단과 치료를 위하여 상악절치의 근원심 폭경으로부터 이상적인 제1소구치간 치열궁 폭경과 제1대구치간 치열궁 폭경을 예측하는 공식이 제시되어 있다. 이 연구의 목적은 제시된 공식중에서 Pont의 예측식, Schmuth의 예측식 및 Cha 들의 예측식을 정상교합의 계측과 비교하고, 이들 예측식의 임상적 신뢰성을 평가하는 것이다. 13세에서 23세사이의 한국인 태생 정상교합자의 석고모형을 대상으로 상악 절치 근원심 폭경, 제1소구치간 치열궁 폭경 및 제1대구치간 치열궁 폭경사이의 상관관계를 평가하였으며, 정상교합의 절치폭경의 합을 Pont의 예측식, Schmuth의 예측식 및 Cha들의 예측식에 대입하여 이상적 제1소구치간 및 제1대구치간 치열궁 폭경의 예측치를 산출하고, 이를 정상교합자의 그것과 비교하여 다음의 결과와 결론을 얻었다. 1.정상교합에서 상악 절치 근원심 폭경의 합 (SI) 으로부터 산출된 제1소구치간 치열궁 폭경 지수는 81.96이었고, 제1대구치간 치열궁 폭경 지수는 62.55이었다. 2.정상교합에서 상악 절치 근원심 폭경의 합 (SI)과 제1소구치간 치열궁 폭경 (PmW)사이의 상관계수는 0.50이었고, 제1대구치간 치열궁 폭경(MW)사이의 상관계수는 0.39로 모두 통계적 유의성이 있는 저도의 상관관계를 나타냈다. 3.정상교합에서 상악 절치 근원심 폭경의 합으로부터 제1소구치간 폭경과 제1대구치간 폭경의 예측을 위한 상관식은 신뢰성이 매우 낮았다 (r2 = 0.25, r2 = 0.15). 4.이상적 제1소구치간 치열궁 폭경의 예측에 있어서 Pont와 Schmuth의 예측식은 실제보다 크게 예측되는 경향을 보였으며 Cha 들의 예측식은 보다 크거나 작게 예측되는 비율이 같았다. 5.이상적 제1소구치간 치열궁 폭경의 예측이 1 mm의 오차한계 이내로 예측된 경우는 Cha 들의 예측식이 가장 높으며 (45%), Pont의 예측식과 Schmuth의 예측식은 각각 40% 와 39% 이었다. 6.이상적 제1대구치간 치열궁 폭경의 예측에 있어서 모든 예측식은 작게 예측되는 경향을 보였으며, 그 중에서도 Cha들의 예측식은 예측성이 가장 양호하였다. 7.이상적 제1대구치간 치열궁 폭경의 예측이 1 mm의 오차한계 이내로 예측된 경우는 Cha 들의 예측식이 40% 로 가장 높으며, Pont와 Schmuth의 예측식은 각각 29% 와 13% 이었다. 이상의 결과는 상악 절치의 근원심 폭경의 합으로부터 이상적 제1소구치간 치열궁 폭경 및 제1대구치간 치열궁 폭경을 예측하는 것은 임상적 신뢰성이 낮을 것임을 시사한다. Dental arch expansion is one of the method used to solve the dental crowding problem by non-extraction. Many formulae using tooth size have been suggested to predict ideal inter-premolar and inter-mortar width. The purpose of this study was to evaluate the adequacy of some upper dental arch width prediction methods, namely Pont's method, Schmuth's method and Cha's method. The sample consisted of the casts of 119 Korean young adults who had no muscular abnormality, no skeletal discrepancy, and Angle's Class I molar relationships. Measurements were obtained directly from plaster casts; they included mesiodistal crown diameters of the four maxillary incisors, as well as maxillary inter-first-premolar and inter-first-molar arch widths as specified by Pont. The correlation coefficients between the sum of incisors(SI) and upper dental arch width were calculated. The differences between predicted width and actual width were classified as overestimated, properestimarted, and underestimated. The data obtained from each group were analyzed for statistical differences. The results were as follows : 1.Upper dental arch width indices were calculated from SI in normal occlusion (81.96 : premolar index, 62.55 : molar index). 2.Low correlations between SI and arch width were noted in normal occlusion (0.50 in the inter-premolar width, 0.39 in the inter-molar width). 3.Pont's formula and Schmuth's formula tended to overestimate the inter-premolar width. A more even distribution of estimates was noted in Cha's formula. 4.Cases within ±1 mm range of observed inter-premolar width were 45% in the Cha's formula, 40% in the Pont's formula, and 39% in the Schmuth's formula. 5.All formulae had a tendency to underestimate the inter-molar width, but Cha's formula had better predictability than others. 6.Cases within ±1 mm range of observed inter-molar width were 40% in the Cha's formula, 29% in the Pont's formula, and 13% of Schmuth's formula. The data presented in this study does not support the clinical usefulness of ideal arch width prediction methods using the mesiodistal width of maxillary incisors.

취업증진을 위한 기사자격증 취득 및 위업자료의 체계적 구축 및 운용 방안

김성일,구경완,장종국,사공성대,황재효,류승헌 永同大學校 1997 硏究論叢 Vol.3 No.1

국가기술자격증 취득을 위한 효과적인 강의 지도를 실시하고, 이와 병행하여 기업체의 구인정보와 취업 대상자의 진로 의사 정보를 정확하게 파악하여 데이터베이스화하고 기업체에 본 대학을 상세히 홍보함으로써 취업증진을 도모한다. We make effective lectures for obtaining a national technical qualification and construct the database of job information that contain the information about companies and students respectively. Also We propagate Youngdong University to the companies for promoting the employment of students.

주사용 발프로산 나트륨(DEPAKINE^(�)) 투여에 의한 항전간 효과의 유효성 및 안전성에 관한 임상적 연구

김성호,서성일,송시헌,김관태,김윤 최신의학사 1994 最新醫學 Vol.37 No.8

跆拳道 품새의 氣功修鍊 役割에 關한 文獻的 硏究

김경지,성헌제 慶熙大學校 社會體育硏究所 1994 體育科學論叢 Vol.- No.7

1. Conclusion This study is focused on the plans to overcome physical difficulties of the middle, elderly people such as 『various diseases (especially from lack of exercise), stress of tension』, and to lead a more healthy life through the literature study of 'Taekwondo Pumsae' and 'Kikong' practice. Below are the results of the literature study. 1)'Taekwondo' and 'Kikong' have a close relation between. These two have come up to now in defferent realms in spite of development almost at the same time. The former has developed as a self-defense instinct, with the prosperity and decline of nation, while the latter has developed toward safety of mind, medical treatment, and physical health. However, both have developed through the process of becoming congruous into one by the depth of practice and, also, are rooted deep in orientalism 2)'Pumsae' practice of 'Taekwondo' and 'Kikong' practice are aimed at physical sturdiness of higher level. 3) The ultimate purpose of 'Taekwondo' and 'Kikong' practice is reaching the stage of right 'Do'. This can be realized by the fact that 'Kikong' is used both in the practice method of taoism, the zen sect of Buddhism, and Buddhism and in the practice of military arts 'Kikong'. 4) 'Kikong' practice is unconsciously performed in 'Taekwondo' pratice. Taken for examples are the preparatory acts to relax the body in 'Taekwondo' practice, the breath actions taken in 'Pumsae', and the mind and breath anangement in long-relayed actions which are intermittent in 'Pumsae'. 5) There are some points in the methods of 'Kikong' practice which need improving because of Pumsae characteristics in 'Taekwondo Pumsa-e'. 2. Improvement Plans of 'Kikong' practice in 'Taekwondo' will be considered on the basis of these aspects. Hypotheses below are set up because the 'Ki' practice is closely related to breathes, and the former itself can never be materialized without the latter; also, many physical problems, as explained in the pervious chapter, are brought up as a man ages. 1) Rapidity or intenseness of action should be removed of the previous 'Pumsae'. 2) A breath is taken for the beginning and end of an action each. 3) The foot is raised with its end unfolded and power is added to its end at the last point of time, as to the speed and the location of the foot end in the action of 'Palchaki'. 4) 2 to 3 actions which are sequentially taken at one verbal order in the present 'Pumsae' should be all divided, and executed at one breath. 5) The hand movement are calmly connected into a half circle in the time of breath. 6) Division of actions is maintained uniformly to breathes. 7) Preparatory actions are slowly taken in the power-removed condition, and power is exerted at the last part in the offense action. 8) The fists are lightly clenched, not firmly, and power is exerted on them in the 'Jirki' action at the same last part as in the 'Palchaki' action. After the hypotheses above is materialized a definite approach can be tried to 'Taekwondo' and 'Ki'. Below are the definite plans. First, restore the function of breath from the beginning before the entrance into 'Palchaki' -a practical action of 'Taekwondo', or a preparatory attitude. This means the practice of breathe-in and breath-out, implying that one breathes consciously to have breathes reach the navel and the abdomen. Second, the slackening exercise of the body is added to the previous preparatory exercise-the 'Yoga' exercise. Third, 'Taekwondo' is the physical sport in movements and one needs to learn how to breathe to the basic actions. One breathes in at preparatory actions and breathes out in the progress. A little breath should remain at the end of the last action. Fourth, current of actions should be as natural as water once in the practical 'Pumsae', and should not face the situation like a rush of blood in the face, or the out-of-breath situation. Fifth, although even better is raising the foot as high as possible by skill, it is generally lifted to one's waist and, then power is given to its end. Sixth, in the performance of every action one tries to let the physical actions done softly and naturally, not by force.