GO-62 : Lower extremity edema in patients with endometrial cancer

( Myong Cheol Lim ),( Jeong Seon Lee ),( Jung Nam Joo ),( Sang Soo Seo ),( Sok Bom Kang ),( Sang Yoon Park ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-

The objective of this study was to investigate clinical manifestations of lower extremity edema (LEE) in endometrial cancer Medical records for LEE and/or responses to the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) were evaluated in 177 patients with endometrial cancer Patients had a median age of 53 years. Sixty-seven patients (37.9%) had past (9 patients, 13.4%) and/or current patient-reported LEE (58 patients, 86.6%). Symptoms reported on the GCLQ in over 20% of respondents were swelling, numbness, aching , and heaviness. GCLQ total symptoms score was significantly higher in patients with current LEE. Most of the LEE (43/67, 64.2%) developed within 12 months after surgery and LEE lasted more than 6 months in most patients (56/59, 94.9%) Prospective clinical trials are needed to know the clinical significance, impact on quality of life, and preventive strategy of LEE in patients with endometrial cancer

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

GC/NPD를 이용한 다성분 잔류농약의 동시분석

김우성,이선화,김상엽,정동윤,김재이,이영자,이홍재,정성욱,박흥재 한국환경과학회 2003 한국환경과학회지 Vol.12 No.10

Pesticides were extracted from samples with 70% acetone and methylene chloride in order, and then cleaned up via open-column chromatography apparatus packed with fiorisil, and finally analyzed simultaneously the organophosphorus pesticides using GC/NPD, Ultra-2 and Ultra-1 fused silica capillary columns were used to separate and identify the products. Recovery of most analytes from soybean sample, taken from pesticide residues well, was greater than(80%) for all except(6) analytes. This method can simultaneously determine multiple pesticides with a high degree of accuracy and precision.

모 주물공장 근로자의 작업공정별 분진폭로량, 자각증상 및 건강진단판정 비교

이범식,조영채,변정식,김동현,원선혜,김정윤 忠南大學校 環境問題硏究所 1995 環境硏究 Vol.13 No.-

The relationship among dust exposure dose, special health diagnosis results and subjective symptom questionaire survey for 109 casting foundry workers supervised by a local laber office has been studied from august to october 1993. Subjective symptom, dust exposure dose and health examination evaluation of respective working processes have been analized and concluded as follows; 1. Metal fume concentration in melting process measured 3.21±1.46㎎/㎥ is under threshould limit value(TLV;5.0㎎/㎥), casting sand dust measured in molding and desanding process is 5.8 ±3.41㎎/㎥ and 9.69 ±2.64㎎/㎥ which is 3-5 times higher than TLV(2.0㎎/㎥), metal fume, welding fume and metal dust in finishing process measured 9.34 ±1.32, 13.73 ±16.97 and 10.17 ±3.50㎎/㎥ respectively, which are also 2-3 times higher than TLV(5.0㎎/㎥). 2. The complain rate subjective symptoms appeal evaluated for finishing process are 35.9%, 46.2%, 27.2% and 42.2% for eye smptoms, respiractory, skin, general symptom respectively and the rates above express the highest values and the complain rates for melting process are 24.4%, 37.5% and 35.7% for eye smptoms, respiratory and mental system respectively and for molding and desanding it is 24.3%. 3. Perceived occupational disease rate is found 0.9% with are out of 109 worker surveyed who have been exposed in metal fume of finishing process. 4. 33.0% of workers surved are found to require close examination, the worker of hepatopathy suspected are 21.4% which is the highest and 3.7% for circulatory disturbance suspected. 5. The statistically significant variables in general chracteristics that affect health examination evaluation are smoking(P<0.001), respirator put-on (P<0.05) and working career(P<0.05). 6. Cough(P<0.001), "headache"(P<0.05) and "easily skin exchange by slight stimulation" (P<0.05) are statistically significant to the subjective symptom variables affect health examination evaluation.

그리스 도예의 양식 전개와 미적특성

이점찬,허정선 한국공예학회 1998 조형디자인연구 Vol.1 No.-

The concept of arts of Greece is disparate from C. Batteus's concept of arts as fine arts, which has been accepted since the 18th century. Called 'techne', the arts of Greece entail the development of a skill that is as pragmatic as it is rational. Pottery making essentially requires the observance of rational rules more than do other artistic skills. Hence, it is very significant to study the stylistic development and aesthetic properties of the pottery art of Greece. Our study especially centers on the pottery of the Archaic period(B.C. 8-6C) among the three periods; Archaic, Classic(B.C.5-4C), and Hellenistic(B.C.3-1C). The pottery of Archaic period is charicterized by geometric patterns and semi-stylized figures on the surface. Most art historians may likely pay special attention to the Classic period, its style being in conjuntion with the canon of art in western art history. This study, however, will find out the significance of the geometric patterns the Archaic period. Being not contrary to the abstract trend in modrn art, the geometric style in Greece pottery should be reconsidered.

Anemone의 花粉 2型現象과 葯培養에 關한 硏究

李炳基,高正愛,殷鍾旋 全北大學校 1987 論文集 Vol.29 No.-

In order to investigate the effects fo anther stage, optimal basic media, kinds and concentrations of plant growth regulators, sucrose concentrations for callus and embryo formation, pollen dimorphism and low temperature pretreatment of floral bud on the emergence of embryogenic S pollen of Anemone coronaria in vivo or in vitro, anthers of Anemone coronaria were cultured in Murashige & Skoog's(M&S) and Bourgin & Nitsch's(H) basic media with the combination of auxins and cytodinins. The measurement of anther length could be reliable criterion in determining the optimal anther stages, while floral bud length and anther color could not be a reliable criterion because same sized floral buds showed various degree of microspore development. M&S basic media was more effective on callus formation than H basic media. The addition of plant growth regulators of NAA and BA with M&S basic media was effective on callus formation than 2,4-D and kinetin. The best results was obtained from the combination of 0.5mg/l NAA and 2.0 mg/l BA. The best response of calus formation was obtained from 3% sucrose concentration on M&S basic medium supplemented with 0.5mg/l NAA and 2.0mg/l BA. B type of S pollen was formed on each anther stages except anther stage I in vitro. Callus formation was effective just before or just after at first pollen mitosis, while callus formation was less effective at tetrad or mature pollen staes. Low temperature pretreatment on the first pollen mitosis anthers with 1℃ or 5℃ for 10 days induced above 25% of S pollen. Embryogenic S pollen were divided mostly into A type at 10℃ for 10 days pretreatment and rate of B type pollen was appeared 4.3% which was 5 times more than control. Callus formation was effective at 10℃ for 10 days pretreatment.

G-CSF로 체내 증폭된 골수를 이용한 동종 조혈모세포이식

이종욱,김정아,민창기,김희제,엄현석,박수정,서정곤,김동욱,홍영선,민우성,김춘추,김동집 대한조혈모세포이식학회 1998 대한조혈모세포이식학회지 Vol.3 No.2

연구배경: 이식시 주입되는 골수세포수는 생착 속도 및 생존율과 밀접한 관계가 있으나, 임상적으로 환자의 체중이 공여자에 비해 지나치게 많을 때 단위 체중당 환자에게 주입되는 세포의 양이 적어 문제가 될 수 있다. 방법: 저자들은 가톨릭 조혈모세포이식 센터에서 동종 골수이식을 시행한 환자들 중 환자의 체중이 공여자에 비해 10kg이상 많은 경우 골수 채취 전에 공여자에게 3일간 피하로 G-CSF(10ug/kg/day)를 투여하여 골수를 체내(in vivo) 증폭시킨 후 골수이식을 시행한 25예의 환자를 대상으로 고식적인 방법으로 골수이식을 시행한 위험인자가 일치되는 대조군과 비교하여 이식된 세포수, 혈구의 회복속도 및 이식편대 숙주반응(GVHD)의 발생율, 그리고 생존율 등을 비교 분석하였다. 결과: 단기간의 G-CSF 투여로 증폭된 골수의 총 유핵세포수, 단핵구수는 대조군에 비해 3-5배, CD34 + 세포수는 6배 증폭되었으며, 두 군간에 세포의 면역표현형(CD4, CD5, CD7, CD8, CD20)의 차이는 없었다. 중성 백혈구 수가 0.5×10^(9)/L 이상 회복되는 시기는 두 군간의 차이가 없었으나(15.5일 vs 16일; p=0.131), 혈소판 수가 30×10^(9)/L 이상으로 회복되는 시기는 G-CSF 투여군에서 의의있게 단축되었다(20일 vs 26일; p=0.013). 두 군간 급성 및 만성 GVHD의 발생률과 정도의 차이는 없었으며, 이식 후 재발 및 생존율의 차이도 없었다. 결론: 이식전 공여자에게 단기간 G-CSF를 주사하여 생체내에서 골수 조혈모세포를 증폭시킨 후 이식하는 방법은 공여자와 환자의 심각한 체중 차이로 인해 단위체중당 이식되는 조혈모세포양이 부족한 환자들에게 안전하고 유용한 방법일 뿐만 아니라 GVHD의 증가 없이 빠른 혈구회복을 기대할 수 있는 이식기법이라고 생각한다. 향후 증폭된 골수 조혈모세포의 특성 연구 및 이의 효용성을 확인하기 위한 전향적인 연구가 필요하리라고 생각된다. Background: Sufficient stem cell doses are necessary to overcome engraftment failure in allogeneic bone marrow transplantation(BMT). Cell doses harvested may depend on body weight (BW) difference between donor and recipient. In practice, it is important to achieve large number of stem cells from donor who were lower BW than that of recipient. Methods: We have tried to inject G-CSF(10ug/kg/day) subcutaneously for 3 days to the allogeneic donor with lower BW than recipient before harvest to increase BM inoculum. BM was infused into patients without any manipulation on day 5. A total 25 patients were enrolled; 12 AML, 6 ALL, 5 SAA and 2 CML(expansion group). We compared the expansion group with 25 historical control patients, matched for diagnosis and clinical characteristics, who underwent unprimed BMT. Results: Recipient BW is not different between the expansion and control group. However, allogeneic donors in the control group weigh heavier than those in the expansion group. The yield of TNC, MNC, and CD34^(+) cells from G-CSFprimed BM was significantly higher than that from unprimed BM. There was no difference in immunophenotyping analysis(CD4, CD5, CD7, CD8, CD20) between two groups. The median time reaching to absolute neutrophil count more than 0.5×10^(9)/L was not different(15.5 vs 16 days: p=0.131), but time to platelet recovery more than 30×10^(9)/L was significantly shorter for the patients who received G-CSF-primed BM (20 vs 26 days: p=0.013). There was no difference in the incidence of acute and chronic GVHD, relapse rate and overall survival between the two groups with a median follow-up of 13 months. Conclusion: These data suggest that the short-term administration of G-CSF to an allogeneic donor prior to BM harvest seems to be a feasible method to achieve an adequate number of cell doses for patients who weigh higher than donors. Randomized, prospective study is needed to evaluate the efficacy of allogeneic BMT using in vivo expansion of BM by G-CSF.

초등학교 특수학급에서 특수아동의 행동통제에 관한 문화기술적 연구

이정선,김종심 국립특수교육원 2003 특수교육연구 Vol.10 No.1

본 연구는 초등학교 특수학급에서 특수교사는 특수아동들을 어떻게 통제하고 특수아동들은 이에 어떻게 대응하는지를 분석하는데 목적이 있다. 이러한 연구 목적을 달성하기 위해 약 12개월 간 전라남도 H군에 위치한 Happy초등학교의 특수학급을 대상으로 문화기술적 방법으로 자료를 수집하고 분석하였다. 학습지도와 생활지도로 나누어 바람직한 행동을 강화하고 바람직스럽지 못한 행동을 줄이는 특수교사의 통제 전략과 특수아동의 대응 전략을 분석하고, 통제의 발생원인과 의미에 대해 분석하였다. 일반학급에서의 학생통제와 구별되는 특수아동 통제의 특징을 밝힘으로서 특수학급에서 효과적인 통제방식으로 강압적 통제와 인간 중심적 통제의 조화로운 활용을 제안하였다. The purpose of the study is to describe the phenomena of exceptional children's control, and to explore the meaning and the distinctive features of the control in a special classroom of the elementary school. For this purpose, the study proposed the three research questions, i. e., control and coping strategies, the meaning of control, and features of exceptional children's control. The study was conducted by ethnographic research method for 12 month in the special classroom(resource room) of the Happy Elementary School located in Chonnam Province. Ethnographic data were collected and analyzed by participant observation and in-dept interview. Major findings can be summarized as follows: First, teachers' control strategies for the exceptional children can be divided into teaching subjects and guidance area. And special educators implemented both (1) control strategy of the reinforcement for desirable behaviors and (2) for the decrease of undesirable behaviors among exceptional children. Second, students in the study tried to copy with the teachers' control by implementation of (1) positive opposition, (2) negative opposition, and (3) no reaction strategies. Third, special educators and exceptional children's recognition on the cause of humanity oriented control were the same as (1) encouragement vs. doing well (2) prevention vs. caring for (3) concern vs. love. But both of their recognition on the cause of coercive control are different: (1) short endurance vs. boring (2) lake of effort vs. difficulty of subject (3) individual character vs. teaching method. Fourth, special educators and exceptional children interpreted cohesive control as the same:‘encouragement’vs.‘love’. But their interpretations of the coercive control were different, i. e., education' vs.‘letting off steam’. Fifth, the control strategies of special classroom were different from that of integrated classroom: (1) individual control vs. group control (2) humanity oriented control vs. rule oriented control (3) preventive control vs. prescriptive control. In conclusion, this study suggests that the most effective control in special classroom is the harmonious implementation of the humanity oriented control and the coercive control.

가정-학교-지역사회의 사회ㆍ문화적 관계 : 콜맨의 사회자본을 중심으로

이정선 한국교육인류학회 2001 교육인류학연구 Vol.4 No.2

콜맨(Coleman)과 브루되(Bourdieu)의 사회자본론의 비교와 한국교육에 주는 시사점

이정선 광주교육대학교 초등교육연구소 2001 初等敎育硏究 Vol.16 No.1

The primary purpose of the study is to explore the theory of social capital proposed by Bourdieu and Coleman, and to compare the differences and similarities between two theoretical orientations, Bourdieu and Coleman. Bourdieu proposed three different forms of capital: economic capital, cultural capital, and social capital. He also presented that cultural capital exists in three forms: embodied state, objectified states, and institutionalized states. He defined social capital as the aggregate of the actual or potential resources which are linked to possession of a durable network of more or less institutionalized relationships of mutual acquaintance and recognition. By contrast, Coleman proposed three different forms of capital: physical capital, human capital and social capital. And he referred social capital as a variety of different social resources that children have available to them in their family and community, including positive parent-child interaction at home, and social networks and interactions between adult members of the community. The similarities and differences of the two perspectives have been compared according to theoretical context, structure, characteristics, emergence condition, form and measurement of the conception. For the explanation of differences, it is crucial to note that bourdieu's conception of social capital derives from his analysis of culture and education of France, which is characterized as structuralism, giving his theoretic analysis in a very abstract way. By contrast, Coleman develops his conception from the analysis of American education, culture and society, which emphasizes empiricism-oriented value and presents it in an less abstract way. As a conclusion, in so far as the relationships(a form of social capital) give Korean significant meaning in their way of livings and schooling, and since the social capital is a crucial for the enhancement of educational result, it is suggested that we need to find appropriate way to increase social capital at home, in school, and in the community. Implications and the way of implementing social capital in educational settings are proposed in the conclusion section recovering trust relationships among school members, securing home and community partnerships, establishment of cooperation system and love triangulation among home-school-community.