GO-62 : Lower extremity edema in patients with endometrial cancer

( Myong Cheol Lim ),( Jeong Seon Lee ),( Jung Nam Joo ),( Sang Soo Seo ),( Sok Bom Kang ),( Sang Yoon Park ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-

The objective of this study was to investigate clinical manifestations of lower extremity edema (LEE) in endometrial cancer Medical records for LEE and/or responses to the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) were evaluated in 177 patients with endometrial cancer Patients had a median age of 53 years. Sixty-seven patients (37.9%) had past (9 patients, 13.4%) and/or current patient-reported LEE (58 patients, 86.6%). Symptoms reported on the GCLQ in over 20% of respondents were swelling, numbness, aching , and heaviness. GCLQ total symptoms score was significantly higher in patients with current LEE. Most of the LEE (43/67, 64.2%) developed within 12 months after surgery and LEE lasted more than 6 months in most patients (56/59, 94.9%) Prospective clinical trials are needed to know the clinical significance, impact on quality of life, and preventive strategy of LEE in patients with endometrial cancer

골다공증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이남수,이상건,이상범,이상우,이선정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : As the average lifespan of human increases, osteoporosis and osteoporosis-related fractures have become major health care problems. Despite recent advances in medical treatment, few studies have assessed the recognition of osteoporosis in general adults. This study examined the recognition of osteoporosis and analyzed the relating factors. Method : A population-based sample of 1086 adults in Asan-city, Korea was investigated with questionnaires and height, weight, Information regarding the general characteristics(gender, age, economic state), lifestylef exercise, smoking, alcohol),medical history(progestin, GH, steroid, calcitonin, PTH), demographic parameter, obesity, stress, and family history was collected through an interview using a structural questionnaire. The level of obesity was measured by the body mass index(BMI). BMD(Bone mineral density) at the lumbar spine and femoral neck was measured by dual energy X-ray absorptiometry. Osteoporosis was considered to be T-score below -2.5. Results : The prevalence of osteoporosis increased progressively with age, decreased with BMI and predominant in women by the result of x^(2) -test, T-test. Age, weight, BMI were significantly correlated with osteoporosis by the result of Pearson correlation ana1ysis(P<0.05). And age, gender, BMI, family history of osteoporosis were proved to be significant risk factors of osteoporosis by the result of multiple logistic regression(P<0.05). Conclusion : These results suggest that age, gender, BMI might be the most important risk factors of osteoporosis. And the history taking about family history of osteoporosis is helpful for diagnosing osteoporosis.

간암 환자에 합병된 Citrobacter braakii 패혈증 1례 보고

이해미,배성하,이수남,이정우,신아영,류시영,이수연,윤문희,한선영,한남익,이영석,유진홍 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Citrobacter species is a gram-negative bacilli that can cause opportunistic infections in immunocompromised hosts. Citrobacter braakii refers to the genomospecies 6 of the Citrobacter freundii complex. There are no detailed studies on infections caused by this newly identified specific genetic species in Korea. We herein report a case of a patient with hepatocellular carcinoma who, after undergoing transcatheter arterial chemoembolization, developed biloma which later progressed to C.braakii sepsis and did not respond to treatment. To our knowledge, this is the first reported case in Korea on C. braakii infection resulting in septic shock in a patient with malignancy in Korea.

곰솔(Pinus thunbergii )에서 소나무재선충병 예방을 위한 나무주사용 약제선발

이상명(Sang Myeong Lee),김동수(Dong Soo Kim),이상길(Sang Gil Lee1),박남창(Nam Chang Park),이동운(Dong Woon Lee) 한국농약과학회 2009 농약과학회지 Vol.13 No.4

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

중등학교 체육수업 운영실태와 문제점 및 미래의 과제

이광재,김윤래,김승재,황향희,김수남 江原大學校附設 體育科學硏究所 1996 江原大學校附設體育科學硏究所論文集 Vol.- No.20

The purpose of this study was to offer the basic materials on the secondary physiscl education. The subjects were 129 physiscl education teachers at K provience. The results were as follows: In teaching learning methods, the more educated experience teacher had the more improvement feeled. In the degree of difficulty of current physiscl curriculum, the more educated experience teacher had, the higher it was to be thought. In the goal achievement, the more educated experience had, the more it affected the goal achievement. The efficiency and ability of methods was not shown a significant difference among educated experience group, but shouled be consider it. The equipment and implement of goal achievement was not show a significant difference among educated experience group, but should be consider it. The evaluation of propriety and objectivity and on psychomotor, affective, and cognitive domain was not shown a significant difference.

원심모형시험에 의한 복개터널 복공의 변위특성에 관한 연구

이명욱,박병수,이종호,유남재 강원대학교 산업기술연구소 2003 産業技術硏究 Vol.23 No.A

This thesis is results of experimental works on the behavior of the cut-and-cover tunnel. Centrifuge model tests were performed to simulate the behavior of the cut-and-cover tunnels having cross sections of national road and subway tunnels Model experiments were carried out with changing the cut slope and the slope of filling ground surface Displacements of tunnel lining resulted from artificially accelerated gravitational force up to 40g of covered material used in model tests, were measured during centrifuge model tests In model tests. Jumunjin Standard Sand with the relative density of 80 % and the zinc plates were used for the covered material and the flexible tunnel lining. respectively Basic soil property tests were performed to obtain it's the property of Jumumjin Standard Sand Shear strength parameters of Jumunjin Standard Sand were obtained by performing the triaxial compression tests Direct shear tests were also carried out to find the mechanical properties of the interface between the lining and the covered material Compared results model tests estimation with respect to displacements of the lining

최적화된 허프만 엔트로피 코딩을 적용한 JPEG영상 압축 기법의 구현에 관한 연구

이종수,이남용 울산대학교 1997 공학연구논문집 Vol.28 No.1

국제표준인 JPEG영상압축기법에서는 4가지 유형의 프로세스로 베이스라인, 확장 DCT기반, 무손실, 계층적 프로세스들을 제시하고 있는데, 이 중에서 베이스라인 프로세스들이 널리 사용되고 있다. 이 베이스라인 프로세스들을 JPEG전문가 그룹(Independent JPEG Group)이 1992년에 구현하는데 그 구현기법은 압축 부호화과정에서 허프만 엔트로피 코딩을 최적화 하고자 전체적인 영상데이터를 3번 스캔(Scan)하고 있다. 본 논문에서는 전체적인 영상 스캔을 2번하여 압축 부호화할 수 있는 구현기법을 제시하며, 이 기법에 의해 영상압축에 소요되는 시간을 약 2.8% 감소시킬 수 있음도 보여준다. The International Standard IS10918-1 called JPEG offers 4 types of processes, baseline, extended DCT-based, lossless, and hierarchical. Among these processes, the baseline processes which is used widely for still image compression are implemented by the Independent JPEG Group of image compression coding experts in 1992. The implementation, to optimize the Huffman entropy coding while encoding an image scans the entire image data three times. In this paper, we propose to use an implementation technique scan the entire image two times and we show that we can save about 2.8% of time required to encode image.

GPS에 의한 이동물류의 실시간 추적에 대한 연구

이남수 철도전문대학교 2004 論文集 Vol.19 No.-

This study is management of containers which are used frequently, for efficient logistics management in Customs Free Zone. Positioning methods and wireless data communication methods were analyzed and the most suitable logistics management method was suggested. Then, logistics management system was developed and its capacity was analyzed through a model test. According to the result of model test, mostly precise positioning was possible on the road around container yard through map matching even the precision of used GPS instrument was row. And monitoring of container position was possible at container yard and which layer a container was heaped up. Consequently, logistics management system would be more efficient when it is used more precise method like inverted DGPS.

영어 등위구조에서의 추출 현상

이남근,정수영 조선대학교 인문학연구소 1998 外國文化硏究 Vol.21 No.1

등위구문은 피접속요소가 서로 대등한 문법적 관계로 접속되는 구조로서 모든 언어에 산재하는 현상으로 많은 언어이론의 연구대상이 되어왔다. 그러나 등위구문을 분석함에 있어서 어떠한 시각에서 접근할 것인가에 대해 견해는 아주 다양하다. 현대 통사론에서 등위구문은 매우 중요한 문제로 다루어져 왔으며 가장 논란이 많은 문제 중의 하나일 것이다. 통사적인 제약이 가해져서 추출이 이루어진다고 판단하는 견해와 의미론적인 또는 화용론적인 관념들이 적용되어서 등위구문에서의 추출이 이루어진다는 견해등이 있다. Ross(1967)가 등위구조제약과 같은 조건을 제시한 이후로 지금껏 많은 학자들이 영어의 등위구조에서의 추출현상을 여러 각도에서 연구를 거듭하여 왔다. 그중에는 등위구조에서의 추출을 의미론적인 면과 화용론적인 면에서 접근하는 학자들이 많이 있다. 이 논문에서는 Lakoff(1986)나 Goldsmith(1985)와 같은 학자들의 의미론적인 입장과 Schmerling(1976)의 화용론적인 입장에서 영어에서의 등위구조의 추출현상을 다룬다. 영어의 등위구문에서의 추출 현상을 본석함에 있어서 이 세가지 측면에서의 분석을 논의하고 각각의 문제점을 제시하고자 한다. Coordinate structures consist of more than two conjuncts. Ross suggested that a conjunct cannot be moved and any element in a conjunct cannot be extracted from that conjunct. The first part of the Coordinate Structure Constraint, the Conjunct Constraint, prevents extraction of a whole conjunct, and the second part, the Element Constraint, prohibits extraction of any element in a conjunct. But not all languages follow that constraint. Ross admitted there is an exception : extraction out of conjuncts is possible only if the extraction is Across The Board. That is, the extraction out of coordinate structures is well-formed only if elements are extraction out of coordinate structures is well-formed only if elements are extracted out of all conjuncts. Violations of the Element Constraint are allowed just in case the ATB condition is met. But not all sentences follow the Coordinate Structure Constraint, the exception of that constraint being Ross's Across The Board. Thus, the fundamental problem is raised of whether the coordinate structure constraint really exists. On this, Goldsmith and Lakoff suggested that the extraction from the coordinate structure can be justified if coordinate sentences are related with some sort of semantic or pragmatic conditions instead of syntactic constraints. It is accepted that coordinate sentences have something to do with some semantic or pragmatic presuppositions like sequentiality.